CHEMBL221131


SMILES CCC1(C)Cc2cccc(OCCNCc3cccc(C4=CCCC4)c3)c2O1
InChIKey VBGGWGMORHRQSH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 377.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.94 7.94 7.94 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.49 7.49 7.49 ChEMBL