(+)-CYCLAZOSIN


SMILES COc1cc2nc(N3CCN(C(=O)c4ccco4)[C@H]4CCCC[C@@H]43)nc(N)c2cc1OC
InChIKey XBRXTUGRUXGBPX-IRXDYDNUSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 437.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 6.86 7.06 7.27 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKi 9.68 9.68 9.68 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 9.16 9.52 9.87 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 7.77 7.78 7.78 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.73 7.73 7.73 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.49 8.49 8.49 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.91 7.91 7.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database