CHEMBL2365395


SMILES CC(C)c1cccc(-c2c(-c3ccc4nn(C)cc4c3)nsc2NC(=O)[C@@H]2C[C@H]2C)n1
InChIKey FYGXJVFGWUEFMS-RHSMWYFYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 431.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 6.19 6.19 6.19 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.78 6.78 6.78 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.72 7.72 7.72 ChEMBL