CHEMBL322256


SMILES c1ccc(COC[C@@H]2CC[C@@H](c3c[nH]cn3)O2)cc1
InChIKey RETVAMKTDRMQFH-ZFWWWQNUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 258.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 4.98 4.99 5.0 ChEMBL
H4 HRH4 Human Histamine A pKi 4.67 4.69 4.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 5.0 5.01 5.02 ChEMBL
H4 HRH4 Human Histamine A pEC50 4.89 4.89 4.9 ChEMBL