CHEMBL392992


SMILES COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccccc4)cc13)CC2
InChIKey LNYCQEZPPFYNOL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 429.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.12 6.12 6.12 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.7 7.7 7.7 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.76 5.76 5.76 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.76 5.76 5.76 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 6.12 6.12 6.12 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 7.7 7.7 7.7 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database