GPCRdb

Variation Browser

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Receptor	Position	GPCRdb	Segment	Variant	Mutation type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation


Receptor	Position	GPCRdb	Segment	Variant	Mutation Type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation
cltr1_human	220		ICL3	S => IlefsTer10	frameshift	1.221e-05	1	81928	0	None	None
cltr1_human	180	5.29x30	TM5	N => LysfsTer25	frameshift	1.218e-05	1	82122	0	None	None
cltr1_human	130	34.52x52	ICL2	Q => Ter	stop gained	2.339e-05	2	85512	0	None	None	GP (contact)
cltr1_human	122	3.51x51	TM3	C => Ter	stop gained	1.168e-05	1	85641	0	None	None
cltr1_human	65	2.46x46	TM2	L => Ter	stop gained	1.15e-05	1	86924	0	None	None
cltr1_human	18	1.27x27	TM1	I => Ter	frameshift	1.163e-05	1	86002	0	None	None
cltr1_human	336		C-term	K => R	missense	1.249e-05	1	80039	0	nan	0.001
cltr1_human	335		C-term	C => R	missense	1.243e-05	1	80449	0	nan	0.009
cltr1_human	331		C-term	G => R	missense	1.222e-05	1	81839	0	0.29	0.043
cltr1_human	330		C-term	K => R	missense	0.0003042	25	82175	0	0.23	0.002
cltr1_human	325		C-term	A => T	missense	0.000488	41	84014	0	0.46	0.0
cltr1_human	325		C-term	A => S	missense	1.19e-05	1	84014	0	0.49	0.001
cltr1_human	323		C-term	K => R	missense	1.184e-05	1	84470	0	0.33	0.021
cltr1_human	322		C-term	R => G	missense	2.358e-05	2	84801	0	0.11	0.0
cltr1_human	321		C-term	P => A	missense	3.528e-05	3	85036	0	0.79	0.005
cltr1_human	317		C-term	V => M	missense	2.326e-05	2	85980	0	0.71	0.001
cltr1_human	312		C-term	H => Y	missense	1.151e-05	1	86846	0	0.51	0.001
cltr1_human	308	8.56x56	H8	T => A	missense	1.144e-05	1	87379	0	0.21	0.085	PTM (Phosphorylation)
cltr1_human	303	8.51x51	H8	R => T	missense	1.145e-05	1	87372	0	0.0	0.994	GP (contact)
cltr1_human	298	7.56x56	TM7	S => A	missense	1.144e-05	1	87394	0	0.57	0.562	GP (contact)
cltr1_human	297	7.55x55	TM7	F => V	missense	1.144e-05	1	87397	0	0.0	0.979	GP (contact)
cltr1_human	287	7.45x45	TM7	N => S	missense	4.574e-05	4	87450	0	0.0	1.0
cltr1_human	278	7.36x35	TM7	V => I	missense	1.143e-05	1	87461	0	0.05	0.362
cltr1_human	277	7.35x34	TM7	V => L	missense	1.143e-05	1	87461	0	0.05	0.973	LB (hydrophobic)
cltr1_human	277	7.35x34	TM7	V => M	missense	3.43e-05	3	87461	0	0.04	0.999	LB (hydrophobic)
cltr1_human	266	7.24x23	TM7	P => H	missense	1.143e-05	1	87499	0	0.11	0.005
cltr1_human	266	7.24x23	TM7	P => S	missense	4.571e-05	4	87511	0	1.0	0.001
cltr1_human	262	6.64x64	TM6	N => S	missense	1.143e-05	1	87522	0	0.74	0.005
cltr1_human	261	6.63x63	TM6	H => Y	missense	1.143e-05	1	87515	0	0.99	0.334
cltr1_human	259	6.61x61	TM6	F => V	missense	1.143e-05	1	87510	0	0.43	0.035
cltr1_human	253	6.55x55	TM6	R => H	missense	1.143e-05	1	87503	0	0.0	1.0	LB (polar (charge-assisted hydrogen bond))
cltr1_human	251	6.53x53	TM6	I => F	missense	1.143e-05	1	87500	0	0.0	0.936
cltr1_human	245	6.47x47	TM6	S => T	missense	5.717e-05	5	87455	0	0.38	0.613
cltr1_human	243	6.45x46	TM6	L => F	missense	0.0001373	12	87429	0	0.14	0.46
cltr1_human	240	6.42x43	TM6	A => V	missense	1.145e-05	1	87337	0	1.0	0.032
cltr1_human	239	6.41x42	TM6	T => I	missense	1.146e-05	1	87291	0	0.07	0.223
cltr1_human	238	6.40x41	TM6	V => M	missense	4.587e-05	4	87203	0	0.0	0.999
cltr1_human	236	6.38x39	TM6	M => T	missense	1.148e-05	1	87124	0	0.0	0.003
cltr1_human	235	6.37x38	TM6	I => V	missense	1.149e-05	1	87008	0	0.08	0.756
cltr1_human	232	6.34x35	TM6	I => V	missense	1.158e-05	1	86356	0	0.68	0.013
cltr1_human	231	6.33x34	TM6	A => T	missense	2.323e-05	2	86103	0	0.0	0.986	SodiumPocket MicroSwitch
cltr1_human	227	6.29x30	TM6	S => G	missense	2.37e-05	2	84394	0	0.01	0.403	SodiumPocket MicroSwitch
cltr1_human	221		ICL3	M => I	missense	2.42e-05	2	82650	0	0.48	0.039
cltr1_human	219		ICL3	K => N	missense	1.221e-05	1	81886	0	0.68	0.001
cltr1_human	219		ICL3	K => E	missense	1.221e-05	1	81910	0	1.0	0.04
cltr1_human	215	5.64x64	TM5	T => I	missense	1.232e-05	1	81141	0	0.01	0.142	GP (contact)
cltr1_human	214	5.63x63	TM5	L => F	missense	1.237e-05	1	80814	0	0.36	0.005
cltr1_human	212	5.61x61	TM5	I => T	missense	4.958e-05	4	80684	0	0.0	0.999	GP (contact)
cltr1_human	206	5.55x55	TM5	I => S	missense	0.0001751	14	79946	0	0.85	0.297
cltr1_human	199	5.48x48	TM5	I => V	missense	3.761e-05	3	79772	0	0.25	0.074
cltr1_human	198	5.47x47	TM5	F => C	missense	1.253e-05	1	79789	0	0.03	0.833	SodiumPocket MicroSwitch
cltr1_human	198	5.47x47	TM5	F => S	missense	1.253e-05	1	79789	0	0.0	0.994	SodiumPocket MicroSwitch
cltr1_human	191	5.40x41	TM5	Y => F	missense	1.242e-05	1	80537	0	0.15	0.651
cltr1_human	188	5.37x38	TM5	V => I	missense	1.233e-05	1	81108	0	0.93	0.012
cltr1_human	184	5.33x34	TM5	N => Y	missense	2.444e-05	2	81828	0	0.08	0.005
cltr1_human	176		ECL2	P => L	missense	4.818e-05	4	83020	0	1.0	0.998
cltr1_human	165		ECL2	K => E	missense	2.396e-05	2	83488	0	0.45	0.014
cltr1_human	163		ECL2	P => L	missense	1.198e-05	1	83439	0	0.32	0.001
cltr1_human	163		ECL2	P => T	missense	1.198e-05	1	83482	0	0.82	0.001
cltr1_human	161	4.63x64	TM4	A => T	missense	2.397e-05	2	83423	0	0.41	0.001
cltr1_human	161	4.63x64	TM4	A => P	missense	2.397e-05	2	83423	0	0.07	0.167
cltr1_human	160	4.62x63	TM4	M => I	missense	3.591e-05	3	83551	0	0.15	0.026
cltr1_human	152	4.54x54	TM4	I => N	missense	7.14e-05	6	84031	0	0.03	0.281
cltr1_human	152	4.54x54	TM4	I => F	missense	7.139e-05	6	84040	0	0.03	0.532
cltr1_human	143	4.45x45	TM4	V => L	missense	1.179e-05	1	84850	0	0.3	0.06
cltr1_human	135	34.57x57	ICL2	V => I	missense	1.171e-05	1	85369	0	0.3	0.015	GP (contact)
cltr1_human	123	3.52x52	TM3	I => T	missense	0.0007123	61	85642	0	0.0	0.143
cltr1_human	122	3.51x51	TM3	C => Y	missense	1.168e-05	1	85638	0	0.64	0.048
cltr1_human	121	3.50x50	TM3	R => Q	missense	4.673e-05	4	85593	0	0.0	1.0	SodiumPocket MicroSwitch GP (contact)
cltr1_human	121	3.50x50	TM3	R => P	missense	1.168e-05	1	85593	0	0.0	1.0	SodiumPocket MicroSwitch GP (contact)
cltr1_human	121	3.50x50	TM3	R => W	missense	1.168e-05	1	85602	0	0.0	1.0	SodiumPocket MicroSwitch GP (contact)
cltr1_human	117	3.46x46	TM3	M => T	missense	1.167e-05	1	85689	0	0.0	0.985
cltr1_human	113	3.42x42	TM3	F => L	missense	1.168e-05	1	85651	0	0.07	0.576
cltr1_human	102	3.31x31	TM3	A => V	missense	2.336e-05	2	85602	0	0.05	0.261
cltr1_human	101	3.30x30	TM3	Y => S	missense	1.168e-05	1	85652	0	0.0	0.998
cltr1_human	97	3.26x26	TM3	R => H	missense	8.18e-05	7	85571	0	0.0	1.0
cltr1_human	90	23.51x51	ECL1	L => V	missense	1.164e-05	1	85890	0	0.52	0.005
cltr1_human	79	2.60x60	TM2	R => H	missense	1.159e-05	1	86248	0	0.0	1.0
cltr1_human	79	2.60x60	TM2	R => L	missense	1.159e-05	1	86248	0	0.0	1.0
cltr1_human	79	2.60x60	TM2	R => C	missense	1.159e-05	1	86277	0	0.0	1.0
cltr1_human	74	2.55x55	TM2	C => S	missense	2.308e-05	2	86646	0	0.65	0.159
cltr1_human	72	2.53x53	TM2	C => Y	missense	1.154e-05	1	86686	0	0.45	0.898
cltr1_human	70	2.51x51	TM2	L => Q	missense	1.152e-05	1	86774	0	0.0	0.964
cltr1_human	68	2.49x49	TM2	A => T	missense	2.303e-05	2	86851	0	0.0	0.528
cltr1_human	61	2.42x42	TM2	Y => C	missense	2.297e-05	2	87057	0	0.0	0.599
cltr1_human	60	2.41x41	TM2	V => I	missense	1.148e-05	1	87085	0	0.63	0.045
cltr1_human	55		ICL1	K => Q	missense	1.147e-05	1	87204	0	0.07	0.827
cltr1_human	47	1.56x56	TM1	V => F	missense	1.146e-05	1	87261	0	0.0	0.883
cltr1_human	29	1.38x38	TM1	L => F	missense	1.148e-05	1	87088	0	0.21	0.006
cltr1_human	23	1.32x32	TM1	N => S	missense	1.154e-05	1	86628	0	0.19	0.186
cltr1_human	22	1.31x31	TM1	R => H	missense	8.098e-05	7	86441	0	0.0	0.978
cltr1_human	22	1.31x31	TM1	R => C	missense	1.157e-05	1	86435	0	0.0	0.99
cltr1_human	20	1.29x29	TM1	D => G	missense	1.16e-05	1	86185	0	0.02	0.358
cltr1_human	17	1.26x26	TM1	T => I	missense	1.166e-05	1	85787	0	0.01	0.066
cltr1_human	10		N-term	S => P	missense	3.555e-05	3	84390	0	0.21	0.001	PTM (Phosphorylation)
cltr1_human	8		N-term	T => A	missense	1.19e-05	1	84057	0	0.19	0.391	PTM (Phosphorylation)
cltr1_human	8		N-term	T => P	missense	1.19e-05	1	84057	0	0.03	0.112	PTM (Phosphorylation)

Residue

deleterious missense variants are shown in red
tolerated missense variants are shown in green
loss of function mutations ('stop gained' or 'frameshift' in the coding region) are shown in blue

Diagrams

SnakePlot Download: PNG | SVG
HelixBox Download: PNG | SVG

Package	Name	Version
Django		2.2.1
Python		3.6.7
debug_toolbar	Debug Toolbar	1.11
polymorphic	Polymorphic	2.0.3
rest_framework	Django REST framework	3.9.3
rest_framework_swagger	Rest_Framework_Swagger	2.2.0

Resource	Value
User CPU time	2948.634 msec
System CPU time	68.002 msec
Total CPU time	3016.636 msec
Elapsed time	3292.676 msec
Context switches	144 voluntary, 20 involuntary

Setting	Value
ABSOLUTE_URL_OVERRIDES	`{}`
ADMINS	`[]`
ALLOWED_HOSTS	`['*']`
APPEND_SLASH	`True`
AUTHENTICATION_BACKENDS	`['django.contrib.auth.backends.ModelBackend']`
AUTH_PASSWORD_VALIDATORS	`'********************'`
AUTH_USER_MODEL	`'auth.User'`
BASE_DIR	`'/home/protwis/gpcrdb_test'`
BUILD_CACHE_DIR	`'/home/protwis/gpcrdb_data/cache'`
CACHES	`{'alignments': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test_alignment', 'OPTIONS': {'MAX_ENTRIES': 1000}}, 'default': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test/', 'OPTIONS': {'MAX_ENTRIES': 10000000}}}`
CACHE_MIDDLEWARE_ALIAS	`'default'`
CACHE_MIDDLEWARE_KEY_PREFIX	`'********************'`
CACHE_MIDDLEWARE_SECONDS	`600`
CSRF_COOKIE_AGE	`31449600`
CSRF_COOKIE_DOMAIN	`None`
CSRF_COOKIE_HTTPONLY	`False`
CSRF_COOKIE_NAME	`'csrftoken'`
CSRF_COOKIE_PATH	`'/'`
CSRF_COOKIE_SAMESITE	`'Lax'`
CSRF_COOKIE_SECURE	`False`
CSRF_FAILURE_VIEW	`'django.views.csrf.csrf_failure'`
CSRF_HEADER_NAME	`'HTTP_X_CSRFTOKEN'`
CSRF_TRUSTED_ORIGINS	`[]`
CSRF_USE_SESSIONS	`False`
DATABASES	`{'default': {'ATOMIC_REQUESTS': False, 'AUTOCOMMIT': True, 'CONN_MAX_AGE': 0, 'ENGINE': 'django.db.backends.postgresql_psycopg2', 'HOST': 'localhost', 'NAME': 'protwis_202107', 'OPTIONS': {}, 'PASSWORD': '********************', 'PORT': '', 'TEST': {'CHARSET': None, 'COLLATION': None, 'MIRROR': None, 'NAME': None}, 'TIME_ZONE': None, 'USER': 'protwis'}}`
DATABASE_ROUTERS	`[]`
DATA_DIR	`'/home/protwis/gpcrdb_data'`
DATA_UPLOAD_MAX_MEMORY_SIZE	`2621440`
DATA_UPLOAD_MAX_NUMBER_FIELDS	`1000`
DATETIME_FORMAT	`'N j, Y, P'`
DATETIME_INPUT_FORMATS	`['%Y-%m-%d %H:%M:%S', '%Y-%m-%d %H:%M:%S.%f', '%Y-%m-%d %H:%M', '%Y-%m-%d', '%m/%d/%Y %H:%M:%S', '%m/%d/%Y %H:%M:%S.%f', '%m/%d/%Y %H:%M', '%m/%d/%Y', '%m/%d/%y %H:%M:%S', '%m/%d/%y %H:%M:%S.%f', '%m/%d/%y %H:%M', '%m/%d/%y']`
DATE_FORMAT	`'N j, Y'`
DATE_INPUT_FORMATS	`['%Y-%m-%d', '%m/%d/%Y', '%m/%d/%y', '%b %d %Y', '%b %d, %Y', '%d %b %Y', '%d %b, %Y', '%B %d %Y', '%B %d, %Y', '%d %B %Y', '%d %B, %Y']`
DEBUG	`True`
DEBUG_PROPAGATE_EXCEPTIONS	`False`
DEBUG_TOOLBAR_PATCH_SETTINGS	`False`
DECIMAL_SEPARATOR	`'.'`
DEFAULT_CHARSET	`'utf-8'`
DEFAULT_CONTENT_TYPE	`'text/html'`
DEFAULT_EXCEPTION_REPORTER_FILTER	`'django.views.debug.SafeExceptionReporterFilter'`
DEFAULT_FILE_STORAGE	`'django.core.files.storage.FileSystemStorage'`
DEFAULT_FROM_EMAIL	`'webmaster@localhost'`
DEFAULT_INDEX_TABLESPACE	`''`
DEFAULT_NUMBERING_SCHEME	`'gpcrdb'`
DEFAULT_PROTEIN_STATE	`'inactive'`
DEFAULT_SITE	`'gpcr'`
DEFAULT_TABLESPACE	`''`
DISALLOWED_USER_AGENTS	`[]`
DOCUMENTATION_URL	`'https://docs.gpcrdb.org/'`
EMAIL_BACKEND	`'django.core.mail.backends.smtp.EmailBackend'`
EMAIL_HOST	`'localhost'`
EMAIL_HOST_PASSWORD	`'********************'`
EMAIL_HOST_USER	`''`
EMAIL_PORT	`25`
EMAIL_SSL_CERTFILE	`None`
EMAIL_SSL_KEYFILE	`'********************'`
EMAIL_SUBJECT_PREFIX	`'[Django] '`
EMAIL_TIMEOUT	`None`
EMAIL_USE_LOCALTIME	`False`
EMAIL_USE_SSL	`False`
EMAIL_USE_TLS	`False`
FILE_CHARSET	`'utf-8'`
FILE_UPLOAD_DIRECTORY_PERMISSIONS	`None`
FILE_UPLOAD_HANDLERS	`['django.core.files.uploadhandler.MemoryFileUploadHandler', 'django.core.files.uploadhandler.TemporaryFileUploadHandler']`
FILE_UPLOAD_MAX_MEMORY_SIZE	`2621440`
FILE_UPLOAD_PERMISSIONS	`None`
FILE_UPLOAD_TEMP_DIR	`None`
FIRST_DAY_OF_WEEK	`0`
FIXTURE_DIRS	`[]`
FORCE_SCRIPT_NAME	`None`
FORMAT_MODULE_PATH	`None`
FORM_RENDERER	`'django.forms.renderers.DjangoTemplates'`
GOOGLE_ANALYTICS_API	`'********************'`
GOOGLE_ANALYTICS_KEY	`'********************'`
IGNORABLE_404_URLS	`[]`
INSTALLED_APPS	('django.contrib.admin', 'django.contrib.auth', 'django.contrib.contenttypes', 'django.contrib.sessions', 'django.contrib.messages', 'django.contrib.staticfiles', 'django.contrib.humanize', 'debug_toolbar', 'rest_framework', 'rest_framework_swagger', 'polymorphic', 'common', 'api', 'news', 'pages', 'home', 'protein', 'family', 'residue', 'alignment', 'similaritysearch', 'similaritymatrix', 'structure', 'ligand', 'interaction', 'mutation', 'phylogenetic_trees', 'sitesearch', 'build_gpcr', 'construct', 'tools', 'drugs', 'signprot', 'signprot2', 'mutational_landscape', 'contactnetwork', 'seqsign', 'angles', 'hotspots')
INTERNAL_IPS	`'10.0.2.2'`
LANGUAGES	[('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')]
LANGUAGES_BIDI	`['he', 'ar', 'fa', 'ur']`
LANGUAGE_CODE	`'en-us'`
LANGUAGE_COOKIE_AGE	`None`
LANGUAGE_COOKIE_DOMAIN	`None`
LANGUAGE_COOKIE_NAME	`'django_language'`
LANGUAGE_COOKIE_PATH	`'/'`
LOCALE_PATHS	`[]`
LOGGING	{'disable_existing_loggers': False, 'formatters': {'verbose': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s] %(message)s'}, 'verbose_low': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s]'}}, 'handlers': {'build': {'class': 'logging.FileHandler', 'filename': 'logs/build.log', 'formatter': 'verbose', 'level': 'DEBUG'}, 'django': {'class': 'logging.FileHandler', 'filename': 'logs/django.log', 'formatter': 'verbose', 'level': 'WARNING'}, 'protwis': {'class': 'logging.FileHandler', 'filename': 'logs/protwis.log', 'formatter': 'verbose', 'level': 'DEBUG'}}, 'loggers': {'build': {'handlers': ['build'], 'level': 'DEBUG'}, 'django': {'handlers': ['django'], 'level': 'WARNING', 'propagate': True}, 'protwis': {'handlers': ['protwis'], 'level': 'DEBUG'}}, 'version': 1}
LOGGING_CONFIG	`'logging.config.dictConfig'`
LOGIN_REDIRECT_URL	`'/accounts/profile/'`
LOGIN_URL	`'/accounts/login/'`
LOGOUT_REDIRECT_URL	`None`
MANAGERS	`[]`
MEDIA_ROOT	`'/protwis/media/protwis'`
MEDIA_URL	`'/media/'`
MESSAGE_STORAGE	`'django.contrib.messages.storage.fallback.FallbackStorage'`
MIDDLEWARE	`('common.middleware.stats.StatsMiddleware', 'debug_toolbar.middleware.DebugToolbarMiddleware', 'django.contrib.sessions.middleware.SessionMiddleware', 'django.middleware.common.CommonMiddleware', 'django.middleware.csrf.CsrfViewMiddleware', 'django.contrib.auth.middleware.AuthenticationMiddleware', 'django.contrib.messages.middleware.MessageMiddleware', 'django.middleware.clickjacking.XFrameOptionsMiddleware')`
MIGRATION_MODULES	`{}`
MONTH_DAY_FORMAT	`'F j'`
NUMBER_GROUPING	`0`
PASSWORD_HASHERS	`'********************'`
PASSWORD_RESET_TIMEOUT_DAYS	`'********************'`
PREPEND_WWW	`False`
REFERENCE_POSITIONS	`{'D1S1': 'D1S1x50', 'D1S2': 'D1S2x50', 'D1T1': 'D1T1x50', 'D1e1': 'D1e1x50', 'ECL1': '23x50', 'ECL2': '45x50', 'H8': '8x50', 'ICL1': '12x50', 'ICL2': '34x50', 'TM1': '1x50', 'TM2': '2x50', 'TM3': '3x50', 'TM4': '4x50', 'TM5': '5x50', 'TM6': '6x50', 'TM7': '7x50'}`
ROOT_URLCONF	`'protwis.urls'`
SECRET_KEY	`'********************'`
SECURE_BROWSER_XSS_FILTER	`False`
SECURE_CONTENT_TYPE_NOSNIFF	`False`
SECURE_HSTS_INCLUDE_SUBDOMAINS	`False`
SECURE_HSTS_PRELOAD	`False`
SECURE_HSTS_SECONDS	`0`
SECURE_PROXY_SSL_HEADER	`None`
SECURE_REDIRECT_EXEMPT	`[]`
SECURE_SSL_HOST	`None`
SECURE_SSL_REDIRECT	`False`
SERVER_EMAIL	`'root@localhost'`
SESSION_CACHE_ALIAS	`'default'`
SESSION_COOKIE_AGE	`86400`
SESSION_COOKIE_DOMAIN	`None`
SESSION_COOKIE_HTTPONLY	`True`
SESSION_COOKIE_NAME	`'sessionid'`
SESSION_COOKIE_PATH	`'/'`
SESSION_COOKIE_SAMESITE	`'Lax'`
SESSION_COOKIE_SECURE	`False`
SESSION_ENGINE	`'django.contrib.sessions.backends.db'`
SESSION_EXPIRE_AT_BROWSER_CLOSE	`False`
SESSION_FILE_PATH	`None`
SESSION_SAVE_EVERY_REQUEST	`False`
SESSION_SERIALIZER	`'django.contrib.sessions.serializers.PickleSerializer'`
SETTINGS_MODULE	`'protwis.settings'`
SHORT_DATETIME_FORMAT	`'m/d/Y P'`
SHORT_DATE_FORMAT	`'m/d/Y'`
SIGNING_BACKEND	`'django.core.signing.TimestampSigner'`
SILENCED_SYSTEM_CHECKS	`[]`
SITE_NAME	`'gpcr'`
SITE_TITLE	`'GPCRdb'`
STATICFILES_DIRS	`('/home/protwis/gpcrdb_test/static',)`
STATICFILES_FINDERS	`['django.contrib.staticfiles.finders.FileSystemFinder', 'django.contrib.staticfiles.finders.AppDirectoriesFinder']`
STATICFILES_STORAGE	`'django.contrib.staticfiles.storage.StaticFilesStorage'`
STATIC_ROOT	`'/home/protwis/static_test/'`
STATIC_URL	`'/static/'`
SWAGGER_SETTINGS	`{'USE_SESSION_AUTH': False}`
TEMPLATES	[{'APP_DIRS': True, 'BACKEND': 'django.template.backends.django.DjangoTemplates', 'DIRS': [], 'OPTIONS': {'context_processors': ['django.contrib.auth.context_processors.auth', 'django.template.context_processors.debug', 'django.template.context_processors.i18n', 'django.template.context_processors.media', 'django.template.context_processors.static', 'django.template.context_processors.tz', 'django.contrib.messages.context_processors.messages', 'protwis.context_processors.current_site', 'protwis.context_processors.canonical_tag', 'protwis.context_processors.documentation_url', 'protwis.context_processors.google_analytics', 'protwis.context_processors.site_title'], 'debug': True}}]
TEST_NON_SERIALIZED_APPS	`[]`
TEST_RUNNER	`'django.test.runner.DiscoverRunner'`
THOUSAND_SEPARATOR	`','`
TIME_FORMAT	`'P'`
TIME_INPUT_FORMATS	`['%H:%M:%S', '%H:%M:%S.%f', '%H:%M']`
TIME_ZONE	`'Europe/Copenhagen'`
USE_I18N	`True`
USE_L10N	`True`
USE_THOUSAND_SEPARATOR	`False`
USE_TZ	`True`
USE_X_FORWARDED_HOST	`False`
USE_X_FORWARDED_PORT	`False`
WSGI_APPLICATION	`None`
X_FRAME_OPTIONS	`'SAMEORIGIN'`
YEAR_MONTH_FORMAT	`'F Y'`

Key	Value
Accept	text/html,application/xhtml+xml,application/xml;q=0.9,/;q=0.8
Accept-Encoding	br,gzip
Accept-Language	en-US,en;q=0.5
Connection	close
Host	test.gpcrdb.org
User-Agent	CCBot/2.0 (https://commoncrawl.org/faq/)
X-Forwarded-For	3.236.207.90
X-Forwarded-Proto	https
X-Real-Ip	3.236.207.90

Key	Value
Content-Length	464401
Content-Type	text/html; charset=utf-8
Vary	Cookie
X-Frame-Options	SAMEORIGIN

Variation Browser

Residue

Diagrams

Versions

Time

Resource usage

Browser timing

Settings from `protwis.settings`

Headers

Request headers

Response headers

WSGI environ

Request

View information

No cookies

No session data

No GET data

No POST data

SQL queries from 1 connection

Key	Value
PATH_INFO	/mutational_landscape/protein/CLTR1_human/
QUERY_STRING
REMOTE_ADDR
REQUEST_METHOD	GET
SCRIPT_NAME
SERVER_NAME	test.gpcrdb.org
SERVER_PORT	443
SERVER_PROTOCOL	HTTP/1.0
SERVER_SOFTWARE	gunicorn/19.9.0

Query		Timeline	Time (ms)
+	SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 'cltr1_human'	0.9473452302269222%	2.67
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89) proteins.append(Protein.objects.get(entry_name=protein.lower()))
+	SELECT ••• "residue_position_set"."id", "residue_position_set"."name", "residue_position_set"."set_type", "residue_position_set"."protein_group" FROM "residue_position_set" WHERE "residue_position_set"."name" = 'State (micro-)switches' 3 similar queries.	0.20260308099039098%	0.57
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(128) micro_switches_rset = ResiduePositionSet.objects.get(name="State (micro-)switches")
+	SELECT ••• "residue_generic_number_equivalent"."id", "residue_generic_number_equivalent"."default_generic_number_id", "residue_generic_number_equivalent"."scheme_id", "residue_generic_number_equivalent"."label" FROM "residue_generic_number_equivalent" INNER JOIN "residue_position_set_residue_position" ON ("residue_generic_number_equivalent"."id" = "residue_position_set_residue_position"."residuegenericnumberequivalent_id") WHERE "residue_position_set_residue_position"."residuepositionset_id" = 2 3 similar queries.	0.6529733760401308%	1.84
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(130) for residue in micro_switches_rset.residue_position.all():
+	SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" INNER JOIN "residue_generic_number" ON ("residue"."generic_number_id" = "residue_generic_number"."id") INNER JOIN "protein_conformation" ON ("residue"."protein_conformation_id" = "protein_conformation"."id") WHERE ("residue_generic_number"."label" IN ('5x47', '5x50', '6x30', '6x44', '6x50', '6x48', '6x34', '5x58', '3x40', '3x49', '3x50', '7x53', '7x50', '7x49', '7x43') AND "protein_conformation"."protein_id" = 149) ORDER BY "residue"."sequence_number" ASC 2 similar queries. Duplicated 2 times.	2.7517074245428508%	7.74
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(135) for ms in ms_object:
+	SELECT ••• "residue_position_set"."id", "residue_position_set"."name", "residue_position_set"."set_type", "residue_position_set"."protein_group" FROM "residue_position_set" WHERE "residue_position_set"."name" = 'Sodium ion pocket' 3 similar queries.	0.12049417865676952%	0.34
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(139) sodium_pocket_rset = ResiduePositionSet.objects.get(name="Sodium ion pocket")
+	SELECT ••• "residue_generic_number_equivalent"."id", "residue_generic_number_equivalent"."default_generic_number_id", "residue_generic_number_equivalent"."scheme_id", "residue_generic_number_equivalent"."label" FROM "residue_generic_number_equivalent" INNER JOIN "residue_position_set_residue_position" ON ("residue_generic_number_equivalent"."id" = "residue_position_set_residue_position"."residuegenericnumberequivalent_id") WHERE "residue_position_set_residue_position"."residuepositionset_id" = 3 3 similar queries.	0.3737692138220889%	1.05
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(141) for residue in sodium_pocket_rset.residue_position.all():
+	SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" INNER JOIN "residue_generic_number" ON ("residue"."generic_number_id" = "residue_generic_number"."id") INNER JOIN "protein_conformation" ON ("residue"."protein_conformation_id" = "protein_conformation"."id") WHERE ("residue_generic_number"."label" IN ('5x47', '5x50', '6x30', '6x44', '6x50', '6x48', '6x34', '5x58', '3x40', '3x49', '3x50', '7x53', '7x50', '7x49', '7x43') AND "protein_conformation"."protein_id" = 149) ORDER BY "residue"."sequence_number" ASC 2 similar queries. Duplicated 2 times.	0.4413883098615418%	1.24
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(146) for sp in sp_object:
+	SELECT ••• "residue_ptm"."id", "residue_ptm"."protein_id", "residue_ptm"."residue_id", "residue_ptm"."modification" FROM "residue_ptm" WHERE "residue_ptm"."protein_id" IN (149)	0.2178555086684631%	0.61
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(149) for ptm in ptms:
+	SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" WHERE "residue"."id" IN (64577, 64584, 64266, 64268, 64565, 64566, 64571, 64573, 64574) ORDER BY "residue"."sequence_number" ASC	0.8587964139847813%	2.42
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(149) for ptm in ptms:
+	SELECT ••• "residue_position_set"."id", "residue_position_set"."name", "residue_position_set"."set_type", "residue_position_set"."protein_group" FROM "residue_position_set" WHERE "residue_position_set"."name" = 'G-protein interface' 3 similar queries.	0.12049417865676952%	0.34
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(154) rset = ResiduePositionSet.objects.get(name='G-protein interface')
+	SELECT ••• "residue_generic_number_equivalent"."id", "residue_generic_number_equivalent"."default_generic_number_id", "residue_generic_number_equivalent"."scheme_id", "residue_generic_number_equivalent"."label" FROM "residue_generic_number_equivalent" INNER JOIN "residue_position_set_residue_position" ON ("residue_generic_number_equivalent"."id" = "residue_position_set_residue_position"."residuegenericnumberequivalent_id") WHERE "residue_position_set_residue_position"."residuepositionset_id" = 1 3 similar queries.	0.3722439710542817%	1.05
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(156) for residue in rset.residue_position.all():
+	SELECT ••• "protein_family"."id", "protein_family"."parent_id", "protein_family"."slug", "protein_family"."name" FROM "protein_family" WHERE "protein_family"."id" = 201	0.20480620943277913%	0.58
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(163) orthologs = Protein.objects.filter(family__slug=proteins[0].family.slug, sequence_type__slug='wt')
+	SELECT ••• "interaction_residue_fragment"."id", "interaction_residue_fragment"."structure_ligand_pair_id", "interaction_residue_fragment"."rotamer_id", "interaction_residue_fragment"."fragment_id", "interaction_residue_fragment"."interaction_type_id" FROM "interaction_residue_fragment" INNER JOIN "interaction_structure_ligand" ON ("interaction_residue_fragment"."structure_ligand_pair_id" = "interaction_structure_ligand"."id") INNER JOIN "structure" ON ("interaction_structure_ligand"."structure_id" = "structure"."id") INNER JOIN "protein_conformation" ON ("structure"."protein_conformation_id" = "protein_conformation"."id") INNER JOIN "protein" ON ("protein_conformation"."protein_id" = "protein"."id") INNER JOIN "interaction_type_residue_fragment" ON ("interaction_residue_fragment"."interaction_type_id" = "interaction_type_residue_fragment"."id") WHERE ("interaction_structure_ligand"."annotated" = true AND "protein"."parent_id" IN (SELECT ••• U0."id" FROM "protein" U0 INNER JOIN "protein_family" U1 ON (U0."family_id" = U1."id") INNER JOIN "protein_sequence_type" U2 ON (U0."sequence_type_id" = U2."id") WHERE (U1."slug" = '001_004_002_003' AND U2."slug" = 'wt')) AND NOT ("interaction_type_residue_fragment"."type" = 'hidden' AND "interaction_type_residue_fragment"."type" IS NOT NULL))	71.95739488535258%	202.46
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(170) for interaction in interactions:
+	SELECT ••• "structure_rotamer"."id", "structure_rotamer"."residue_id", "structure_rotamer"."structure_id", "structure_rotamer"."pdbdata_id", "structure_rotamer"."missing_atoms" FROM "structure_rotamer" WHERE "structure_rotamer"."id" = 32490 21 similar queries.	0.9403969020624672%	2.65
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(171) if interaction.rotamer.residue.generic_number:
+	SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" WHERE "residue"."id" = 23593086 21 similar queries. Duplicated 3 times.	0.7688918263934788%	2.16
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(171) if interaction.rotamer.residue.generic_number:
+	SELECT ••• "residue_generic_number"."id", "residue_generic_number"."scheme_id", "residue_generic_number"."protein_segment_id", "residue_generic_number"."label" FROM "residue_generic_number" WHERE "residue_generic_number"."id" = 30722 20 similar queries. Duplicated 6 times.	0.16218414764349992%	0.46
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(171) if interaction.rotamer.residue.generic_number:
+	SELECT ••• "interaction_type_residue_fragment"."id", "interaction_type_residue_fragment"."slug", "interaction_type_residue_fragment"."name", "interaction_type_residue_fragment"."type", "interaction_type_residue_fragment"."direction" FROM "interaction_type_residue_fragment" WHERE "interaction_type_residue_fragment"."id" = 9 20 similar queries. Duplicated 4 times.	0.14100022031284426%	0.40
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(176) interactiontype = interaction.interaction_type.name
+	SELECT ••• "structure_rotamer"."id", "structure_rotamer"."residue_id", "structure_rotamer"."structure_id", "structure_rotamer"."pdbdata_id", "structure_rotamer"."missing_atoms" FROM "structure_rotamer" WHERE "structure_rotamer"."id" = 32494 21 similar queries.	0.13583134204416425%	0.38
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(171) if interaction.rotamer.residue.generic_number:
+	SELECT ••• "residue"."id", "residue"."protein_conformation_id", "residue"."protein_segment_id", "residue"."generic_number_id", "residue"."display_generic_number_id", "residue"."sequence_number", "residue"."amino_acid" FROM "residue" WHERE "residue"."id" = 23593090 21 similar queries.	0.13600081346280948%	0.38
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(171) if interaction.rotamer.residue.generic_number:
+	SELECT ••• "residue_generic_number"."id", "residue_generic_number"."scheme_id", "residue_generic_number"."protein_segment_id", "residue_generic_number"."label" FROM "residue_generic_number" WHERE "residue_generic_number"."id" = 32386 20 similar queries. Duplicated 2 times.	0.12854407104241872%	0.36
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(171) if interaction.rotamer.residue.generic_number:

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