CHEMBL3634019


SMILES C[C@H](NC(=O)COc1cc(C(F)(F)F)c2c(-c3ccccc3)n[nH]c2n1)c1ccccc1
InChIKey KFHGSCZEZXGFSX-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 440.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.7 6.7 6.7 ChEMBL
OX1 OX1R Human Orexin A pKd 6.52 6.65 6.79 ChEMBL
OX2 OX2R Human Orexin A pKi 7.37 7.37 7.37 ChEMBL
OX2 OX2R Human Orexin A pKd 6.73 6.74 6.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database