Variation Browser

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Receptor Position GPCRdb Segment Variant Mutation type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
Receptor Position GPCRdb Segment Variant Mutation Type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
5ht6r_human 26 1.32x32 TM1 S => GlnfsTer47 frameshift 4.232e-05 2 47254 0 None None
5ht6r_human 91 23.49x49 ECL1 R => AlafsTer17 frameshift 8.337e-06 1 119954 0 None None
5ht6r_human 151 4.50x50 TM4 W => Ter stop gained 8.418e-06 1 118794 0 None None
5ht6r_human 310 7.43x42 TM7 Y => Ter stop gained 8.256e-06 1 121118 0 None None
5ht6r_human 361 C-term R => ProfsTer5 frameshift 9.53e-06 1 104930 0 None None
5ht6r_human 367 C-term Q => Ter stop gained 1.187e-05 1 84230 0 None None
5ht6r_human 410 C-term L => AlafsTer67 frameshift 7.8e-05 4 51282 0 None None
5ht6r_human 429 C-term E => Ter stop gained 2.136e-05 2 93642 0 None None
5ht6r_human 3 N-term P => S missense 1.044e-05 1 95806 0 nan 0.478
5ht6r_human 6 N-term G => R missense 1.186e-05 1 84314 0 nan 0.422
5ht6r_human 8 N-term T => I missense 8.43e-05 8 94898 0 nan 0.0
5ht6r_human 9 N-term A => S missense 2.112e-05 2 94708 0 nan 0.0
5ht6r_human 15 N-term W => C missense 2.366e-05 2 84544 0 0.02 0.319
5ht6r_human 16 N-term G => R missense 1.192e-05 1 83884 0 nan 0.34
5ht6r_human 16 N-term G => E missense 1.229e-05 1 81338 0 nan 0.007
5ht6r_human 16 N-term G => V missense 1.229e-05 1 81338 0 nan 0.255
5ht6r_human 17 N-term A => T missense 1.247e-05 1 80202 0 0.48 0.01
5ht6r_human 18 N-term G => R missense 0.00141 109 77300 0 0.16 0.011
5ht6r_human 19 N-term P => L missense 4.305e-05 3 69680 0 0.16 0.001
5ht6r_human 24 N-term G => V missense 9.722e-05 5 51428 0 0.3 0.17
5ht6r_human 27 1.33x33 TM1 G => C missense 2.521e-05 1 39668 0 0.04 0.884
5ht6r_human 29 1.35x35 TM1 V => G missense 5.179e-05 2 38620 0 0.02 0.991
5ht6r_human 29 1.35x35 TM1 V => A missense 2.589e-05 1 38620 0 0.0 0.97
5ht6r_human 30 1.36x36 TM1 A => E missense 2.565e-05 1 38986 0 0.0 0.997
5ht6r_human 34 1.40x40 TM1 C => S missense 2.281e-05 1 43842 0 0.47 0.074
5ht6r_human 34 1.40x40 TM1 C => Y missense 2.267e-05 1 44106 0 0.0 0.791
5ht6r_human 36 1.42x42 TM1 V => A missense 6.484e-05 3 46266 0 0.0 0.55
5ht6r_human 43 1.49x49 TM1 A => V missense 8.762e-05 6 68480 0 0.0 0.909
5ht6r_human 45 1.51x51 TM1 S => A missense 1.355e-05 1 73798 0 0.57 0.005
5ht6r_human 45 1.51x51 TM1 S => P missense 1.355e-05 1 73798 0 0.22 0.319
5ht6r_human 45 1.51x51 TM1 S => T missense 1.355e-05 1 73798 0 0.78 0.005
5ht6r_human 45 1.51x51 TM1 S => W missense 0.001153 86 74620 0 0.18 0.856
5ht6r_human 46 1.52x52 TM1 L => P missense 1.268e-05 1 78872 0 0.0 1.0
5ht6r_human 47 1.53x53 TM1 L => P missense 0.0001207 10 82852 0 0.0 0.997
5ht6r_human 48 1.54x54 TM1 I => M missense 2.307e-05 2 86706 0 0.02 0.991
5ht6r_human 49 1.55x55 TM1 A => V missense 1.124e-05 1 88962 0 1.0 0.013
5ht6r_human 53 1.59x59 TM1 T => A missense 9.987e-06 1 100126 0 0.28 0.012
5ht6r_human 55 12.48x48 ICL1 P => T missense 1.93e-05 2 103650 0 0.02 0.155
5ht6r_human 62 2.40x40 TM2 N => S missense 1.742e-05 2 114784 0 0.0 0.954
5ht6r_human 64 2.42x42 TM2 F => L missense 8.637e-06 1 115778 0 0.0 1.0
5ht6r_human 67 2.45x45 TM2 S => P missense 8.533e-06 1 117190 0 0.0 1.0
5ht6r_human 69 2.47x47 TM2 F => L missense 8.467e-06 1 118106 0 0.13 0.306
5ht6r_human 79 2.57x56 TM2 V => M missense 8.381e-06 1 119312 0 0.0 0.999
5ht6r_human 87 2.65x64 TM2 A => V missense 9.18e-05 11 119826 0 0.35 0.002
5ht6r_human 87 2.65x64 TM2 A => G missense 8.345e-06 1 119826 0 0.24 0.362
5ht6r_human 89 2.67x66 TM2 Y => H missense 5.838e-05 7 119908 0 0.25 0.994
5ht6r_human 89 2.67x66 TM2 Y => C missense 0.0002335 28 119920 0 0.2 0.518
5ht6r_human 90 2.68x67 TM2 G => R missense 8.332e-06 1 120016 0 0.04 0.979
5ht6r_human 91 23.49x49 ECL1 R => C missense 8.333e-06 1 120008 0 0.17 0.935
5ht6r_human 96 3.22x22 TM3 R => C missense 8.342e-06 1 119874 0 0.08 0.846
5ht6r_human 103 3.29x29 TM3 T => P missense 8.328e-06 1 120082 0 0.06 0.167
5ht6r_human 109 3.35x35 TM3 C => W missense 8.31e-06 1 120344 0 0.0 0.995
5ht6r_human 110 3.36x36 TM3 C => W missense 1.662e-05 2 120348 0 0.0 0.999
5ht6r_human 112 3.38x38 TM3 A => T missense 1.661e-05 2 120380 0 0.0 1.0
5ht6r_human 115 3.41x41 TM3 L => F missense 1.661e-05 2 120436 0 0.0 0.999
5ht6r_human 118 3.44x44 TM3 C => Y missense 4.981e-05 6 120446 0 0.0 1.0
5ht6r_human 120 3.46x46 TM3 I => L missense 8.302e-06 1 120458 0 0.0 0.999
5ht6r_human 121 3.47x47 TM3 S => N missense 8.302e-06 1 120448 0 0.0 1.0
5ht6r_human 126 3.52x52 TM3 L => Q missense 1.661e-05 2 120406 0 0.0 0.997
5ht6r_human 136 34.55x55 ICL2 L => R missense 8.328e-06 1 120084 0 1.0 0.349 GP (contact)
5ht6r_human 138 34.57x57 ICL2 M => L missense 2.5e-05 3 120018 0 0.0 0.926 GP (contact)
5ht6r_human 138 34.57x57 ICL2 M => K missense 8.335e-06 1 119980 0 0.02 0.401 GP (contact)
5ht6r_human 143 4.42x42 TM4 A => S missense 7.519e-05 9 119700 0 0.0 0.999
5ht6r_human 145 4.44x44 TM4 A => S missense 8.36e-06 1 119616 0 0.07 0.297
5ht6r_human 154 4.53x53 TM4 A => T missense 8.442e-06 1 118462 0 0.0 0.995
5ht6r_human 168 ECL2 E => K missense 4.252e-05 5 117602 0 0.55 0.013
5ht6r_human 172 ECL2 A => T missense 8.506e-06 1 117558 0 0.45 0.003
5ht6r_human 173 ECL2 R => W missense 4.253e-05 5 117556 0 0.02 0.773
5ht6r_human 173 ECL2 R => Q missense 8.503e-06 1 117608 0 0.78 0.009
5ht6r_human 173 ECL2 R => P missense 8.503e-06 1 117608 0 0.28 0.007
5ht6r_human 174 ECL2 P => S missense 8.502e-06 1 117618 0 0.83 0.006
5ht6r_human 181 45.51x51 ECL2 R => G missense 8.454e-06 1 118286 0 0.12 0.609
5ht6r_human 183 ECL2 L => R missense 8.434e-06 1 118570 0 0.67 0.058
5ht6r_human 190 5.40x41 TM5 L => F missense 8.376e-06 1 119386 0 0.0 1.0
5ht6r_human 193 5.43x44 TM5 S => L missense 8.363e-06 1 119576 0 0.0 0.995
5ht6r_human 202 5.52x52 TM5 G => D missense 8.351e-06 1 119748 0 0.01 0.817
5ht6r_human 202 5.52x52 TM5 G => V missense 3.34e-05 4 119748 0 0.19 0.058
5ht6r_human 204 5.54x54 TM5 I => V missense 8.355e-06 1 119684 0 0.02 0.972
5ht6r_human 209 5.59x59 TM5 C => Y missense 1.679e-05 2 119134 0 0.0 0.721
5ht6r_human 216 5.66x66 TM5 R => S missense 8.503e-06 1 117604 0 0.02 0.993 GP (contact)
5ht6r_human 216 5.66x66 TM5 R => C missense 8.503e-06 1 117604 0 0.0 0.997 GP (contact)
5ht6r_human 220 5.70x70 TM5 V => M missense 4.342e-05 5 115142 0 0.13 0.164
5ht6r_human 221 5.71x71 TM5 Q => K missense 0.0002103 24 114098 1 0.09 0.593 GP (contact)
5ht6r_human 226 5.76x76 TM5 T => P missense 9.391e-06 1 106482 0 0.23 0.001
5ht6r_human 227 ICL3 T => A missense 2.878e-05 3 104238 0 0.59 0.004
5ht6r_human 227 ICL3 T => N missense 9.669e-06 1 103422 0 0.21 0.219
5ht6r_human 228 ICL3 G => S missense 9.826e-06 1 101766 0 0.29 0.108
5ht6r_human 230 ICL3 A => V missense 1.034e-05 1 96690 0 0.13 0.297
5ht6r_human 231 ICL3 S => T missense 1.068e-05 1 93618 0 0.7 0.004
5ht6r_human 243 ICL3 P => L missense 8.26e-06 1 121072 0 0.12 0.426
5ht6r_human 244 ICL3 R => C missense 0.0001074 13 121076 0 0.24 0.009
5ht6r_human 244 ICL3 R => H missense 8.259e-06 1 121074 0 0.64 0.009
5ht6r_human 245 ICL3 P => S missense 2.477e-05 3 121090 0 0.47 0.014
5ht6r_human 245 ICL3 P => T missense 8.258e-06 1 121090 0 0.32 0.008
5ht6r_human 245 ICL3 P => R missense 2.477e-05 3 121110 0 0.27 0.281
5ht6r_human 248 ICL3 E => K missense 8.252e-06 1 121190 0 0.55 0.032
5ht6r_human 254 ICL3 R => H missense 5.778e-05 7 121146 0 0.01 0.954
5ht6r_human 255 ICL3 L => P missense 8.254e-06 1 121156 0 0.02 0.974
5ht6r_human 257 6.24x24 TM6 T => M missense 1.651e-05 2 121148 0 0.23 0.029
5ht6r_human 259 6.26x26 TM6 H => N missense 1.651e-05 2 121146 0 0.04 0.348 GP (contact)
5ht6r_human 261 6.28x28 TM6 R => S missense 8.26e-06 1 121072 0 0.2 0.069 GP (contact)
5ht6r_human 269 6.36x36 TM6 T => M missense 5.788e-05 7 120934 0 0.0 0.999 GP (contact)
5ht6r_human 284 6.51x51 TM6 F => S missense 1.666e-05 2 120060 0 0.0 0.995
5ht6r_human 284 6.51x51 TM6 F => Y missense 1.666e-05 2 120060 0 0.05 0.934
5ht6r_human 288 6.55x55 TM6 N => Y missense 8.382e-06 1 119304 0 0.0 0.979
5ht6r_human 290 6.57x57 TM6 V => L missense 8.415e-06 1 118832 0 0.28 0.016
5ht6r_human 292 6.59x59 TM6 A => T missense 1.765e-05 2 113326 0 0.02 0.954
5ht6r_human 293 6.60x60 TM6 V => M missense 7.015e-05 8 114046 0 0.04 0.997
5ht6r_human 295 ECL3 D => N missense 8.668e-06 1 115370 0 0.04 0.009
5ht6r_human 295 ECL3 D => H missense 8.668e-06 1 115370 0 0.01 0.676
5ht6r_human 296 ECL3 C => R missense 1.722e-05 2 116116 0 0.0 0.874
5ht6r_human 298 7.31x30 TM7 S => F missense 1.702e-05 2 117496 0 0.0 0.797
5ht6r_human 299 7.32x31 TM7 P => S missense 8.48e-06 1 117920 0 0.45 0.155
5ht6r_human 303 7.36x35 TM7 D => N missense 1.665e-05 2 120106 0 0.13 0.85
5ht6r_human 303 7.36x35 TM7 D => E missense 1.662e-05 2 120310 0 0.07 0.758
5ht6r_human 307 7.40x39 TM7 W => R missense 3.309e-05 4 120894 0 0.0 1.0
5ht6r_human 309 7.42x41 TM7 G => C missense 9.089e-05 11 121026 0 0.0 1.0
5ht6r_human 309 7.42x41 TM7 G => V missense 8.262e-06 1 121040 0 0.0 1.0
5ht6r_human 311 7.44x43 TM7 C => R missense 1.651e-05 2 121136 0 0.0 0.993 SodiumPocket MicroSwitch
5ht6r_human 314 7.47x47 TM7 T => A missense 8.25e-06 1 121214 0 0.05 0.627
5ht6r_human 314 7.47x47 TM7 T => I missense 7.425e-05 9 121218 0 0.0 0.972
5ht6r_human 315 7.48x48 TM7 M => R missense 1.65e-05 2 121242 0 0.0 0.866
5ht6r_human 320 7.53x53 TM7 Y => H missense 8.244e-06 1 121296 0 0.0 1.0 SodiumPocket MicroSwitch
5ht6r_human 322 7.55x55 TM7 L => P missense 8.244e-06 1 121294 0 0.0 0.993 GP (contact)
5ht6r_human 324 8.47x47 H8 M => K missense 8.246e-06 1 121268 0 0.04 0.96 GP (contact)
5ht6r_human 325 8.48x48 H8 R => W missense 2.474e-05 3 121244 0 0.0 0.955 GP (contact)
5ht6r_human 325 8.48x48 H8 R => Q missense 8.249e-06 1 121228 0 0.1 0.087 GP (contact)
5ht6r_human 329 8.52x52 H8 R => W missense 8.259e-06 1 121086 0 0.0 0.991
5ht6r_human 329 8.52x52 H8 R => Q missense 8.261e-06 1 121056 0 0.04 0.532
5ht6r_human 330 8.53x53 H8 A => V missense 4.957e-05 6 121048 0 0.12 0.759
5ht6r_human 332 8.55x55 H8 G => A missense 1.654e-05 2 120922 0 0.46 0.002
5ht6r_human 336 8.59x59 H8 P => R missense 8.283e-06 1 120730 0 0.04 0.686
5ht6r_human 337 8.60x60 H8 C => R missense 8.294e-06 1 120570 0 0.0 0.997
5ht6r_human 339 C-term R => S missense 3.321e-05 4 120432 0 0.03 0.023
5ht6r_human 339 C-term R => C missense 8.303e-06 1 120432 0 0.04 0.01
5ht6r_human 341 C-term P => L missense 1.664e-05 2 120166 0 0.06 0.002
5ht6r_human 342 C-term R => W missense 3.331e-05 4 120096 0 0.24 0.0
5ht6r_human 342 C-term R => Q missense 4.999e-05 6 120022 0 0.44 0.001
5ht6r_human 342 C-term R => L missense 3.333e-05 4 120022 0 0.7 0.024
5ht6r_human 344 C-term R => C missense 1.668e-05 2 119906 0 0.06 0.386
5ht6r_human 350 C-term S => L missense 7.622e-05 9 118082 0 0.0 0.274
5ht6r_human 351 C-term P => L missense 8.513e-06 1 117466 0 0.71 0.002
5ht6r_human 354 C-term R => C missense 8.6e-06 1 116282 0 0.01 0.77
5ht6r_human 355 C-term T => I missense 1.762e-05 2 113526 0 0.09 0.303
5ht6r_human 361 C-term R => W missense 0.00102 104 101982 1 0.0 0.999
5ht6r_human 361 C-term R => Q missense 1.98e-05 2 100990 0 0.04 0.983
5ht6r_human 364 C-term L => I missense 1.067e-05 1 93716 0 0.37 0.166
5ht6r_human 365 C-term S => R missense 1.12e-05 1 89314 0 0.0 0.584
5ht6r_human 367 C-term Q => R missense 1.207e-05 1 82868 0 0.3 0.007
5ht6r_human 371 C-term P => L missense 1.481e-05 1 67526 0 0.12 0.085
5ht6r_human 375 C-term P => T missense 0.002774 157 56606 0 0.29 0.054
5ht6r_human 375 C-term P => L missense 1.779e-05 1 56226 0 0.23 0.002
5ht6r_human 376 C-term P => S missense 1.84e-05 1 54340 0 0.27 0.002
5ht6r_human 376 C-term P => L missense 3.73e-05 2 53620 0 0.26 0.001
5ht6r_human 377 C-term D => H missense 1.906e-05 1 52468 0 0.04 0.006
5ht6r_human 380 C-term S => L missense 0.0001323 6 45346 0 0.23 0.002
5ht6r_human 384 C-term A => T missense 2.648e-05 1 37768 0 nan 0.002
5ht6r_human 384 C-term A => S missense 5.295e-05 2 37768 0 nan 0.0
5ht6r_human 384 C-term A => V missense 0.001309 50 38192 0 nan 0.002
5ht6r_human 388 C-term G => S missense 9.735e-05 3 30816 0 0.75 0.005
5ht6r_human 388 C-term G => C missense 3.245e-05 1 30816 0 0.05 0.013
5ht6r_human 390 C-term S => A missense 3.344e-05 1 29906 0 0.18 0.007
5ht6r_human 393 C-term R => L missense 0.0001694 5 29508 0 0.37 0.0
5ht6r_human 395 C-term T => M missense 0.0001692 5 29544 0 0.06 0.012
5ht6r_human 395 C-term T => K missense 3.385e-05 1 29544 0 0.38 0.034
5ht6r_human 400 C-term L => P missense 2.932e-05 1 34106 0 0.05 0.183
5ht6r_human 402 C-term G => D missense 2.751e-05 1 36356 0 0.14 0.101
5ht6r_human 404 C-term A => T missense 2.407e-05 1 41540 0 0.21 0.002
5ht6r_human 407 C-term D => G missense 1.95e-05 1 51282 0 nan 0.002
5ht6r_human 407 C-term D => E missense 1.884e-05 1 53078 0 nan 0.002
5ht6r_human 408 C-term P => S missense 1.832e-05 1 54596 0 nan 0.002
5ht6r_human 411 C-term P => S missense 1.508e-05 1 66328 0 nan 0.019
5ht6r_human 414 C-term A => T missense 1.366e-05 1 73192 0 nan 0.001
5ht6r_human 415 C-term A => T missense 1.31e-05 1 76346 0 nan 0.004
5ht6r_human 417 C-term A => T missense 7.188e-05 6 83474 0 nan 0.0
5ht6r_human 417 C-term A => V missense 1.181e-05 1 84702 0 1.0 0.0
5ht6r_human 418 C-term V => I missense 6.848e-05 6 87616 0 nan 0.012
5ht6r_human 420 C-term F => C missense 1.085e-05 1 92154 0 nan 0.002
5ht6r_human 423 C-term I => V missense 3.201e-05 3 93720 0 nan 0.0
5ht6r_human 424 C-term D => N missense 2.134e-05 2 93714 0 nan 0.004
5ht6r_human 426 C-term A => T missense 1.061e-05 1 94258 0 nan 0.001
5ht6r_human 426 C-term A => V missense 5.302e-05 5 94302 0 1.0 0.001
5ht6r_human 428 C-term P => H missense 1.066e-05 1 93816 0 nan 0.417
5ht6r_human 429 C-term E => K missense 9.611e-05 9 93642 0 nan 0.006
5ht6r_human 431 C-term R => W missense 3.246e-05 3 92426 0 nan 0.632
5ht6r_human 431 C-term R => Q missense 4.316e-05 4 92688 0 nan 0.002
5ht6r_human 431 C-term R => L missense 1.079e-05 1 92688 0 nan 0.14
5ht6r_human 432 C-term P => L missense 2.171e-05 2 92122 0 1.0 0.0
5ht6r_human 433 C-term H => Y missense 7.624e-05 7 91812 0 nan 0.261
5ht6r_human 434 C-term P => L missense 0.0002646 24 90692 0 nan 0.002
5ht6r_human 439 C-term T => M missense 0.0004897 39 79646 0 nan 0.005


Residue

Diagrams

ICL1 P A L R ICL1ECL1 R W V L ECL1ICL2 P L R Y K L R M ICL2ECL2 W H E L G H A R P P V P G Q C R L L A ECL2ICL3 T G M A S Q A S E T L Q V P R T P R P G V E S A D S R R L A ICL3ECL3 D C I ECL3N-term M V P E P G P T A N S T P A W G A G P P S A P G G N-termC-term P R C P R E R Q A S L A S P S L R T S H S G P R P G L S L Q Q V L P L P L P P D S D S D S D A G S G G S S G L R L T A Q L L L P G E A T Q D P P L P T R A A A A V N F F N I D P A E P E L R P H P L G I P T N C-term S G W V A A A L C V V I A L T A A A N S L L I A L I C T Q N T S N F F L V S L F T S D L M V G L V V M P P A M L N A L Y G A R G L C L L W T A F D V M C C S A S I L N L C L I S L D R Y L L I L S T P L R A L A L V L G A W S L A A L A S F L P L L L G S L P F V L V A S G L T F F L P S G A I C F T Y C R I L L A A R K Q A V Q V A S L T T K H S R K A L K A S L T L G I L L G M F F V T W L P F F V A N I V Q A V C S P G L F D V L T W L G Y C N S T M N P I I Y P L F M R D L G R F K R A F L P C
SnakePlot Download: PNG | SVG S N A A A T L A I V V C L A A A V W G S 1 V S L F T S D L M V G V L V M P P A M L N 2 L C L N L I S A S C C M V D F A T W L L 3 A L A L V L G A W S L A A L A S F L P L 4 Y T F C I A G S P L F F T L G S A V L V F 5 G I L L G M F F V T W L P F F V A N I V 6 I P N M T S N C Y G L W T L V D F L G 7
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Versions

Package Name Version
Django 2.2.1
Python 3.6.7
debug_toolbar Debug Toolbar 1.11
polymorphic Polymorphic 2.0.3
rest_framework Django REST framework 3.9.3
rest_framework_swagger Rest_Framework_Swagger 2.2.0

Time

Resource usage

Resource Value
User CPU time 2438.605 msec
System CPU time 35.578 msec
Total CPU time 2474.183 msec
Elapsed time 2722.743 msec
Context switches 43 voluntary, 58 involuntary

Browser timing

Timing attribute Timeline Milliseconds since navigation start (+length)

Settings from protwis.settings

Setting Value
ABSOLUTE_URL_OVERRIDES {}
ADMINS []
ALLOWED_HOSTS ['*']
APPEND_SLASH True
AUTHENTICATION_BACKENDS ['django.contrib.auth.backends.ModelBackend']
AUTH_PASSWORD_VALIDATORS '********************'
AUTH_USER_MODEL 'auth.User'
BASE_DIR '/home/protwis/gpcrdb_test'
BUILD_CACHE_DIR '/home/protwis/gpcrdb_data/cache'
CACHES {'alignments': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test_alignment', 'OPTIONS': {'MAX_ENTRIES': 1000}}, 'default': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test/', 'OPTIONS': {'MAX_ENTRIES': 10000000}}}
CACHE_MIDDLEWARE_ALIAS 'default'
CACHE_MIDDLEWARE_KEY_PREFIX '********************'
CACHE_MIDDLEWARE_SECONDS 600
CSRF_COOKIE_AGE 31449600
CSRF_COOKIE_DOMAIN None
CSRF_COOKIE_HTTPONLY False
CSRF_COOKIE_NAME 'csrftoken'
CSRF_COOKIE_PATH '/'
CSRF_COOKIE_SAMESITE 'Lax'
CSRF_COOKIE_SECURE False
CSRF_FAILURE_VIEW 'django.views.csrf.csrf_failure'
CSRF_HEADER_NAME 'HTTP_X_CSRFTOKEN'
CSRF_TRUSTED_ORIGINS []
CSRF_USE_SESSIONS False
DATABASES {'default': {'ATOMIC_REQUESTS': False, 'AUTOCOMMIT': True, 'CONN_MAX_AGE': 0, 'ENGINE': 'django.db.backends.postgresql_psycopg2', 'HOST': 'localhost', 'NAME': 'protwis_202107', 'OPTIONS': {}, 'PASSWORD': '********************', 'PORT': '', 'TEST': {'CHARSET': None, 'COLLATION': None, 'MIRROR': None, 'NAME': None}, 'TIME_ZONE': None, 'USER': 'protwis'}}
DATABASE_ROUTERS []
DATA_DIR '/home/protwis/gpcrdb_data'
DATA_UPLOAD_MAX_MEMORY_SIZE 2621440
DATA_UPLOAD_MAX_NUMBER_FIELDS 1000
DATETIME_FORMAT 'N j, Y, P'
DATETIME_INPUT_FORMATS ['%Y-%m-%d %H:%M:%S', '%Y-%m-%d %H:%M:%S.%f', '%Y-%m-%d %H:%M', '%Y-%m-%d', '%m/%d/%Y %H:%M:%S', '%m/%d/%Y %H:%M:%S.%f', '%m/%d/%Y %H:%M', '%m/%d/%Y', '%m/%d/%y %H:%M:%S', '%m/%d/%y %H:%M:%S.%f', '%m/%d/%y %H:%M', '%m/%d/%y']
DATE_FORMAT 'N j, Y'
DATE_INPUT_FORMATS ['%Y-%m-%d', '%m/%d/%Y', '%m/%d/%y', '%b %d %Y', '%b %d, %Y', '%d %b %Y', '%d %b, %Y', '%B %d %Y', '%B %d, %Y', '%d %B %Y', '%d %B, %Y']
DEBUG True
DEBUG_PROPAGATE_EXCEPTIONS False
DEBUG_TOOLBAR_PATCH_SETTINGS False
DECIMAL_SEPARATOR '.'
DEFAULT_CHARSET 'utf-8'
DEFAULT_CONTENT_TYPE 'text/html'
DEFAULT_EXCEPTION_REPORTER_FILTER 'django.views.debug.SafeExceptionReporterFilter'
DEFAULT_FILE_STORAGE 'django.core.files.storage.FileSystemStorage'
DEFAULT_FROM_EMAIL 'webmaster@localhost'
DEFAULT_INDEX_TABLESPACE ''
DEFAULT_NUMBERING_SCHEME 'gpcrdb'
DEFAULT_PROTEIN_STATE 'inactive'
DEFAULT_SITE 'gpcr'
DEFAULT_TABLESPACE ''
DISALLOWED_USER_AGENTS []
DOCUMENTATION_URL 'https://docs.gpcrdb.org/'
EMAIL_BACKEND 'django.core.mail.backends.smtp.EmailBackend'
EMAIL_HOST 'localhost'
EMAIL_HOST_PASSWORD '********************'
EMAIL_HOST_USER ''
EMAIL_PORT 25
EMAIL_SSL_CERTFILE None
EMAIL_SSL_KEYFILE '********************'
EMAIL_SUBJECT_PREFIX '[Django] '
EMAIL_TIMEOUT None
EMAIL_USE_LOCALTIME False
EMAIL_USE_SSL False
EMAIL_USE_TLS False
FILE_CHARSET 'utf-8'
FILE_UPLOAD_DIRECTORY_PERMISSIONS None
FILE_UPLOAD_HANDLERS ['django.core.files.uploadhandler.MemoryFileUploadHandler', 'django.core.files.uploadhandler.TemporaryFileUploadHandler']
FILE_UPLOAD_MAX_MEMORY_SIZE 2621440
FILE_UPLOAD_PERMISSIONS None
FILE_UPLOAD_TEMP_DIR None
FIRST_DAY_OF_WEEK 0
FIXTURE_DIRS []
FORCE_SCRIPT_NAME None
FORMAT_MODULE_PATH None
FORM_RENDERER 'django.forms.renderers.DjangoTemplates'
GOOGLE_ANALYTICS_API '********************'
GOOGLE_ANALYTICS_KEY '********************'
IGNORABLE_404_URLS []
INSTALLED_APPS ('django.contrib.admin', 'django.contrib.auth', 'django.contrib.contenttypes', 'django.contrib.sessions', 'django.contrib.messages', 'django.contrib.staticfiles', 'django.contrib.humanize', 'debug_toolbar', 'rest_framework', 'rest_framework_swagger', 'polymorphic', 'common', 'api', 'news', 'pages', 'home', 'protein', 'family', 'residue', 'alignment', 'similaritysearch', 'similaritymatrix', 'structure', 'ligand', 'interaction', 'mutation', 'phylogenetic_trees', 'sitesearch', 'build_gpcr', 'construct', 'tools', 'drugs', 'signprot', 'signprot2', 'mutational_landscape', 'contactnetwork', 'seqsign', 'angles', 'hotspots')
INTERNAL_IPS '10.0.2.2'
LANGUAGES [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')]
LANGUAGES_BIDI ['he', 'ar', 'fa', 'ur']
LANGUAGE_CODE 'en-us'
LANGUAGE_COOKIE_AGE None
LANGUAGE_COOKIE_DOMAIN None
LANGUAGE_COOKIE_NAME 'django_language'
LANGUAGE_COOKIE_PATH '/'
LOCALE_PATHS []
LOGGING {'disable_existing_loggers': False, 'formatters': {'verbose': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s] %(message)s'}, 'verbose_low': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s]'}}, 'handlers': {'build': {'class': 'logging.FileHandler', 'filename': 'logs/build.log', 'formatter': 'verbose', 'level': 'DEBUG'}, 'django': {'class': 'logging.FileHandler', 'filename': 'logs/django.log', 'formatter': 'verbose', 'level': 'WARNING'}, 'protwis': {'class': 'logging.FileHandler', 'filename': 'logs/protwis.log', 'formatter': 'verbose', 'level': 'DEBUG'}}, 'loggers': {'build': {'handlers': ['build'], 'level': 'DEBUG'}, 'django': {'handlers': ['django'], 'level': 'WARNING', 'propagate': True}, 'protwis': {'handlers': ['protwis'], 'level': 'DEBUG'}}, 'version': 1}
LOGGING_CONFIG 'logging.config.dictConfig'
LOGIN_REDIRECT_URL '/accounts/profile/'
LOGIN_URL '/accounts/login/'
LOGOUT_REDIRECT_URL None
MANAGERS []
MEDIA_ROOT '/protwis/media/protwis'
MEDIA_URL '/media/'
MESSAGE_STORAGE 'django.contrib.messages.storage.fallback.FallbackStorage'
MIDDLEWARE ('common.middleware.stats.StatsMiddleware', 'debug_toolbar.middleware.DebugToolbarMiddleware', 'django.contrib.sessions.middleware.SessionMiddleware', 'django.middleware.common.CommonMiddleware', 'django.middleware.csrf.CsrfViewMiddleware', 'django.contrib.auth.middleware.AuthenticationMiddleware', 'django.contrib.messages.middleware.MessageMiddleware', 'django.middleware.clickjacking.XFrameOptionsMiddleware')
MIGRATION_MODULES {}
MONTH_DAY_FORMAT 'F j'
NUMBER_GROUPING 0
PASSWORD_HASHERS '********************'
PASSWORD_RESET_TIMEOUT_DAYS '********************'
PREPEND_WWW False
REFERENCE_POSITIONS {'D1S1': 'D1S1x50', 'D1S2': 'D1S2x50', 'D1T1': 'D1T1x50', 'D1e1': 'D1e1x50', 'ECL1': '23x50', 'ECL2': '45x50', 'H8': '8x50', 'ICL1': '12x50', 'ICL2': '34x50', 'TM1': '1x50', 'TM2': '2x50', 'TM3': '3x50', 'TM4': '4x50', 'TM5': '5x50', 'TM6': '6x50', 'TM7': '7x50'}
ROOT_URLCONF 'protwis.urls'
SECRET_KEY '********************'
SECURE_BROWSER_XSS_FILTER False
SECURE_CONTENT_TYPE_NOSNIFF False
SECURE_HSTS_INCLUDE_SUBDOMAINS False
SECURE_HSTS_PRELOAD False
SECURE_HSTS_SECONDS 0
SECURE_PROXY_SSL_HEADER None
SECURE_REDIRECT_EXEMPT []
SECURE_SSL_HOST None
SECURE_SSL_REDIRECT False
SERVER_EMAIL 'root@localhost'
SESSION_CACHE_ALIAS 'default'
SESSION_COOKIE_AGE 86400
SESSION_COOKIE_DOMAIN None
SESSION_COOKIE_HTTPONLY True
SESSION_COOKIE_NAME 'sessionid'
SESSION_COOKIE_PATH '/'
SESSION_COOKIE_SAMESITE 'Lax'
SESSION_COOKIE_SECURE False
SESSION_ENGINE 'django.contrib.sessions.backends.db'
SESSION_EXPIRE_AT_BROWSER_CLOSE False
SESSION_FILE_PATH None
SESSION_SAVE_EVERY_REQUEST False
SESSION_SERIALIZER 'django.contrib.sessions.serializers.PickleSerializer'
SETTINGS_MODULE 'protwis.settings'
SHORT_DATETIME_FORMAT 'm/d/Y P'
SHORT_DATE_FORMAT 'm/d/Y'
SIGNING_BACKEND 'django.core.signing.TimestampSigner'
SILENCED_SYSTEM_CHECKS []
SITE_NAME 'gpcr'
SITE_TITLE 'GPCRdb'
STATICFILES_DIRS ('/home/protwis/gpcrdb_test/static',)
STATICFILES_FINDERS ['django.contrib.staticfiles.finders.FileSystemFinder', 'django.contrib.staticfiles.finders.AppDirectoriesFinder']
STATICFILES_STORAGE 'django.contrib.staticfiles.storage.StaticFilesStorage'
STATIC_ROOT '/home/protwis/static_test/'
STATIC_URL '/static/'
SWAGGER_SETTINGS {'USE_SESSION_AUTH': False}
TEMPLATES [{'APP_DIRS': True, 'BACKEND': 'django.template.backends.django.DjangoTemplates', 'DIRS': [], 'OPTIONS': {'context_processors': ['django.contrib.auth.context_processors.auth', 'django.template.context_processors.debug', 'django.template.context_processors.i18n', 'django.template.context_processors.media', 'django.template.context_processors.static', 'django.template.context_processors.tz', 'django.contrib.messages.context_processors.messages', 'protwis.context_processors.current_site', 'protwis.context_processors.canonical_tag', 'protwis.context_processors.documentation_url', 'protwis.context_processors.google_analytics', 'protwis.context_processors.site_title'], 'debug': True}}]
TEST_NON_SERIALIZED_APPS []
TEST_RUNNER 'django.test.runner.DiscoverRunner'
THOUSAND_SEPARATOR ','
TIME_FORMAT 'P'
TIME_INPUT_FORMATS ['%H:%M:%S', '%H:%M:%S.%f', '%H:%M']
TIME_ZONE 'Europe/Copenhagen'
USE_I18N True
USE_L10N True
USE_THOUSAND_SEPARATOR False
USE_TZ True
USE_X_FORWARDED_HOST False
USE_X_FORWARDED_PORT False
WSGI_APPLICATION None
X_FRAME_OPTIONS 'SAMEORIGIN'
YEAR_MONTH_FORMAT 'F Y'

Headers

Request headers

Key Value
Accept text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8
Accept-Encoding br,gzip
Accept-Language en-US,en;q=0.5
Connection close
Host test.gpcrdb.org
User-Agent CCBot/2.0 (https://commoncrawl.org/faq/)
X-Forwarded-For 3.236.207.90
X-Forwarded-Proto https
X-Real-Ip 3.236.207.90

Response headers

Key Value
Content-Length 574221
Content-Type text/html; charset=utf-8
Vary Cookie
X-Frame-Options SAMEORIGIN

WSGI environ

Since the WSGI environ inherits the environment of the server, only a significant subset is shown below.

Key Value
PATH_INFO /mutational_landscape/protein/5HT6R_human/
QUERY_STRING
REMOTE_ADDR
REQUEST_METHOD GET
SCRIPT_NAME
SERVER_NAME test.gpcrdb.org
SERVER_PORT 443
SERVER_PROTOCOL HTTP/1.0
SERVER_SOFTWARE gunicorn/19.9.0

Request

View information

View function Arguments Keyword arguments URL name
mutational_landscape.views.render_variants () {'protein': '5HT6R_human'} render

No cookies

No session data

No GET data

No POST data

SQL queries from 1 connection

  •   default 242.42 ms (23 queries including 14 similar and 4 duplicates )
  Query Timeline Time (ms) Action
  +
SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = '5ht6r_human'
1.057069768768447%
 2.56

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89)
  proteins.append(Protein.objects.get(entry_name=protein.lower()))
  +
SELECT ••• "residue_position_set"."id", "residue_position_set"."name", "residue_position_set"."set_type", "residue_position_set"."protein_group" FROM "residue_position_set" WHERE "residue_position_set"."name" = 'State (micro-)switches'
  3 similar queries.
0.24528582092561468%
 0.59

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(128)
  micro_switches_rset = ResiduePositionSet.objects.get(name="State (micro-)switches")
  +
SELECT ••• "residue_generic_number_equivalent"."id", "residue_generic_number_equivalent"."default_generic_number_id", "residue_generic_number_equivalent"."scheme_id", "residue_generic_number_equivalent"."label" FROM "residue_generic_number_equivalent" INNER JOIN "residue_position_set_residue_position" ON ("residue_generic_number_equivalent"."id" = "residue_position_set_residue_position"."residuegenericnumberequivalent_id") WHERE "residue_position_set_residue_position"."residuepositionset_id" = 2
  3 similar queries.
0.7318250976373291%
 1.77

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(130)
  for residue in micro_switches_rset.residue_position.all():
  +
SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" INNER JOIN "residue_generic_number" ON ("residue"."generic_number_id" = "residue_generic_number"."id") INNER JOIN "protein_conformation" ON ("residue"."protein_conformation_id" = "protein_conformation"."id") WHERE ("residue_generic_number"."label" IN ('5x47', '5x50', '6x30', '6x44', '6x50', '6x48', '6x34', '5x58', '3x40', '3x49', '3x50', '7x53', '7x50', '7x49', '7x43') AND "protein_conformation"."protein_id" = 11) ORDER BY "residue"."sequence_number" ASC
  2 similar queries.   Duplicated 2 times.
3.6065080406344387%
 8.74

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(135)
  for ms in ms_object:
  +
SELECT ••• "residue_position_set"."id", "residue_position_set"."name", "residue_position_set"."set_type", "residue_position_set"."protein_group" FROM "residue_position_set" WHERE "residue_position_set"."name" = 'Sodium ion pocket'
  3 similar queries.
0.14211628357558667%
 0.34

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(139)
  sodium_pocket_rset = ResiduePositionSet.objects.get(name="Sodium ion pocket")
  +
SELECT ••• "residue_generic_number_equivalent"."id", "residue_generic_number_equivalent"."default_generic_number_id", "residue_generic_number_equivalent"."scheme_id", "residue_generic_number_equivalent"."label" FROM "residue_generic_number_equivalent" INNER JOIN "residue_position_set_residue_position" ON ("residue_generic_number_equivalent"."id" = "residue_position_set_residue_position"."residuegenericnumberequivalent_id") WHERE "residue_position_set_residue_position"."residuepositionset_id" = 3
  3 similar queries.
0.4356921358061239%
 1.06

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(141)
  for residue in sodium_pocket_rset.residue_position.all():
  +
SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" INNER JOIN "residue_generic_number" ON ("residue"."generic_number_id" = "residue_generic_number"."id") INNER JOIN "protein_conformation" ON ("residue"."protein_conformation_id" = "protein_conformation"."id") WHERE ("residue_generic_number"."label" IN ('5x47', '5x50', '6x30', '6x44', '6x50', '6x48', '6x34', '5x58', '3x40', '3x49', '3x50', '7x53', '7x50', '7x49', '7x43') AND "protein_conformation"."protein_id" = 11) ORDER BY "residue"."sequence_number" ASC
  2 similar queries.   Duplicated 2 times.
0.5004066787768755%
 1.21

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(146)
  for sp in sp_object:
  +
SELECT ••• "residue_ptm"."id", "residue_ptm"."protein_id", "residue_ptm"."residue_id", "residue_ptm"."modification" FROM "residue_ptm" WHERE "residue_ptm"."protein_id" IN (11)
0.2451874705563582%
 0.59

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(149)
  for ptm in ptms:
  +
SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" WHERE "residue"."id" IN (13201, 13338, 13334, 13423) ORDER BY "residue"."sequence_number" ASC
0.7940808813766692%
 1.92

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(149)
  for ptm in ptms:
  +
SELECT ••• "residue_position_set"."id", "residue_position_set"."name", "residue_position_set"."set_type", "residue_position_set"."protein_group" FROM "residue_position_set" WHERE "residue_position_set"."name" = 'G-protein interface'
  3 similar queries.
0.15726224044108175%
 0.38

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(154)
  rset = ResiduePositionSet.objects.get(name='G-protein interface')
  +
SELECT ••• "residue_generic_number_equivalent"."id", "residue_generic_number_equivalent"."default_generic_number_id", "residue_generic_number_equivalent"."scheme_id", "residue_generic_number_equivalent"."label" FROM "residue_generic_number_equivalent" INNER JOIN "residue_position_set_residue_position" ON ("residue_generic_number_equivalent"."id" = "residue_position_set_residue_position"."residuegenericnumberequivalent_id") WHERE "residue_position_set_residue_position"."residuepositionset_id" = 1
  3 similar queries.
0.4298894640199926%
 1.04

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(156)
  for residue in rset.residue_position.all():
  +
SELECT ••• "protein_family"."id", "protein_family"."parent_id", "protein_family"."slug", "protein_family"."name" FROM "protein_family" WHERE "protein_family"."id" = 16
0.23171346996822298%
 0.56

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(163)
  orthologs = Protein.objects.filter(family__slug=proteins[0].family.slug, sequence_type__slug='wt')
  +
SELECT ••• "interaction_residue_fragment"."id", "interaction_residue_fragment"."structure_ligand_pair_id", "interaction_residue_fragment"."rotamer_id", "interaction_residue_fragment"."fragment_id", "interaction_residue_fragment"."interaction_type_id" FROM "interaction_residue_fragment" INNER JOIN "interaction_structure_ligand" ON ("interaction_residue_fragment"."structure_ligand_pair_id" = "interaction_structure_ligand"."id") INNER JOIN "structure" ON ("interaction_structure_ligand"."structure_id" = "structure"."id") INNER JOIN "protein_conformation" ON ("structure"."protein_conformation_id" = "protein_conformation"."id") INNER JOIN "protein" ON ("protein_conformation"."protein_id" = "protein"."id") INNER JOIN "interaction_type_residue_fragment" ON ("interaction_residue_fragment"."interaction_type_id" = "interaction_type_residue_fragment"."id") WHERE ("interaction_structure_ligand"."annotated" = true AND "protein"."parent_id" IN (SELECT ••• U0."id" FROM "protein" U0 INNER JOIN "protein_family" U1 ON (U0."family_id" = U1."id") INNER JOIN "protein_sequence_type" U2 ON (U0."sequence_type_id" = U2."id") WHERE (U1."slug" = '001_001_001_012' AND U2."slug" = 'wt')) AND NOT ("interaction_type_residue_fragment"."type" = 'hidden' AND "interaction_type_residue_fragment"."type" IS NOT NULL))
84.88335154454337%
 205.77

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(170)
  for interaction in interactions:
  +
SELECT ••• "mutation_natural"."id", "mutation_natural"."protein_id", "mutation_natural"."residue_id", "mutation_natural"."amino_acid", "mutation_natural"."type", "mutation_natural"."allele_frequency", "mutation_natural"."allele_count", "mutation_natural"."allele_number", "mutation_natural"."number_homozygotes", "mutation_natural"."sift_score", "mutation_natural"."polyphen_score" FROM "mutation_natural" WHERE "mutation_natural"."protein_id" IN (11)
1.8755415417207182%
 4.55

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(190)
  for NM in NMs:
  +
SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" WHERE "residue"."id" IN (13319, 13320, 13321, 13324, 13330, 13331, 13333, 13335, 13337, 13345, 13360, 13364, 13366, 13368, 13369, 13371, 13372, 13374, 13375, 13379, 13383, 13385, 13386, 13387, 13390, 13391, 13396, 13398, 13400, 13401, 13405, 13406, 13408, 13412, 13413, 13415, 13417, 13418, 13420, 13426, 13427, 13430, 13431, 13437, 13440, 13441, 13443, 13447, 13451, 13452, 13453, 13456, 13460, 13464, 13466, 13469, 13471, 13476, 13478, 13480, 13483, 13484, 13486, 13487, 13490, 13491, 13493, 13494, 13496, 13499, 13500, 13502, 13504, 13505, 13507, 13508, 13509, 13510, 13515, 13079, 13082, 13084, 13085, 13091, 13092, 13093, 13094, 13095, 13100, 13102, 13103, 13105, 13106, 13110, 13112, 13119, 13121, 13122, 13123, 13124, 13125, 13129, 13131, 13138, 13140, 13143, 13145, 13155, 13163, 13165, 13166, 13167, 13172, 13179, 13185, 13186, 13188, 13191, 13194, 13196, 13197, 13202, 13212, 13214, 13219, 13221, 13227, 13230, 13244, 13248, 13249, 13250, 13257, 13259, 13266, 13269, 13278, 13280, 13285, 13292, 13296, 13297, 13302, 13303, 13304, 13306, 13307) ORDER BY "residue"."sequence_number" ASC
0.9734719549004546%
 2.36

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(190)
  for NM in NMs:
  +
SELECT ••• "residue_generic_number"."id", "residue_generic_number"."scheme_id", "residue_generic_number"."protein_segment_id", "residue_generic_number"."label" FROM "residue_generic_number" WHERE "residue_generic_number"."id" IN (88576, 44673, 29058, 34050, 48001, 2, 87809, 87176, 10, 83467, 74380, 79480, 12, 93066, 70419, 92307, 61080, 410, 27, 8606, 16414, 6942, 10270, 3230, 2079, 24990, 32802, 36130, 42146, 85164, 25005, 91437, 94253, 80949, 14334, 57400, 82746, 13502, 23742, 7358, 26174, 31554, 36546, 45505, 82370, 87493, 88894, NULL, 596, 70613, 71509, 56152, 61912, 66904, 68568, 7774, 11102, 6110, 20446, 98, 15582, 31970, 35298, 38626, 42722, 68964, 81632, 83810, 92526, 70898, 91122, 94078, 24574, 63992, 86651, 53500, 8190)
  2 similar queries.
0.42851255885040224%
 1.04

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(190)
  for NM in NMs:
  +
SELECT ••• "residue_generic_number"."id", "residue_generic_number"."scheme_id", "residue_generic_number"."protein_segment_id", "residue_generic_number"."label" FROM "residue_generic_number" WHERE "residue_generic_number"."id" IN (81664, 83841, 32002, 35330, 38658, 42755, 66936, 68995, 92552, 86668, 87826, 64024, 79512, 87193, 88601, 94104, 14366, 8222, 32, 928, 2464, 24606, 29090, 34082, 44705, 48033, 74409, 83498, 93099, 91181, 53553, 94257, 92339, 56184, 6142, 61112, 68600, 572, 8638, 16446, 6974, 10302, 3262, 25022, 32834, 36162, 42178, 70469, 91462, 85196, NULL, 11134, 80979, 88916, 57432, 82778, 25051, 70910, 90330, 23774, 7390, 13534, 45537, 31586, 36578, 49249, 82402, 87519, 61944, 70633, 7806, 118, 20478, 26230, 71545, 90874, 15614)
  2 similar queries.
0.36094585517121325%
 0.87

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(190)
  for NM in NMs:
  +
SELECT ••• "protein_segment"."id", "protein_segment"."slug", "protein_segment"."name", "protein_segment"."category", "protein_segment"."fully_aligned", "protein_segment"."partial", "protein_segment"."proteinfamily" FROM "protein_segment" WHERE "protein_segment"."id" IN (1, 5, 6, 7, 8, 10, 11, 12, 13, 14, 15, 16, 17, 18, 20, 21) ORDER BY "protein_segment"."id" ASC
  2 similar queries.   Duplicated 2 times.
0.32465456891557903%
 0.79

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(190)
  for NM in NMs:
  +
SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."id" IN (11)
0.17486695653798834%
 0.42

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(190)
  for NM in NMs:
  +
SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" INNER JOIN "protein_conformation" ON ("residue"."protein_conformation_id" = "protein_conformation"."id") WHERE "protein_conformation"."protein_id" = 11 ORDER BY "residue"."sequence_number" ASC
0.5630558639932414%
 1.36

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(237)
  for r in residuelist:
  +
SELECT ••• "protein_segment"."id", "protein_segment"."slug", "protein_segment"."name", "protein_segment"."category", "protein_segment"."fully_aligned", "protein_segment"."partial", "protein_segment"."proteinfamily" FROM "protein_segment" WHERE "protein_segment"."id" IN (1, 5, 6, 7, 8, 10, 11, 12, 13, 14, 15, 16, 17, 18, 20, 21) ORDER BY "protein_segment"."id" ASC
  2 similar queries.   Duplicated 2 times.
0.2155840094101633%
 0.52

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(237)
  for r in residuelist:
  +
SELECT ••• "residue_generic_number"."id", "residue_generic_number"."scheme_id", "residue_generic_number"."protein_segment_id", "residue_generic_number"."label" FROM "residue_generic_number" WHERE "residue_generic_number"."id" IN (47617, 28674, 35330, 49665, 71172, 88068, 90119, 90635, 64024, 25625, 88601, 24606, 8222, 32, 2080, 14366, 30754, 37410, 43043, 79903, 85541, 93630, 83498, 52781, 84575, 91181, 94257, 66104, 68600, 572, 10302, 16446, 18494, 45121, 32834, 39490, 41026, 51265, 55379, 80979, 77399, 26200, 57432, 59480, 61528, 68184, 22110, 20062, 3678, 5726, 28258, 34914, 47201, 49249, 53859, 70752, 82022, 89186, 118, 4094, 20478, 26230, 63608, 69245, 13950, 7806, 24190, 30338, 36994, 41602, 72323, 73356, 86668, 65688, 79512, 87193, 78491, 92829, 16030, 9886, 1696, 18078, 11422, 32418, 39074, 44705, 75426, 76446, 74409, 70315, 52403, 92339, 54965, 22526, 93876, 57016, 59064, 61112, 67768, 5310, 3262, 21694, 46785, 27842, 34498, 42178, 50882, 85196, 93390, 80591, 63192, 89816, 90330, 19678, 23774, 224, 7390, 29922, 11998, 13534, 36578, 48865, 84193, 91871, 83178, 65272, 90874, 9470, 17662, 15614, 44289, 32002, 38658, 42755, 70910, 71935, 81664, 86285, 54546, 87826, 88343, 25368, 56600, 58648, 60696, 67352, 4894, 2847, 1312, 46369, 27426, 34082, 40738, 53534, 77091, 79141, 59896, 53553, 78131, 25912, 62776, 52026, 74041, 19262, 23358, 6974, 13118, 21310, 29506, 36162, 48449, 50498, 70469, 69960, 75076, 91462, NULL, 88916, 64856, 82778, 9054, 15198, 43873, 31586, 38242, 41314, 73062, 61944, 80234, 54127, 89457, 12286, 56184, 60280, 66936, 71545, 86907, 17278, 11134, 4478, 45953, 27010, 33666, 40322, 68995, 83841, 92552, 76096, 58264, 62360, 94104, 81307, 6558, 12702, 928, 2464, 20894, 29090, 22942, 35746, 41890, 48033, 50081, 93099, 53164, 64440, 85944, 91578, 51645, 18878, 8638, 11710, 14782, 31170, 25022, 37826, 43459, 77766, 78791, 76744, 84933, 66520, 75738, 25051, 73692, 92123, 10718, 16862, 87519, 45537, 26594, 33250, 39906, 42467, 69603, 82402, 55785, 70633, 74732, 91126, 53239, 57848, 72701, 6142)
  2 similar queries.
0.8208321818144267%
 1.99

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(237)
  for r in residuelist:
  +
SELECT ••• "residue_generic_number"."id", "residue_generic_number"."scheme_id", "residue_generic_number"."protein_segment_id", "residue_generic_number"."label" FROM "residue_generic_number" WHERE "residue_generic_number"."id" IN (88576, 30722, 37378, 43010, 2, 6, 7, 4, 79876, 85510, 83467, 9, 10, 11, 15, 16, 17, 18, 19, 20, 12, 13, 66072, 27, 16414, 2079, 10270, 18462, 32802, 39458, 40994, 45089, 52780, 94253, 53806, 55347, 80949, 77366, 26168, 57400, 59448, 61496, 68152, 3646, 5694, 22078, 26174, 28226, 34882, 47169, 51266, 70718, 81989, 84547, 596, 89174, 63576, 24158, 7774, 13918, 69216, 30306, 98, 36962, 41570, 72295, 73322, 65656, 79480, 86651, 78461, 9854, 18046, 11390, 15998, 32386, 39042, 44673, 75396, 76414, 92800, 87176, 74380, 54927, 70290, 92307, 56984, 59032, 61080, 67736, 88056, 93849, 5278, 3230, 1695, 46753, 27810, 34466, 42146, 85164, 80559, 93361, 52404, 183, 63160, 89785, 23742, 7358, 11966, 13502, 19646, 29890, 36546, 48833, 50881, 91838, 83146, 84171, 65240, 25307, 71900, 9438, 15582, 81632, 44257, 31970, 38626, 42722, 54507, 70898, 86259, 8190, 24574, 56568, 60664, 67320, 53500, 4862, 46337, 27394, 34050, 40706, 87809, 88322, 70419, 77076, 78102, 74007, 25880, 62744, 6942, 13086, 21278, 1313, 29474, 23326, 36130, 48417, 50466, 50465, 75046, 76072, 91437, 69937, 64824, 82746, 52027, 9022, 15166, 88894, 43841, 31554, 38210, 41282, 54087, 73034, NULL, 80210, 71509, 56152, 66904, 89432, 86875, 11102, 17246, 45921, 26978, 33634, 40290, 68964, 83810, 92526, 58232, 62328, 12670, 20862, 22910, 6526, 29058, 35714, 41858, 48001, 50049, 94078, 93066, 81293, 64408, 85912, 410, 11678, 2463, 8606, 929, 24990, 31138, 14750, 37794, 43426, 63992, 78761, 76714, 77739, 91563, 25005, 53165, 84911, 93615, 66488, 51642, 10686, 16830, 75712, 45505, 33218, 39874, 42434, 69573, 82370, 53191, 87493, 92098, 73674, 55758, 74704, 70613, 26584, 57816, 59864, 61912, 68568, 72668, 22494, 20446, 4062, 6110, 12254, 28642, 35298, 47585, 49633, 71138, 91122, 25592, 14334)
  2 similar queries.
0.802145611655699%
 1.94

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(237)
  for r in residuelist:

Static files (590 found, 40 used)

Static file path

  1. /home/protwis/gpcrdb_test/static

Static file apps

  1. django.contrib.admin
  2. debug_toolbar
  3. rest_framework
  4. rest_framework_swagger
  5. polymorphic

Static files

bootstrap/css/bootstrap.min.css
/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-submenu.min.css
/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
home/css/jquery-ui.min.css
/home/protwis/gpcrdb_test/static/home/css/jquery-ui.min.css
home/css/jquery-ui.theme.min.css
/home/protwis/gpcrdb_test/static/home/css/jquery-ui.theme.min.css
home/css/bootstrap-treeview.min.css
/home/protwis/gpcrdb_test/static/home/css/bootstrap-treeview.min.css
home/css/style.css
/home/protwis/gpcrdb_test/static/home/css/style.css
flowplayer/flowplayer.css
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
home/css/cookieconsent.min.css
/home/protwis/gpcrdb_test/static/home/css/cookieconsent.min.css
home/css/jquery.dataTables.min.css
/home/protwis/gpcrdb_test/static/home/css/jquery.dataTables.min.css
home/css/structure_browser.css
/home/protwis/gpcrdb_test/static/home/css/structure_browser.css
home/css/residue_table.css
/home/protwis/gpcrdb_test/static/home/css/residue_table.css
home/css/alignment.css
/home/protwis/gpcrdb_test/static/home/css/alignment.css
/home/protwis/gpcrdb_test/static
home/css/mainmenu.css
/home/protwis/gpcrdb_test/static/home/css/mainmenu.css
home/css/modal.css
/home/protwis/gpcrdb_test/static/home/css/modal.css
home/css/jquery.powertip.css
/home/protwis/gpcrdb_test/static/home/css/jquery.powertip.css
home/js/jquery-3.1.1.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/citation_tool.js
/home/protwis/gpcrdb_test/static/home/js/citation_tool.js
home/js/joinus_tool.js
/home/protwis/gpcrdb_test/static/home/js/joinus_tool.js
home/js/jquery-3.1.1.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/jquery-ui.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery-ui.min.js
bootstrap/js/bootstrap.min.js
/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/js/bootstrap-submenu.js
/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
home/js/navbar-autocomplete.js
/home/protwis/gpcrdb_test/static/home/js/navbar-autocomplete.js
home/js/svg-pan-zoom.min.js
/home/protwis/gpcrdb_test/static/home/js/svg-pan-zoom.min.js
home/js/bootstrap-treeview.min.js
/home/protwis/gpcrdb_test/static/home/js/bootstrap-treeview.min.js
home/js/papaparse.min.js
/home/protwis/gpcrdb_test/static/home/js/papaparse.min.js
flowplayer/flowplayer.min.js
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.min.js
flowplayer/flowplayer.overlay.min.js
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.min.js
flowplayer/flowplayer.overlay.bootstrap.js
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.bootstrap.js
home/js/gpcrdb.js
/home/protwis/gpcrdb_test/static/home/js/gpcrdb.js
home/js/cookieconsent.min.js
/home/protwis/gpcrdb_test/static/home/js/cookieconsent.min.js
home/js/jquery.dataTables.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.min.js
home/js/dataTables.tableTools.min.js
/home/protwis/gpcrdb_test/static/home/js/dataTables.tableTools.min.js
home/js/jquery.dataTables.columnFilter.js
/home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.columnFilter.js
home/js/selection.js
/home/protwis/gpcrdb_test/static/home/js/selection.js
home/js/saveSvgAsPng.js
/home/protwis/gpcrdb_test/static/home/js/saveSvgAsPng.js
home/js/alignment.js
/home/protwis/gpcrdb_test/static/home/js/alignment.js
home/js/diagrams.js
/home/protwis/gpcrdb_test/static/home/js/diagrams.js
home/js/residuetable.js
/home/protwis/gpcrdb_test/static/home/js/residuetable.js

django.contrib.staticfiles.finders.FileSystemFinder (415 files)

Path Location
visualization_scripts/maestro_label_generic_numbers.py /home/protwis/gpcrdb_test/static/visualization_scripts/maestro_label_generic_numbers.py
visualization_scripts/pymol_view_generic_numbers.pml /home/protwis/gpcrdb_test/static/visualization_scripts/pymol_view_generic_numbers.pml
bootstrap/js/npm.js /home/protwis/gpcrdb_test/static/bootstrap/js/npm.js
bootstrap/js/bootstrap.js /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.js
bootstrap/js/bootstrap-submenu.js /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
bootstrap/js/bootstrap.min.js /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/fonts/glyphicons-halflings-regular.eot /home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.eot
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bootstrap/fonts/glyphicons-halflings-regular.woff2 /home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff2
bootstrap/css/bootstrap.css.map /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css.map
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bootstrap/css/bootstrap-theme.css /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css
bootstrap/css/bootstrap-theme.min.css /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css
blast/protwis_blastdb.psq /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psq
blast/protwis_human_bundle_blastdb.pin /home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pin
blast/protwis_blastdb.pin /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pin
blast/protwis_human_blastdb.phr /home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.phr
blast/protwis_blastdb.psd /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psd
blast/protwis_blastdb.phr /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.phr
blast/protwis_human_blastdb.psq /home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psq
blast/protwis_human_gpcr_blastdb.phr /home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.phr
blast/protwis_human_gpcr_blastdb.psq /home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psq
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blast/.gitignore /home/protwis/gpcrdb_test/static/blast/.gitignore
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blast/protwis_blastdb.pog /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pog
blast/protwis_gpcr_blastdb.psq /home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psq
blast/protwis_human_gpcr_blastdb.psi /home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psi
blast/protwis_gpcr_blastdb.pin /home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.pin
blast/protwis_human_bundle_blastdb.pog /home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pog
blast/protwis_human_gpcr_blastdb.pog /home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.pog
blast/protwis_blastdb.psi /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psi
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blast/protwis_human_bundle_blastdb.psq /home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.psq
blast/protwis_gpcr_blastdb.pog /home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.pog
blast/protwis_human_blastdb.psi /home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psi
blast/protwis_human_gpcr_blastdb.pin /home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.pin
blast/protwis_gpcr_blastdb.psi /home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psi
blast/protwis_gpcr_blastdb.phr /home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.phr
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blast/protwis_human_bundle_blastdb.phr /home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.phr
flowplayer/flowplayer.min.js /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.min.js
flowplayer/flowplayer.css /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
flowplayer/flowplayer.overlay.min.js /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.min.js
flowplayer/flowplayer.overlay.bootstrap.js /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.bootstrap.js
flowplayer/fonts/fpicons.ttf /home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.ttf
flowplayer/fonts/fpicons.woff /home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.woff
flowplayer/fonts/fpicons.svg /home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.svg
flowplayer/fonts/fpicons.eot /home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.eot
flowplayer/img/play_white.png /home/protwis/gpcrdb_test/static/flowplayer/img/play_white.png
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flowplayer/img/playful_white.png /home/protwis/gpcrdb_test/static/flowplayer/img/playful_white.png
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home/images/Class_C_crystallized.svg /home/protwis/gpcrdb_test/static/home/images/Class_C_crystallized.svg
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home/images/004_tree.xml /home/protwis/gpcrdb_test/static/home/images/004_tree.xml
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home/images/glyphicons-halflings-white.png /home/protwis/gpcrdb_test/static/home/images/glyphicons-halflings-white.png
home/images/Other_crystallized.svg /home/protwis/gpcrdb_test/static/home/images/Other_crystallized.svg
home/images/loading.gif /home/protwis/gpcrdb_test/static/home/images/loading.gif
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home/images/copy_hover.png /home/protwis/gpcrdb_test/static/home/images/copy_hover.png
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home/css/mainmenu.css /home/protwis/gpcrdb_test/static/home/css/mainmenu.css
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home/css/button_spinner.css /home/protwis/gpcrdb_test/static/home/css/button_spinner.css
home/css/targetselect_functions.css /home/protwis/gpcrdb_test/static/home/css/targetselect_functions.css
home/css/flareplot-contactbrowser.css /home/protwis/gpcrdb_test/static/home/css/flareplot-contactbrowser.css
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home/css/unitip.css /home/protwis/gpcrdb_test/static/home/css/unitip.css
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home/css/phylo.css /home/protwis/gpcrdb_test/static/home/css/phylo.css
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django.contrib.staticfiles.finders.AppDirectoriesFinder (175 files)

Path Location
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admin/js/popup_response.js /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/popup_response.js
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admin/js/calendar.js /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/calendar.js
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admin/js/jquery.init.js /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/jquery.init.js
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admin/js/inlines.js /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/inlines.js
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admin/js/change_form.js /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/change_form.js
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Templates (9 rendered)

Template paths

None

Templates

browser.html
/home/protwis/gpcrdb_test/mutational_landscape/templates/browser.html
Toggle context {'False': False, 'None': None, 'True': True} {'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'ERROR': 40, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30}, 'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), 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