CHEMBL105345


SMILES COc1ccccc1N1CCN(CCCCc2ccc(F)cc2)CC1
InChIKey OHHOLPBLYOJVEF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 342.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.48 8.49 8.5 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.96 8.98 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database