Purchasability


Ligand source activities (1 row/activity)

Select all ChEMBL ID Receptor Species Purchasable p-value
(-log)
Activity
Type
Activity
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Activity
Value
Unit Assay Type Assay Description Mol
weight
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H don H acc LogP Smiles
CHEMBL3717071 rxfp1_human Human No 6.0 AC50 = 1060 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
429 4 2 7 4.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)[N+](=O)[O-]
CHEMBL3714858 rxfp1_human Human No 6.0 AC50 = 1060 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
417 7 2 3 6.2 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(C)(C)C
CHEMBL3716462 rxfp1_human Human No 6.0 AC50 = 1060 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
454 5 2 7 5.0 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717071 rxfp1_human Human No 6.0 AC50 = 1060 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
429 4 2 7 4.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)[N+](=O)[O-]
CHEMBL3714858 rxfp1_human Human No 6.0 AC50 = 1060 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
417 7 2 3 6.2 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(C)(C)C
CHEMBL3716462 rxfp1_human Human No 6.0 AC50 = 1060 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
454 5 2 7 5.0 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717389 rxfp1_human Human No 6.9 AC50 = 118 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
492 7 2 8 4.9 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717389 rxfp1_human Human No 6.9 AC50 = 118 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
492 7 2 8 4.9 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717178 rxfp1_human Human No 5.9 AC50 = 1180 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
468 5 2 9 6.2 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3OC(F)(F)F
CHEMBL3717178 rxfp1_human Human No 5.9 AC50 = 1180 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
468 5 2 9 6.2 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3OC(F)(F)F
CHEMBL3715451 rxfp1_human Human No 4.9 AC50 = 11800 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
487 6 2 4 4.1 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CN=C3)I
CHEMBL3715676 rxfp1_human Human No 4.9 AC50 = 11800 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
424 4 3 6 4.6 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=C4C(=CC=C3)NC=N4
CHEMBL3715451 rxfp1_human Human No 4.9 AC50 = 11800 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
487 6 2 4 4.1 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CN=C3)I
CHEMBL3715676 rxfp1_human Human No 4.9 AC50 = 11800 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
424 4 3 6 4.6 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=C4C(=CC=C3)NC=N4
CHEMBL3716450 rxfp1_human Human Yes 5.9 AC50 = 1320 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
384 4 2 5 5.0 C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716450 rxfp1_human Human Yes 5.9 AC50 = 1320 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
384 4 2 5 5.0 C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718995 rxfp1_human Human No 5.9 AC50 = 1330 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
392 6 2 4 4.6 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC
CHEMBL3718384 rxfp1_human Human No 5.9 AC50 = 1330 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
613 10 2 9 5.7 CC(C)(C)OC(=O)N1CCN(CC1)CCOC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718995 rxfp1_human Human No 5.9 AC50 = 1330 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
392 6 2 4 4.6 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC
CHEMBL3718384 rxfp1_human Human No 5.9 AC50 = 1330 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
613 10 2 9 5.7 CC(C)(C)OC(=O)N1CCN(CC1)CCOC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718363 rxfp1_human Human No 4.9 AC50 = 13300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
340 4 2 3 4.7 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)F
CHEMBL3718363 rxfp1_human Human No 4.9 AC50 = 13300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
340 4 2 3 4.7 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)F
CHEMBL3718077 rxfp1_human Human No 5.8 AC50 = 1490 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
429 4 2 7 4.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
CHEMBL3717338 rxfp1_human Human No 5.8 AC50 = 1490 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
400 7 2 3 5.5 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C=CC
CHEMBL3718077 rxfp1_human Human No 5.8 AC50 = 1490 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
429 4 2 7 4.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
CHEMBL3717338 rxfp1_human Human No 5.8 AC50 = 1490 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
400 7 2 3 5.5 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C=CC
CHEMBL3719015 rxfp1_human Human No 4.8 AC50 = 14900 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
434 4 2 5 6.3 C1=CC=C2C=C(C=CC2=C1)C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3715750 rxfp1_human Human No 4.8 AC50 = 14900 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
375 4 2 7 3.8 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=NO3
CHEMBL3719015 rxfp1_human Human No 4.8 AC50 = 14900 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
434 4 2 5 6.3 C1=CC=C2C=C(C=CC2=C1)C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3715750 rxfp1_human Human No 4.8 AC50 = 14900 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
375 4 2 7 3.8 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=NO3
CHEMBL3718061 rxfp1_human Human No 5.8 AC50 = 1670 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
463 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)Br
CHEMBL3715489 rxfp1_human Human No 5.8 AC50 = 1670 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
409 4 2 6 4.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)C#N
CHEMBL3715203 rxfp1_human Human No 5.8 AC50 = 1670 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 4.2 CCOC1=CC=CC=C1C(=O)NC2=C(C=CC=N2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3718061 rxfp1_human Human No 5.8 AC50 = 1670 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
463 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)Br
CHEMBL3715489 rxfp1_human Human No 5.8 AC50 = 1670 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
409 4 2 6 4.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)C#N
CHEMBL3715203 rxfp1_human Human No 5.8 AC50 = 1670 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 4.2 CCOC1=CC=CC=C1C(=O)NC2=C(C=CC=N2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717211 rxfp1_human Human No 6.7 AC50 = 188 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
478 6 2 8 4.6 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717211 rxfp1_human Human No 6.7 AC50 = 188 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
478 6 2 8 4.6 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716394 rxfp1_human Human No 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
414 5 2 6 5.0 COC1=CC=CC(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718728 rxfp1_human Human Yes 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
390 4 2 6 5.0 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CS3
CHEMBL3717590 rxfp1_human Human Yes 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
419 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)Cl
CHEMBL3717723 rxfp1_human Human No 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
422 5 2 6 6.3 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3716394 rxfp1_human Human No 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
414 5 2 6 5.0 COC1=CC=CC(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718728 rxfp1_human Human Yes 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
390 4 2 6 5.0 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CS3
CHEMBL3717590 rxfp1_human Human Yes 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
419 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)Cl
CHEMBL3717723 rxfp1_human Human No 5.7 AC50 = 1880 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
422 5 2 6 6.3 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3714976 rxfp1_human Human No 5.7 AC50 = 2100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
409 4 2 6 4.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC(=C3)C#N
CHEMBL3714976 rxfp1_human Human No 5.7 AC50 = 2100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
409 4 2 6 4.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC(=C3)C#N
CHEMBL3716808 rxfp1_human Human No 5.7 AC50 = 2110 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
400 7 2 3 5.5 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C=CC
CHEMBL3719257 rxfp1_human Human No 5.7 AC50 = 2110 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
404 4 2 5 6.0 C1CCCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716808 rxfp1_human Human No 5.7 AC50 = 2110 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
400 7 2 3 5.5 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C=CC
CHEMBL3719257 rxfp1_human Human No 5.7 AC50 = 2110 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
404 4 2 5 6.0 C1CCCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718740 rxfp1_human Human No 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
404 4 2 5 5.7 CC1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715664 rxfp1_human Human Yes 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
374 4 2 6 4.4 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CO3
CHEMBL3717683 rxfp1_human Human No 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
501 7 2 9 4.4 CCOC1=CC=CC=C1C(=O)NC2C(C=CS2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3719295 rxfp1_human Human Yes 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
376 4 2 5 4.9 C1CCC(C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718740 rxfp1_human Human No 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
404 4 2 5 5.7 CC1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715664 rxfp1_human Human Yes 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
374 4 2 6 4.4 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CO3
CHEMBL3717683 rxfp1_human Human No 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
501 7 2 9 4.4 CCOC1=CC=CC=C1C(=O)NC2C(C=CS2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3719295 rxfp1_human Human Yes 5.6 AC50 = 2360 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
376 4 2 5 4.9 C1CCC(C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717089 rxfp1_human Human No 6.6 AC50 = 265 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
428 6 2 6 5.4 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717089 rxfp1_human Human No 6.6 AC50 = 265 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
428 6 2 6 5.4 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716811 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
478 8 2 8 5.0 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2CNC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3718273 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
379 5 2 2 6.2 CC(C)(C)C1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3714926 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
419 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)Cl
CHEMBL3715244 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
512 8 2 7 5.9 C1CCN(CC1)CCOC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3716871 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
401 4 2 2 5.3 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)Br
CHEMBL3716596 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
467 5 2 5 7.1 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C4=CC=CC=C4C(F)(F)F
CHEMBL3716811 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
478 8 2 8 5.0 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2CNC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3718273 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
379 5 2 2 6.2 CC(C)(C)C1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3714926 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
419 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)Cl
CHEMBL3715244 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
512 8 2 7 5.9 C1CCN(CC1)CCOC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3716871 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
401 4 2 2 5.3 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)Br
CHEMBL3716596 rxfp1_human Human No 5.6 AC50 = 2650 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
467 5 2 5 7.1 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C4=CC=CC=C4C(F)(F)F
CHEMBL3717103 rxfp1_human Human No 6.5 AC50 = 297 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
446 6 2 7 5.8 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3717103 rxfp1_human Human No 6.5 AC50 = 297 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
446 6 2 7 5.8 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3715040 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
452 4 2 8 5.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)C(F)(F)F
CHEMBL3716512 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
362 4 2 5 4.4 C1CC(C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3714999 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
448 4 2 2 5.2 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)I
CHEMBL3715105 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 3.9 CCOC1=CC=CC=C1C(=O)NC2=C(C=CN=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715040 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
452 4 2 8 5.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC=C3)C(F)(F)F
CHEMBL3716512 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
362 4 2 5 4.4 C1CC(C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3714999 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
448 4 2 2 5.2 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)I
CHEMBL3715105 rxfp1_human Human No 5.5 AC50 = 2970 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 3.9 CCOC1=CC=CC=C1C(=O)NC2=C(C=CN=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716987 rxfp1_human Human No 4.5 AC50 = 29700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
361 6 2 4 3.7 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=N3
CHEMBL3718895 rxfp1_human Human No 4.5 AC50 = 29700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
428 5 1 6 5.2 CN(C1=CC=CC(=C1)C(F)(F)F)C(=O)C2=CC=CC=C2NC(=O)C3=CC=CC=C3OC
CHEMBL3716987 rxfp1_human Human No 4.5 AC50 = 29700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
361 6 2 4 3.7 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=N3
CHEMBL3718895 rxfp1_human Human No 4.5 AC50 = 29700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
428 5 1 6 5.2 CN(C1=CC=CC(=C1)C(F)(F)F)C(=O)C2=CC=CC=C2NC(=O)C3=CC=CC=C3OC
CHEMBL3717553 rxfp1_human Human No 6.5 AC50 = 334 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
414 5 2 6 5.0 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717553 rxfp1_human Human No 6.5 AC50 = 334 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
414 5 2 6 5.0 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715551 rxfp1_human Human No 5.5 AC50 = 3340 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
357 4 2 2 5.2 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)Cl
CHEMBL3715551 rxfp1_human Human No 5.5 AC50 = 3340 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
357 4 2 2 5.2 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)Cl
CHEMBL3715097 rxfp1_human Human No 5.4 AC50 = 3740 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
419 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3Cl
CHEMBL3717655 rxfp1_human Human Yes 5.4 AC50 = 3740 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 4 2 5 5.4 CC1=CC=CC(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715139 rxfp1_human Human No 5.4 AC50 = 3740 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
457 8 3 7 4.6 CNCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715097 rxfp1_human Human No 5.4 AC50 = 3740 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
419 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3Cl
CHEMBL3717655 rxfp1_human Human Yes 5.4 AC50 = 3740 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 4 2 5 5.4 CC1=CC=CC(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715139 rxfp1_human Human No 5.4 AC50 = 3740 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
457 8 3 7 4.6 CNCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716878 rxfp1_human Human Yes 4.4 AC50 = 37400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
352 5 2 3 4.5 COC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3715535 rxfp1_human Human Yes 4.4 AC50 = 37400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
336 4 2 2 4.9 CC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3716901 rxfp1_human Human Yes 4.4 AC50 = 37400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
340 4 2 3 4.7 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=C(C=C3)F
CHEMBL3716878 rxfp1_human Human Yes 4.4 AC50 = 37400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
352 5 2 3 4.5 COC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3715535 rxfp1_human Human Yes 4.4 AC50 = 37400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
336 4 2 2 4.9 CC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3716901 rxfp1_human Human Yes 4.4 AC50 = 37400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
340 4 2 3 4.7 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=C(C=C3)F
CHEMBL3717045 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 4 2 5 5.4 CC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717803 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
463 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)Br
CHEMBL3714984 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
574 5 2 7 5.2 C1=CC=C(C(=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F)NC(=O)C3=CC=CC=C3I
CHEMBL3715901 rxfp1_human Human Yes 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
424 4 2 8 7.4 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715104 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
520 4 2 11 6.8 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
CHEMBL3718373 rxfp1_human Human Yes 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
356 4 2 5 6.6 C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717045 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 4 2 5 5.4 CC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717803 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
463 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)Br
CHEMBL3714984 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
574 5 2 7 5.2 C1=CC=C(C(=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F)NC(=O)C3=CC=CC=C3I
CHEMBL3715901 rxfp1_human Human Yes 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
424 4 2 8 7.4 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715104 rxfp1_human Human No 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
520 4 2 11 6.8 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
CHEMBL3718373 rxfp1_human Human Yes 5.4 AC50 = 4200 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
356 4 2 5 6.6 C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715081 rxfp1_human Human No 7.3 AC50 = 47 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
521 9 2 8 5.8 CCCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL1479446 rxfp1_human Human Yes 7.3 AC50 = 47 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
390 4 2 5 5.5 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715081 rxfp1_human Human No 7.3 AC50 = 47 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
521 9 2 8 5.8 CCCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL1479446 rxfp1_human Human Yes 7.3 AC50 = 47 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
390 4 2 5 5.5 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718541 rxfp1_human Human No 6.3 AC50 = 471 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
442 6 2 6 5.8 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718541 rxfp1_human Human No 6.3 AC50 = 471 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
442 6 2 6 5.8 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718811 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
386 5 2 6 5.7 COC1=CC=CC=C1NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716976 rxfp1_human Human Yes 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 4 2 5 5.4 CC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715539 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 4.2 CCOC1=CC=CC=C1C(=O)NC2=C(N=CC=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715615 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
442 4 2 5 5.9 C1C2CC3CC1CC(C2)(C3)C(=O)NC4=CC=CC=C4C(=O)NC5=CC=CC(=C5)C(F)(F)F
CHEMBL3718557 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
444 8 2 8 2.8 CCOC1=CC=CC=C1C(=O)NCCC(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F
CHEMBL3715429 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
514 8 2 8 4.7 C1COCCN1CCOC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718811 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
386 5 2 6 5.7 COC1=CC=CC=C1NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716976 rxfp1_human Human Yes 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 4 2 5 5.4 CC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715539 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 4.2 CCOC1=CC=CC=C1C(=O)NC2=C(N=CC=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715615 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
442 4 2 5 5.9 C1C2CC3CC1CC(C2)(C3)C(=O)NC4=CC=CC=C4C(=O)NC5=CC=CC(=C5)C(F)(F)F
CHEMBL3718557 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
444 8 2 8 2.8 CCOC1=CC=CC=C1C(=O)NCCC(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F
CHEMBL3715429 rxfp1_human Human No 5.3 AC50 = 4710 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
514 8 2 8 4.7 C1COCCN1CCOC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3717869 rxfp1_human Human No 4.3 AC50 = 47100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
438 5 2 8 6.6 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC(=CC=C3)C(F)(F)F
CHEMBL3716765 rxfp1_human Human No 4.3 AC50 = 47100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
370 5 2 5 5.7 C1=CC=C(C=C1)CNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717734 rxfp1_human Human No 4.3 AC50 = 47100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
308 3 2 5 3.4 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC=O
CHEMBL3717869 rxfp1_human Human No 4.3 AC50 = 47100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
438 5 2 8 6.6 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NCC3=CC(=CC=C3)C(F)(F)F
CHEMBL3716765 rxfp1_human Human No 4.3 AC50 = 47100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
370 5 2 5 5.7 C1=CC=C(C=C1)CNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717734 rxfp1_human Human No 4.3 AC50 = 47100 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
308 3 2 5 3.4 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC=O
CHEMBL3715235 rxfp1_human Human No 7.3 AC50 = 52 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
506 8 2 8 5.5 CCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715235 rxfp1_human Human No 7.3 AC50 = 52 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
506 8 2 8 5.5 CCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715526 rxfp1_human Human No 6.3 AC50 = 529 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
509 7 2 8 5.5 CCSC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715526 rxfp1_human Human No 6.3 AC50 = 529 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
509 7 2 8 5.5 CCSC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716829 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
430 6 2 4 5.1 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)N4CCCCC4
CHEMBL3716488 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
378 6 2 5 5.1 CCC(CC)C(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3716127 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
368 5 2 3 5.1 CSC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3715462 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
460 5 2 5 6.7 C1=CC=C(C=C1)C2=CC(=CC=C2)C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718514 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
380 5 2 6 4.8 CC(C)(C)OC(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3719301 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
364 5 2 2 5.7 CC(C)C1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3716813 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
364 6 2 5 4.7 CCCCC(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3716829 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
430 6 2 4 5.1 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)N4CCCCC4
CHEMBL3716488 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
378 6 2 5 5.1 CCC(CC)C(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3716127 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
368 5 2 3 5.1 CSC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3715462 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
460 5 2 5 6.7 C1=CC=C(C=C1)C2=CC(=CC=C2)C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718514 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
380 5 2 6 4.8 CC(C)(C)OC(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3719301 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
364 5 2 2 5.7 CC(C)C1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3716813 rxfp1_human Human No 5.3 AC50 = 5290 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
364 6 2 5 4.7 CCCCC(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3716260 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
376 5 2 5 6.5 C1CCC(CC1)CNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718279 rxfp1_human Human Yes 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
426 5 2 6 4.7 CC(=O)C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716563 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
434 4 2 5 6.3 C1=CC=C2C(=C1)C=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718612 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
367 4 2 4 4.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)[N+](=O)[O-]
CHEMBL3716978 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
452 4 2 8 5.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)C(F)(F)F
CHEMBL3718178 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
385 4 2 6 4.0 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CN=CC=C3
CHEMBL3716260 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
376 5 2 5 6.5 C1CCC(CC1)CNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718279 rxfp1_human Human Yes 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
426 5 2 6 4.7 CC(=O)C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716563 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
434 4 2 5 6.3 C1=CC=C2C(=C1)C=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718612 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
367 4 2 4 4.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)[N+](=O)[O-]
CHEMBL3716978 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
452 4 2 8 5.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)C(F)(F)F
CHEMBL3718178 rxfp1_human Human No 5.2 AC50 = 5930 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
385 4 2 6 4.0 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CN=CC=C3
CHEMBL3715266 rxfp1_human Human No 4.2 AC50 = 59300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
338 6 2 6 4.0 COCCNC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3715346 rxfp1_human Human No 4.2 AC50 = 59300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
486 9 2 7 5.4 CN(C)CCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717700 rxfp1_human Human No 4.2 AC50 = 59300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
400 6 2 6 5.6 COC1=CC=CC=C1CNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715266 rxfp1_human Human No 4.2 AC50 = 59300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
338 6 2 6 4.0 COCCNC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3715346 rxfp1_human Human No 4.2 AC50 = 59300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
486 9 2 7 5.4 CN(C)CCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717700 rxfp1_human Human No 4.2 AC50 = 59300 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
400 6 2 6 5.6 COC1=CC=CC=C1CNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3719197 rxfp1_human Human No 6.2 AC50 = 666 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
460 7 2 7 6.2 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3717047 rxfp1_human Human No 6.2 AC50 = 666 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
385 6 2 4 4.2 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C#N
CHEMBL3719197 rxfp1_human Human No 6.2 AC50 = 666 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
460 7 2 7 6.2 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3717047 rxfp1_human Human No 6.2 AC50 = 666 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
385 6 2 4 4.2 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C#N
CHEMBL3718470 rxfp1_human Human No 5.2 AC50 = 6660 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
428 4 2 7 4.8 C1OC2=C(O1)C=C(C=C2)C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718054 rxfp1_human Human No 5.2 AC50 = 6660 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
346 5 2 2 4.8 C#CC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3715101 rxfp1_human Human No 5.2 AC50 = 6660 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
424 6 2 5 3.4 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C
CHEMBL3718470 rxfp1_human Human No 5.2 AC50 = 6660 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
428 4 2 7 4.8 C1OC2=C(O1)C=C(C=C2)C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3718054 rxfp1_human Human No 5.2 AC50 = 6660 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
346 5 2 2 4.8 C#CC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3715101 rxfp1_human Human No 5.2 AC50 = 6660 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
424 6 2 5 3.4 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C
CHEMBL3718400 rxfp1_human Human No 7.2 AC50 = 67 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
546 7 2 11 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F)NC(=O)C3=CC=CC=C3OCC(F)(F)F
CHEMBL3718400 rxfp1_human Human No 7.2 AC50 = 67 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
546 7 2 11 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F)NC(=O)C3=CC=CC=C3OCC(F)(F)F
CHEMBL3716540 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
458 8 2 7 4.9 COCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718664 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
476 6 2 6 6.6 C1=CC=C(C=C1)OC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3715345 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
486 6 2 3 5.1 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)I
CHEMBL3715743 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 3.9 CCOC1=CC=CC=C1C(=O)NC2=C(C=NC=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716540 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
458 8 2 7 4.9 COCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718664 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
476 6 2 6 6.6 C1=CC=C(C=C1)OC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NC4=CC=CC(=C4)C(F)(F)F
CHEMBL3715345 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
486 6 2 3 5.1 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)I
CHEMBL3715743 rxfp1_human Human No 6.1 AC50 = 747 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
493 7 2 9 3.9 CCOC1=CC=CC=C1C(=O)NC2=C(C=NC=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3719005 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
385 4 2 6 4.0 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=NC=C3
CHEMBL3716990 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
452 4 2 8 5.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F)C(F)(F)F
CHEMBL3716581 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
444 6 2 7 5.0 COC1=C(C(=CC=C1)OC)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718291 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
510 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3I
CHEMBL3718498 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
463 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3Br
CHEMBL3719005 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
385 4 2 6 4.0 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=NC=C3
CHEMBL3716990 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
452 4 2 8 5.9 C1=CC=C(C(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F)C(F)(F)F
CHEMBL3716581 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
444 6 2 7 5.0 COC1=C(C(=CC=C1)OC)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718291 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
510 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3I
CHEMBL3718498 rxfp1_human Human No 5.1 AC50 = 7470 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
463 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3Br
CHEMBL3715708 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
361 6 2 4 3.4 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=NC=C3
CHEMBL3715107 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
367 4 2 4 4.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=C(C=C3)[N+](=O)[O-]
CHEMBL3717591 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
322 3 2 5 3.4 CC(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3718975 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
366 4 2 4 4.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC4=C(C=C3)OCO4
CHEMBL3715708 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
361 6 2 4 3.4 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=NC=C3
CHEMBL3715107 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
367 4 2 4 4.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=C(C=C3)[N+](=O)[O-]
CHEMBL3717591 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
322 3 2 5 3.4 CC(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3718975 rxfp1_human Human No 4.1 AC50 = 74700 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
366 4 2 4 4.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC4=C(C=C3)OCO4
CHEMBL3715001 rxfp1_human Human No 5.1 AC50 = 8380 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 5 2 5 5.0 C1=CC=C(C=C1)CC(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718643 rxfp1_human Human No 5.1 AC50 = 8380 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
348 4 2 5 3.8 C1CC1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715001 rxfp1_human Human No 5.1 AC50 = 8380 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
398 5 2 5 5.0 C1=CC=C(C=C1)CC(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718643 rxfp1_human Human No 5.1 AC50 = 8380 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
348 4 2 5 3.8 C1CC1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716980 rxfp1_human Human Yes 7.0 AC50 = 94 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
507 7 2 8 5.4 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716980 rxfp1_human Human Yes 7.0 AC50 = 94 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
507 7 2 8 5.4 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715166 rxfp1_human Human No 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
362 4 2 2 5.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC4=C(CCC4)C=C3
CHEMBL3718735 rxfp1_human Human Yes 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
462 5 2 7 4.3 CS(=O)(=O)C1=CC=CC(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718114 rxfp1_human Human No 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
384 6 2 5 6.1 C1=CC=C(C=C1)CCNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717718 rxfp1_human Human No 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
446 7 3 4 5.0 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NCC4=CC=CO4
CHEMBL3718813 rxfp1_human Human Yes 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
414 5 2 6 5.0 COC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715166 rxfp1_human Human No 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
362 4 2 2 5.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC4=C(CCC4)C=C3
CHEMBL3718735 rxfp1_human Human Yes 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
462 5 2 7 4.3 CS(=O)(=O)C1=CC=CC(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718114 rxfp1_human Human No 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
384 6 2 5 6.1 C1=CC=C(C=C1)CCNC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717718 rxfp1_human Human No 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
446 7 3 4 5.0 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NCC4=CC=CO4
CHEMBL3718813 rxfp1_human Human Yes 5.0 AC50 = 9400 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
414 5 2 6 5.0 COC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL1491180 rxfp1_human Human Yes 4.0 AC50 = 94000 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
322 4 2 2 4.6 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=C3
CHEMBL3717485 rxfp1_human Human No 4.0 AC50 = 94000 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
390 4 2 5 5.5 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=C(C=C3)C(F)(F)F
CHEMBL1491180 rxfp1_human Human Yes 4.0 AC50 = 94000 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
322 4 2 2 4.6 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=C3
CHEMBL3717485 rxfp1_human Human No 4.0 AC50 = 94000 Funct
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
390 4 2 5 5.5 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=C(C=C3)C(F)(F)F
CHEMBL3715235 rxfp1_human Human No 7.0 EC50 = 105.1 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
506 8 2 8 5.5 CCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715235 rxfp1_human Human No 7.0 EC50 = 105.1 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
506 8 2 8 5.5 CCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716462 rxfp1_human Human No 6.0 EC50 = 1060 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
454 5 2 7 5.0 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3718400 rxfp1_human Human No 7.0 EC50 = 107.3 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
546 7 2 11 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F)NC(=O)C3=CC=CC=C3OCC(F)(F)F
CHEMBL3718400 rxfp1_human Human No 7.0 EC50 = 107.3 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
546 7 2 11 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F)NC(=O)C3=CC=CC=C3OCC(F)(F)F
CHEMBL3717178 rxfp1_human Human No 5.9 EC50 = 1180 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
468 5 2 9 6.2 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3OC(F)(F)F
CHEMBL3715081 rxfp1_human Human No 6.9 EC50 = 123.7 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
521 9 2 8 5.8 CCCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715081 rxfp1_human Human No 6.9 EC50 = 123.7 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
521 9 2 8 5.8 CCCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716450 rxfp1_human Human Yes 5.9 EC50 = 1320 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
384 4 2 5 5.0 C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718363 rxfp1_human Human No 4.9 EC50 = 13300 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
340 4 2 3 4.7 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)F
CHEMBL3715203 rxfp1_human Human No 5.8 EC50 = 1670 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
493 7 2 9 4.2 CCOC1=CC=CC=C1C(=O)NC2=C(C=CC=N2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717389 rxfp1_human Human No 6.7 EC50 = 188 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
492 7 2 8 4.9 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717211 rxfp1_human Human No 6.7 EC50 = 188 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
478 6 2 8 4.6 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716394 rxfp1_human Human No 5.7 EC50 = 1880 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
414 5 2 6 5.0 COC1=CC=CC(=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL1479446 rxfp1_human Human Yes 5.7 EC50 = 1880 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
390 4 2 5 5.5 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717723 rxfp1_human Human No 5.7 EC50 = 1880 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
422 5 2 6 6.3 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3716980 rxfp1_human Human Yes 6.7 EC50 = 199.9 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
507 7 2 8 5.4 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716980 rxfp1_human Human Yes 6.7 EC50 = 199.9 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
507 7 2 8 5.4 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3719257 rxfp1_human Human No 5.7 EC50 = 2110 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
404 4 2 5 6.0 C1CCCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3719295 rxfp1_human Human Yes 5.6 EC50 = 2360 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
376 4 2 5 4.9 C1CCC(C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717089 rxfp1_human Human No 6.6 EC50 = 265 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
428 6 2 6 5.4 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716871 rxfp1_human Human No 5.6 EC50 = 2650 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
401 4 2 2 5.3 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)Br
CHEMBL3716596 rxfp1_human Human No 5.6 EC50 = 2650 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
467 5 2 5 7.1 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C4=CC=CC=C4C(F)(F)F
CHEMBL3718273 rxfp1_human Human No 5.6 EC50 = 2660 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
379 5 2 2 6.2 CC(C)(C)C1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3716512 rxfp1_human Human No 5.5 EC50 = 2970 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
362 4 2 5 4.4 C1CC(C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715105 rxfp1_human Human No 5.5 EC50 = 2970 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
493 7 2 9 3.9 CCOC1=CC=CC=C1C(=O)NC2=C(C=CN=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3718895 rxfp1_human Human No 4.5 EC50 = 29700 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
428 5 1 6 5.2 CN(C1=CC=CC(=C1)C(F)(F)F)C(=O)C2=CC=CC=C2NC(=O)C3=CC=CC=C3OC
CHEMBL3717553 rxfp1_human Human No 6.5 EC50 = 334 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
414 5 2 6 5.0 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715551 rxfp1_human Human No 5.5 EC50 = 3340 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
357 4 2 2 5.2 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)Cl
CHEMBL3717211 rxfp1_human Human No 6.5 EC50 = 358.5 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
478 6 2 8 4.6 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717211 rxfp1_human Human No 6.5 EC50 = 358.5 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
478 6 2 8 4.6 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717389 rxfp1_human Human No 6.4 EC50 = 362.2 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
492 7 2 8 4.9 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717389 rxfp1_human Human No 6.4 EC50 = 362.2 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
492 7 2 8 4.9 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715097 rxfp1_human Human No 5.4 EC50 = 3740 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
419 4 2 5 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CC=CC=C3Cl
CHEMBL3716878 rxfp1_human Human Yes 4.4 EC50 = 37400 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
352 5 2 3 4.5 COC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3715535 rxfp1_human Human Yes 4.4 EC50 = 37400 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
336 4 2 2 4.9 CC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3717045 rxfp1_human Human No 5.4 EC50 = 4200 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
398 4 2 5 5.4 CC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715081 rxfp1_human Human No 7.3 EC50 = 47 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
521 9 2 8 5.8 CCCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3718541 rxfp1_human Human No 6.3 EC50 = 471 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
442 6 2 6 5.8 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717089 rxfp1_human Human No 6.3 EC50 = 471.1 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
428 6 2 6 5.4 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3717089 rxfp1_human Human No 6.3 EC50 = 471.1 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
428 6 2 6 5.4 CCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715539 rxfp1_human Human No 5.3 EC50 = 4710 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
493 7 2 9 4.2 CCOC1=CC=CC=C1C(=O)NC2=C(N=CC=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3715235 rxfp1_human Human No 7.3 EC50 = 52 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
506 8 2 8 5.5 CCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717103 rxfp1_human Human No 6.3 EC50 = 523.1 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
446 6 2 7 5.8 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3717103 rxfp1_human Human No 6.3 EC50 = 523.1 Funct
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
446 6 2 7 5.8 COC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)SC(F)(F)F
CHEMBL3716488 rxfp1_human Human No 5.3 EC50 = 5290 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
378 6 2 5 5.1 CCC(CC)C(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3716127 rxfp1_human Human No 5.3 EC50 = 5290 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
368 5 2 3 5.1 CSC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2NC(=O)C3CCCCC3
CHEMBL3716813 rxfp1_human Human No 5.3 EC50 = 5290 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
364 6 2 5 4.7 CCCCC(=O)NC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3718612 rxfp1_human Human No 5.2 EC50 = 5930 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
367 4 2 4 4.4 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)[N+](=O)[O-]
CHEMBL3718178 rxfp1_human Human No 5.2 EC50 = 5930 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
385 4 2 6 4.0 C1=CC=C(C(=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC(=O)C3=CN=CC=C3
CHEMBL3715266 rxfp1_human Human No 4.2 EC50 = 59300 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
338 6 2 6 4.0 COCCNC1=CC=CC=C1C(=O)NC2=CC=CC(=C2)C(F)(F)F
CHEMBL3718400 rxfp1_human Human No 7.2 EC50 = 67 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
546 7 2 11 5.7 C1=CC=C(C(=C1)C(=O)NC2=CC(=CC=C2)S(=O)(=O)C(F)(F)F)NC(=O)C3=CC=CC=C3OCC(F)(F)F
CHEMBL3716540 rxfp1_human Human No 6.1 EC50 = 747 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
458 8 2 7 4.9 COCCOC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715743 rxfp1_human Human No 6.1 EC50 = 747 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
493 7 2 9 3.9 CCOC1=CC=CC=C1C(=O)NC2=C(C=NC=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3716581 rxfp1_human Human No 5.1 EC50 = 7470 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
444 6 2 7 5.0 COC1=C(C(=CC=C1)OC)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3715001 rxfp1_human Human No 5.1 EC50 = 8380 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
398 5 2 5 5.0 C1=CC=C(C=C1)CC(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3718643 rxfp1_human Human No 5.1 EC50 = 8380 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
348 4 2 5 3.8 C1CC1C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL3716980 rxfp1_human Human Yes 7.0 EC50 = 94 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
507 7 2 8 5.4 CC(C)OC1=CC=CC=C1C(=O)NC2=CC=CC=C2C(=O)NC3=CC(=CC=C3)S(=O)(=O)C(F)(F)F
CHEMBL3717718 rxfp1_human Human No 5.0 EC50 = 9400 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
446 7 3 4 5.0 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=C3C(=O)NCC4=CC=CO4
CHEMBL3718813 rxfp1_human Human Yes 5.0 EC50 = 9400 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
414 5 2 6 5.0 COC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(F)(F)F
CHEMBL1491180 rxfp1_human Human Yes 4.0 EC50 = 94000 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
322 4 2 2 4.6 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC=C3
CHEMBL3717485 rxfp1_human Human No 4.0 EC50 = 94000 Funct
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
390 4 2 5 5.5 C1CCC(CC1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC=C(C=C3)C(F)(F)F
CHEMBL28449 rxfp1_human Human Yes 6.0 Potency = 1000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
320 3 4 8 -0.5 C1CC1NC(=O)C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)O
CHEMBL28449 rxfp1_human Human Yes 6.0 Potency = 1000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
320 3 4 8 -0.5 C1CC1NC(=O)C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)O
CHEMBL1426572 rxfp1_human Human No 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 4 4 4 5.5 CC1=C(C=C(C=C1)NC(=S)NC(=O)C2=CC=CC=C2)NC(=S)NC(=O)C3=CC=CC=C3
CHEMBL1509228 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
378 3 1 4 4.4 C1=CC=NC(=C1)C2=NC3=C(C=CC=C3Cl)C(=C2)C(=O)NC4=CC=C(C=C4)F
CHEMBL1611899 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
409 4 1 9 0.3 CN1C(=O)C(=NNC2=CC(=CC=C2)S(=O)(=O)N3CCOCC3)C(=O)N(C1=O)C
CHEMBL1502018 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
382 8 4 8 2.9 C1=CC=C2C(=C1)C(=O)C3=C(C=CC(=C3C2=O)NCCC(=O)O)NCCC(=O)O
CHEMBL1489236 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
372 6 0 6 4.1 C1=CC=C(C(=C1)CON2C3=CC=CC=C3N=N2)CON4C5=CC=CC=C5N=N4
CHEMBL1592912 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
431 5 1 8 5.0 C1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)F)C(F)(F)F)C#N
CHEMBL1457270 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
473 4 1 4 6.2 COC1=CC=CC=C1C(=O)NC2=CC3=C(C=C2)OC(=N3)C4=CC=CC5=C4C=CC=C5Br
CHEMBL1495115 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
439 7 1 7 3.0 CC1=CSC2=NC(=CC(=O)N12)COC3=CC=C(C=C3)NC(=O)COC4=CC=C(C=C4)F
CHEMBL1576381 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
308 5 0 5 3.0 CC(=O)C1=CC(=C(C=C1)OC)COC2=NC=NC3=CC=CC=C32
CHEMBL1172596 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
439 5 1 8 3.9 C1=CC=C(C=C1)S(=O)(=O)C2=C3N=C(C4=C(N3N=N2)C=CS4)NCC5=CC=C(C=C5)F
CHEMBL1300691 rxfp1_human Human No 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
357 3 2 10 -1.7 CCOP1(=O)OCC2C(O1)C(C(O2)N3C=NC4=C3N=CN=C4N)O
CHEMBL1321879 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
288 2 3 7 0.6 C1C2=C(C=CC(=C2)NN=C3C(=O)NC(=O)NC3=O)C(=O)O1
CHEMBL1326901 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
224 2 1 4 2.5 CSC1=CC=CC=C1C2=NNC(=S)O2
CHEMBL1316197 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
477 8 1 8 2.8 COC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)C(=O)OCC3=CC(=O)N4C(=N3)SC(=N4)C5CC5
CHEMBL1369113 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
469 8 1 7 4.1 CC(C)CC(=O)NC1=CC=C(C=C1)C(=O)OCC2=CC(=O)N3C(=N2)SC(=N3)C4CCCCC4
CHEMBL1356009 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
386 5 2 6 1.0 CC1=CN2C(=NC=C(C2=O)C(=O)NCCC3=CC=C(C=C3)S(=O)(=O)N)C=C1
CHEMBL1356037 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
443 7 1 7 5.1 COC1=C(C=C(C=C1)CCNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC(=CC=C5)F)OC
CHEMBL1354031 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
377 4 1 6 3.6 COC1=C(C=C2C(=C1)C(=O)SC(=N2)NC(=O)C3=CC=C(C=C3)Cl)OC
CHEMBL1386021 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
446 6 2 4 2.5 CC1(C(=O)N(C(=O)N1)CC(=O)NCC2=CC=C(C=C2)OC)C3=CC(=CC=C3)Br
CHEMBL1379032 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
436 5 1 6 3.0 COC1=CC2=C(C=C1)N(C3=C2N=C4N(C3=O)CCS4)CC(=O)NC5=CC(=CC=C5)OC
CHEMBL1398407 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
370 4 1 4 4.5 CC1=C(C=CC=C1Cl)NC(=O)C2=CN=C(N=C2C3=CC=CC=C3)SC
CHEMBL1410062 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
302 5 0 6 3.1 CCOC(=O)CSC1=NC2=CC=CC=C2N3C1=NN=C3C
CHEMBL1400053 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
351 4 1 4 4.6 C1=CC=C(C=C1)CNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC=CC=C5
CHEMBL1388862 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
432 5 1 4 5.1 CC1=CC=C(C=C1)SC2=CC=C(C=C2)NC(=O)C3=C(C=C(C=C3)S(=O)(=O)C)Cl
CHEMBL1366864 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
429 4 1 6 4.9 CC1=C(C(=CC=C1)NC2=NC3=C(N=NN3C4=CC=CC=C42)S(=O)(=O)C5=CC=CC=C5)C
CHEMBL1410023 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
332 5 1 2 3.5 CC1=CC=C(C=C1)NC(=O)CN2C=C(C3=CC=CC=C32)C(=O)C4CC4
CHEMBL1461369 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
381 6 1 6 3.8 CCCCNC1=NC2=C(N=NN2C3=CC=CC=C31)S(=O)(=O)C4=CC=CC=C4
CHEMBL1473447 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
454 5 1 8 5.2 C1=CC(=CC(=C1)Cl)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=CS3)C(F)(F)F)C#N
CHEMBL1512435 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
368 8 1 7 2.2 CCCCC(=O)NC1=NN=C(S1)S(=O)(=O)N(C)CC2=CC=CC=C2
CHEMBL1513838 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
371 4 1 6 1.7 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCC(=O)NC4=CC=C(C=C4)F
CHEMBL1516149 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 4 2 4 6.9 CC1=C(C=C(C=C1)NC(=O)C2=C(C3=C(S2)N=C(C=C3C)C)NC(=O)C4=CC=CC=C4Cl)C
CHEMBL1572204 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
292 3 2 4 2.6 CC1=NN=C(C2=CC=CC=C12)NC3=CC=C(C=C3)C(=O)NC
CHEMBL1553067 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
442 5 1 7 4.6 CCC1=CC=C(C=C1)CNC(=O)C2CCN(CC2)C3=NC4=CC=CC=C4N=C3C(F)(F)F
CHEMBL1560108 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
376 3 2 4 2.6 C1C(CC(=O)C2=C1NC(=O)C(=C2)C(=O)NC3=CC(=CC=C3)F)C4=CC=CC=C4
CHEMBL1590845 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
432 5 1 5 3.3 CC1=C(C=C(C=C1)NC(=O)CN2C3=C(C=CC=N3)C(=O)N(C2=O)CC4=CC=C(C=C4)F)C
CHEMBL1603009 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
551 6 1 7 5.2 CC1=C(C(=CC=C1)C)NC(=O)CSC2=NC=C3C(=N2)C4=C(C=C(C=C4)Cl)N(S3(=O)=O)CC5=CC=CC=C5
CHEMBL3191381 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
368 6 1 6 2.4 CC1=NN(C(=O)C1=C(C)NCCCN2C=CN=C2)C3=CC=C(C=C3)[N+](=O)[O-]
CHEMBL1426572 rxfp1_human Human No 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 4 4 4 5.5 CC1=C(C=C(C=C1)NC(=S)NC(=O)C2=CC=CC=C2)NC(=S)NC(=O)C3=CC=CC=C3
CHEMBL1509228 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
378 3 1 4 4.4 C1=CC=NC(=C1)C2=NC3=C(C=CC=C3Cl)C(=C2)C(=O)NC4=CC=C(C=C4)F
CHEMBL1611899 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
409 4 1 9 0.3 CN1C(=O)C(=NNC2=CC(=CC=C2)S(=O)(=O)N3CCOCC3)C(=O)N(C1=O)C
CHEMBL1502018 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
382 8 4 8 2.9 C1=CC=C2C(=C1)C(=O)C3=C(C=CC(=C3C2=O)NCCC(=O)O)NCCC(=O)O
CHEMBL1592912 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
431 5 1 8 5.0 C1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)F)C(F)(F)F)C#N
CHEMBL1457270 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
473 4 1 4 6.2 COC1=CC=CC=C1C(=O)NC2=CC3=C(C=C2)OC(=N3)C4=CC=CC5=C4C=CC=C5Br
CHEMBL1495115 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
439 7 1 7 3.0 CC1=CSC2=NC(=CC(=O)N12)COC3=CC=C(C=C3)NC(=O)COC4=CC=C(C=C4)F
CHEMBL1576381 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
308 5 0 5 3.0 CC(=O)C1=CC(=C(C=C1)OC)COC2=NC=NC3=CC=CC=C32
CHEMBL1172596 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
439 5 1 8 3.9 C1=CC=C(C=C1)S(=O)(=O)C2=C3N=C(C4=C(N3N=N2)C=CS4)NCC5=CC=C(C=C5)F
CHEMBL1300691 rxfp1_human Human No 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
357 3 2 10 -1.7 CCOP1(=O)OCC2C(O1)C(C(O2)N3C=NC4=C3N=CN=C4N)O
CHEMBL1321879 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
288 2 3 7 0.6 C1C2=C(C=CC(=C2)NN=C3C(=O)NC(=O)NC3=O)C(=O)O1
CHEMBL1326901 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
224 2 1 4 2.5 CSC1=CC=CC=C1C2=NNC(=S)O2
CHEMBL1316197 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
477 8 1 8 2.8 COC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)C(=O)OCC3=CC(=O)N4C(=N3)SC(=N4)C5CC5
CHEMBL1369113 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
469 8 1 7 4.1 CC(C)CC(=O)NC1=CC=C(C=C1)C(=O)OCC2=CC(=O)N3C(=N2)SC(=N3)C4CCCCC4
CHEMBL1356009 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
386 5 2 6 1.0 CC1=CN2C(=NC=C(C2=O)C(=O)NCCC3=CC=C(C=C3)S(=O)(=O)N)C=C1
CHEMBL1356037 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
443 7 1 7 5.1 COC1=C(C=C(C=C1)CCNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC(=CC=C5)F)OC
CHEMBL1354031 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
377 4 1 6 3.6 COC1=C(C=C2C(=C1)C(=O)SC(=N2)NC(=O)C3=CC=C(C=C3)Cl)OC
CHEMBL1386021 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
446 6 2 4 2.5 CC1(C(=O)N(C(=O)N1)CC(=O)NCC2=CC=C(C=C2)OC)C3=CC(=CC=C3)Br
CHEMBL1379032 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
436 5 1 6 3.0 COC1=CC2=C(C=C1)N(C3=C2N=C4N(C3=O)CCS4)CC(=O)NC5=CC(=CC=C5)OC
CHEMBL1398407 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
370 4 1 4 4.5 CC1=C(C=CC=C1Cl)NC(=O)C2=CN=C(N=C2C3=CC=CC=C3)SC
CHEMBL1410062 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
302 5 0 6 3.1 CCOC(=O)CSC1=NC2=CC=CC=C2N3C1=NN=C3C
CHEMBL1400053 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
351 4 1 4 4.6 C1=CC=C(C=C1)CNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC=CC=C5
CHEMBL1388862 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
432 5 1 4 5.1 CC1=CC=C(C=C1)SC2=CC=C(C=C2)NC(=O)C3=C(C=C(C=C3)S(=O)(=O)C)Cl
CHEMBL1410023 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
332 5 1 2 3.5 CC1=CC=C(C=C1)NC(=O)CN2C=C(C3=CC=CC=C32)C(=O)C4CC4
CHEMBL1461369 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
381 6 1 6 3.8 CCCCNC1=NC2=C(N=NN2C3=CC=CC=C31)S(=O)(=O)C4=CC=CC=C4
CHEMBL1473447 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
454 5 1 8 5.2 C1=CC(=CC(=C1)Cl)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=CS3)C(F)(F)F)C#N
CHEMBL1512435 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
368 8 1 7 2.2 CCCCC(=O)NC1=NN=C(S1)S(=O)(=O)N(C)CC2=CC=CC=C2
CHEMBL1513838 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
371 4 1 6 1.7 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCC(=O)NC4=CC=C(C=C4)F
CHEMBL1516149 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 4 2 4 6.9 CC1=C(C=C(C=C1)NC(=O)C2=C(C3=C(S2)N=C(C=C3C)C)NC(=O)C4=CC=CC=C4Cl)C
CHEMBL1572204 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
292 3 2 4 2.6 CC1=NN=C(C2=CC=CC=C12)NC3=CC=C(C=C3)C(=O)NC
CHEMBL1553067 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
442 5 1 7 4.6 CCC1=CC=C(C=C1)CNC(=O)C2CCN(CC2)C3=NC4=CC=CC=C4N=C3C(F)(F)F
CHEMBL1560108 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
376 3 2 4 2.6 C1C(CC(=O)C2=C1NC(=O)C(=C2)C(=O)NC3=CC(=CC=C3)F)C4=CC=CC=C4
CHEMBL1590845 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
432 5 1 5 3.3 CC1=C(C=C(C=C1)NC(=O)CN2C3=C(C=CC=N3)C(=O)N(C2=O)CC4=CC=C(C=C4)F)C
CHEMBL1603009 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
551 6 1 7 5.2 CC1=C(C(=CC=C1)C)NC(=O)CSC2=NC=C3C(=N2)C4=C(C=C(C=C4)Cl)N(S3(=O)=O)CC5=CC=CC=C5
CHEMBL3191381 rxfp1_human Human Yes 5.0 Potency = 10000 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
368 6 1 6 2.4 CC1=NN(C(=O)C1=C(C)NCCCN2C=CN=C2)C3=CC=C(C=C3)[N+](=O)[O-]
CHEMBL1318270 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
450 6 0 4 5.7 C1=CC=C(C=C1)C(=O)CSC2=NN=C(N2C3=CC=CC=C3)C4=CC=C(C=C4)Br
CHEMBL1992883 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
349 2 1 6 2.5 CC1=CC=CC(=C1)C(=O)NN=C2CS(=O)(=O)N(C3=C2SC=C3)C
CHEMBL1417596 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
388 4 2 5 4.0 CC1=CC(=CC=C1)OCC(=O)NC2=CC(=O)C(=C3NC4=C(O3)C=CC(=C4)C)C=C2
CHEMBL1364442 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
384 6 1 7 0.7 COC1=CC=C(C=C1)N2C3=C(C(=O)N(C=N3)CC(=O)NCC4CCCO4)N=N2
CHEMBL1539280 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
463 5 1 6 5.9 C1C2CC3CC1CC(C2)(C3)C(=O)CSC4=C(C(=C(C(=N4)N)C#N)C5=CC=C(C=C5)Cl)C#N
CHEMBL1341012 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
435 4 1 6 5.1 CC1=CC(=NO1)N2C(C(=C(C2=O)O)C(=O)C3=CC4=CC=CC=C4O3)C5=CC(=CC=C5)Cl
CHEMBL1344527 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
233 3 1 4 3.0 CC(C(=O)O)SC1=NC2=CC=CC=C2C=C1
CHEMBL1349094 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
413 6 1 8 2.2 CN(CC1=CC=CO1)S(=O)(=O)C2=NN=C(S2)NC(=O)C3=CC=CC=C3Cl
CHEMBL1344120 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
345 4 0 6 2.0 C1CCN(C1)C(=O)CSC2=NN3C(=NN=C3C4=CC=CS4)C=C2
CHEMBL1330383 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
247 0 1 3 3.3 C1=CC=C2C(=C1)C3=CC(=C(C=C3OC2=O)O)Cl
CHEMBL1396454 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
387 4 1 6 4.8 C1=CC=C2C(=C1)C(=NC3=C(N=NN23)C4=CC=C(C=C4)F)NCC5=CC=C(C=C5)F
CHEMBL1383330 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
395 3 1 7 2.1 C1CC(=O)N(C1=O)C2=CC=C(C=C2)C(=O)NC3=NC4=CC5=C(C=C4S3)OCO5
CHEMBL1448461 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 10 0 8 2.2 CCN(CC)S(=O)(=O)C1=CC2=C(C=C1)N(C(=N2)CCC(=O)OCC3=C(ON=C3C)C)C
CHEMBL1466287 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
372 7 1 6 3.2 CCCCN1C(=O)C2=CC=CC=C2N=C1SCC(=O)NC3=NOC(=C3)C
CHEMBL1520822 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
489 6 1 7 3.9 C1=CC=C(C=C1)CN2C3=CC=CC=C3C4=NC(=NC=C4S2(=O)=O)SCC(=O)NC5=CC=CC=C5
CHEMBL1498535 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
485 7 2 7 1.5 CCN(CC)S(=O)(=O)C1=CC(=C(C=C1)N2CCOCC2)NC(=O)C3=CC(=O)NC4=CC=CC=C43
CHEMBL1532051 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
310 3 1 3 2.0 CC1=CC(=C(C=C1)NC(=O)CN2C(=O)C3=CC=CN3C(=N2)C)C
CHEMBL1572793 rxfp1_human Human No 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
218 4 2 2 2.8 CC(C)NC1=CC=C(C=C1)NC(=O)C(=C)C
CHEMBL1572639 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
340 4 1 4 1.5 CC1=NN(C(=O)C2=CC3=CC=CC=C3N12)CC(=O)NCC4CCCO4
CHEMBL1584231 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
428 7 1 8 2.9 C1C(=O)N(C(=O)S1)CCNC(=O)COC2=C3C(=CSC3=NC=N2)C4=CC=CC=C4
CHEMBL1591452 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
567 8 1 8 4.9 CCOC1=CC=C(C=C1)NC(=O)CSC2=NC=C3C(=N2)C4=C(C=C(C=C4)Cl)N(S3(=O)=O)CC5=CC=CC=C5
CHEMBL1590799 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 4 1 7 5.4 CC1=CC(=C(C=C1)C)S(=O)(=O)C2=C3N=C(C4=C(N3N=N2)C=CS4)NC5=CC(=C(C=C5)C)C
CHEMBL1611566 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 6 1 9 4.6 COC1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=CS3)C(F)(F)F)C#N
CHEMBL1318270 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
450 6 0 4 5.7 C1=CC=C(C=C1)C(=O)CSC2=NN=C(N2C3=CC=CC=C3)C4=CC=C(C=C4)Br
CHEMBL1992883 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
349 2 1 6 2.5 CC1=CC=CC(=C1)C(=O)NN=C2CS(=O)(=O)N(C3=C2SC=C3)C
CHEMBL1417596 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
388 4 2 5 4.0 CC1=CC(=CC=C1)OCC(=O)NC2=CC(=O)C(=C3NC4=C(O3)C=CC(=C4)C)C=C2
CHEMBL1364442 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
384 6 1 7 0.7 COC1=CC=C(C=C1)N2C3=C(C(=O)N(C=N3)CC(=O)NCC4CCCO4)N=N2
CHEMBL1341012 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
435 4 1 6 5.1 CC1=CC(=NO1)N2C(C(=C(C2=O)O)C(=O)C3=CC4=CC=CC=C4O3)C5=CC(=CC=C5)Cl
CHEMBL1344527 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
233 3 1 4 3.0 CC(C(=O)O)SC1=NC2=CC=CC=C2C=C1
CHEMBL1349094 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
413 6 1 8 2.2 CN(CC1=CC=CO1)S(=O)(=O)C2=NN=C(S2)NC(=O)C3=CC=CC=C3Cl
CHEMBL1344120 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
345 4 0 6 2.0 C1CCN(C1)C(=O)CSC2=NN3C(=NN=C3C4=CC=CS4)C=C2
CHEMBL1330383 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
247 0 1 3 3.3 C1=CC=C2C(=C1)C3=CC(=C(C=C3OC2=O)O)Cl
CHEMBL1396454 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
387 4 1 6 4.8 C1=CC=C2C(=C1)C(=NC3=C(N=NN23)C4=CC=C(C=C4)F)NCC5=CC=C(C=C5)F
CHEMBL1383330 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
395 3 1 7 2.1 C1CC(=O)N(C1=O)C2=CC=C(C=C2)C(=O)NC3=NC4=CC5=C(C=C4S3)OCO5
CHEMBL1448461 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 10 0 8 2.2 CCN(CC)S(=O)(=O)C1=CC2=C(C=C1)N(C(=N2)CCC(=O)OCC3=C(ON=C3C)C)C
CHEMBL1466287 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
372 7 1 6 3.2 CCCCN1C(=O)C2=CC=CC=C2N=C1SCC(=O)NC3=NOC(=C3)C
CHEMBL1520822 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
489 6 1 7 3.9 C1=CC=C(C=C1)CN2C3=CC=CC=C3C4=NC(=NC=C4S2(=O)=O)SCC(=O)NC5=CC=CC=C5
CHEMBL1498535 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
485 7 2 7 1.5 CCN(CC)S(=O)(=O)C1=CC(=C(C=C1)N2CCOCC2)NC(=O)C3=CC(=O)NC4=CC=CC=C43
CHEMBL1532051 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
310 3 1 3 2.0 CC1=CC(=C(C=C1)NC(=O)CN2C(=O)C3=CC=CN3C(=N2)C)C
CHEMBL1572793 rxfp1_human Human No 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
218 4 2 2 2.8 CC(C)NC1=CC=C(C=C1)NC(=O)C(=C)C
CHEMBL1572639 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
340 4 1 4 1.5 CC1=NN(C(=O)C2=CC3=CC=CC=C3N12)CC(=O)NCC4CCCO4
CHEMBL1584231 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
428 7 1 8 2.9 C1C(=O)N(C(=O)S1)CCNC(=O)COC2=C3C(=CSC3=NC=N2)C4=CC=CC=C4
CHEMBL1591452 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
567 8 1 8 4.9 CCOC1=CC=C(C=C1)NC(=O)CSC2=NC=C3C(=N2)C4=C(C=C(C=C4)Cl)N(S3(=O)=O)CC5=CC=CC=C5
CHEMBL1590799 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 4 1 7 5.4 CC1=CC(=C(C=C1)C)S(=O)(=O)C2=C3N=C(C4=C(N3N=N2)C=CS4)NC5=CC(=C(C=C5)C)C
CHEMBL1611566 rxfp1_human Human Yes 5.0 Potency = 11220.2 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 6 1 9 4.6 COC1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=CS3)C(F)(F)F)C#N
CHEMBL1388847 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
397 6 1 6 2.0 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NC4=CC=CC=C4OC
CHEMBL1510719 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
437 7 1 7 2.1 COC1=C(C=C(C=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)S(=O)(=O)NCC4=CC=CC=C4
CHEMBL1327902 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
316 3 1 6 4.2 CC1=C(SC2=C1C(=NC=N2)SC3=CC=CC=C3C(=O)O)C
CHEMBL1417926 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
460 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC=C(S3)Br
CHEMBL1432350 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
314 4 1 6 0.8 CN1C(=C(C(=O)N(C1=O)C)C(=O)COC2=CC=C(C=C2)C#N)N
CHEMBL1386075 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
312 4 0 5 0.7 CC(=O)C1=CC(=C(C=C1)OC)CN2C=NC3=C(C2=O)C=NN3C
CHEMBL1499911 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
378 4 0 3 4.4 COC1=CC=C(C=C1)N2C3=C(CCCC3)C(=S)N=C2C4=CC(=CC=C4)OC
CHEMBL1301594 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
415 5 0 7 1.6 COC1=C(C=C(C=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)S(=O)(=O)N4CCCCC4
CHEMBL358644 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
221 0 2 5 0.8 C1=CC(=O)C=C2C1=CC(=C(N)S)C(=O)O2
CHEMBL1514065 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
492 5 1 3 5.8 CC1=CC2=CC=CC=C2N1C3=CC=C(S3)C(=O)N4CCC(CC4)C(=O)NCC5=CC=CC=C5Cl
CHEMBL1381650 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
353 5 1 5 3.7 CC1=CC=CC2=C1N=C(C(=C2)C#N)SCC(=O)NCC3=CC=CS3
CHEMBL1434956 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
445 6 1 5 5.2 CC1=C(SC(=N1)N2C(=C(C(=N2)C)CC3=CC=CC=C3)C)C(=O)NC4=CC=C(C=C4)C(=O)C
CHEMBL1305078 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
397 4 1 7 2.2 CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N3C(=O)C4=CC=CC=C4C3=O
CHEMBL1363060 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
250 1 2 6 1.5 CC1(CC2=C(CO1)SC3=NC=NC(=C23)NN)C
CHEMBL1336927 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
337 2 0 6 2.8 C1=COC(=C1)C2=NN=C3N2N=C(S3)C4=CC=C(O4)Br
CHEMBL1336606 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
361 2 0 3 4.3 CCN1C(=C2C(=O)N(C(=S)N2C3=CC=CC=C3)C)C=CC4=CC=CC=C41
CHEMBL1327484 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
254 3 1 4 3.0 C1=CC2=C(C=CN=C2C=C1Cl)SCC(=O)O
CHEMBL1362040 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
418 5 2 5 4.0 CCOC(=O)C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)SC4=CC=CC=C4C(=O)N3
CHEMBL1393131 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
318 2 1 4 3.2 C1=COC(=C1)C2=NC3=C(C=C(C=C3)Br)C(=C2)C(=O)O
CHEMBL1422972 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
382 6 1 6 0.9 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NCC4=CN=CC=C4
CHEMBL1389475 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
444 6 1 9 4.0 CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CC=CS3)C4=NC(=C(S4)C(=O)OC)C)O
CHEMBL1438931 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
445 5 1 8 5.3 CC1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)F)C(F)(F)F)C#N
CHEMBL1433636 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
457 3 1 3 6.6 CC1=CC=CC(=C1)C(=O)NC2=CC3=C(C=C2)OC(=N3)C4=CC=CC5=C4C=CC=C5Br
CHEMBL1474011 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 5 2 4 6.9 CCC1=CC=C(C=C1)NC(=O)C2=C(C3=C(C(=C(N=C3S2)C)Cl)C)NC(=O)C4=CC=CC=C4
CHEMBL1474423 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
370 4 2 5 -0.3 CC(=O)NC1=CC(=CC=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C
CHEMBL1466770 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
373 5 1 7 3.9 CCC1=C(N=C2C=C3C(=CC2=C1)OCO3)SCC(=O)NC4=NC=CS4
CHEMBL1485560 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
383 4 1 7 2.0 CC1=NN2C(=NN=C2C3=C(C=CC(=C3)S(=O)(=O)NC)OC)C4=CC=CC=C14
CHEMBL1506287 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
453 7 1 7 1.7 CCN(CC)S(=O)(=O)C1=CC2=C(C=C1)OCC(=O)N2CC(=O)NC3=C(N=CC=C3)Cl
CHEMBL1515965 rxfp1_human Human No 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 6 1 6 4.5 CC1=NC2=C(C=C1)C(=O)C(=CN2CC(=O)NCC3=CC=C(C=C3)F)C(=O)C4=CC(=CC=C4)Cl
CHEMBL1525727 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 3 0 8 2.9 CN1CCN(CC1)C2=NC3=C(N=NN3C4=C2SC=C4)S(=O)(=O)C5=CC=C(C=C5)Cl
CHEMBL1500673 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
381 5 2 3 2.9 CC1=CC2=C(C=C1)NC(=O)C(=C2)CN(CC3=CC=C(C=C3)OC)C(=S)NC
CHEMBL1492743 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
475 4 1 7 3.8 CC1=CC(=C(C=C1)C)NC(=O)CSC2=NC=C3C(=N2)C4=C(C=C(C=C4)Cl)N(S3(=O)=O)C
CHEMBL1528709 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
460 5 1 5 4.4 CC1=C(C=C(C=C1)NC(=O)CN2C3=C(C(=O)N(C2=O)CC4=CC=CO4)SC5=CC=CC=C53)C
CHEMBL1537195 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
248 4 1 5 2.3 CC1=NC2=CC=CC=C2C(=N1)SCCC(=O)O
CHEMBL1546597 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
361 7 0 6 1.1 COCCN(CCOC)C(=O)C1=CC2=C(S1)N=C3C=CC=CN3C2=O
CHEMBL1590310 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
453 7 1 6 6.1 CC1=C(SC2=NC=NC(=C12)N(C)C3CCCCC3)C(=O)NCC4=CC=C(C=C4)OC(C)C
CHEMBL1592455 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 5 1 4 3.8 CC1=C(C(=CC=C1)C)NC(=O)CN2C3=C(C=CC=N3)C(=O)N(C2=O)CC4=CC=CC=C4Cl
CHEMBL1565042 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
367 6 1 4 2.4 C1=CC=C(C=C1)CCNC(=O)CN2C=CN(C(=O)C2=O)C3=CC=C(C=C3)F
CHEMBL1543276 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
323 2 1 5 3.7 C1=CC(=CC=C1C(=O)NC2=NC3=C(C(=O)S2)SC=C3)Cl
CHEMBL1587934 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
427 8 1 5 3.5 CN(CC(=O)NC1=CC=CC=C1Cl)C(=O)COC(=O)CC2=C(C=CC=C2Cl)F
CHEMBL1601668 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
314 1 1 3 3.9 CC1=CC=C(C=C1)N2C(=O)C3=C(NC2=S)SC4=C3CCC4
CHEMBL1595812 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
436 7 1 7 2.0 CC(C)(C)CC1=NC2=C(C(=N1)SCC(=O)NCC3CCCO3)C(=O)N(C(=O)N2C)C
CHEMBL1604975 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
306 3 1 4 3.2 C=CCN1C(=O)C2=C(NC1=S)SC=C2C3=CC=CS3
CHEMBL65 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
348 1 1 5 1.0 CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
CHEMBL1510719 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
437 7 1 7 2.1 COC1=C(C=C(C=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)S(=O)(=O)NCC4=CC=CC=C4
CHEMBL1327902 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
316 3 1 6 4.2 CC1=C(SC2=C1C(=NC=N2)SC3=CC=CC=C3C(=O)O)C
CHEMBL1417926 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
460 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC=C(S3)Br
CHEMBL1432350 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
314 4 1 6 0.8 CN1C(=C(C(=O)N(C1=O)C)C(=O)COC2=CC=C(C=C2)C#N)N
CHEMBL1386075 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
312 4 0 5 0.7 CC(=O)C1=CC(=C(C=C1)OC)CN2C=NC3=C(C2=O)C=NN3C
CHEMBL1499911 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
378 4 0 3 4.4 COC1=CC=C(C=C1)N2C3=C(CCCC3)C(=S)N=C2C4=CC(=CC=C4)OC
CHEMBL1301594 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
415 5 0 7 1.6 COC1=C(C=C(C=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)S(=O)(=O)N4CCCCC4
CHEMBL358644 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
221 0 2 5 0.8 C1=CC(=O)C=C2C1=CC(=C(N)S)C(=O)O2
CHEMBL1514065 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
492 5 1 3 5.8 CC1=CC2=CC=CC=C2N1C3=CC=C(S3)C(=O)N4CCC(CC4)C(=O)NCC5=CC=CC=C5Cl
CHEMBL1381650 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
353 5 1 5 3.7 CC1=CC=CC2=C1N=C(C(=C2)C#N)SCC(=O)NCC3=CC=CS3
CHEMBL1434956 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
445 6 1 5 5.2 CC1=C(SC(=N1)N2C(=C(C(=N2)C)CC3=CC=CC=C3)C)C(=O)NC4=CC=C(C=C4)C(=O)C
CHEMBL1305078 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
397 4 1 7 2.2 CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N3C(=O)C4=CC=CC=C4C3=O
CHEMBL1363060 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
250 1 2 6 1.5 CC1(CC2=C(CO1)SC3=NC=NC(=C23)NN)C
CHEMBL1336927 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
337 2 0 6 2.8 C1=COC(=C1)C2=NN=C3N2N=C(S3)C4=CC=C(O4)Br
CHEMBL1336606 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
361 2 0 3 4.3 CCN1C(=C2C(=O)N(C(=S)N2C3=CC=CC=C3)C)C=CC4=CC=CC=C41
CHEMBL1327484 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
254 3 1 4 3.0 C1=CC2=C(C=CN=C2C=C1Cl)SCC(=O)O
CHEMBL1362040 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
418 5 2 5 4.0 CCOC(=O)C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)SC4=CC=CC=C4C(=O)N3
CHEMBL1393131 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
318 2 1 4 3.2 C1=COC(=C1)C2=NC3=C(C=C(C=C3)Br)C(=C2)C(=O)O
CHEMBL1422972 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
382 6 1 6 0.9 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NCC4=CN=CC=C4
CHEMBL1389475 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
444 6 1 9 4.0 CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CC=CS3)C4=NC(=C(S4)C(=O)OC)C)O
CHEMBL1438931 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
445 5 1 8 5.3 CC1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)F)C(F)(F)F)C#N
CHEMBL1433636 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
457 3 1 3 6.6 CC1=CC=CC(=C1)C(=O)NC2=CC3=C(C=C2)OC(=N3)C4=CC=CC5=C4C=CC=C5Br
CHEMBL1474011 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 5 2 4 6.9 CCC1=CC=C(C=C1)NC(=O)C2=C(C3=C(C(=C(N=C3S2)C)Cl)C)NC(=O)C4=CC=CC=C4
CHEMBL1474423 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
370 4 2 5 -0.3 CC(=O)NC1=CC(=CC=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C
CHEMBL1466770 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
373 5 1 7 3.9 CCC1=C(N=C2C=C3C(=CC2=C1)OCO3)SCC(=O)NC4=NC=CS4
CHEMBL1485560 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
383 4 1 7 2.0 CC1=NN2C(=NN=C2C3=C(C=CC(=C3)S(=O)(=O)NC)OC)C4=CC=CC=C14
CHEMBL1506287 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
453 7 1 7 1.7 CCN(CC)S(=O)(=O)C1=CC2=C(C=C1)OCC(=O)N2CC(=O)NC3=C(N=CC=C3)Cl
CHEMBL1515965 rxfp1_human Human No 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
464 6 1 6 4.5 CC1=NC2=C(C=C1)C(=O)C(=CN2CC(=O)NCC3=CC=C(C=C3)F)C(=O)C4=CC(=CC=C4)Cl
CHEMBL1525727 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 3 0 8 2.9 CN1CCN(CC1)C2=NC3=C(N=NN3C4=C2SC=C4)S(=O)(=O)C5=CC=C(C=C5)Cl
CHEMBL1492743 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
475 4 1 7 3.8 CC1=CC(=C(C=C1)C)NC(=O)CSC2=NC=C3C(=N2)C4=C(C=C(C=C4)Cl)N(S3(=O)=O)C
CHEMBL1528709 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
460 5 1 5 4.4 CC1=C(C=C(C=C1)NC(=O)CN2C3=C(C(=O)N(C2=O)CC4=CC=CO4)SC5=CC=CC=C53)C
CHEMBL1537195 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
248 4 1 5 2.3 CC1=NC2=CC=CC=C2C(=N1)SCCC(=O)O
CHEMBL1546597 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
361 7 0 6 1.1 COCCN(CCOC)C(=O)C1=CC2=C(S1)N=C3C=CC=CN3C2=O
CHEMBL1590310 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
453 7 1 6 6.1 CC1=C(SC2=NC=NC(=C12)N(C)C3CCCCC3)C(=O)NCC4=CC=C(C=C4)OC(C)C
CHEMBL1592455 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
449 5 1 4 3.8 CC1=C(C(=CC=C1)C)NC(=O)CN2C3=C(C=CC=N3)C(=O)N(C2=O)CC4=CC=CC=C4Cl
CHEMBL1565042 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
367 6 1 4 2.4 C1=CC=C(C=C1)CCNC(=O)CN2C=CN(C(=O)C2=O)C3=CC=C(C=C3)F
CHEMBL1543276 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
323 2 1 5 3.7 C1=CC(=CC=C1C(=O)NC2=NC3=C(C(=O)S2)SC=C3)Cl
CHEMBL1587934 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
427 8 1 5 3.5 CN(CC(=O)NC1=CC=CC=C1Cl)C(=O)COC(=O)CC2=C(C=CC=C2Cl)F
CHEMBL1601668 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
314 1 1 3 3.9 CC1=CC=C(C=C1)N2C(=O)C3=C(NC2=S)SC4=C3CCC4
CHEMBL1595812 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
436 7 1 7 2.0 CC(C)(C)CC1=NC2=C(C(=N1)SCC(=O)NCC3CCCO3)C(=O)N(C(=O)N2C)C
CHEMBL1604975 rxfp1_human Human Yes 4.9 Potency = 12589.3 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
306 3 1 4 3.2 C=CCN1C(=O)C2=C(NC1=S)SC=C2C3=CC=CS3
CHEMBL1512545 rxfp1_human Human Yes 5.9 Potency = 1412.5 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
577 11 7 11 0.2 C1=CC(=CC=C1CC(=O)NC2=CC=C(C=C2)CC(=O)NCCN)NC3=NC=NC4=C3N=CN4C5C(C(C(O5)CO)O)O
CHEMBL1512545 rxfp1_human Human Yes 5.9 Potency = 1412.5 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
577 11 7 11 0.2 C1=CC(=CC=C1CC(=O)NC2=CC=C(C=C2)CC(=O)NCCN)NC3=NC=NC4=C3N=CN4C5C(C(C(O5)CO)O)O
CHEMBL1368980 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
316 3 1 4 2.8 COC1=CC=CC=C1CN2C(=O)C3=C(C=CC(=C3)F)NC2=S
CHEMBL1580853 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
481 8 1 8 5.0 CCCOC1=CC=CC(=C1)C2C(=C(C(=O)N2C3=NC(=C(S3)C(=O)C)C)O)C(=O)C4=CC=C(O4)C
CHEMBL1387110 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
409 3 2 7 5.4 C1=CC=C2C(=C1)N=C(S2)NC(=O)C3=C(C4=C(S3)N=C(C=C4)C5=CC=CS5)N
CHEMBL1544280 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
370 6 1 7 1.0 C1CC(OC1)CNC(=O)CSC2=NN=C3N2N=C(C=C3)C4=CC=CC=N4
CHEMBL1375543 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
475 5 0 7 1.0 CC(C)N1C2=C(N=C1SCC(=O)N3CCN(CC3)C(=O)C4=CC=CO4)N(C(=O)N(C2=O)C)C
CHEMBL1468056 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
391 6 1 5 1.6 CC1=C(SC2=C1C(=O)N(C=N2)CC(=O)NCCCC(=O)N3CCCCC3)C
CHEMBL1420938 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
431 4 1 4 4.3 CC1=C2C(=CC(=C1)Br)C(=CC(=N2)C3=CC=CS3)C(=O)NCC4CCCO4
CHEMBL1449453 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
429 5 1 5 5.9 CC1=C(SC2=NC=NC(=C12)N(C)C3CCCCC3)C(=O)NCC4=CC=CC=C4Cl
CHEMBL1448105 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
247 1 1 3 4.1 C1=CC2=C(C=C1Cl)SC(=C2Cl)C(=O)O
CHEMBL1385074 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
400 5 1 6 3.3 C1=CC=C2C(=C1)C=C(O2)C(=O)C3=C(C(=O)N(C3C4=CN=CC=C4)CC5=CC=CO5)O
CHEMBL1519696 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
457 6 1 7 3.6 CC1=C(C=C(C=C1)S(=O)(=O)N2CCCCC2)NC(=O)CSC3=NC=NC4=CC=CC=C43
CHEMBL1367087 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
419 7 1 4 4.4 CCOCCCNC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC=C(S3)Br
CHEMBL1356206 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
439 7 1 6 5.6 CCOC1=CC=C(C=C1)CNC(=O)C2=C(C3=C(N=CN=C3S2)N(C)C4CCCCC4)C
CHEMBL1607085 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
356 5 1 5 3.5 CC1=CC2=CC=CC=C2N3C1=NN=C3SCC(=O)NCC4CCCO4
CHEMBL1301318 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
444 8 2 9 1.8 COC1=CC(=C(C=C1C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CC=N3)OC)OC
CHEMBL1440872 rxfp1_human Human No 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
349 4 3 6 1.0 CNC(=O)NC(=O)CSC1=NC(=O)C(=C(N1)C2=CC=CS2)C#N
CHEMBL1593224 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
394 2 0 5 4.3 C1CN(CCN1C2=CC=CC=C2F)C(=O)C3=CC4=C(S3)C5=CC=CC=C5OC4
CHEMBL1375857 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
327 4 1 5 1.4 C1CC(OC1)CNC(=O)CN2C=NC3=C(C2=O)OC4=CC=CC=C43
CHEMBL1378340 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
421 4 1 5 4.4 COC1=CC=C(C=C1)C(=C2C(N(C(=O)C2=O)C3=CC=CC=N3)C4=CC(=CC=C4)Cl)O
CHEMBL1500596 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
474 7 1 6 3.6 CCN1C2=CC=CC=C2C3(C1=O)C(=C(C(=O)N3CCCN(C)C)O)C(=O)C4=CC5=CC=CC=C5O4
CHEMBL1591154 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
483 6 1 5 5.3 COC1=CC(=C(C=C1)CNC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=C(S4)Br)OC
CHEMBL1367765 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
410 10 1 8 4.5 CCCCOC(=O)CSC1=C(C(=C(C(=N1)N)C#N)C2=CC=C(C=C2)OCC)C#N
CHEMBL1302034 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
346 8 1 5 3.8 CCC1=C(N=C2C(=CC=CC2=C1)C)SCC(=O)NCC(=O)OCC
CHEMBL1513016 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
444 5 1 3 4.6 CCOC1=CC=CC=C1NC(=O)C2=CN(C(=O)C3=C2C4=CC=CC=C4N3C)C5CCCCC5
CHEMBL1397347 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
391 6 1 3 3.3 CC1=CC(=CC=C1)CNC(=O)CCCN2C3=C(C=CC(=C3)F)N4C=CC=C4C2=O
CHEMBL1534658 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
441 6 1 6 5.8 CC1=C(SC2=NC=NC(=C12)N(C)C3CCCCC3)C(=O)NCC4=CC=C(C=C4)SC
CHEMBL1413946 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
255 3 0 5 2.6 C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)SCCC#N
CHEMBL11909 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
267 2 4 8 -1.1 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O
CHEMBL1318769 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
479 8 2 5 5.3 COC1=C(C=C(C=C1)C2=NC3=NNC(=C3C(=C2)C(=O)NCCC4=CC=CC=C4)C5=CC=CC=C5)OC
CHEMBL1315511 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
462 8 2 6 5.7 CCOC1=C(C=C(C=C1)C(=O)NC2=C(OC3=CC=CC=C32)C(=O)NC4=CC=CC=C4F)OCC
CHEMBL1348101 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
309 4 1 4 3.9 CC1=CC=C(C=C1)C(=O)NC2=NN=C(S2)CC3=CC=CC=C3
CHEMBL1358814 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
332 4 1 5 5.2 CC1=CC(=CC=C1)NC2=NC(=NC(=C2C#N)C3=CC=CC=C3)SC
CHEMBL1368416 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
414 6 1 8 1.0 C1=CC2=NC(=CC(=O)N2C=C1)CSC3=NC4=C(C(=O)N3CCC(=O)O)SC=C4
CHEMBL1340736 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
359 4 2 6 3.3 C1=CC=C2C(=C1)C=CC(=C2S(=O)(=O)N)SC3=CC=CC=C3C(=O)O
CHEMBL1333441 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
504 4 1 5 4.3 C1CN(CC[NH+]1C2=NC3=C(C=C(C=C3)Br)C(=N2)C4=CC=CC=C4Cl)C(=O)CCC(=O)[O-]
CHEMBL1322400 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
407 4 2 6 5.3 CC1=C(C=C(C=C1)NC(=O)C2=C(C3=C(S2)N=C(C=C3)C4=CC(=CC=C4)OC)N)F
CHEMBL1335235 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
403 5 1 7 2.2 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NC4=CC(=C(C=C4)F)F
CHEMBL1318189 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
493 3 0 8 3.0 CN1CCN(CC1)C2=NC3=C(N=NN3C4=C2SC=C4)S(=O)(=O)C5=CC=C(C=C5)Br
CHEMBL1315996 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
381 5 1 5 4.6 COC1=CC=CC(=C1)CNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC=CC=C5
CHEMBL1318506 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
325 2 1 6 1.8 CC1=CC(=NC2=NC(=NN12)C(=O)NC3=CC4=C(C=C3)OCCO4)C
CHEMBL1318320 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
346 3 0 5 3.3 C1=CC=C(C=C1)N2C=CN(C(=O)C2=O)CC3=CC(=CC=C3)C(F)(F)F
CHEMBL1396136 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
344 3 0 4 5.1 CC1=CC2=C(O1)C=C3N2C(=NN=C3SCC4=CC=C(C=C4)Cl)C
CHEMBL1390399 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
296 3 1 4 4.5 CC1=C(SC2=CC=CC=C12)C(=O)C3=CC=CC=C3C(=O)O
CHEMBL1408014 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
367 5 1 5 1.2 C1COCCN1CCNC(=O)CN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O
CHEMBL1356105 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
456 8 1 6 4.6 C1=CC=C(C=C1)N2C(=NN=N2)SCCNCC3=CC=C(O3)C4=CC=C(C=C4)Br
CHEMBL1384046 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
427 6 0 8 0.7 CCOC(=O)N1CCN(CC1)C(=O)CSC2=NN3C(=NN=C3C4=CN=CC=C4)C=C2
CHEMBL1355268 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
409 5 1 5 5.7 CC1=CC(=CC=C1)CNC(=O)C2=C(C3=C(N=CN=C3S2)N(C)C4CCCCC4)C
CHEMBL1398397 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
312 1 1 3 3.8 CC1=CC=C(C=C1)N2C(=O)C3=C(NC2=O)SC4=C3CCCC4
CHEMBL1384448 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
432 7 1 4 4.6 CCN(CC)CCNC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC=C(S3)Br
CHEMBL1364957 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
395 6 1 6 4.7 CCOC1=CC=C(C=C1)NC(=O)CSC2=NC=NC3=C2SC4=CC=CC=C43
CHEMBL1413736 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
423 7 1 8 3.7 CC1=NN=C(S1)N2C(C(=C(C2=O)O)C(=O)C3=CC=CO3)C4=CC=C(C=C4)OCC=C
CHEMBL1357046 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
401 4 1 5 4.9 CC1=CC2=C(O1)C=C3N2C(=NN=C3SCC(=O)NC4=C(C(=CC=C4)Cl)C)C
CHEMBL1397047 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
516 12 1 6 6.4 CCOC1=C(C=C(C=C1)CCNC(=O)CSC2=NC3=CC=CC=C3N=C2CC4=CC=C(C=C4)C)OCC
CHEMBL1397611 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
432 6 2 4 6.3 CC1=CC=C(C=C1)OCC(=O)NC2=CC3=C(C=C2)N=C(C=C3C)NC4=CC(=CC=C4)Cl
CHEMBL1467713 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
401 6 2 7 2.5 CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3OC
CHEMBL1418824 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
400 4 0 8 0.3 CCOC(=O)N1CCN(CC1)S(=O)(=O)C2=C(N=C3N(C2=O)C(=CS3)C)C
CHEMBL1417116 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
249 2 1 4 1.5 CSC1=NC(=O)C(=C(N1)C2=CC=CS2)C#N
CHEMBL1423531 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
424 6 1 5 4.6 C1=CC=C(C=C1)CCN2C(C(=C(C2=O)O)C(=O)C3=CC4=CC=CC=C4O3)C5=CC=NC=C5
CHEMBL1429474 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
349 5 1 6 2.8 C1CC(OC1)CNC(=O)CSC2=NC=NC3=C2C4=C(S3)CCC4
CHEMBL1466048 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
467 8 1 8 2.1 COC1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)CN3C(=O)C4=C(C3=O)N=CC=C4)OC
CHEMBL1463377 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
425 4 1 3 4.6 CC1=C2C(=CC(=C1)Br)C(=CC(=N2)C3=CC=CC=C3)C(=O)NCC4CCCO4
CHEMBL1464025 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
335 5 0 5 4.1 CCOC(=O)C(=CC1=CC2=CC=CC=C2N=C1N3CCCCC3)C#N
CHEMBL1476377 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
472 6 1 5 4.5 COC1=CC=C(C=C1)NC(=O)CN2C3=C(C(=O)N(C2=O)CC4=CC=CC=C4)SC5=CC=CC=C53
CHEMBL1459809 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
290 3 1 4 2.6 C=CCN1C(=O)C2=C(NC1=S)SC=C2C3=CC=CO3
CHEMBL1416012 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
441 4 0 3 5.3 CC(C)C1=CC=C(C=C1)N2C(=O)N(C3=CC=CC=C3S2(=O)=O)CC4=CC=CC=C4Cl
CHEMBL1456558 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
398 7 1 7 1.7 CN(C)S(=O)(=O)C1=CC=C(C=C1)C(=O)OCC(=O)NC2=C(N=CC=C2)Cl
CHEMBL1422131 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
547 11 2 8 2.0 CCOC(=O)CCCCC(=O)C1=C(NC(=O)N1)CSC2=NC3=C(C4=C(N3C)C=CC(=C4)Br)N=N2
CHEMBL1435046 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
380 8 1 4 5.0 CC(C)CCNC(=O)CSC1=NC2=CC=CC=C2N=C1CC3=CC=CC=C3
CHEMBL1494680 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
369 4 1 5 4.7 C1=CC=C(C=C1)CNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC=C(C=C5)F
CHEMBL1525799 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
428 5 1 5 4.8 CCOC1=CC(=C(C=C1)C(=C2C(N(C(=O)C2=O)C3=CC=CC=N3)C4=CC=C(C=C4)C)O)C
CHEMBL1469191 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
510 10 2 8 1.5 COC1=C(C=C(C=C1)N2C(=O)C3=CC=CC=C3C(=N2)C(=O)NCC(=O)NCCCN4CCOCC4)OC
CHEMBL1491753 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
360 6 2 3 4.0 CC(C(=O)NC1=CC=C(C=C1)NC(=O)C2=CC=CC=C2)OC3=CC=CC=C3
CHEMBL1496411 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
277 2 3 7 1.0 C1=CC(=CC=C1NN=C2C(=O)NC(=O)NC2=O)[N+](=O)[O-]
CHEMBL1523965 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
487 5 1 11 5.5 C1=CC(=CC(=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=CS3)C(F)(F)F)C#N)C(F)(F)F
CHEMBL1525378 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
371 6 1 6 1.0 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NCC4=CC=CO4
CHEMBL1529358 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
405 5 2 3 6.2 CC(C)C1=CC=C(C=C1)OCC(=O)NC(=S)NC2=C3C=CC=C4C3=C(CC4)C=C2
CHEMBL1513368 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
503 8 1 10 5.2 CCOC(=O)C1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)F)C(F)(F)F)C#N
CHEMBL1505221 rxfp1_human Human No 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
452 4 1 8 3.9 CC1=NN(C2=C1C(=CC(=N2)C3=CC=C(C=C3)Br)C(F)(F)F)CCC4=NNN=N4
CHEMBL1526978 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
212 0 1 3 2.7 C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
CHEMBL1508887 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
396 2 1 4 3.9 C1=CC2=CC3=C(C=C2C(=C1)Br)C(=O)N(C3=O)C4=CC=CC(=C4)C(=O)O
CHEMBL1490578 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
315 5 1 7 1.7 CCC(C(=O)O)SC1=NN2C(=NN=C2C3=CN=CC=C3)C=C1
CHEMBL1531718 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
392 6 1 8 2.0 CC1=CC=CC(=C1)C(=O)NC2=NN=C(S2)S(=O)(=O)N(C)CC3=CC=CO3
CHEMBL1528897 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
333 3 2 6 0.9 CC1=C(C=CC=C1[N+](=O)[O-])C(=O)NNC2=CC(=O)N(C(=O)N2C)C
CHEMBL1592153 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
368 5 1 5 4.5 CCC1=CC(=CC=C1)NC(=O)CSC2=NN=CN3C2=CC4=C3C=CS4
CHEMBL1581437 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
430 5 1 7 4.4 CC1=CC(=NO1)N2C(C(=C(C2=O)O)C(=O)C3=CC4=CC=CC=C4O3)C5=CC=CC=C5OC
CHEMBL1583111 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
330 5 0 5 1.1 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCOC3=CC=C(C=C3)OC
CHEMBL1555399 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
423 6 1 5 6.1 CCC1=CC=C(C=C1)CNC(=O)C2=C(C3=C(N=CN=C3S2)N(C)C4CCCCC4)C
CHEMBL1530681 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
419 3 0 5 3.9 CC(=O)C1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(S3)C5=CC=CC=C5OC4
CHEMBL1533261 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
465 5 0 8 2.1 COC1=C(C=C(C=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)S(=O)(=O)N4CCOC5=CC=CC=C54
CHEMBL1565140 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
402 6 1 5 4.9 CC1=C(C=C(C=C1)OCC(=O)NC2=CC3=NN(N=C3C=C2)C4=CC=C(C=C4)OC)C
CHEMBL1525704 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
305 3 0 7 1.9 C1C2=CC(=CC(=C2OCO1)CSC3=NC=CC=N3)[N+](=O)[O-]
CHEMBL1562552 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
389 6 1 7 1.4 CC(C)NS(=O)(=O)C1=C(C=CC(=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)OC
CHEMBL1556192 rxfp1_human Human No 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
377 5 1 7 1.5 CC(C)NS(=O)(=O)C1=C(C=CC(=C1)F)CN2C(=O)C3=C(C2=O)N=CC=C3
CHEMBL1571921 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
460 9 1 4 5.7 CCCN(CCC)CCNC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC=C(S3)Br
CHEMBL1610070 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
423 6 1 7 3.1 CN(CC1=CC=CC=C1)S(=O)(=O)C2=NN=C(S2)NC(=O)C3=CC(=CC=C3)Cl
CHEMBL1598484 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
429 7 1 5 4.8 CCC1=CC=CC=C1NC(=O)COC2=CC3=C(C=C2)OC(=CC3=O)C4=CC=C(C=C4)OC
CHEMBL1604187 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
291 4 1 5 1.3 CC(=O)CSC1=NC(=O)C(=C(N1)C2=CC=CS2)C#N
CHEMBL1591352 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
454 6 1 5 5.3 CC1=CC=C(C=C1)C(=O)C2=CN(C3=C(C2=O)C=CC(=N3)C)CC(=O)NC4=CC=C(C=C4)C(C)C
CHEMBL1604935 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
329 6 0 7 2.0 CCC(C(=O)OC)SC1=NN2C(=NN=C2C3=CN=CC=C3)C=C1
CHEMBL1602197 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
383 4 1 5 4.8 CC1=CC(=C(C=C1)NC(=O)CSC2=NN=C(N3C2=CC4=C3C=CS4)C)C
CHEMBL1980641 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
424 5 2 8 0.8 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)NNC=C3C=NN=C3C4=CC=C(C=C4)F
CHEMBL1999641 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
377 4 1 5 3.4 CC1=C(N2C=CC=CC2=N1)C(=O)NN=C(C)C3=CC=C(C=C3)N4CCOCC4
CHEMBL1368980 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
316 3 1 4 2.8 COC1=CC=CC=C1CN2C(=O)C3=C(C=CC(=C3)F)NC2=S
CHEMBL1580853 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
481 8 1 8 5.0 CCCOC1=CC=CC(=C1)C2C(=C(C(=O)N2C3=NC(=C(S3)C(=O)C)C)O)C(=O)C4=CC=C(O4)C
CHEMBL1544280 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
370 6 1 7 1.0 C1CC(OC1)CNC(=O)CSC2=NN=C3N2N=C(C=C3)C4=CC=CC=N4
CHEMBL1375543 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
475 5 0 7 1.0 CC(C)N1C2=C(N=C1SCC(=O)N3CCN(CC3)C(=O)C4=CC=CO4)N(C(=O)N(C2=O)C)C
CHEMBL1468056 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
391 6 1 5 1.6 CC1=C(SC2=C1C(=O)N(C=N2)CC(=O)NCCCC(=O)N3CCCCC3)C
CHEMBL1420938 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
431 4 1 4 4.3 CC1=C2C(=CC(=C1)Br)C(=CC(=N2)C3=CC=CS3)C(=O)NCC4CCCO4
CHEMBL1449453 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
429 5 1 5 5.9 CC1=C(SC2=NC=NC(=C12)N(C)C3CCCCC3)C(=O)NCC4=CC=CC=C4Cl
CHEMBL1448105 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
247 1 1 3 4.1 C1=CC2=C(C=C1Cl)SC(=C2Cl)C(=O)O
CHEMBL1385074 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
400 5 1 6 3.3 C1=CC=C2C(=C1)C=C(O2)C(=O)C3=C(C(=O)N(C3C4=CN=CC=C4)CC5=CC=CO5)O
CHEMBL1519696 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
457 6 1 7 3.6 CC1=C(C=C(C=C1)S(=O)(=O)N2CCCCC2)NC(=O)CSC3=NC=NC4=CC=CC=C43
CHEMBL1367087 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
419 7 1 4 4.4 CCOCCCNC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC=C(S3)Br
CHEMBL1356206 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
439 7 1 6 5.6 CCOC1=CC=C(C=C1)CNC(=O)C2=C(C3=C(N=CN=C3S2)N(C)C4CCCCC4)C
CHEMBL1607085 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
356 5 1 5 3.5 CC1=CC2=CC=CC=C2N3C1=NN=C3SCC(=O)NCC4CCCO4
CHEMBL1301318 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
444 8 2 9 1.8 COC1=CC(=C(C=C1C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CC=N3)OC)OC
CHEMBL1440872 rxfp1_human Human No 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
349 4 3 6 1.0 CNC(=O)NC(=O)CSC1=NC(=O)C(=C(N1)C2=CC=CS2)C#N
CHEMBL1593224 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
394 2 0 5 4.3 C1CN(CCN1C2=CC=CC=C2F)C(=O)C3=CC4=C(S3)C5=CC=CC=C5OC4
CHEMBL1375857 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
327 4 1 5 1.4 C1CC(OC1)CNC(=O)CN2C=NC3=C(C2=O)OC4=CC=CC=C43
CHEMBL1378340 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
421 4 1 5 4.4 COC1=CC=C(C=C1)C(=C2C(N(C(=O)C2=O)C3=CC=CC=N3)C4=CC(=CC=C4)Cl)O
CHEMBL1500596 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
474 7 1 6 3.6 CCN1C2=CC=CC=C2C3(C1=O)C(=C(C(=O)N3CCCN(C)C)O)C(=O)C4=CC5=CC=CC=C5O4
CHEMBL1591154 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
483 6 1 5 5.3 COC1=CC(=C(C=C1)CNC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=C(S4)Br)OC
CHEMBL1302034 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
346 8 1 5 3.8 CCC1=C(N=C2C(=CC=CC2=C1)C)SCC(=O)NCC(=O)OCC
CHEMBL1513016 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
444 5 1 3 4.6 CCOC1=CC=CC=C1NC(=O)C2=CN(C(=O)C3=C2C4=CC=CC=C4N3C)C5CCCCC5
CHEMBL1397347 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
391 6 1 3 3.3 CC1=CC(=CC=C1)CNC(=O)CCCN2C3=C(C=CC(=C3)F)N4C=CC=C4C2=O
CHEMBL1534658 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
441 6 1 6 5.8 CC1=C(SC2=NC=NC(=C12)N(C)C3CCCCC3)C(=O)NCC4=CC=C(C=C4)SC
CHEMBL1413946 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
255 3 0 5 2.6 C1=CC=C2C(=C1)C3=C(O2)C(=NC=N3)SCCC#N
CHEMBL11909 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
267 2 4 8 -1.1 C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O
CHEMBL1318769 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
479 8 2 5 5.3 COC1=C(C=C(C=C1)C2=NC3=NNC(=C3C(=C2)C(=O)NCCC4=CC=CC=C4)C5=CC=CC=C5)OC
CHEMBL1315511 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
462 8 2 6 5.7 CCOC1=C(C=C(C=C1)C(=O)NC2=C(OC3=CC=CC=C32)C(=O)NC4=CC=CC=C4F)OCC
CHEMBL1348101 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
309 4 1 4 3.9 CC1=CC=C(C=C1)C(=O)NC2=NN=C(S2)CC3=CC=CC=C3
CHEMBL1358814 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
332 4 1 5 5.2 CC1=CC(=CC=C1)NC2=NC(=NC(=C2C#N)C3=CC=CC=C3)SC
CHEMBL1368416 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
414 6 1 8 1.0 C1=CC2=NC(=CC(=O)N2C=C1)CSC3=NC4=C(C(=O)N3CCC(=O)O)SC=C4
CHEMBL1340736 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
359 4 2 6 3.3 C1=CC=C2C(=C1)C=CC(=C2S(=O)(=O)N)SC3=CC=CC=C3C(=O)O
CHEMBL1322400 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
407 4 2 6 5.3 CC1=C(C=C(C=C1)NC(=O)C2=C(C3=C(S2)N=C(C=C3)C4=CC(=CC=C4)OC)N)F
CHEMBL1335235 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
403 5 1 7 2.2 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NC4=CC(=C(C=C4)F)F
CHEMBL1318189 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
493 3 0 8 3.0 CN1CCN(CC1)C2=NC3=C(N=NN3C4=C2SC=C4)S(=O)(=O)C5=CC=C(C=C5)Br
CHEMBL1315996 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
381 5 1 5 4.6 COC1=CC=CC(=C1)CNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC=CC=C5
CHEMBL1318506 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
325 2 1 6 1.8 CC1=CC(=NC2=NC(=NN12)C(=O)NC3=CC4=C(C=C3)OCCO4)C
CHEMBL1318320 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
346 3 0 5 3.3 C1=CC=C(C=C1)N2C=CN(C(=O)C2=O)CC3=CC(=CC=C3)C(F)(F)F
CHEMBL1396136 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
344 3 0 4 5.1 CC1=CC2=C(O1)C=C3N2C(=NN=C3SCC4=CC=C(C=C4)Cl)C
CHEMBL1390399 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
296 3 1 4 4.5 CC1=C(SC2=CC=CC=C12)C(=O)C3=CC=CC=C3C(=O)O
CHEMBL1408014 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
367 5 1 5 1.2 C1COCCN1CCNC(=O)CN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O
CHEMBL1356105 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
456 8 1 6 4.6 C1=CC=C(C=C1)N2C(=NN=N2)SCCNCC3=CC=C(O3)C4=CC=C(C=C4)Br
CHEMBL1384046 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
427 6 0 8 0.7 CCOC(=O)N1CCN(CC1)C(=O)CSC2=NN3C(=NN=C3C4=CN=CC=C4)C=C2
CHEMBL1355268 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
409 5 1 5 5.7 CC1=CC(=CC=C1)CNC(=O)C2=C(C3=C(N=CN=C3S2)N(C)C4CCCCC4)C
CHEMBL1398397 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
312 1 1 3 3.8 CC1=CC=C(C=C1)N2C(=O)C3=C(NC2=O)SC4=C3CCCC4
CHEMBL1413736 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
423 7 1 8 3.7 CC1=NN=C(S1)N2C(C(=C(C2=O)O)C(=O)C3=CC=CO3)C4=CC=C(C=C4)OCC=C
CHEMBL1357046 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
401 4 1 5 4.9 CC1=CC2=C(O1)C=C3N2C(=NN=C3SCC(=O)NC4=C(C(=CC=C4)Cl)C)C
CHEMBL1397047 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
516 12 1 6 6.4 CCOC1=C(C=C(C=C1)CCNC(=O)CSC2=NC3=CC=CC=C3N=C2CC4=CC=C(C=C4)C)OCC
CHEMBL1397611 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
432 6 2 4 6.3 CC1=CC=C(C=C1)OCC(=O)NC2=CC3=C(C=C2)N=C(C=C3C)NC4=CC(=CC=C4)Cl
CHEMBL1467713 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
401 6 2 7 2.5 CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3OC
CHEMBL1418824 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
400 4 0 8 0.3 CCOC(=O)N1CCN(CC1)S(=O)(=O)C2=C(N=C3N(C2=O)C(=CS3)C)C
CHEMBL1417116 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
249 2 1 4 1.5 CSC1=NC(=O)C(=C(N1)C2=CC=CS2)C#N
CHEMBL1423531 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
424 6 1 5 4.6 C1=CC=C(C=C1)CCN2C(C(=C(C2=O)O)C(=O)C3=CC4=CC=CC=C4O3)C5=CC=NC=C5
CHEMBL1429474 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
349 5 1 6 2.8 C1CC(OC1)CNC(=O)CSC2=NC=NC3=C2C4=C(S3)CCC4
CHEMBL1466048 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
467 8 1 8 2.1 COC1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)CN3C(=O)C4=C(C3=O)N=CC=C4)OC
CHEMBL1463377 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
425 4 1 3 4.6 CC1=C2C(=CC(=C1)Br)C(=CC(=N2)C3=CC=CC=C3)C(=O)NCC4CCCO4
CHEMBL1464025 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
335 5 0 5 4.1 CCOC(=O)C(=CC1=CC2=CC=CC=C2N=C1N3CCCCC3)C#N
CHEMBL1476377 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
472 6 1 5 4.5 COC1=CC=C(C=C1)NC(=O)CN2C3=C(C(=O)N(C2=O)CC4=CC=CC=C4)SC5=CC=CC=C53
CHEMBL1459809 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
290 3 1 4 2.6 C=CCN1C(=O)C2=C(NC1=S)SC=C2C3=CC=CO3
CHEMBL1416012 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
441 4 0 3 5.3 CC(C)C1=CC=C(C=C1)N2C(=O)N(C3=CC=CC=C3S2(=O)=O)CC4=CC=CC=C4Cl
CHEMBL1456558 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
398 7 1 7 1.7 CN(C)S(=O)(=O)C1=CC=C(C=C1)C(=O)OCC(=O)NC2=C(N=CC=C2)Cl
CHEMBL1422131 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
547 11 2 8 2.0 CCOC(=O)CCCCC(=O)C1=C(NC(=O)N1)CSC2=NC3=C(C4=C(N3C)C=CC(=C4)Br)N=N2
CHEMBL1435046 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
380 8 1 4 5.0 CC(C)CCNC(=O)CSC1=NC2=CC=CC=C2N=C1CC3=CC=CC=C3
CHEMBL1494680 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
369 4 1 5 4.7 C1=CC=C(C=C1)CNC2=NC3=C(N=NN3C4=CC=CC=C42)C5=CC=C(C=C5)F
CHEMBL1525799 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
428 5 1 5 4.8 CCOC1=CC(=C(C=C1)C(=C2C(N(C(=O)C2=O)C3=CC=CC=N3)C4=CC=C(C=C4)C)O)C
CHEMBL1469191 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
510 10 2 8 1.5 COC1=C(C=C(C=C1)N2C(=O)C3=CC=CC=C3C(=N2)C(=O)NCC(=O)NCCCN4CCOCC4)OC
CHEMBL1491753 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
360 6 2 3 4.0 CC(C(=O)NC1=CC=C(C=C1)NC(=O)C2=CC=CC=C2)OC3=CC=CC=C3
CHEMBL1496411 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
277 2 3 7 1.0 C1=CC(=CC=C1NN=C2C(=O)NC(=O)NC2=O)[N+](=O)[O-]
CHEMBL1523965 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
487 5 1 11 5.5 C1=CC(=CC(=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=CS3)C(F)(F)F)C#N)C(F)(F)F
CHEMBL1525378 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
371 6 1 6 1.0 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NCC4=CC=CO4
CHEMBL1529358 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
405 5 2 3 6.2 CC(C)C1=CC=C(C=C1)OCC(=O)NC(=S)NC2=C3C=CC=C4C3=C(CC4)C=C2
CHEMBL1513368 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
503 8 1 10 5.2 CCOC(=O)C1=CC=C(C=C1)NC(=O)CSC2=C(C(=CC(=N2)C3=CC=C(C=C3)F)C(F)(F)F)C#N
CHEMBL1505221 rxfp1_human Human No 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
452 4 1 8 3.9 CC1=NN(C2=C1C(=CC(=N2)C3=CC=C(C=C3)Br)C(F)(F)F)CCC4=NNN=N4
CHEMBL1526978 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
212 0 1 3 2.7 C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
CHEMBL1508887 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
396 2 1 4 3.9 C1=CC2=CC3=C(C=C2C(=C1)Br)C(=O)N(C3=O)C4=CC=CC(=C4)C(=O)O
CHEMBL1490578 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
315 5 1 7 1.7 CCC(C(=O)O)SC1=NN2C(=NN=C2C3=CN=CC=C3)C=C1
CHEMBL1531718 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
392 6 1 8 2.0 CC1=CC=CC(=C1)C(=O)NC2=NN=C(S2)S(=O)(=O)N(C)CC3=CC=CO3
CHEMBL1528897 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
333 3 2 6 0.9 CC1=C(C=CC=C1[N+](=O)[O-])C(=O)NNC2=CC(=O)N(C(=O)N2C)C
CHEMBL1592153 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
368 5 1 5 4.5 CCC1=CC(=CC=C1)NC(=O)CSC2=NN=CN3C2=CC4=C3C=CS4
CHEMBL1581437 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
430 5 1 7 4.4 CC1=CC(=NO1)N2C(C(=C(C2=O)O)C(=O)C3=CC4=CC=CC=C4O3)C5=CC=CC=C5OC
CHEMBL1583111 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
330 5 0 5 1.1 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCOC3=CC=C(C=C3)OC
CHEMBL1555399 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
423 6 1 5 6.1 CCC1=CC=C(C=C1)CNC(=O)C2=C(C3=C(N=CN=C3S2)N(C)C4CCCCC4)C
CHEMBL1530681 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
419 3 0 5 3.9 CC(=O)C1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(S3)C5=CC=CC=C5OC4
CHEMBL1533261 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
465 5 0 8 2.1 COC1=C(C=C(C=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)S(=O)(=O)N4CCOC5=CC=CC=C54
CHEMBL1565140 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
402 6 1 5 4.9 CC1=C(C=C(C=C1)OCC(=O)NC2=CC3=NN(N=C3C=C2)C4=CC=C(C=C4)OC)C
CHEMBL1525704 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
305 3 0 7 1.9 C1C2=CC(=CC(=C2OCO1)CSC3=NC=CC=N3)[N+](=O)[O-]
CHEMBL1562552 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
389 6 1 7 1.4 CC(C)NS(=O)(=O)C1=C(C=CC(=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)OC
CHEMBL1556192 rxfp1_human Human No 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
377 5 1 7 1.5 CC(C)NS(=O)(=O)C1=C(C=CC(=C1)F)CN2C(=O)C3=C(C2=O)N=CC=C3
CHEMBL1571921 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
460 9 1 4 5.7 CCCN(CCC)CCNC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC=C(S3)Br
CHEMBL1610070 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
423 6 1 7 3.1 CN(CC1=CC=CC=C1)S(=O)(=O)C2=NN=C(S2)NC(=O)C3=CC(=CC=C3)Cl
CHEMBL1598484 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
429 7 1 5 4.8 CCC1=CC=CC=C1NC(=O)COC2=CC3=C(C=C2)OC(=CC3=O)C4=CC=C(C=C4)OC
CHEMBL1604187 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
291 4 1 5 1.3 CC(=O)CSC1=NC(=O)C(=C(N1)C2=CC=CS2)C#N
CHEMBL1591352 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
454 6 1 5 5.3 CC1=CC=C(C=C1)C(=O)C2=CN(C3=C(C2=O)C=CC(=N3)C)CC(=O)NC4=CC=C(C=C4)C(C)C
CHEMBL1604935 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
329 6 0 7 2.0 CCC(C(=O)OC)SC1=NN2C(=NN=C2C3=CN=CC=C3)C=C1
CHEMBL1602197 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
383 4 1 5 4.8 CC1=CC(=C(C=C1)NC(=O)CSC2=NN=C(N3C2=CC4=C3C=CS4)C)C
CHEMBL1980641 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
424 5 2 8 0.8 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)NNC=C3C=NN=C3C4=CC=C(C=C4)F
CHEMBL1999641 rxfp1_human Human Yes 4.9 Potency = 14125.4 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
377 4 1 5 3.4 CC1=C(N2C=CC=CC2=N1)C(=O)NN=C(C)C3=CC=C(C=C3)N4CCOCC4
CHEMBL1349353 rxfp1_human Human Yes 5.8 Potency = 1584.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
471 2 0 6 4.5 CC(C)C(=O)N1CCC2(CC1)C3(CC(=NO3)C4=CC=C(C=C4)Cl)C(=O)C5=C(O2)C=CC(=C5)F
CHEMBL1349353 rxfp1_human Human Yes 5.8 Potency = 1584.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
471 2 0 6 4.5 CC(C)C(=O)N1CCC2(CC1)C3(CC(=NO3)C4=CC=C(C=C4)Cl)C(=O)C5=C(O2)C=CC(=C5)F
CHEMBL1522190 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
513 11 1 8 4.1 CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CC(=C(C=C3)OCCC(C)C)OC)CCN4CCOCC4)O
CHEMBL1580962 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
331 1 2 4 4.2 CC(C)C1=C2CCCCC2=C3C4=C(C(=O)NC(=S)N4)SC3=N1
CHEMBL1402642 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
379 4 1 7 3.1 CC1=CC=C(O1)C(=O)C2=C(C(=O)N(C2C3=CC=C(C=C3)F)C4=NC=CC=N4)O
CHEMBL1577034 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
445 7 2 6 1.3 CCC(=O)NC1=CC=C(C=C1)NC(=O)CSC2=NC3=C(N2CC)C(=O)N(C(=O)N3C)C
CHEMBL1511291 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
460 6 2 3 2.7 CCN(CC1=NC(=O)C2=CC(=CC(=C2N1)Br)Br)CC(=O)NC(C)C
CHEMBL1551209 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
430 8 1 5 4.8 COC1=CC=C(C=C1)CNC(=O)CSC2=NC3=CC=CC=C3N=C2CC4=CC=CC=C4
CHEMBL1354972 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
389 7 1 7 1.5 CCCNS(=O)(=O)C1=C(C=CC(=C1)CN2C(=O)C3=C(C2=O)N=CC=C3)OC
CHEMBL1331202 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
348 2 1 4 4.2 CC1=CC=C(S1)C2=NC3=C(C=C(C=C3)Br)C(=C2)C(=O)O
CHEMBL1405932 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
555 6 1 8 3.0 C1=CC(=CC=C1CN2C(=O)C3=C(C=CS3)N=C2SCC4=CC(=O)N5C=C(C=CC5=N4)Br)C(=O)O
CHEMBL1347701 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
430 5 1 7 4.4 CC1=CC(=NO1)N2C(C(=C(C2=O)O)C(=O)C3=CC4=CC=CC=C4O3)C5=CC(=CC=C5)OC
CHEMBL1362095 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
430 6 2 6 0.8 CCN1C2=C(N=C1SCC(=O)NC3=CC=C(C=C3)NC(=O)C)N(C(=O)N(C2=O)C)C
CHEMBL1500823 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
402 7 1 8 2.0 C1CC(OC1)CNC(=O)CSC2=NC=NC3=C2N=NN3CC4=CC=CC=C4F
CHEMBL1437080 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
375 6 1 7 1.4 CC1=CSC2=NC(=CC(=O)N12)COC(=O)CNC(=O)C3=CC=C(C=C3)F
CHEMBL1360279 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
393 5 2 7 2.3 CN1C2=CC=CC=C2C3=C1N=C(N=N3)SCC(=O)NC4=CC=CC(=C4)C(=O)O
CHEMBL1419486 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
411 7 1 6 1.9 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NCC4=CC(=CC=C4)OC
CHEMBL1519470 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
391 4 1 6 4.2 CC1=CC2=C(O1)C=C3N2C=NN=C3SCC(=O)NC4=C(C=C(C=C4)Cl)F
CHEMBL1595485 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
394 6 1 5 5.1 CCC1=CC=CC(=C1NC(=O)CSC2=NN=C(N3C2=CC4=C3C=CO4)CC)C
CHEMBL1505540 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
521 5 1 8 3.3 CC1=C(C=C(C=C1)F)NC(=O)C2=C(C3=C(S2)N=CN(C3=O)CC(=O)N4CCN(CC4)C5=CC=CC=N5)C
CHEMBL1344555 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
271 3 0 5 2.9 CN(C)C1=CC=C(C=C1)C2=NN=C(O2)C3=CC=CS3
CHEMBL1499143 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
356 3 1 7 2.4 C1=CC(=CN=C1)C(=O)NCC2=NN=C3N2C=C(C=C3C(F)(F)F)Cl
CHEMBL1597835 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
352 4 1 5 3.8 CC1=CC(=CC(=C1)NC(=O)CSC2=NN=CN3C2=CC4=C3C=CO4)C
CHEMBL1449543 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
380 4 1 5 4.6 CC1=CC(=C(C(=C1)C)NC(=O)CSC2=NN=CN3C2=CC4=C3C=C(O4)C)C
CHEMBL1441169 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
516 7 1 7 3.3 CCN1C2=CC=CC=C2C3(C1=O)C(=C(C(=O)N3CCCN4CCOCC4)O)C(=O)C5=CC6=CC=CC=C6O5
CHEMBL1456629 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
339 6 1 4 1.2 CC1=CC=C(C=C1)CNC(=O)CCCN2C(=O)C3=NC=CN3C(=N2)C
CHEMBL1457998 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
477 6 1 7 3.9 C1CCN(CC1)S(=O)(=O)C2=CC(=C(C=C2)Cl)NC(=O)CSC3=NC=NC4=CC=CC=C43
CHEMBL1480089 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
309 5 2 6 2.2 COC(=O)C1=C(C=CS1)NC(=O)C2CC=CCC2C(=O)O
CHEMBL1594498 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
411 4 1 5 4.9 CC1=NC(=CC=C1)N2C(C(=C(C2=O)O)C(=O)C3=CC=CS3)C4=CC=C(C=C4)Cl
CHEMBL1441242 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
403 7 1 5 4.8 CC1=C(C(C(=C(N1)SCC(=O)C2=CC=C(C=C2)Cl)C#N)CC(C)C)C(=O)C
CHEMBL1537461 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
352 4 3 4 4.5 C1=CC=C(C=C1)OCC(=O)NC(=S)NC2=CC=CC3=C2C=CC(=C3)O
CHEMBL1319322 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
403 5 1 7 2.2 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCCC(=O)NC4=C(C=C(C=C4)F)F
CHEMBL1546017 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
356 5 1 5 3.5 CC1=CC2=NN=C(N2C3=CC=CC=C13)SCC(=O)NCC4CCCO4
CHEMBL1494501 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
397 6 1 6 1.5 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCC(=O)NCC4=CC(=CC=C4)OC
CHEMBL1523214 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
288 2 1 5 2.5 CC1=NN(C(=O)C2=C1SC3=CC=CC=C32)C(C)C(=O)O
CHEMBL1538711 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
314 3 3 5 2.3 C1=CC=C(C(=C1)C(=O)NNC2=NC(=O)C3=C(S2)N=CC=C3)O
CHEMBL1421499 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
480 9 2 7 1.5 COC1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3C(=N2)C(=O)NCC(=O)NCCCN4CCOCC4
CHEMBL1600661 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
244 1 1 2 2.0 C1CC2=C(C1)N(C(=O)NC2=S)C3=CC=CC=C3
CHEMBL1462354 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
410 6 1 7 0.1 CC1=CC=CN2C1=NC(=C(C2=O)C=C(C#N)C(=O)NCCOC)N3CCN(CC3)C
CHEMBL1329775 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
385 5 1 6 1.7 CN1C(=O)C2=C(C=CS2)N3C1=NN=C3CCC(=O)NCC4=CC=C(C=C4)F
CHEMBL1421579 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
472 11 1 8 0.4 CCOC(=O)C1CCN(CC1)C(=O)CCC2=NN=C3N2N=C(C=C3)NCCCN4CCCC4=O
CHEMBL1602305 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
399 5 1 6 2.5 CC1=C(C=C(C=C1)NC(=O)CCCC2=NN=C3N2C4=C(C(=O)N3C)SC=C4)F
CHEMBL1552691 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
382 3 1 4 1.8 CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)NC3=C(C(=CC=C3)Cl)Cl
CHEMBL1173709 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
430 3 0 8 2.8 CC1=CC(=C(C=C1)C)S(=O)(=O)C2=C3N=C(C4=C(N3N=N2)C=CS4)N5CCOCC5
CHEMBL1360045 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
234 3 1 5 2.1 CC(C(=O)O)SC1=NC2=CC=CC=C2N=C1
CHEMBL1162415 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
345 5 2 5 4.2 CC(=O)C1=C(C=C(S1)C(C)(C)C)NC(=O)C2=CC=CC=C2C(=O)O
CHEMBL1449527 rxfp1_human Human No 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
504 10 0 7 5.9 CCCCC1=CC2=C(C(=O)C(C(=O)C2=CN1CC(C)C)(C)OC(=O)C3=CC=C(C=C3)OC)C4=CC=CO4
CHEMBL1450861 rxfp1_human Human Yes 4.8 Potency = 15848.9 Funct
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
458 7 1 7 5.3 CCCOC1=CC=C(C=C1)C2C(=C(C(=O)N2C3=NOC(=C3)C)O)C(=O)C4=CC5=CC=CC=C5O4
CHEMBL1332222 rxfp1_human Human Yes