GPCRdb

Variation Browser

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Receptor	Position	GPCRdb	Segment	Variant	Mutation type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation


Receptor	Position	GPCRdb	Segment	Variant	Mutation Type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation
aa2ar_human	28	1.54x54	TM1	C => ValfsTer74	frameshift	1.655e-05	2	120810	0	None	None
aa2ar_human	138	4.59x59	TM4	T => SerfsTer31	frameshift	8.433e-06	1	118582	0	None	None
aa2ar_human	179	5.40x411	TM5	Y => GlufsTer156	frameshift	8.238e-06	1	121388	0	None	None
aa2ar_human	197	5.58x58	TM5	Y => LeufsTer134	frameshift	8.237e-06	1	121398	0	None	None	SodiumPocket MicroSwitch
aa2ar_human	206	5.67x67	TM5	R => Ter	stop gained	1.648e-05	2	121378	0	None	None	GP (contact)
aa2ar_human	382		C-term	D => ArgfsTer6	frameshift	1.971e-05	2	101496	0	None	None
aa2ar_human	412		C-term	S => LeufsTer36	frameshift	1.984e-05	2	100828	0	None	None
aa2ar_human	4	1.30x30	TM1	M => T	missense	0.0001264	10	79096	0	nan	0.0
aa2ar_human	6	1.32x32	TM1	S => F	missense	1.138e-05	1	87846	0	0.06	0.005
aa2ar_human	7	1.33x33	TM1	S => L	missense	1.084e-05	1	92226	0	0.26	0.0
aa2ar_human	8	1.34x34	TM1	V => A	missense	1.998e-05	2	100104	0	nan	0.002
aa2ar_human	15	1.41x41	TM1	A => T	missense	8.653e-05	10	115572	0	nan	0.004
aa2ar_human	21	1.47x47	TM1	I => V	missense	3.34e-05	4	119762	0	nan	0.0
aa2ar_human	23	1.49x49	TM1	G => D	missense	8.312e-06	1	120308	0	0.0	1.0
aa2ar_human	24	1.50x50	TM1	N => S	missense	8.296e-06	1	120538	0	0.0	0.99
aa2ar_human	28	1.54x54	TM1	C => S	missense	8.271e-06	1	120902	0	0.0	0.567
aa2ar_human	33	1.59x59	TM1	L => R	missense	8.255e-06	1	121132	0	0.03	0.002
aa2ar_human	40	2.38x38	TM2	V => I	missense	0.0001897	23	121232	0	0.21	0.038
aa2ar_human	49	2.47x47	TM2	A => V	missense	4.129e-05	5	121102	0	0.0	0.999
aa2ar_human	50	2.48x48	TM2	A => V	missense	0.00253	306	120926	7	1.0	0.0
aa2ar_human	52	2.50x50	TM2	D => N	missense	8.255e-06	1	121142	0	0.0	1.0
aa2ar_human	54	2.52x52	TM2	A => T	missense	8.254e-06	1	121152	0	0.01	0.893
aa2ar_human	59	2.57x56	TM2	A => T	missense	8.252e-06	1	121190	0	0.0	0.33
aa2ar_human	60	2.58x57	TM2	I => V	missense	8.25e-06	1	121210	0	0.06	0.039
aa2ar_human	66	2.64x63	TM2	I => V	missense	8.247e-06	1	121258	0	0.05	0.063	LB (hydrophobic)
aa2ar_human	67	2.65x64	TM2	S => R	missense	8.246e-06	1	121268	0	0.0	0.672	LB (polar (hydrogen bond))
aa2ar_human	68	2.66x65	TM2	T => I	missense	8.246e-06	1	121270	0	0.33	0.001
aa2ar_human	69	2.67x66	TM2	G => R	missense	1.649e-05	2	121274	0	0.0	0.996
aa2ar_human	72	23.52x52	ECL1	A => T	missense	2.474e-05	3	121270	0	0.68	0.028
aa2ar_human	72	23.52x52	ECL1	A => V	missense	8.245e-06	1	121284	0	0.25	0.047
aa2ar_human	88	3.36x36	TM3	T => R	missense	1.649e-05	2	121322	0	0.0	0.999	LB (polar (hydrogen bond))
aa2ar_human	89	3.37x37	TM3	Q => H	missense	8.242e-06	1	121326	0	0.0	0.932
aa2ar_human	102	3.50x50	TM3	R => H	missense	8.263e-06	1	121024	0	0.0	1.0	SodiumPocket MicroSwitch GP (contact)
aa2ar_human	105	3.53x53	TM3	A => T	missense	8.287e-06	1	120670	0	0.04	0.447	GP (contact)
aa2ar_human	107	3.55x55	TM3	R => C	missense	1.665e-05	2	120156	0	0.01	0.007	GP (contact)
aa2ar_human	111	34.52x52	ICL2	R => W	missense	8.457e-06	1	118246	0	0.0	0.636	GP (contact)
aa2ar_human	116	34.57x57	ICL2	V => M	missense	9.016e-06	1	110914	0	0.05	0.697	GP (contact)
aa2ar_human	121	4.42x42	TM4	A => S	missense	8.964e-06	1	111552	0	0.0	0.966
aa2ar_human	123	4.44x44	TM4	G => D	missense	8.929e-06	1	111996	0	0.2	0.579
aa2ar_human	125	4.46x46	TM4	I => T	missense	8.884e-06	1	112566	0	0.0	0.98
aa2ar_human	130	4.51x51	TM4	V => M	missense	3.51e-05	4	113958	0	0.03	0.59
aa2ar_human	136	4.57x57	TM4	G => S	missense	1.702e-05	2	117524	0	0.0	0.977
aa2ar_human	140	4.61x61	TM4	M => I	missense	8.354e-06	1	119696	0	0.01	0.091
aa2ar_human	141	4.62x62	TM4	L => Q	missense	4.171e-05	5	119886	0	0.0	0.947
aa2ar_human	147		ECL2	G => S	missense	0.004117	497	120706	9	1.0	0.001
aa2ar_human	147		ECL2	G => C	missense	2.485e-05	3	120706	0	0.04	0.487
aa2ar_human	148		ECL2	Q => R	missense	4.138e-05	5	120844	0	0.49	0.002
aa2ar_human	156		ECL2	S => T	missense	8.251e-06	1	121200	0	0.33	0.001
aa2ar_human	158		ECL2	G => S	missense	8.247e-06	1	121262	0	1.0	0.001
aa2ar_human	160		ECL2	G => R	missense	0.0001814	22	121292	0	0.5	0.001
aa2ar_human	161		ECL2	E => K	missense	8.243e-06	1	121320	0	0.57	0.001
aa2ar_human	165		ECL2	A => S	missense	2.472e-05	3	121360	0	0.61	0.032
aa2ar_human	174	5.35x37	TM5	M => V	missense	8.238e-06	1	121388	0	0.0	0.508	LB (hydrophobic)
aa2ar_human	179	5.40x411	TM5	Y => H	missense	8.237e-06	1	121404	0	0.0	0.728
aa2ar_human	184	5.45x46	TM5	A => T	missense	8.237e-05	10	121402	0	0.11	0.294
aa2ar_human	186	5.47x47	TM5	V => M	missense	8.237e-06	1	121402	0	0.0	0.912	SodiumPocket MicroSwitch LB (hydrophobic)
aa2ar_human	192	5.53x53	TM5	L => P	missense	8.237e-06	1	121398	0	0.0	0.918
aa2ar_human	199	5.60x60	TM5	R => W	missense	8.238e-06	1	121396	0	0.02	0.055
aa2ar_human	199	5.60x60	TM5	R => Q	missense	2.471e-05	3	121394	0	0.04	0.049
aa2ar_human	203	5.64x64	TM5	A => V	missense	1.648e-05	2	121382	0	1.0	0.109	GP (contact)
aa2ar_human	205	5.66x66	TM5	R => Q	missense	1.648e-05	2	121380	0	0.03	0.598	GP (contact)
aa2ar_human	206	5.67x67	TM5	R => Q	missense	4.119e-05	5	121380	0	0.08	0.052	GP (contact)
aa2ar_human	212	5.73x73	TM5	E => K	missense	8.238e-06	1	121382	0	0.15	0.006
aa2ar_human	215		ICL3	P => L	missense	8.239e-06	1	121380	0	0.38	0.001
aa2ar_human	217		ICL3	P => L	missense	8.239e-06	1	121370	0	0.16	0.025
aa2ar_human	217		ICL3	P => R	missense	8.239e-06	1	121370	0	0.33	0.014
aa2ar_human	220	6.22x22	TM6	R => Q	missense	8.239e-06	1	121378	0	0.09	0.011
aa2ar_human	222	6.24x24	TM6	R => G	missense	8.239e-06	1	121374	0	0.03	0.076
aa2ar_human	222	6.24x24	TM6	R => W	missense	8.239e-06	1	121374	0	0.0	0.971
aa2ar_human	222	6.24x24	TM6	R => Q	missense	8.239e-06	1	121380	0	0.14	0.153
aa2ar_human	228	6.30x30	TM6	E => D	missense	1.648e-05	2	121384	0	0.02	0.519	SodiumPocket MicroSwitch
aa2ar_human	229	6.31x31	TM6	V => I	missense	8.238e-06	1	121384	0	0.41	0.016
aa2ar_human	242	6.44x44	TM6	F => S	missense	8.238e-06	1	121386	0	0.0	1.0	SodiumPocket MicroSwitch
aa2ar_human	249	6.51x51	TM6	L => P	missense	8.238e-06	1	121392	0	0.0	0.997	LB (hydrophobic)
aa2ar_human	261		ECL3	D => N	missense	1.648e-05	2	121384	0	0.5	0.0
aa2ar_human	262		ECL3	C => G	missense	8.238e-06	1	121390	0	0.02	0.238
aa2ar_human	265		ECL3	A => T	missense	8.238e-06	1	121384	0	0.44	0.03
aa2ar_human	270	7.35x34	TM7	M => T	missense	1.648e-05	2	121386	0	0.05	0.5	LB (hydrophobic)
aa2ar_human	273	7.38x37	TM7	A => G	missense	8.239e-06	1	121378	0	0.16	0.008
aa2ar_human	275	7.40x39	TM7	V => I	missense	0.0001895	23	121372	0	1.0	0.001
aa2ar_human	280	7.45x45	TM7	N => S	missense	8.24e-06	1	121362	0	0.0	0.948
aa2ar_human	281	7.46x46	TM7	S => L	missense	8.24e-06	1	121356	0	0.0	1.0
aa2ar_human	290	7.55x55	TM7	Y => F	missense	2.473e-05	3	121312	0	0.42	0.011	GP (contact)
aa2ar_human	291	7.56x56	TM7	R => C	missense	1.649e-05	2	121314	0	0.0	0.977	GP (contact)
aa2ar_human	291	7.56x56	TM7	R => H	missense	8.243e-06	1	121316	0	0.03	0.118	GP (contact)
aa2ar_human	293	8.48x48	H8	R => C	missense	7.419e-05	9	121312	0	0.0	0.936	GP (contact)
aa2ar_human	294	8.49x49	H8	E => D	missense	8.244e-06	1	121304	0	0.43	0.001	GP (contact)
aa2ar_human	295	8.50x50	H8	F => L	missense	8.244e-06	1	121302	0	0.0	0.926
aa2ar_human	296	8.51x51	H8	R => H	missense	2.473e-05	3	121300	0	0.02	0.719	GP (contact)
aa2ar_human	300	8.55x55	H8	R => H	missense	2.474e-05	3	121280	0	0.32	0.001
aa2ar_human	300	8.55x55	H8	R => L	missense	8.245e-06	1	121280	0	0.33	0.011
aa2ar_human	304	8.59x59	H8	R => C	missense	8.249e-06	1	121226	0	0.01	0.014
aa2ar_human	304	8.59x59	H8	R => H	missense	7.425e-05	9	121210	0	0.11	0.001
aa2ar_human	306	8.61x61	H8	H => R	missense	8.253e-06	1	121166	0	0.06	0.001
aa2ar_human	306	8.61x61	H8	H => Q	missense	8.255e-06	1	121136	0	0.03	0.008
aa2ar_human	307	8.62x62	H8	V => I	missense	1.651e-05	2	121134	0	1.0	0.0
aa2ar_human	308	8.63x63	H8	L => P	missense	3.303e-05	4	121108	0	0.0	0.517
aa2ar_human	309	8.64x64	H8	R => K	missense	8.258e-06	1	121090	0	1.0	0.002
aa2ar_human	320		C-term	S => N	missense	8.319e-06	1	120212	0	0.09	0.093
aa2ar_human	329		C-term	S => N	missense	8.433e-06	1	118588	0	0.17	0.002
aa2ar_human	330		C-term	D => G	missense	8.444e-06	1	118430	0	0.14	0.075
aa2ar_human	331		C-term	G => R	missense	3.383e-05	4	118224	0	0.2	0.054
aa2ar_human	334		C-term	V => I	missense	1.703e-05	2	117410	0	0.58	0.0
aa2ar_human	337		C-term	R => C	missense	8.568e-06	1	116716	0	nan	0.912
aa2ar_human	337		C-term	R => H	missense	1.714e-05	2	116704	0	0.05	0.875
aa2ar_human	340		C-term	G => S	missense	8.634e-05	10	115820	0	nan	0.019
aa2ar_human	341		C-term	H => Y	missense	8.641e-06	1	115724	0	nan	0.0
aa2ar_human	342		C-term	P => L	missense	0.000156	18	115418	0	nan	0.058
aa2ar_human	344		C-term	G => R	missense	8.67e-06	1	115336	0	nan	0.303
aa2ar_human	345		C-term	V => L	missense	1.736e-05	2	115206	0	nan	0.001
aa2ar_human	349		C-term	G => S	missense	1.752e-05	2	114148	0	nan	0.657
aa2ar_human	354		C-term	P => R	missense	8.864e-06	1	112818	0	nan	0.1	LB (hydrophobic)
aa2ar_human	355		C-term	E => K	missense	8.872e-06	1	112718	0	nan	0.004	LB (aromatic (face-to-edge))
aa2ar_human	356		C-term	R => Q	missense	8.008e-05	9	112384	0	nan	0.003
aa2ar_human	358		C-term	P => S	missense	3.576e-05	4	111860	0	nan	0.298	LB (polar (hydrogen bond))
aa2ar_human	359		C-term	N => S	missense	1.787e-05	2	111920	0	nan	0.053
aa2ar_human	365		C-term	L => P	missense	9.428e-06	1	106062	0	nan	0.007
aa2ar_human	367		C-term	S => N	missense	3.81e-05	4	104988	0	nan	0.111
aa2ar_human	368		C-term	G => A	missense	9.546e-06	1	104760	0	nan	0.002
aa2ar_human	374		C-term	S => F	missense	9.714e-06	1	102944	0	nan	0.001	PTM (Phosphorylation)
aa2ar_human	375		C-term	Q => P	missense	9.744e-06	1	102628	0	nan	0.0	LB (hydrophobic)
aa2ar_human	378		C-term	T => M	missense	9.855e-06	1	101474	0	nan	0.001
aa2ar_human	383		C-term	V => M	missense	2.962e-05	3	101298	0	nan	0.362
aa2ar_human	384		C-term	E => D	missense	9.874e-06	1	101276	0	nan	0.129
aa2ar_human	388		C-term	H => Y	missense	1.967e-05	2	101658	0	nan	0.026
aa2ar_human	390		C-term	L => P	missense	9.809e-06	1	101942	0	nan	0.062
aa2ar_human	393		C-term	V => A	missense	9.768e-06	1	102378	0	nan	0.0
aa2ar_human	399		C-term	G => R	missense	1.944e-05	2	102876	0	nan	0.303
aa2ar_human	402		C-term	D => E	missense	0.002547	261	102478	5	nan	0.0
aa2ar_human	403		C-term	P => R	missense	1.952e-05	2	102468	0	nan	0.05
aa2ar_human	404		C-term	L => P	missense	1.958e-05	2	102146	0	nan	0.001

Residue

deleterious missense variants are shown in red
tolerated missense variants are shown in green
loss of function mutations ('stop gained' or 'frameshift' in the coding region) are shown in blue

Diagrams

SnakePlot Download: PNG | SVG
HelixBox Download: PNG | SVG

Versions

Package	Name	Version
Django		2.2.1
Python		3.6.7
debug_toolbar	Debug Toolbar	1.11
polymorphic	Polymorphic	2.0.3
rest_framework	Django REST framework	3.9.3
rest_framework_swagger	Rest_Framework_Swagger	2.2.0

Time

Resource usage

Resource	Value
User CPU time	152.978 msec
System CPU time	3.856 msec
Total CPU time	156.834 msec
Elapsed time	165.633 msec
Context switches	10 voluntary, 0 involuntary

Browser timing

Timing attribute	Timeline	Milliseconds since navigation start (+length)

Settings from `protwis.settings`

Setting	Value
ABSOLUTE_URL_OVERRIDES	`{}`
ADMINS	`[]`
ALLOWED_HOSTS	`['*']`
APPEND_SLASH	`True`
AUTHENTICATION_BACKENDS	`['django.contrib.auth.backends.ModelBackend']`
AUTH_PASSWORD_VALIDATORS	`'********************'`
AUTH_USER_MODEL	`'auth.User'`
BASE_DIR	`'/home/protwis/gpcrdb_test'`
BUILD_CACHE_DIR	`'/home/protwis/gpcrdb_data/cache'`
CACHES	`{'alignments': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test_alignment', 'OPTIONS': {'MAX_ENTRIES': 1000}}, 'default': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test/', 'OPTIONS': {'MAX_ENTRIES': 10000000}}}`
CACHE_MIDDLEWARE_ALIAS	`'default'`
CACHE_MIDDLEWARE_KEY_PREFIX	`'********************'`
CACHE_MIDDLEWARE_SECONDS	`600`
CSRF_COOKIE_AGE	`31449600`
CSRF_COOKIE_DOMAIN	`None`
CSRF_COOKIE_HTTPONLY	`False`
CSRF_COOKIE_NAME	`'csrftoken'`
CSRF_COOKIE_PATH	`'/'`
CSRF_COOKIE_SAMESITE	`'Lax'`
CSRF_COOKIE_SECURE	`False`
CSRF_FAILURE_VIEW	`'django.views.csrf.csrf_failure'`
CSRF_HEADER_NAME	`'HTTP_X_CSRFTOKEN'`
CSRF_TRUSTED_ORIGINS	`[]`
CSRF_USE_SESSIONS	`False`
DATABASES	`{'default': {'ATOMIC_REQUESTS': False, 'AUTOCOMMIT': True, 'CONN_MAX_AGE': 0, 'ENGINE': 'django.db.backends.postgresql_psycopg2', 'HOST': 'localhost', 'NAME': 'protwis_202107', 'OPTIONS': {}, 'PASSWORD': '********************', 'PORT': '', 'TEST': {'CHARSET': None, 'COLLATION': None, 'MIRROR': None, 'NAME': None}, 'TIME_ZONE': None, 'USER': 'protwis'}}`
DATABASE_ROUTERS	`[]`
DATA_DIR	`'/home/protwis/gpcrdb_data'`
DATA_UPLOAD_MAX_MEMORY_SIZE	`2621440`
DATA_UPLOAD_MAX_NUMBER_FIELDS	`1000`
DATETIME_FORMAT	`'N j, Y, P'`
DATETIME_INPUT_FORMATS	`['%Y-%m-%d %H:%M:%S', '%Y-%m-%d %H:%M:%S.%f', '%Y-%m-%d %H:%M', '%Y-%m-%d', '%m/%d/%Y %H:%M:%S', '%m/%d/%Y %H:%M:%S.%f', '%m/%d/%Y %H:%M', '%m/%d/%Y', '%m/%d/%y %H:%M:%S', '%m/%d/%y %H:%M:%S.%f', '%m/%d/%y %H:%M', '%m/%d/%y']`
DATE_FORMAT	`'N j, Y'`
DATE_INPUT_FORMATS	`['%Y-%m-%d', '%m/%d/%Y', '%m/%d/%y', '%b %d %Y', '%b %d, %Y', '%d %b %Y', '%d %b, %Y', '%B %d %Y', '%B %d, %Y', '%d %B %Y', '%d %B, %Y']`
DEBUG	`True`
DEBUG_PROPAGATE_EXCEPTIONS	`False`
DEBUG_TOOLBAR_PATCH_SETTINGS	`False`
DECIMAL_SEPARATOR	`'.'`
DEFAULT_CHARSET	`'utf-8'`
DEFAULT_CONTENT_TYPE	`'text/html'`
DEFAULT_EXCEPTION_REPORTER_FILTER	`'django.views.debug.SafeExceptionReporterFilter'`
DEFAULT_FILE_STORAGE	`'django.core.files.storage.FileSystemStorage'`
DEFAULT_FROM_EMAIL	`'webmaster@localhost'`
DEFAULT_INDEX_TABLESPACE	`''`
DEFAULT_NUMBERING_SCHEME	`'gpcrdb'`
DEFAULT_PROTEIN_STATE	`'inactive'`
DEFAULT_SITE	`'gpcr'`
DEFAULT_TABLESPACE	`''`
DISALLOWED_USER_AGENTS	`[]`
DOCUMENTATION_URL	`'https://docs.gpcrdb.org/'`
EMAIL_BACKEND	`'django.core.mail.backends.smtp.EmailBackend'`
EMAIL_HOST	`'localhost'`
EMAIL_HOST_PASSWORD	`'********************'`
EMAIL_HOST_USER	`''`
EMAIL_PORT	`25`
EMAIL_SSL_CERTFILE	`None`
EMAIL_SSL_KEYFILE	`'********************'`
EMAIL_SUBJECT_PREFIX	`'[Django] '`
EMAIL_TIMEOUT	`None`
EMAIL_USE_LOCALTIME	`False`
EMAIL_USE_SSL	`False`
EMAIL_USE_TLS	`False`
FILE_CHARSET	`'utf-8'`
FILE_UPLOAD_DIRECTORY_PERMISSIONS	`None`
FILE_UPLOAD_HANDLERS	`['django.core.files.uploadhandler.MemoryFileUploadHandler', 'django.core.files.uploadhandler.TemporaryFileUploadHandler']`
FILE_UPLOAD_MAX_MEMORY_SIZE	`2621440`
FILE_UPLOAD_PERMISSIONS	`None`
FILE_UPLOAD_TEMP_DIR	`None`
FIRST_DAY_OF_WEEK	`0`
FIXTURE_DIRS	`[]`
FORCE_SCRIPT_NAME	`None`
FORMAT_MODULE_PATH	`None`
FORM_RENDERER	`'django.forms.renderers.DjangoTemplates'`
GOOGLE_ANALYTICS_API	`'********************'`
GOOGLE_ANALYTICS_KEY	`'********************'`
IGNORABLE_404_URLS	`[]`
INSTALLED_APPS	('django.contrib.admin', 'django.contrib.auth', 'django.contrib.contenttypes', 'django.contrib.sessions', 'django.contrib.messages', 'django.contrib.staticfiles', 'django.contrib.humanize', 'debug_toolbar', 'rest_framework', 'rest_framework_swagger', 'polymorphic', 'common', 'api', 'news', 'pages', 'home', 'protein', 'family', 'residue', 'alignment', 'similaritysearch', 'similaritymatrix', 'structure', 'ligand', 'interaction', 'mutation', 'phylogenetic_trees', 'sitesearch', 'build_gpcr', 'construct', 'tools', 'drugs', 'signprot', 'signprot2', 'mutational_landscape', 'contactnetwork', 'seqsign', 'angles', 'hotspots')
INTERNAL_IPS	`'10.0.2.2'`
LANGUAGES	[('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')]
LANGUAGES_BIDI	`['he', 'ar', 'fa', 'ur']`
LANGUAGE_CODE	`'en-us'`
LANGUAGE_COOKIE_AGE	`None`
LANGUAGE_COOKIE_DOMAIN	`None`
LANGUAGE_COOKIE_NAME	`'django_language'`
LANGUAGE_COOKIE_PATH	`'/'`
LOCALE_PATHS	`[]`
LOGGING	{'disable_existing_loggers': False, 'formatters': {'verbose': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s] %(message)s'}, 'verbose_low': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s]'}}, 'handlers': {'build': {'class': 'logging.FileHandler', 'filename': 'logs/build.log', 'formatter': 'verbose', 'level': 'DEBUG'}, 'django': {'class': 'logging.FileHandler', 'filename': 'logs/django.log', 'formatter': 'verbose', 'level': 'WARNING'}, 'protwis': {'class': 'logging.FileHandler', 'filename': 'logs/protwis.log', 'formatter': 'verbose', 'level': 'DEBUG'}}, 'loggers': {'build': {'handlers': ['build'], 'level': 'DEBUG'}, 'django': {'handlers': ['django'], 'level': 'WARNING', 'propagate': True}, 'protwis': {'handlers': ['protwis'], 'level': 'DEBUG'}}, 'version': 1}
LOGGING_CONFIG	`'logging.config.dictConfig'`
LOGIN_REDIRECT_URL	`'/accounts/profile/'`
LOGIN_URL	`'/accounts/login/'`
LOGOUT_REDIRECT_URL	`None`
MANAGERS	`[]`
MEDIA_ROOT	`'/protwis/media/protwis'`
MEDIA_URL	`'/media/'`
MESSAGE_STORAGE	`'django.contrib.messages.storage.fallback.FallbackStorage'`
MIDDLEWARE	`('common.middleware.stats.StatsMiddleware', 'debug_toolbar.middleware.DebugToolbarMiddleware', 'django.contrib.sessions.middleware.SessionMiddleware', 'django.middleware.common.CommonMiddleware', 'django.middleware.csrf.CsrfViewMiddleware', 'django.contrib.auth.middleware.AuthenticationMiddleware', 'django.contrib.messages.middleware.MessageMiddleware', 'django.middleware.clickjacking.XFrameOptionsMiddleware')`
MIGRATION_MODULES	`{}`
MONTH_DAY_FORMAT	`'F j'`
NUMBER_GROUPING	`0`
PASSWORD_HASHERS	`'********************'`
PASSWORD_RESET_TIMEOUT_DAYS	`'********************'`
PREPEND_WWW	`False`
REFERENCE_POSITIONS	`{'D1S1': 'D1S1x50', 'D1S2': 'D1S2x50', 'D1T1': 'D1T1x50', 'D1e1': 'D1e1x50', 'ECL1': '23x50', 'ECL2': '45x50', 'H8': '8x50', 'ICL1': '12x50', 'ICL2': '34x50', 'TM1': '1x50', 'TM2': '2x50', 'TM3': '3x50', 'TM4': '4x50', 'TM5': '5x50', 'TM6': '6x50', 'TM7': '7x50'}`
ROOT_URLCONF	`'protwis.urls'`
SECRET_KEY	`'********************'`
SECURE_BROWSER_XSS_FILTER	`False`
SECURE_CONTENT_TYPE_NOSNIFF	`False`
SECURE_HSTS_INCLUDE_SUBDOMAINS	`False`
SECURE_HSTS_PRELOAD	`False`
SECURE_HSTS_SECONDS	`0`
SECURE_PROXY_SSL_HEADER	`None`
SECURE_REDIRECT_EXEMPT	`[]`
SECURE_SSL_HOST	`None`
SECURE_SSL_REDIRECT	`False`
SERVER_EMAIL	`'root@localhost'`
SESSION_CACHE_ALIAS	`'default'`
SESSION_COOKIE_AGE	`86400`
SESSION_COOKIE_DOMAIN	`None`
SESSION_COOKIE_HTTPONLY	`True`
SESSION_COOKIE_NAME	`'sessionid'`
SESSION_COOKIE_PATH	`'/'`
SESSION_COOKIE_SAMESITE	`'Lax'`
SESSION_COOKIE_SECURE	`False`
SESSION_ENGINE	`'django.contrib.sessions.backends.db'`
SESSION_EXPIRE_AT_BROWSER_CLOSE	`False`
SESSION_FILE_PATH	`None`
SESSION_SAVE_EVERY_REQUEST	`False`
SESSION_SERIALIZER	`'django.contrib.sessions.serializers.PickleSerializer'`
SETTINGS_MODULE	`'protwis.settings'`
SHORT_DATETIME_FORMAT	`'m/d/Y P'`
SHORT_DATE_FORMAT	`'m/d/Y'`
SIGNING_BACKEND	`'django.core.signing.TimestampSigner'`
SILENCED_SYSTEM_CHECKS	`[]`
SITE_NAME	`'gpcr'`
SITE_TITLE	`'GPCRdb'`
STATICFILES_DIRS	`('/home/protwis/gpcrdb_test/static',)`
STATICFILES_FINDERS	`['django.contrib.staticfiles.finders.FileSystemFinder', 'django.contrib.staticfiles.finders.AppDirectoriesFinder']`
STATICFILES_STORAGE	`'django.contrib.staticfiles.storage.StaticFilesStorage'`
STATIC_ROOT	`'/home/protwis/static_test/'`
STATIC_URL	`'/static/'`
SWAGGER_SETTINGS	`{'USE_SESSION_AUTH': False}`
TEMPLATES	[{'APP_DIRS': True, 'BACKEND': 'django.template.backends.django.DjangoTemplates', 'DIRS': [], 'OPTIONS': {'context_processors': ['django.contrib.auth.context_processors.auth', 'django.template.context_processors.debug', 'django.template.context_processors.i18n', 'django.template.context_processors.media', 'django.template.context_processors.static', 'django.template.context_processors.tz', 'django.contrib.messages.context_processors.messages', 'protwis.context_processors.current_site', 'protwis.context_processors.canonical_tag', 'protwis.context_processors.documentation_url', 'protwis.context_processors.google_analytics', 'protwis.context_processors.site_title'], 'debug': True}}]
TEST_NON_SERIALIZED_APPS	`[]`
TEST_RUNNER	`'django.test.runner.DiscoverRunner'`
THOUSAND_SEPARATOR	`','`
TIME_FORMAT	`'P'`
TIME_INPUT_FORMATS	`['%H:%M:%S', '%H:%M:%S.%f', '%H:%M']`
TIME_ZONE	`'Europe/Copenhagen'`
USE_I18N	`True`
USE_L10N	`True`
USE_THOUSAND_SEPARATOR	`False`
USE_TZ	`True`
USE_X_FORWARDED_HOST	`False`
USE_X_FORWARDED_PORT	`False`
WSGI_APPLICATION	`None`
X_FRAME_OPTIONS	`'SAMEORIGIN'`
YEAR_MONTH_FORMAT	`'F Y'`

Headers

Request headers

Key	Value
Accept	text/html,application/xhtml+xml,application/xml;q=0.9,/;q=0.8
Accept-Encoding	br,gzip
Accept-Language	en-US,en;q=0.5
Connection	close
Host	test.gpcrdb.org
User-Agent	CCBot/2.0 (https://commoncrawl.org/faq/)
X-Forwarded-For	3.236.207.90
X-Forwarded-Proto	https
X-Real-Ip	3.236.207.90

Response headers

Key	Value
Content-Length	524444
Content-Type	text/html; charset=utf-8
Vary	Cookie
X-Frame-Options	SAMEORIGIN

WSGI environ

Since the WSGI environ inherits the environment of the server, only a significant subset is shown below.

Key	Value
PATH_INFO	/mutational_landscape/protein/AA2AR_human/
QUERY_STRING
REMOTE_ADDR
REQUEST_METHOD	GET
SCRIPT_NAME
SERVER_NAME	test.gpcrdb.org
SERVER_PORT	443
SERVER_PROTOCOL	HTTP/1.0
SERVER_SOFTWARE	gunicorn/19.9.0

Request

View information

View function	Arguments	Keyword arguments	URL name
`mutational_landscape.views.render_variants`	`()`	`{'protein': 'AA2AR_human'}`	`render`

No cookies

No session data

No GET data

No POST data

SQL queries from 1 connection

default 2.62 ms (1 query )

	Query	Timeline	Time (ms)	Action
	+	SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 'aa2ar_human'	100.0%	2.62
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89) proteins.append(Protein.objects.get(entry_name=protein.lower()))

Query

Timeline

Time (ms)

Action

SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 'aa2ar_human'

100.0%

2.62

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89)
  proteins.append(Protein.objects.get(entry_name=protein.lower()))

Static files (590 found, 40 used)

Static file path

/home/protwis/gpcrdb_test/static

Static file apps

django.contrib.admin
debug_toolbar
rest_framework
rest_framework_swagger
polymorphic

Static files

bootstrap/css/bootstrap.min.css: /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-submenu.min.css: /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
home/css/jquery-ui.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery-ui.min.css
home/css/jquery-ui.theme.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery-ui.theme.min.css
home/css/bootstrap-treeview.min.css: /home/protwis/gpcrdb_test/static/home/css/bootstrap-treeview.min.css
home/css/style.css: /home/protwis/gpcrdb_test/static/home/css/style.css
flowplayer/flowplayer.css: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
home/css/cookieconsent.min.css: /home/protwis/gpcrdb_test/static/home/css/cookieconsent.min.css
home/css/jquery.dataTables.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery.dataTables.min.css
home/css/structure_browser.css: /home/protwis/gpcrdb_test/static/home/css/structure_browser.css
home/css/residue_table.css: /home/protwis/gpcrdb_test/static/home/css/residue_table.css
home/css/alignment.css: /home/protwis/gpcrdb_test/static/home/css/alignment.css
: /home/protwis/gpcrdb_test/static
home/css/mainmenu.css: /home/protwis/gpcrdb_test/static/home/css/mainmenu.css
home/css/modal.css: /home/protwis/gpcrdb_test/static/home/css/modal.css
home/css/jquery.powertip.css: /home/protwis/gpcrdb_test/static/home/css/jquery.powertip.css
home/js/jquery-3.1.1.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/citation_tool.js: /home/protwis/gpcrdb_test/static/home/js/citation_tool.js
home/js/joinus_tool.js: /home/protwis/gpcrdb_test/static/home/js/joinus_tool.js
home/js/jquery-3.1.1.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/jquery-ui.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-ui.min.js
bootstrap/js/bootstrap.min.js: /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/js/bootstrap-submenu.js: /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
home/js/navbar-autocomplete.js: /home/protwis/gpcrdb_test/static/home/js/navbar-autocomplete.js
home/js/svg-pan-zoom.min.js: /home/protwis/gpcrdb_test/static/home/js/svg-pan-zoom.min.js
home/js/bootstrap-treeview.min.js: /home/protwis/gpcrdb_test/static/home/js/bootstrap-treeview.min.js
home/js/papaparse.min.js: /home/protwis/gpcrdb_test/static/home/js/papaparse.min.js
flowplayer/flowplayer.min.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.min.js
flowplayer/flowplayer.overlay.min.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.min.js
flowplayer/flowplayer.overlay.bootstrap.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.bootstrap.js
home/js/gpcrdb.js: /home/protwis/gpcrdb_test/static/home/js/gpcrdb.js
home/js/cookieconsent.min.js: /home/protwis/gpcrdb_test/static/home/js/cookieconsent.min.js
home/js/jquery.dataTables.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.min.js
home/js/dataTables.tableTools.min.js: /home/protwis/gpcrdb_test/static/home/js/dataTables.tableTools.min.js
home/js/jquery.dataTables.columnFilter.js: /home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.columnFilter.js
home/js/selection.js: /home/protwis/gpcrdb_test/static/home/js/selection.js
home/js/saveSvgAsPng.js: /home/protwis/gpcrdb_test/static/home/js/saveSvgAsPng.js
home/js/alignment.js: /home/protwis/gpcrdb_test/static/home/js/alignment.js
home/js/diagrams.js: /home/protwis/gpcrdb_test/static/home/js/diagrams.js
home/js/residuetable.js: /home/protwis/gpcrdb_test/static/home/js/residuetable.js

django.contrib.staticfiles.finders.FileSystemFinder (415 files)

Path	Location
visualization_scripts/maestro_label_generic_numbers.py	/home/protwis/gpcrdb_test/static/visualization_scripts/maestro_label_generic_numbers.py
visualization_scripts/pymol_view_generic_numbers.pml	/home/protwis/gpcrdb_test/static/visualization_scripts/pymol_view_generic_numbers.pml
bootstrap/js/npm.js	/home/protwis/gpcrdb_test/static/bootstrap/js/npm.js
bootstrap/js/bootstrap.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.js
bootstrap/js/bootstrap-submenu.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
bootstrap/js/bootstrap.min.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/fonts/glyphicons-halflings-regular.eot	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.eot
bootstrap/fonts/glyphicons-halflings-regular.woff	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff
bootstrap/fonts/glyphicons-halflings-regular.ttf	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.ttf
bootstrap/fonts/glyphicons-halflings-regular.svg	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.svg
bootstrap/fonts/glyphicons-halflings-regular.woff2	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff2
bootstrap/css/bootstrap.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css.map
bootstrap/css/bootstrap-submenu.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css
bootstrap/css/bootstrap.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css
bootstrap/css/bootstrap-theme.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css.map
bootstrap/css/bootstrap-theme.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css.map
bootstrap/css/bootstrap-submenu.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
bootstrap/css/bootstrap.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css.map
bootstrap/css/bootstrap-submenu.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css.map
bootstrap/css/bootstrap.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-theme.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css
bootstrap/css/bootstrap-theme.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css
blast/protwis_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psq
blast/protwis_human_bundle_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pin
blast/protwis_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pin
blast/protwis_human_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.phr
blast/protwis_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psd
blast/protwis_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.phr
blast/protwis_human_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psq
blast/protwis_human_gpcr_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.phr
blast/protwis_human_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psq
blast/protwis_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psd
blast/protwis_human_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pin
blast/protwis_human_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psd
blast/protwis_human_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pog
blast/.gitignore	/home/protwis/gpcrdb_test/static/blast/.gitignore
blast/protwis_human_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psd
blast/protwis_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pog
blast/protwis_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psq
blast/protwis_human_gpcr_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psi
blast/protwis_gpcr_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.pin
blast/protwis_human_bundle_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pog
blast/protwis_human_gpcr_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.pog
blast/protwis_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psi
blast/protwis_human_bundle_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.psd
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django.contrib.staticfiles.finders.AppDirectoriesFinder (175 files)

Templates (9 rendered)

Template paths

None

Templates

browser.html: /home/protwis/gpcrdb_test/mutational_landscape/templates/browser.html; Toggle context
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'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')], 'LANGUAGE_BIDI': False, 'LANGUAGE_CODE': 'en-us', 'MEDIA_URL': '/media/', 'STATIC_URL': '/static/', 'TIME_ZONE': 'Europe/Copenhagen', 'canonical_tag': 'https://gpcrdb.org/mutational_landscape/protein/AA2AR_human/', 'csrf_token': <SimpleLazyObject: 'OrM5PbDMM3BkQsv3qnZfPgDetXh8L3h1NHBzsNloZF5fnswfiFx0u8mq3ge2X8wn'>, 'current_site': 'gpcr', 'debug': True, 'documentation_url': 'https://docs.gpcrdb.org/', 'messages': <django.contrib.messages.storage.fallback.FallbackStorage object at 0x7f2e6bd7c0f0>, 'perms': <django.contrib.auth.context_processors.PermWrapper object at 0x7f2e7373e9e8>, 'site_title': 'GPCRdb', 'sql_queries': <function debug.<locals>.<lambda> at 0x7f2e734b1048>, 'user': <SimpleLazyObject: <django.contrib.auth.models.AnonymousUser object at 0x7f2e7373e9b0>>} {'HelixBox': <common.diagrams_gpcr.DrawHelixBox object at 0x7f2e2ec2a860>, 'SnakePlot': <common.diagrams_gpcr.DrawSnakePlot object at 0x7f2e8020b710>, 'mutations': '<<queryset of mutational_landscape.NaturalMutations>>', 'mutations_pos_list': '{"28": ["S", 8.271e-06, 1, 120902, 0, "missense", ' '"deleterious", "#e30e0e", ""], "138": ["SerfsTer31", ' '8.433e-06, 1, 118582, 0, "frameshift", "deleterious", ' '"#575c9d", ""], "179": ["H", 8.237e-06, 1, 121404, 0, ' '"missense", "deleterious", "#e30e0e", ""], "197": ' '["LeufsTer134", 8.237e-06, 1, 121398, 0, "frameshift", ' '"deleterious", "#575c9d", "SodiumPocket MicroSwitch ' '"], "206": ["Q", 4.119e-05, 5, 121380, 0, "missense", ' '"tolerated", "#70c070", "GP (contact) "], "382": ' '["ArgfsTer6", 1.971e-05, 2, 101496, 0, "frameshift", ' '"deleterious", "#575c9d", ""], "412": ["LeufsTer36", ' '1.984e-05, 2, 100828, 0, "frameshift", "deleterious", ' '"#575c9d", ""], "4": ["T", 0.0001264, 10, 79096, 0, ' '"missense", "tolerated", "#70c070", ""], "6": ["F", ' '1.138e-05, 1, 87846, 0, "missense", "tolerated", ' '"#70c070", ""], "7": ["L", 1.084e-05, 1, 92226, 0, ' '"missense", "tolerated", "#70c070", ""], "8": ["A", ' '1.998e-05, 2, 100104, 0, "missense", "tolerated", ' '"#70c070", ""], "15": ["T", 8.653e-05, 10, 115572, 0, ' '"missense", "tolerated", "#70c070", ""], "21": ["V", ' '3.34e-05, 4, 119762, 0, "missense", "tolerated", ' '"#70c070", ""], "23": ["D", 8.312e-06, 1, 120308, 0, ' '"missense", "deleterious", "#e30e0e", ""], "24": ["S", ' '8.296e-06, 1, 120538, 0, "missense", "deleterious", ' '"#e30e0e", ""], "33": ["R", 8.255e-06, 1, 121132, 0, ' '"missense", "deleterious", "#e30e0e", ""], "40": ["I", ' '0.0001897, 23, 121232, 0, "missense", "tolerated", ' '"#70c070", ""], "49": ["V", 4.129e-05, 5, 121102, 0, ' '"missense", "deleterious", "#e30e0e", ""], "50": ["V", ' '0.00253, 306, 120926, 7, "missense", "tolerated", ' '"#70c070", ""], "52": ["N", 8.255e-06, 1, 121142, 0, ' '"missense", "deleterious", "#e30e0e", ""], "54": ["T", ' '8.254e-06, 1, 121152, 0, "missense", "deleterious", ' '"#e30e0e", ""], "59": ["T", 8.252e-06, 1, 121190, 0, ' '"missense", "deleterious", "#e30e0e", ""], "60": ["V", ' '8.25e-06, 1, 121210, 0, "missense", "tolerated", ' '"#70c070", ""], "66": ["V", 8.247e-06, 1, 121258, 0, ' '"missense", "deleterious", "#e30e0e", "LB ' '(hydrophobic) "], "67": ["R", 8.246e-06, 1, 121268, 0, ' '"missense", "deleterious", "#e30e0e", "LB (polar ' '(hydrogen bond)) "], "68": ["I", 8.246e-06, 1, 121270, ' '0, "missense", "tolerated", "#70c070", ""], "69": ' '["R", 1.649e-05, 2, 121274, 0, "missense", ' '"deleterious", "#e30e0e", ""], "72": ["V", 8.245e-06, ' '1, 121284, 0, "missense", "tolerated", "#70c070", ""], ' '"88": ["R", 1.649e-05, 2, 121322, 0, "missense", ' '"deleterious", "#e30e0e", "LB (polar (hydrogen bond)) ' '"], "89": ["H", 8.242e-06, 1, 121326, 0, "missense", ' '"deleterious", "#e30e0e", ""], "102": ["H", 8.263e-06, ' '1, 121024, 0, "missense", "deleterious", "#e30e0e", ' '"SodiumPocket MicroSwitch GP (contact) "], "105": ' '["T", 8.287e-06, 1, 120670, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "107": ' '["C", 1.665e-05, 2, 120156, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "111": ' '["W", 8.457e-06, 1, 118246, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "116": ' '["M", 9.016e-06, 1, 110914, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "121": ' '["S", 8.964e-06, 1, 111552, 0, "missense", ' '"deleterious", "#e30e0e", ""], "123": ["D", 8.929e-06, ' '1, 111996, 0, "missense", "deleterious", "#e30e0e", ' '""], "125": ["T", 8.884e-06, 1, 112566, 0, "missense", ' '"deleterious", "#e30e0e", ""], "130": ["M", 3.51e-05, ' '4, 113958, 0, "missense", "deleterious", "#e30e0e", ' '""], "136": ["S", 1.702e-05, 2, 117524, 0, "missense", ' '"deleterious", "#e30e0e", ""], "140": ["I", 8.354e-06, ' '1, 119696, 0, "missense", "deleterious", "#e30e0e", ' '""], "141": ["Q", 4.171e-05, 5, 119886, 0, "missense", ' '"deleterious", "#e30e0e", ""], "147": ["C", 2.485e-05, ' '3, 120706, 0, "missense", "deleterious", "#e30e0e", ' '""], "148": ["R", 4.138e-05, 5, 120844, 0, "missense", ' '"tolerated", "#70c070", ""], "156": ["T", 8.251e-06, ' '1, 121200, 0, "missense", "tolerated", "#70c070", ""], ' '"158": ["S", 8.247e-06, 1, 121262, 0, "missense", ' '"tolerated", "#70c070", ""], "160": ["R", 0.0001814, ' '22, 121292, 0, "missense", "tolerated", "#70c070", ' '""], "161": ["K", 8.243e-06, 1, 121320, 0, "missense", ' '"tolerated", "#70c070", ""], "165": ["S", 2.472e-05, ' '3, 121360, 0, "missense", "tolerated", "#70c070", ""], ' '"174": ["V", 8.238e-06, 1, 121388, 0, "missense", ' '"deleterious", "#e30e0e", "LB (hydrophobic) "], "184": ' '["T", 8.237e-05, 10, 121402, 0, "missense", ' '"deleterious", "#e30e0e", ""], "186": ["M", 8.237e-06, ' '1, 121402, 0, "missense", "deleterious", "#e30e0e", ' '"SodiumPocket MicroSwitch LB (hydrophobic) "], "192": ' '["P", 8.237e-06, 1, 121398, 0, "missense", ' '"deleterious", "#e30e0e", ""], "199": ["Q", 2.471e-05, ' '3, 121394, 0, "missense", "deleterious", "#e30e0e", ' '""], "203": ["V", 1.648e-05, 2, 121382, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "205": ' '["Q", 1.648e-05, 2, 121380, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "212": ' '["K", 8.238e-06, 1, 121382, 0, "missense", ' '"tolerated", "#70c070", ""], "215": ["L", 8.239e-06, ' '1, 121380, 0, "missense", "tolerated", "#70c070", ""], ' '"217": ["R", 8.239e-06, 1, 121370, 0, "missense", ' '"tolerated", "#70c070", ""], "220": ["Q", 8.239e-06, ' '1, 121378, 0, "missense", "tolerated", "#70c070", ""], ' '"222": ["Q", 8.239e-06, 1, 121380, 0, "missense", ' '"deleterious", "#e30e0e", ""], "228": ["D", 1.648e-05, ' '2, 121384, 0, "missense", "deleterious", "#e30e0e", ' '"SodiumPocket MicroSwitch "], "229": ["I", 8.238e-06, ' '1, 121384, 0, "missense", "tolerated", "#70c070", ""], ' '"242": ["S", 8.238e-06, 1, 121386, 0, "missense", ' '"deleterious", "#e30e0e", "SodiumPocket MicroSwitch ' '"], "249": ["P", 8.238e-06, 1, 121392, 0, "missense", ' '"deleterious", "#e30e0e", "LB (hydrophobic) "], "261": ' '["N", 1.648e-05, 2, 121384, 0, "missense", ' '"tolerated", "#70c070", ""], "262": ["G", 8.238e-06, ' '1, 121390, 0, "missense", "deleterious", "#e30e0e", ' '""], "265": ["T", 8.238e-06, 1, 121384, 0, "missense", ' '"tolerated", "#70c070", ""], "270": ["T", 1.648e-05, ' '2, 121386, 0, "missense", "deleterious", "#e30e0e", ' '"LB (hydrophobic) "], "273": ["G", 8.239e-06, 1, ' '121378, 0, "missense", "tolerated", "#70c070", ""], ' '"275": ["I", 0.0001895, 23, 121372, 0, "missense", ' '"tolerated", "#70c070", ""], "280": ["S", 8.24e-06, 1, ' '121362, 0, "missense", "deleterious", "#e30e0e", ""], ' '"281": ["L", 8.24e-06, 1, 121356, 0, "missense", ' '"deleterious", "#e30e0e", ""], "290": ["F", 2.473e-05, ' '3, 121312, 0, "missense", "tolerated", "#70c070", "GP ' '(contact) "], "291": ["H", 8.243e-06, 1, 121316, 0, ' '"missense", "deleterious", "#e30e0e", "GP (contact) ' '"], "293": ["C", 7.419e-05, 9, 121312, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "294": ' '["D", 8.244e-06, 1, 121304, 0, "missense", ' '"tolerated", "#70c070", "GP (contact) "], "295": ["L", ' '8.244e-06, 1, 121302, 0, "missense", "deleterious", ' '"#e30e0e", ""], "296": ["H", 2.473e-05, 3, 121300, 0, ' '"missense", "deleterious", "#e30e0e", "GP (contact) ' '"], "300": ["L", 8.245e-06, 1, 121280, 0, "missense", ' '"tolerated", "#70c070", ""], "304": ["H", 7.425e-05, ' '9, 121210, 0, "missense", "tolerated", "#70c070", ""], ' '"306": ["Q", 8.255e-06, 1, 121136, 0, "missense", ' '"deleterious", "#e30e0e", ""], "307": ["I", 1.651e-05, ' '2, 121134, 0, "missense", "tolerated", "#70c070", ""], ' '"308": ["P", 3.303e-05, 4, 121108, 0, "missense", ' '"deleterious", "#e30e0e", ""], "309": ["K", 8.258e-06, ' '1, 121090, 0, "missense", "tolerated", "#70c070", ""], ' '"320": ["N", 8.319e-06, 1, 120212, 0, "missense", ' '"tolerated", "#70c070", ""], "329": ["N", 8.433e-06, ' '1, 118588, 0, "missense", "tolerated", "#70c070", ""], ' '"330": ["G", 8.444e-06, 1, 118430, 0, "missense", ' '"tolerated", "#70c070", ""], "331": ["R", 3.383e-05, ' '4, 118224, 0, "missense", "tolerated", "#70c070", ""], ' '"334": ["I", 1.703e-05, 2, 117410, 0, "missense", ' '"tolerated", "#70c070", ""], "337": ["H", 1.714e-05, ' '2, 116704, 0, "missense", "deleterious", "#e30e0e", ' '""], "340": ["S", 8.634e-05, 10, 115820, 0, ' '"missense", "tolerated", "#70c070", ""], "341": ["Y", ' '8.641e-06, 1, 115724, 0, "missense", "tolerated", ' '"#70c070", ""], "342": ["L", 0.000156, 18, 115418, 0, ' '"missense", "tolerated", "#70c070", ""], "344": ["R", ' '8.67e-06, 1, 115336, 0, "missense", "deleterious", ' '"#e30e0e", ""], "345": ["L", 1.736e-05, 2, 115206, 0, ' '"missense", "tolerated", "#70c070", ""], "349": ["S", ' '1.752e-05, 2, 114148, 0, "missense", "deleterious", ' '"#e30e0e", ""], "354": ["R", 8.864e-06, 1, 112818, 0, ' '"missense", "deleterious", "#e30e0e", "LB ' '(hydrophobic) "], "355": ["K", 8.872e-06, 1, 112718, ' '0, "missense", "tolerated", "#70c070", "LB (aromatic ' '(face-to-edge)) "], "356": ["Q", 8.008e-05, 9, 112384, ' '0, "missense", "tolerated", "#70c070", ""], "358": ' '["S", 3.576e-05, 4, 111860, 0, "missense", ' '"deleterious", "#e30e0e", "LB (polar (hydrogen bond)) ' '"], "359": ["S", 1.787e-05, 2, 111920, 0, "missense", ' '"tolerated", "#70c070", ""], "365": ["P", 9.428e-06, ' '1, 106062, 0, "missense", "tolerated", "#70c070", ""], ' '"367": ["N", 3.81e-05, 4, 104988, 0, "missense", ' '"deleterious", "#e30e0e", ""], "368": ["A", 9.546e-06, ' '1, 104760, 0, "missense", "tolerated", "#70c070", ""], ' '"374": ["F", 9.714e-06, 1, 102944, 0, "missense", ' '"tolerated", "#70c070", "PTM (Phosphorylation) "], ' '"375": ["P", 9.744e-06, 1, 102628, 0, "missense", ' '"tolerated", "#70c070", "LB (hydrophobic) "], "378": ' '["M", 9.855e-06, 1, 101474, 0, "missense", ' '"tolerated", "#70c070", ""], "383": ["M", 2.962e-05, ' '3, 101298, 0, "missense", "deleterious", "#e30e0e", ' '""], "384": ["D", 9.874e-06, 1, 101276, 0, "missense", ' '"deleterious", "#e30e0e", ""], "388": ["Y", 1.967e-05, ' '2, 101658, 0, "missense", "tolerated", "#70c070", ""], ' '"390": ["P", 9.809e-06, 1, 101942, 0, "missense", ' '"tolerated", "#70c070", ""], "393": ["A", 9.768e-06, ' '1, 102378, 0, "missense", "tolerated", "#70c070", ""], ' '"399": ["R", 1.944e-05, 2, 102876, 0, "missense", ' '"deleterious", "#e30e0e", ""], "402": ["E", 0.002547, ' '261, 102478, 5, "missense", "tolerated", "#70c070", ' '""], "403": ["R", 1.952e-05, 2, 102468, 0, "missense", ' '"tolerated", "#70c070", ""], "404": ["P", 1.958e-05, ' '2, 102146, 0, "missense", "tolerated", "#70c070", ""]}', 'natural_mutations_pos_list': '{"4": {"val": 1, "AA": "T "}, "6": {"val": 1, ' '"AA": "F "}, "7": {"val": 1, "AA": "L "}, "8": ' '{"val": 1, "AA": "A "}, "15": {"val": 1, "AA": ' '"T "}, "21": {"val": 1, "AA": "V "}, "23": ' '{"val": 1, "AA": "D "}, "24": {"val": 1, "AA": ' '"S "}, "28": {"val": 2, "AA": "ValfsTer74 S ' '"}, "33": {"val": 1, "AA": "R "}, "40": ' '{"val": 1, "AA": "I "}, "49": {"val": 1, "AA": ' '"V "}, "50": {"val": 1, "AA": "V "}, "52": ' '{"val": 1, "AA": "N "}, "54": {"val": 1, "AA": ' '"T "}, "59": {"val": 1, "AA": "T "}, "60": ' '{"val": 1, "AA": "V "}, "66": {"val": 1, "AA": ' '"V "}, "67": {"val": 1, "AA": "R "}, "68": ' '{"val": 1, "AA": "I "}, "69": {"val": 1, "AA": ' '"R "}, "72": {"val": 2, "AA": "T V "}, "88": ' '{"val": 1, "AA": "R "}, "89": {"val": 1, "AA": ' '"H "}, "102": {"val": 1, "AA": "H "}, "105": ' '{"val": 1, "AA": "T "}, "107": {"val": 1, ' '"AA": "C "}, "111": {"val": 1, "AA": "W "}, ' '"116": {"val": 1, "AA": "M "}, "121": {"val": ' '1, "AA": "S "}, "123": {"val": 1, "AA": "D "}, ' '"125": {"val": 1, "AA": "T "}, "130": {"val": ' '1, "AA": "M "}, "136": {"val": 1, "AA": "S "}, ' '"138": {"val": 1, "AA": "SerfsTer31 "}, "140": ' '{"val": 1, "AA": "I "}, "141": {"val": 1, ' '"AA": "Q "}, "174": {"val": 1, "AA": "V "}, ' '"179": {"val": 2, "AA": "GlufsTer156 H "}, ' '"184": {"val": 1, "AA": "T "}, "186": {"val": ' '1, "AA": "M "}, "192": {"val": 1, "AA": "P "}, ' '"197": {"val": 1, "AA": "LeufsTer134 "}, ' '"199": {"val": 2, "AA": "W Q "}, "203": ' '{"val": 1, "AA": "V "}, "205": {"val": 1, ' '"AA": "Q "}, "206": {"val": 2, "AA": "Ter Q ' '"}, "212": {"val": 1, "AA": "K "}, "220": ' '{"val": 1, "AA": "Q "}, "222": {"val": 3, ' '"AA": "G W Q "}, "228": {"val": 1, "AA": "D ' '"}, "229": {"val": 1, "AA": "I "}, "242": ' '{"val": 1, "AA": "S "}, "249": {"val": 1, ' '"AA": "P "}, "270": {"val": 1, "AA": "T "}, ' '"273": {"val": 1, "AA": "G "}, "275": {"val": ' '1, "AA": "I "}, "280": {"val": 1, "AA": "S "}, ' '"281": {"val": 1, "AA": "L "}, "290": {"val": ' '1, "AA": "F "}, "291": {"val": 2, "AA": "C H ' '"}, "293": {"val": 1, "AA": "C "}, "294": ' '{"val": 1, "AA": "D "}, "295": {"val": 1, ' '"AA": "L "}, "296": {"val": 1, "AA": "H "}, ' '"300": {"val": 2, "AA": "H L "}, "304": ' '{"val": 2, "AA": "C H "}, "306": {"val": 2, ' '"AA": "R Q "}, "307": {"val": 1, "AA": "I "}, ' '"308": {"val": 1, "AA": "P "}, "309": {"val": ' '1, "AA": "K "}, "color": ["#c79494", ' '"#c54a4a", "#c40100"]}', 'receptor': 'aa2ar_human', 'type': 'protein'} {'hosts': {'arrestin': '', 'gpcr': '', 'gprotein': ''}}

Context processors

django.template.context_processors.csrf: Toggle context
{'csrf_token': <SimpleLazyObject: 'OrM5PbDMM3BkQsv3qnZfPgDetXh8L3h1NHBzsNloZF5fnswfiFx0u8mq3ge2X8wn'>}
django.contrib.auth.context_processors.auth: Toggle context
{'user': <SimpleLazyObject: <django.contrib.auth.models.AnonymousUser object at 0x7f2e7373e9b0>>, 'perms': <django.contrib.auth.context_processors.PermWrapper object at 0x7f2e7373e9e8>}
django.template.context_processors.debug: Toggle context
{'debug': True, 'sql_queries': <function debug.<locals>.<lambda> at 0x7f2e734b1048>}
django.template.context_processors.i18n: Toggle context
{'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')], 'LANGUAGE_CODE': 'en-us', 'LANGUAGE_BIDI': False}
django.template.context_processors.media: Toggle context
{'MEDIA_URL': '/media/'}
django.template.context_processors.static: Toggle context
{'STATIC_URL': '/static/'}
django.template.context_processors.tz: Toggle context
{'TIME_ZONE': 'Europe/Copenhagen'}
django.contrib.messages.context_processors.messages: Toggle context
{'messages': <django.contrib.messages.storage.fallback.FallbackStorage object at 0x7f2e6bd7c0f0>, 'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30, 'ERROR': 40}}
protwis.context_processors.current_site: Toggle context
{'current_site': 'gpcr'}
protwis.context_processors.canonical_tag: Toggle context
{'canonical_tag': 'https://gpcrdb.org/mutational_landscape/protein/AA2AR_human/'}
protwis.context_processors.documentation_url: Toggle context
{'documentation_url': 'https://docs.gpcrdb.org/'}
protwis.context_processors.google_analytics: Toggle context
{}
protwis.context_processors.site_title: Toggle context
{'site_title': 'GPCRdb'}

Cache calls from 2 backends

Summary

Total calls	Total time	Cache hits	Cache misses
3	24.25551414489746 ms	2	0

Commands

add	get	set	delete	clear	get_many	set_many	delete_many	has_key	incr	decr	incr_version	decr_version
0	2	0	0	0	0	0	0	1	0	0	0	0

Calls

Time (ms)		Type	Arguments	Keyword arguments	Backend
+	0.6373	has_key	('VARIATION_968aa043fca593aa798b9cda216b7fe1',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e8036f128>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(122) if not cache_variation.has_key(cache_key) and len(proteins)>0:
+	23.4847	get	('VARIATION_968aa043fca593aa798b9cda216b7fe1',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e8036f128>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(252) cache_data = cache_variation.get(cache_key)
+	0.1335	get	('citation_urls',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e8036f128>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(292) return render(request, 'browser.html', cache_data) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/shortcuts.py in render(36) content = loader.render_to_string(template_name, context, request, using=using) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/loader.py in render_to_string(62) return template.render(context, request) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/backends/django.py in render(61) return self.template.render(context) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/base.py in render(169) with context.bind_template(self): /usr/lib/python3.6/

Path	Location
admin/js/cancel.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/cancel.js
admin/js/autocomplete.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/autocomplete.js
admin/js/collapse.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.min.js
admin/js/actions.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.min.js
admin/js/urlify.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/urlify.js
admin/js/popup_response.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/popup_response.js
admin/js/collapse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.js
admin/js/SelectBox.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectBox.js
admin/js/calendar.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/calendar.js
admin/js/actions.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.js
admin/js/prepopulate.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate.min.js
admin/js/SelectFilter2.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectFilter2.js
admin/js/timeparse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/timeparse.js
admin/js/jquery.init.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/jquery.init.js
admin/js/core.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/core.js
admin/js/prepopulate_init.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate_init.js
admin/js/inlines.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/inlines.js
admin/js/inlines.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/inlines.min.js
admin/js/change_form.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/change_form.js
admin/js/prepopulate.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate.js
admin/js/vendor/xregexp/xregexp.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/xregexp/xregexp.js
admin/js/vendor/xregexp/LICENSE.txt	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/xregexp/LICENSE.txt
admin/js/vendor/xregexp/xregexp.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/xregexp/xregexp.min.js
admin/js/vendor/jquery/jquery.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/jquery/jquery.min.js
admin/js/vendor/jquery/LICENSE.txt	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/jquery/LICENSE.txt
admin/js/vendor/jquery/jquery.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/jquery/jquery.js
admin/js/vendor/select2/select2.full.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/select2.full.js
admin/js/vendor/select2/select2.full.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/select2.full.min.js
admin/js/vendor/select2/LICENSE.md	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/LICENSE.md
admin/js/vendor/select2/i18n/eu.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/eu.js
admin/js/vendor/select2/i18n/he.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/he.js
admin/js/vendor/select2/i18n/ca.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/ca.js
admin/js/vendor/select2/i18n/id.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/id.js
admin/js/vendor/select2/i18n/fi.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/fi.js
admin/js/vendor/select2/i18n/sr.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/sr.js
admin/js/vendor/select2/i18n/az.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/az.js
admin/js/vendor/select2/i18n/da.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/da.js
admin/js/vendor/select2/i18n/hu.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/hu.js
admin/js/vendor/select2/i18n/zh-CN.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/zh-CN.js
admin/js/vendor/select2/i18n/fa.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/fa.js

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