GPCRdb

Variation Browser

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Receptor	Position	GPCRdb	Segment	Variant	Mutation type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation


Receptor	Position	GPCRdb	Segment	Variant	Mutation Type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation
cnr1_human	405	8.51x51	H8	R => Ter	stop gained	8.239e-06	1	121376	0	None	None	GP (contact)
cnr1_human	47		N-term	K => Ter	stop gained	1.648e-05	2	121390	0	None	None
cnr1_human	20		N-term	L => Ter	stop gained	2.472e-05	3	121378	0	None	None
cnr1_human	471		C-term	A => S	missense	8.309e-06	1	120358	0	nan	0.888
cnr1_human	463		C-term	V => A	missense	8.257e-06	1	121114	0	1.0	0.338
cnr1_human	462		C-term	S => F	missense	8.254e-06	1	121158	0	0.01	0.959
cnr1_human	452		C-term	S => T	missense	8.237e-06	1	121402	0	0.8	0.003
cnr1_human	450		C-term	I => T	missense	8.237e-06	1	121402	0	0.36	0.108
cnr1_human	446		C-term	A => T	missense	8.237e-06	1	121406	0	0.18	0.843
cnr1_human	446		C-term	A => S	missense	8.237e-06	1	121406	0	0.18	0.829
cnr1_human	444		C-term	R => G	missense	8.236e-06	1	121412	0	0.09	0.086
cnr1_human	442		C-term	V => G	missense	3.295e-05	4	121412	0	0.38	0.033
cnr1_human	436		C-term	A => T	missense	7.413e-05	9	121412	0	0.32	0.005
cnr1_human	435		C-term	H => Y	missense	8.236e-06	1	121412	0	0.06	0.126
cnr1_human	431		C-term	C => Y	missense	8.236e-06	1	121412	0	0.19	0.312
cnr1_human	423		C-term	D => N	missense	2.471e-05	3	121404	0	0.04	0.962
cnr1_human	419		C-term	A => E	missense	0.0003789	46	121400	0	0.33	0.22
cnr1_human	419		C-term	A => V	missense	1.647e-05	2	121400	0	0.22	0.104
cnr1_human	417		C-term	G => C	missense	8.237e-06	1	121398	0	0.0	0.974
cnr1_human	416		C-term	E => K	missense	8.237e-06	1	121398	0	0.48	0.004
cnr1_human	412	8.58x58	H8	F => C	missense	4.119e-05	5	121392	0	0.21	0.004
cnr1_human	410	8.56x56	H8	S => N	missense	8.238e-06	1	121386	0	0.83	0.007
cnr1_human	409	8.55x55	H8	R => Q	missense	1.648e-05	2	121384	0	0.36	0.201
cnr1_human	409	8.55x55	H8	R => W	missense	8.238e-06	1	121384	0	0.05	0.635
cnr1_human	407	8.53x53	H8	A => T	missense	3.295e-05	4	121378	0	0.01	0.999
cnr1_human	364	6.56x56	TM6	V => M	missense	8.265e-06	1	120986	0	0.04	0.815
cnr1_human	352	6.44x44	TM6	L => V	missense	8.291e-06	1	120612	0	0.03	0.999	SodiumPocket MicroSwitch
cnr1_human	351	6.43x43	TM6	V => L	missense	2.488e-05	3	120564	0	0.01	0.728
cnr1_human	340	6.32x32	TM6	R => M	missense	1.664e-05	2	120228	0	0.14	1.0	GP (contact)
cnr1_human	337	6.29x29	TM6	M => V	missense	1.664e-05	2	120190	0	0.0	0.994	GP (contact)
cnr1_human	336	6.28x28	TM6	R => C	missense	8.323e-06	1	120148	0	0.0	1.0	GP (contact)
cnr1_human	331		ICL3	R => Q	missense	8.331e-06	1	120038	0	0.19	0.999
cnr1_human	331		ICL3	R => W	missense	8.331e-06	1	120032	0	0.01	1.0
cnr1_human	328		ICL3	Q => E	missense	8.33e-06	1	120052	0	0.06	0.209
cnr1_human	326		ICL3	K => N	missense	8.331e-06	1	120038	0	0.06	0.99
cnr1_human	321		ICL3	T => K	missense	2.498e-05	3	120082	0	0.04	0.41
cnr1_human	321		ICL3	T => M	missense	4.164e-05	5	120082	0	0.01	0.832
cnr1_human	318		ICL3	I => S	missense	2.498e-05	3	120116	0	0.01	0.88
cnr1_human	317		ICL3	I => M	missense	8.325e-06	1	120124	0	0.38	0.071
cnr1_human	317		ICL3	I => V	missense	8.324e-06	1	120130	0	0.53	0.007
cnr1_human	312	5.76x76	TM5	G => D	missense	8.322e-06	1	120168	0	0.2	0.601
cnr1_human	311	5.75x75	TM5	R => H	missense	8.32e-06	1	120188	0	0.25	1.0	GP (contact)
cnr1_human	311	5.75x75	TM5	R => C	missense	8.32e-06	1	120192	0	0.0	1.0	GP (contact)
cnr1_human	307	5.71x71	TM5	R => H	missense	2.496e-05	3	120216	0	0.08	0.115	GP (contact)
cnr1_human	307	5.71x71	TM5	R => C	missense	8.318e-06	1	120216	0	0.08	0.97	GP (contact)
cnr1_human	306	5.70x70	TM5	V => I	missense	4.159e-05	5	120228	0	0.06	0.932
cnr1_human	305	5.69x69	TM5	A => T	missense	2.495e-05	3	120250	0	0.23	0.733	GP (contact)
cnr1_human	299	5.63x63	TM5	W => R	missense	8.309e-06	1	120350	0	0.02	1.0
cnr1_human	293	5.57x57	TM5	A => V	missense	8.306e-06	1	120400	0	0.0	1.0
cnr1_human	291	5.55x55	TM5	V => L	missense	4.152e-05	5	120434	0	0.19	0.327
cnr1_human	285	5.49x49	TM5	V => I	missense	0.0001494	18	120522	0	0.58	0.016
cnr1_human	274	5.38x38	TM5	T => S	missense	1.658e-05	2	120636	0	0.5	0.122
cnr1_human	271		ECL2	I => T	missense	8.288e-06	1	120656	0	0.0	0.999
cnr1_human	249	4.58x58	TM4	V => M	missense	8.279e-06	1	120790	0	0.13	0.954
cnr1_human	248	4.57x57	TM4	A => T	missense	8.277e-06	1	120816	0	0.01	0.754
cnr1_human	243	4.52x52	TM4	I => M	missense	8.273e-06	1	120876	0	0.02	0.938
cnr1_human	243	4.52x52	TM4	I => T	missense	8.274e-06	1	120864	0	0.37	0.932
cnr1_human	239	4.48x48	TM4	L => M	missense	8.274e-06	1	120860	0	0.41	0.018
cnr1_human	234	4.43x43	TM4	V => M	missense	8.279e-06	1	120790	0	0.12	0.991
cnr1_human	231	4.40x40	TM4	P => T	missense	8.279e-06	1	120782	0	0.61	0.003
cnr1_human	229	4.38x38	TM4	T => S	missense	8.279e-06	1	120788	0	0.0	0.999
cnr1_human	186	3.22x22	TM3	R => L	missense	8.293e-06	1	120588	0	0.03	0.076
cnr1_human	185	3.21x21	TM3	S => N	missense	5.804e-05	7	120608	0	0.04	0.974
cnr1_human	179	2.66x66	TM2	V => M	missense	8.292e-06	1	120596	0	0.0	0.997
cnr1_human	168	2.55x55	TM2	V => A	missense	1.659e-05	2	120570	0	0.06	0.821
cnr1_human	164	2.51x51	TM2	L => F	missense	2.489e-05	3	120540	0	0.32	1.0
cnr1_human	160	2.47x47	TM2	A => V	missense	8.318e-06	1	120214	0	0.0	1.0
cnr1_human	157	2.44x44	TM2	G => S	missense	3.324e-05	4	120352	0	0.45	0.261
cnr1_human	157	2.44x44	TM2	G => R	missense	8.309e-06	1	120352	0	0.0	0.959
cnr1_human	151	2.38x38	TM2	P => A	missense	1.659e-05	2	120534	0	0.0	0.999
cnr1_human	146	12.49x49	ICL1	S => R	missense	8.284e-06	1	120708	0	0.68	0.724
cnr1_human	145	12.48x48	ICL1	R => H	missense	4.143e-05	5	120674	0	0.43	0.185
cnr1_human	145	12.48x48	ICL1	R => S	missense	8.281e-06	1	120752	0	0.75	0.884
cnr1_human	140	1.56x56	TM1	V => I	missense	8.268e-06	1	120944	0	0.1	0.62
cnr1_human	133	1.49x49	TM1	E => G	missense	8.259e-06	1	121086	0	0.01	0.999
cnr1_human	120	1.36x36	TM1	A => S	missense	8.246e-06	1	121270	0	0.06	0.802
cnr1_human	113	1.29x29	TM1	P => S	missense	8.243e-06	1	121316	0	0.41	0.46
cnr1_human	97		N-term	Q => R	missense	4.12e-05	5	121364	0	0.12	0.209
cnr1_human	93		N-term	E => K	missense	0.0001566	19	121358	0	0.62	0.046
cnr1_human	87		N-term	S => L	missense	5.768e-05	7	121358	0	nan	0.058
cnr1_human	78		N-term	I => T	missense	8.241e-06	1	121338	0	nan	0.013
cnr1_human	78		N-term	I => V	missense	8.241e-06	1	121342	0	nan	0.001
cnr1_human	76		N-term	V => L	missense	8.241e-06	1	121344	0	nan	0.0
cnr1_human	75		N-term	Q => E	missense	1.648e-05	2	121340	0	nan	0.013
cnr1_human	74		N-term	D => G	missense	1.648e-05	2	121344	0	nan	0.031
cnr1_human	73		N-term	A => P	missense	8.241e-06	1	121340	0	nan	0.054
cnr1_human	67		N-term	N => S	missense	1.648e-05	2	121344	0	nan	0.0
cnr1_human	64		N-term	A => V	missense	4.121e-05	5	121338	0	nan	0.021
cnr1_human	63		N-term	T => P	missense	8.24e-06	1	121354	0	nan	0.004
cnr1_human	62		N-term	M => T	missense	8.24e-06	1	121354	0	nan	0.051
cnr1_human	59		N-term	Q => R	missense	8.24e-06	1	121360	0	nan	0.001
cnr1_human	59		N-term	Q => E	missense	8.24e-06	1	121356	0	nan	0.014
cnr1_human	55		N-term	G => A	missense	9.888e-05	12	121358	0	nan	0.118
cnr1_human	55		N-term	G => R	missense	8.24e-06	1	121358	0	nan	0.015
cnr1_human	43		N-term	Y => C	missense	8.237e-06	1	121402	0	0.02	0.628
cnr1_human	37		N-term	M => I	missense	8.237e-06	1	121404	0	nan	0.0
cnr1_human	34		N-term	K => R	missense	0.0001483	18	121404	0	nan	0.908
cnr1_human	31		N-term	E => K	missense	1.647e-05	2	121398	0	nan	0.122
cnr1_human	30		N-term	Y => H	missense	8.238e-06	1	121394	0	nan	0.996
cnr1_human	27		N-term	D => G	missense	7.414e-05	9	121388	0	nan	0.523
cnr1_human	26		N-term	N => S	missense	8.238e-06	1	121384	0	nan	0.971
cnr1_human	23		N-term	V => M	missense	0.0001401	17	121330	0	nan	0.002
cnr1_human	15		N-term	T => S	missense	8.288e-06	1	120650	0	0.0	0.987	PTM (Phosphorylation)
cnr1_human	14		N-term	R => H	missense	5.808e-05	7	120532	0	0.0	0.996
cnr1_human	14		N-term	R => C	missense	8.299e-06	1	120494	0	0.0	0.997
cnr1_human	13		N-term	F => V	missense	1.662e-05	2	120346	0	0.0	0.986
cnr1_human	7		N-term	G => D	missense	8.447e-05	10	118388	0	0.0	1.0
cnr1_human	4		N-term	I => N	missense	8.53e-06	1	117240	0	nan	0.518
cnr1_human	3		N-term	S => L	missense	2.567e-05	3	116890	0	0.0	0.99

Residue

deleterious missense variants are shown in red
tolerated missense variants are shown in green
loss of function mutations ('stop gained' or 'frameshift' in the coding region) are shown in blue

Diagrams

SnakePlot Download: PNG | SVG
HelixBox Download: PNG | SVG

Versions

Package	Name	Version
Django		2.2.1
Python		3.6.7
debug_toolbar	Debug Toolbar	1.11
polymorphic	Polymorphic	2.0.3
rest_framework	Django REST framework	3.9.3
rest_framework_swagger	Rest_Framework_Swagger	2.2.0

Time

Resource usage

Resource	Value
User CPU time	149.429 msec
System CPU time	3.890 msec
Total CPU time	153.319 msec
Elapsed time	164.138 msec
Context switches	10 voluntary, 3 involuntary

Browser timing

Timing attribute	Timeline	Milliseconds since navigation start (+length)

Settings from `protwis.settings`

Setting	Value
ABSOLUTE_URL_OVERRIDES	`{}`
ADMINS	`[]`
ALLOWED_HOSTS	`['*']`
APPEND_SLASH	`True`
AUTHENTICATION_BACKENDS	`['django.contrib.auth.backends.ModelBackend']`
AUTH_PASSWORD_VALIDATORS	`'********************'`
AUTH_USER_MODEL	`'auth.User'`
BASE_DIR	`'/home/protwis/gpcrdb_test'`
BUILD_CACHE_DIR	`'/home/protwis/gpcrdb_data/cache'`
CACHES	`{'alignments': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test_alignment', 'OPTIONS': {'MAX_ENTRIES': 1000}}, 'default': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test/', 'OPTIONS': {'MAX_ENTRIES': 10000000}}}`
CACHE_MIDDLEWARE_ALIAS	`'default'`
CACHE_MIDDLEWARE_KEY_PREFIX	`'********************'`
CACHE_MIDDLEWARE_SECONDS	`600`
CSRF_COOKIE_AGE	`31449600`
CSRF_COOKIE_DOMAIN	`None`
CSRF_COOKIE_HTTPONLY	`False`
CSRF_COOKIE_NAME	`'csrftoken'`
CSRF_COOKIE_PATH	`'/'`
CSRF_COOKIE_SAMESITE	`'Lax'`
CSRF_COOKIE_SECURE	`False`
CSRF_FAILURE_VIEW	`'django.views.csrf.csrf_failure'`
CSRF_HEADER_NAME	`'HTTP_X_CSRFTOKEN'`
CSRF_TRUSTED_ORIGINS	`[]`
CSRF_USE_SESSIONS	`False`
DATABASES	`{'default': {'ATOMIC_REQUESTS': False, 'AUTOCOMMIT': True, 'CONN_MAX_AGE': 0, 'ENGINE': 'django.db.backends.postgresql_psycopg2', 'HOST': 'localhost', 'NAME': 'protwis_202107', 'OPTIONS': {}, 'PASSWORD': '********************', 'PORT': '', 'TEST': {'CHARSET': None, 'COLLATION': None, 'MIRROR': None, 'NAME': None}, 'TIME_ZONE': None, 'USER': 'protwis'}}`
DATABASE_ROUTERS	`[]`
DATA_DIR	`'/home/protwis/gpcrdb_data'`
DATA_UPLOAD_MAX_MEMORY_SIZE	`2621440`
DATA_UPLOAD_MAX_NUMBER_FIELDS	`1000`
DATETIME_FORMAT	`'N j, Y, P'`
DATETIME_INPUT_FORMATS	`['%Y-%m-%d %H:%M:%S', '%Y-%m-%d %H:%M:%S.%f', '%Y-%m-%d %H:%M', '%Y-%m-%d', '%m/%d/%Y %H:%M:%S', '%m/%d/%Y %H:%M:%S.%f', '%m/%d/%Y %H:%M', '%m/%d/%Y', '%m/%d/%y %H:%M:%S', '%m/%d/%y %H:%M:%S.%f', '%m/%d/%y %H:%M', '%m/%d/%y']`
DATE_FORMAT	`'N j, Y'`
DATE_INPUT_FORMATS	`['%Y-%m-%d', '%m/%d/%Y', '%m/%d/%y', '%b %d %Y', '%b %d, %Y', '%d %b %Y', '%d %b, %Y', '%B %d %Y', '%B %d, %Y', '%d %B %Y', '%d %B, %Y']`
DEBUG	`True`
DEBUG_PROPAGATE_EXCEPTIONS	`False`
DEBUG_TOOLBAR_PATCH_SETTINGS	`False`
DECIMAL_SEPARATOR	`'.'`
DEFAULT_CHARSET	`'utf-8'`
DEFAULT_CONTENT_TYPE	`'text/html'`
DEFAULT_EXCEPTION_REPORTER_FILTER	`'django.views.debug.SafeExceptionReporterFilter'`
DEFAULT_FILE_STORAGE	`'django.core.files.storage.FileSystemStorage'`
DEFAULT_FROM_EMAIL	`'webmaster@localhost'`
DEFAULT_INDEX_TABLESPACE	`''`
DEFAULT_NUMBERING_SCHEME	`'gpcrdb'`
DEFAULT_PROTEIN_STATE	`'inactive'`
DEFAULT_SITE	`'gpcr'`
DEFAULT_TABLESPACE	`''`
DISALLOWED_USER_AGENTS	`[]`
DOCUMENTATION_URL	`'https://docs.gpcrdb.org/'`
EMAIL_BACKEND	`'django.core.mail.backends.smtp.EmailBackend'`
EMAIL_HOST	`'localhost'`
EMAIL_HOST_PASSWORD	`'********************'`
EMAIL_HOST_USER	`''`
EMAIL_PORT	`25`
EMAIL_SSL_CERTFILE	`None`
EMAIL_SSL_KEYFILE	`'********************'`
EMAIL_SUBJECT_PREFIX	`'[Django] '`
EMAIL_TIMEOUT	`None`
EMAIL_USE_LOCALTIME	`False`
EMAIL_USE_SSL	`False`
EMAIL_USE_TLS	`False`
FILE_CHARSET	`'utf-8'`
FILE_UPLOAD_DIRECTORY_PERMISSIONS	`None`
FILE_UPLOAD_HANDLERS	`['django.core.files.uploadhandler.MemoryFileUploadHandler', 'django.core.files.uploadhandler.TemporaryFileUploadHandler']`
FILE_UPLOAD_MAX_MEMORY_SIZE	`2621440`
FILE_UPLOAD_PERMISSIONS	`None`
FILE_UPLOAD_TEMP_DIR	`None`
FIRST_DAY_OF_WEEK	`0`
FIXTURE_DIRS	`[]`
FORCE_SCRIPT_NAME	`None`
FORMAT_MODULE_PATH	`None`
FORM_RENDERER	`'django.forms.renderers.DjangoTemplates'`
GOOGLE_ANALYTICS_API	`'********************'`
GOOGLE_ANALYTICS_KEY	`'********************'`
IGNORABLE_404_URLS	`[]`
INSTALLED_APPS	('django.contrib.admin', 'django.contrib.auth', 'django.contrib.contenttypes', 'django.contrib.sessions', 'django.contrib.messages', 'django.contrib.staticfiles', 'django.contrib.humanize', 'debug_toolbar', 'rest_framework', 'rest_framework_swagger', 'polymorphic', 'common', 'api', 'news', 'pages', 'home', 'protein', 'family', 'residue', 'alignment', 'similaritysearch', 'similaritymatrix', 'structure', 'ligand', 'interaction', 'mutation', 'phylogenetic_trees', 'sitesearch', 'build_gpcr', 'construct', 'tools', 'drugs', 'signprot', 'signprot2', 'mutational_landscape', 'contactnetwork', 'seqsign', 'angles', 'hotspots')
INTERNAL_IPS	`'10.0.2.2'`
LANGUAGES	[('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')]
LANGUAGES_BIDI	`['he', 'ar', 'fa', 'ur']`
LANGUAGE_CODE	`'en-us'`
LANGUAGE_COOKIE_AGE	`None`
LANGUAGE_COOKIE_DOMAIN	`None`
LANGUAGE_COOKIE_NAME	`'django_language'`
LANGUAGE_COOKIE_PATH	`'/'`
LOCALE_PATHS	`[]`
LOGGING	{'disable_existing_loggers': False, 'formatters': {'verbose': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s] %(message)s'}, 'verbose_low': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s]'}}, 'handlers': {'build': {'class': 'logging.FileHandler', 'filename': 'logs/build.log', 'formatter': 'verbose', 'level': 'DEBUG'}, 'django': {'class': 'logging.FileHandler', 'filename': 'logs/django.log', 'formatter': 'verbose', 'level': 'WARNING'}, 'protwis': {'class': 'logging.FileHandler', 'filename': 'logs/protwis.log', 'formatter': 'verbose', 'level': 'DEBUG'}}, 'loggers': {'build': {'handlers': ['build'], 'level': 'DEBUG'}, 'django': {'handlers': ['django'], 'level': 'WARNING', 'propagate': True}, 'protwis': {'handlers': ['protwis'], 'level': 'DEBUG'}}, 'version': 1}
LOGGING_CONFIG	`'logging.config.dictConfig'`
LOGIN_REDIRECT_URL	`'/accounts/profile/'`
LOGIN_URL	`'/accounts/login/'`
LOGOUT_REDIRECT_URL	`None`
MANAGERS	`[]`
MEDIA_ROOT	`'/protwis/media/protwis'`
MEDIA_URL	`'/media/'`
MESSAGE_STORAGE	`'django.contrib.messages.storage.fallback.FallbackStorage'`
MIDDLEWARE	`('common.middleware.stats.StatsMiddleware', 'debug_toolbar.middleware.DebugToolbarMiddleware', 'django.contrib.sessions.middleware.SessionMiddleware', 'django.middleware.common.CommonMiddleware', 'django.middleware.csrf.CsrfViewMiddleware', 'django.contrib.auth.middleware.AuthenticationMiddleware', 'django.contrib.messages.middleware.MessageMiddleware', 'django.middleware.clickjacking.XFrameOptionsMiddleware')`
MIGRATION_MODULES	`{}`
MONTH_DAY_FORMAT	`'F j'`
NUMBER_GROUPING	`0`
PASSWORD_HASHERS	`'********************'`
PASSWORD_RESET_TIMEOUT_DAYS	`'********************'`
PREPEND_WWW	`False`
REFERENCE_POSITIONS	`{'D1S1': 'D1S1x50', 'D1S2': 'D1S2x50', 'D1T1': 'D1T1x50', 'D1e1': 'D1e1x50', 'ECL1': '23x50', 'ECL2': '45x50', 'H8': '8x50', 'ICL1': '12x50', 'ICL2': '34x50', 'TM1': '1x50', 'TM2': '2x50', 'TM3': '3x50', 'TM4': '4x50', 'TM5': '5x50', 'TM6': '6x50', 'TM7': '7x50'}`
ROOT_URLCONF	`'protwis.urls'`
SECRET_KEY	`'********************'`
SECURE_BROWSER_XSS_FILTER	`False`
SECURE_CONTENT_TYPE_NOSNIFF	`False`
SECURE_HSTS_INCLUDE_SUBDOMAINS	`False`
SECURE_HSTS_PRELOAD	`False`
SECURE_HSTS_SECONDS	`0`
SECURE_PROXY_SSL_HEADER	`None`
SECURE_REDIRECT_EXEMPT	`[]`
SECURE_SSL_HOST	`None`
SECURE_SSL_REDIRECT	`False`
SERVER_EMAIL	`'root@localhost'`
SESSION_CACHE_ALIAS	`'default'`
SESSION_COOKIE_AGE	`86400`
SESSION_COOKIE_DOMAIN	`None`
SESSION_COOKIE_HTTPONLY	`True`
SESSION_COOKIE_NAME	`'sessionid'`
SESSION_COOKIE_PATH	`'/'`
SESSION_COOKIE_SAMESITE	`'Lax'`
SESSION_COOKIE_SECURE	`False`
SESSION_ENGINE	`'django.contrib.sessions.backends.db'`
SESSION_EXPIRE_AT_BROWSER_CLOSE	`False`
SESSION_FILE_PATH	`None`
SESSION_SAVE_EVERY_REQUEST	`False`
SESSION_SERIALIZER	`'django.contrib.sessions.serializers.PickleSerializer'`
SETTINGS_MODULE	`'protwis.settings'`
SHORT_DATETIME_FORMAT	`'m/d/Y P'`
SHORT_DATE_FORMAT	`'m/d/Y'`
SIGNING_BACKEND	`'django.core.signing.TimestampSigner'`
SILENCED_SYSTEM_CHECKS	`[]`
SITE_NAME	`'gpcr'`
SITE_TITLE	`'GPCRdb'`
STATICFILES_DIRS	`('/home/protwis/gpcrdb_test/static',)`
STATICFILES_FINDERS	`['django.contrib.staticfiles.finders.FileSystemFinder', 'django.contrib.staticfiles.finders.AppDirectoriesFinder']`
STATICFILES_STORAGE	`'django.contrib.staticfiles.storage.StaticFilesStorage'`
STATIC_ROOT	`'/home/protwis/static_test/'`
STATIC_URL	`'/static/'`
SWAGGER_SETTINGS	`{'USE_SESSION_AUTH': False}`
TEMPLATES	[{'APP_DIRS': True, 'BACKEND': 'django.template.backends.django.DjangoTemplates', 'DIRS': [], 'OPTIONS': {'context_processors': ['django.contrib.auth.context_processors.auth', 'django.template.context_processors.debug', 'django.template.context_processors.i18n', 'django.template.context_processors.media', 'django.template.context_processors.static', 'django.template.context_processors.tz', 'django.contrib.messages.context_processors.messages', 'protwis.context_processors.current_site', 'protwis.context_processors.canonical_tag', 'protwis.context_processors.documentation_url', 'protwis.context_processors.google_analytics', 'protwis.context_processors.site_title'], 'debug': True}}]
TEST_NON_SERIALIZED_APPS	`[]`
TEST_RUNNER	`'django.test.runner.DiscoverRunner'`
THOUSAND_SEPARATOR	`','`
TIME_FORMAT	`'P'`
TIME_INPUT_FORMATS	`['%H:%M:%S', '%H:%M:%S.%f', '%H:%M']`
TIME_ZONE	`'Europe/Copenhagen'`
USE_I18N	`True`
USE_L10N	`True`
USE_THOUSAND_SEPARATOR	`False`
USE_TZ	`True`
USE_X_FORWARDED_HOST	`False`
USE_X_FORWARDED_PORT	`False`
WSGI_APPLICATION	`None`
X_FRAME_OPTIONS	`'SAMEORIGIN'`
YEAR_MONTH_FORMAT	`'F Y'`

Headers

Request headers

Key	Value
Accept	text/html,application/xhtml+xml,application/xml;q=0.9,/;q=0.8
Accept-Encoding	br,gzip
Accept-Language	en-US,en;q=0.5
Connection	close
Host	test.gpcrdb.org
User-Agent	CCBot/2.0 (https://commoncrawl.org/faq/)
X-Forwarded-For	3.236.207.90
X-Forwarded-Proto	https
X-Real-Ip	3.236.207.90

Response headers

Key	Value
Content-Length	538901
Content-Type	text/html; charset=utf-8
Vary	Cookie
X-Frame-Options	SAMEORIGIN

WSGI environ

Since the WSGI environ inherits the environment of the server, only a significant subset is shown below.

Key	Value
PATH_INFO	/mutational_landscape/protein/CNR1_human/
QUERY_STRING
REMOTE_ADDR
REQUEST_METHOD	GET
SCRIPT_NAME
SERVER_NAME	test.gpcrdb.org
SERVER_PORT	443
SERVER_PROTOCOL	HTTP/1.0
SERVER_SOFTWARE	gunicorn/19.9.0

Request

View information

View function	Arguments	Keyword arguments	URL name
`mutational_landscape.views.render_variants`	`()`	`{'protein': 'CNR1_human'}`	`render`

No cookies

No session data

No GET data

No POST data

SQL queries from 1 connection

default 3.68 ms (1 query )

	Query	Timeline	Time (ms)	Action
	+	SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 'cnr1_human'	100.0%	3.68
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89) proteins.append(Protein.objects.get(entry_name=protein.lower()))

Query

Timeline

Time (ms)

Action

SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 'cnr1_human'

100.0%

3.68

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89)
  proteins.append(Protein.objects.get(entry_name=protein.lower()))

Static files (590 found, 40 used)

Static file path

/home/protwis/gpcrdb_test/static

Static file apps

django.contrib.admin
debug_toolbar
rest_framework
rest_framework_swagger
polymorphic

Static files

bootstrap/css/bootstrap.min.css: /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-submenu.min.css: /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
home/css/jquery-ui.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery-ui.min.css
home/css/jquery-ui.theme.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery-ui.theme.min.css
home/css/bootstrap-treeview.min.css: /home/protwis/gpcrdb_test/static/home/css/bootstrap-treeview.min.css
home/css/style.css: /home/protwis/gpcrdb_test/static/home/css/style.css
flowplayer/flowplayer.css: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
home/css/cookieconsent.min.css: /home/protwis/gpcrdb_test/static/home/css/cookieconsent.min.css
home/css/jquery.dataTables.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery.dataTables.min.css
home/css/structure_browser.css: /home/protwis/gpcrdb_test/static/home/css/structure_browser.css
home/css/residue_table.css: /home/protwis/gpcrdb_test/static/home/css/residue_table.css
home/css/alignment.css: /home/protwis/gpcrdb_test/static/home/css/alignment.css
: /home/protwis/gpcrdb_test/static
home/css/mainmenu.css: /home/protwis/gpcrdb_test/static/home/css/mainmenu.css
home/css/modal.css: /home/protwis/gpcrdb_test/static/home/css/modal.css
home/css/jquery.powertip.css: /home/protwis/gpcrdb_test/static/home/css/jquery.powertip.css
home/js/jquery-3.1.1.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/citation_tool.js: /home/protwis/gpcrdb_test/static/home/js/citation_tool.js
home/js/joinus_tool.js: /home/protwis/gpcrdb_test/static/home/js/joinus_tool.js
home/js/jquery-3.1.1.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/jquery-ui.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-ui.min.js
bootstrap/js/bootstrap.min.js: /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/js/bootstrap-submenu.js: /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
home/js/navbar-autocomplete.js: /home/protwis/gpcrdb_test/static/home/js/navbar-autocomplete.js
home/js/svg-pan-zoom.min.js: /home/protwis/gpcrdb_test/static/home/js/svg-pan-zoom.min.js
home/js/bootstrap-treeview.min.js: /home/protwis/gpcrdb_test/static/home/js/bootstrap-treeview.min.js
home/js/papaparse.min.js: /home/protwis/gpcrdb_test/static/home/js/papaparse.min.js
flowplayer/flowplayer.min.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.min.js
flowplayer/flowplayer.overlay.min.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.min.js
flowplayer/flowplayer.overlay.bootstrap.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.bootstrap.js
home/js/gpcrdb.js: /home/protwis/gpcrdb_test/static/home/js/gpcrdb.js
home/js/cookieconsent.min.js: /home/protwis/gpcrdb_test/static/home/js/cookieconsent.min.js
home/js/jquery.dataTables.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.min.js
home/js/dataTables.tableTools.min.js: /home/protwis/gpcrdb_test/static/home/js/dataTables.tableTools.min.js
home/js/jquery.dataTables.columnFilter.js: /home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.columnFilter.js
home/js/selection.js: /home/protwis/gpcrdb_test/static/home/js/selection.js
home/js/saveSvgAsPng.js: /home/protwis/gpcrdb_test/static/home/js/saveSvgAsPng.js
home/js/alignment.js: /home/protwis/gpcrdb_test/static/home/js/alignment.js
home/js/diagrams.js: /home/protwis/gpcrdb_test/static/home/js/diagrams.js
home/js/residuetable.js: /home/protwis/gpcrdb_test/static/home/js/residuetable.js

django.contrib.staticfiles.finders.FileSystemFinder (415 files)

Path	Location
visualization_scripts/maestro_label_generic_numbers.py	/home/protwis/gpcrdb_test/static/visualization_scripts/maestro_label_generic_numbers.py
visualization_scripts/pymol_view_generic_numbers.pml	/home/protwis/gpcrdb_test/static/visualization_scripts/pymol_view_generic_numbers.pml
bootstrap/js/npm.js	/home/protwis/gpcrdb_test/static/bootstrap/js/npm.js
bootstrap/js/bootstrap.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.js
bootstrap/js/bootstrap-submenu.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
bootstrap/js/bootstrap.min.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/fonts/glyphicons-halflings-regular.eot	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.eot
bootstrap/fonts/glyphicons-halflings-regular.woff	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff
bootstrap/fonts/glyphicons-halflings-regular.ttf	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.ttf
bootstrap/fonts/glyphicons-halflings-regular.svg	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.svg
bootstrap/fonts/glyphicons-halflings-regular.woff2	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff2
bootstrap/css/bootstrap.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css.map
bootstrap/css/bootstrap-submenu.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css
bootstrap/css/bootstrap.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css
bootstrap/css/bootstrap-theme.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css.map
bootstrap/css/bootstrap-theme.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css.map
bootstrap/css/bootstrap-submenu.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
bootstrap/css/bootstrap.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css.map
bootstrap/css/bootstrap-submenu.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css.map
bootstrap/css/bootstrap.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-theme.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css
bootstrap/css/bootstrap-theme.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css
blast/protwis_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psq
blast/protwis_human_bundle_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pin
blast/protwis_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pin
blast/protwis_human_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.phr
blast/protwis_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psd
blast/protwis_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.phr
blast/protwis_human_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psq
blast/protwis_human_gpcr_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.phr
blast/protwis_human_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psq
blast/protwis_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psd
blast/protwis_human_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pin
blast/protwis_human_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psd
blast/protwis_human_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pog
blast/.gitignore	/home/protwis/gpcrdb_test/static/blast/.gitignore
blast/protwis_human_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psd
blast/protwis_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pog
blast/protwis_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psq
blast/protwis_human_gpcr_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psi
blast/protwis_gpcr_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.pin
blast/protwis_human_bundle_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pog
blast/protwis_human_gpcr_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.pog
blast/protwis_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psi
blast/protwis_human_bundle_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.psd
blast/protwis_human_bundle_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.psq
blast/protwis_gpcr_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.pog
blast/protwis_human_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psi
blast/protwis_human_gpcr_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.pin
blast/protwis_gpcr_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psi
blast/protwis_gpcr_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.phr
blast/protwis_human_bundle_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.psi
blast/protwis_human_bundle_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.phr
flowplayer/flowplayer.min.js	/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.min.js
flowplayer/flowplayer.css	/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
flowplayer/flowplayer.overlay.min.js	/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.min.js
flowplayer/flowplayer.overlay.bootstrap.js	/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.bootstrap.js
flowplayer/fonts/fpicons.ttf	/home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.ttf
flowplayer/fonts/fpicons.woff	/home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.woff
flowplayer/fonts/fpicons.svg	/home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.svg
flowplayer/fonts/fpicons.eot	/home/protwis/gpcrdb_test/static/flowplayer/fonts/fpicons.eot
flowplayer/img/play_white.png	/home/protwis/gpcrdb_test/static/flowplayer/img/play_white.png
flowplayer/img/playful_white_rtl.png	/home/protwis/gpcrdb_test/static/flowplayer/img/playful_white_rtl.png
flowplayer/img/black_rtl@x2.png	/home/protwis/gpcrdb_test/static/flowplayer/img/black_rtl@x2.png
flowplayer/img/white.png	/home/protwis/gpcrdb_test/static/flowplayer/img/white.png
flowplayer/img/play_black_rtl.png	/home/protwis/gpcrdb_test/static/flowplayer/img/play_black_rtl.png
flowplayer/img/black_rtl.png	/home/protwis/gpcrdb_test/static/flowplayer/img/black_rtl.png
flowplayer/img/play_black.png	/home/protwis/gpcrdb_test/static/flowplayer/img/play_black.png
flowplayer/img/white_rtl.png	/home/protwis/gpcrdb_test/static/flowplayer/img/white_rtl.png
flowplayer/img/playful_white_rtl@x2.png	/home/protwis/gpcrdb_test/static/flowplayer/img/playful_white_rtl@x2.png
flowplayer/img/white_rtl@x2.png	/home/protwis/gpcrdb_test/static/flowplayer/img/white_rtl@x2.png
flowplayer/img/white@x2.png	/home/protwis/gpcrdb_test/static/flowplayer/img/white@x2.png
flowplayer/img/flowplayer@2x.png	/home/protwis/gpcrdb_test/static/flowplayer/img/flowplayer@2x.png
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home/css/select.dataTables.min.css	/home/protwis/gpcrdb_test/static/home/css/select.dataTables.min.css
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django.contrib.staticfiles.finders.AppDirectoriesFinder (175 files)

Templates (9 rendered)

Template paths

None

Templates

browser.html: /home/protwis/gpcrdb_test/mutational_landscape/templates/browser.html; Toggle context
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121358, 0, "missense", ' '"tolerated", "#70c070", ""], "87": ["L", 5.768e-05, 7, ' '121358, 0, "missense", "tolerated", "#70c070", ""], ' '"78": ["V", 8.241e-06, 1, 121342, 0, "missense", ' '"tolerated", "#70c070", ""], "76": ["L", 8.241e-06, 1, ' '121344, 0, "missense", "tolerated", "#70c070", ""], ' '"75": ["E", 1.648e-05, 2, 121340, 0, "missense", ' '"tolerated", "#70c070", ""], "74": ["G", 1.648e-05, 2, ' '121344, 0, "missense", "tolerated", "#70c070", ""], ' '"73": ["P", 8.241e-06, 1, 121340, 0, "missense", ' '"tolerated", "#70c070", ""], "67": ["S", 1.648e-05, 2, ' '121344, 0, "missense", "tolerated", "#70c070", ""], ' '"64": ["V", 4.121e-05, 5, 121338, 0, "missense", ' '"tolerated", "#70c070", ""], "63": ["P", 8.24e-06, 1, ' '121354, 0, "missense", "tolerated", "#70c070", ""], ' '"62": ["T", 8.24e-06, 1, 121354, 0, "missense", ' '"tolerated", "#70c070", ""], "59": ["E", 8.24e-06, 1, ' '121356, 0, "missense", "tolerated", "#70c070", ""], ' '"55": ["R", 8.24e-06, 1, 121358, 0, "missense", ' '"tolerated", "#70c070", ""], "43": ["C", 8.237e-06, 1, ' '121402, 0, "missense", "deleterious", "#e30e0e", ""], ' '"37": ["I", 8.237e-06, 1, 121404, 0, "missense", ' '"tolerated", "#70c070", ""], "34": ["R", 0.0001483, ' '18, 121404, 0, "missense", "deleterious", "#e30e0e", ' '""], "31": ["K", 1.647e-05, 2, 121398, 0, "missense", ' '"deleterious", "#e30e0e", ""], "30": ["H", 8.238e-06, ' '1, 121394, 0, "missense", "deleterious", "#e30e0e", ' '""], "27": ["G", 7.414e-05, 9, 121388, 0, "missense", ' '"deleterious", "#e30e0e", ""], "26": ["S", 8.238e-06, ' '1, 121384, 0, "missense", "deleterious", "#e30e0e", ' '""], "23": ["M", 0.0001401, 17, 121330, 0, "missense", ' '"tolerated", "#70c070", ""], "15": ["S", 8.288e-06, 1, ' '120650, 0, "missense", "deleterious", "#e30e0e", "PTM ' '(Phosphorylation) "], "14": ["C", 8.299e-06, 1, ' '120494, 0, "missense", "deleterious", "#e30e0e", ""], ' '"13": ["V", 1.662e-05, 2, 120346, 0, "missense", ' '"deleterious", "#e30e0e", ""], "7": ["D", 8.447e-05, ' '10, 118388, 0, "missense", "deleterious", "#e30e0e", ' '""], "4": ["N", 8.53e-06, 1, 117240, 0, "missense", ' '"deleterious", "#e30e0e", ""], "3": ["L", 2.567e-05, ' '3, 116890, 0, "missense", "deleterious", "#e30e0e", ' '""]}', 'natural_mutations_pos_list': '{"113": {"val": 1, "AA": "S "}, "120": {"val": ' '1, "AA": "S "}, "133": {"val": 1, "AA": "G "}, ' '"140": {"val": 1, "AA": "I "}, "145": {"val": ' '2, "AA": "H S "}, "146": {"val": 1, "AA": "R ' '"}, "151": {"val": 1, "AA": "A "}, "157": ' '{"val": 2, "AA": "S R "}, "160": {"val": 1, ' '"AA": "V "}, "164": {"val": 1, "AA": "F "}, ' '"168": {"val": 1, "AA": "A "}, "179": {"val": ' '1, "AA": "M "}, "185": {"val": 1, "AA": "N "}, ' '"186": {"val": 1, "AA": "L "}, "229": {"val": ' '1, "AA": "S "}, "231": {"val": 1, "AA": "T "}, ' '"234": {"val": 1, "AA": "M "}, "239": {"val": ' '1, "AA": "M "}, "243": {"val": 2, "AA": "M T ' '"}, "248": {"val": 1, "AA": "T "}, "249": ' '{"val": 1, "AA": "M "}, "274": {"val": 1, ' '"AA": "S "}, "285": {"val": 1, "AA": "I "}, ' '"291": {"val": 1, "AA": "L "}, "293": {"val": ' '1, "AA": "V "}, "299": {"val": 1, "AA": "R "}, ' '"305": {"val": 1, "AA": "T "}, "306": {"val": ' '1, "AA": "I "}, "307": {"val": 2, "AA": "H C ' '"}, "311": {"val": 2, "AA": "H C "}, "312": ' '{"val": 1, "AA": "D "}, "336": {"val": 1, ' '"AA": "C "}, "337": {"val": 1, "AA": "V "}, ' '"340": {"val": 1, "AA": "M "}, "351": {"val": ' '1, "AA": "L "}, "352": {"val": 1, "AA": "V "}, ' '"364": {"val": 1, "AA": "M "}, "405": {"val": ' '1, "AA": "Ter "}, "407": {"val": 1, "AA": "T ' '"}, "409": {"val": 2, "AA": "Q W "}, "410": ' '{"val": 1, "AA": "N "}, "412": {"val": 1, ' '"AA": "C "}, "color": ["#c79494", "#c40100"]}', 'receptor': 'cnr1_human', 'type': 'protein'} {'hosts': {'arrestin': '', 'gpcr': '', 'gprotein': ''}}

Context processors

django.template.context_processors.csrf: Toggle context
{'csrf_token': <SimpleLazyObject: '62YD0Y5Oaaw8oacbq9uD7HgYMU4HUFw4BMQyeNsFDTr5TL9RS5yunN4k8LqOMGCK'>}
django.contrib.auth.context_processors.auth: Toggle context
{'user': <SimpleLazyObject: <django.contrib.auth.models.AnonymousUser object at 0x7f2e72700630>>, 'perms': <django.contrib.auth.context_processors.PermWrapper object at 0x7f2e2f120128>}
django.template.context_processors.debug: Toggle context
{'debug': True, 'sql_queries': <function debug.<locals>.<lambda> at 0x7f2e6849d7b8>}
django.template.context_processors.i18n: Toggle context
{'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')], 'LANGUAGE_CODE': 'en-us', 'LANGUAGE_BIDI': False}
django.template.context_processors.media: Toggle context
{'MEDIA_URL': '/media/'}
django.template.context_processors.static: Toggle context
{'STATIC_URL': '/static/'}
django.template.context_processors.tz: Toggle context
{'TIME_ZONE': 'Europe/Copenhagen'}
django.contrib.messages.context_processors.messages: Toggle context
{'messages': <django.contrib.messages.storage.fallback.FallbackStorage object at 0x7f2e73d97c88>, 'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30, 'ERROR': 40}}
protwis.context_processors.current_site: Toggle context
{'current_site': 'gpcr'}
protwis.context_processors.canonical_tag: Toggle context
{'canonical_tag': 'https://gpcrdb.org/mutational_landscape/protein/CNR1_human/'}
protwis.context_processors.documentation_url: Toggle context
{'documentation_url': 'https://docs.gpcrdb.org/'}
protwis.context_processors.google_analytics: Toggle context
{}
protwis.context_processors.site_title: Toggle context
{'site_title': 'GPCRdb'}

Cache calls from 2 backends

Summary

Total calls	Total time	Cache hits	Cache misses
3	23.540496826171875 ms	2	0

Commands

add	get	set	delete	clear	get_many	set_many	delete_many	has_key	incr	decr	incr_version	decr_version
0	2	0	0	0	0	0	0	1	0	0	0	0

Calls

Time (ms)		Type	Arguments	Keyword arguments	Backend
+	1.2064	has_key	('VARIATION_529d3cd9590dcae55282882c7a04e779',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e2abed908>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(122) if not cache_variation.has_key(cache_key) and len(proteins)>0:
+	22.1636	get	('VARIATION_529d3cd9590dcae55282882c7a04e779',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e2abed908>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(252) cache_data = cache_variation.get(cache_key)
+	0.1705	get	('citation_urls',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e2abed908>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(292) return render(request, 'browser.html', cache_data) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/shortcuts.py in render(36) content = loader.render_to_string(template_name, context, request, using=using) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/loader.py in render_to_string(62) return template.render(context, request) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/backends/django.py in render(61) return self.template.render(context) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/base.py in render(169) with context.bind_template(self): /usr/lib/python3.6/contextlib.py in __enter__(81) return next(self.gen) /home/protwis/gpcrdb_test/protwis/context_processors.py in canonical_tag(31) citation_dict = cache.get("citation_urls")

Signals

Signal	Providing	Receivers
class_prepared	class
connection_created	connection
got_request_exception	request
post_delete	instance, using
post_init	instance
post_migrate	app_config, plan, interactive, verbosity, apps, using	create_permissions, create_contenttypes
post_save	created, raw, instance, update_fields, using
pre_delete	instance, using
pre_init	instance, args, kwargs
pre_save	instance, using, update_fields, raw
request_finished		close_old_connections, close_caches, reset_urlconf
request_started	environ	reset_queries, close_old_connections

Log messages

No messages logged.

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admin/js/cancel.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/cancel.js
admin/js/autocomplete.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/autocomplete.js
admin/js/collapse.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.min.js
admin/js/actions.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.min.js
admin/js/urlify.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/urlify.js
admin/js/popup_response.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/popup_response.js
admin/js/collapse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.js
admin/js/SelectBox.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectBox.js
admin/js/calendar.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/calendar.js
admin/js/actions.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.js
admin/js/prepopulate.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate.min.js
admin/js/SelectFilter2.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectFilter2.js
admin/js/timeparse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/timeparse.js
admin/js/jquery.init.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/jquery.init.js
admin/js/core.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/core.js
admin/js/prepopulate_init.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate_init.js
admin/js/inlines.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/inlines.js
admin/js/inlines.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/inlines.min.js
admin/js/change_form.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/change_form.js
admin/js/prepopulate.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate.js
admin/js/vendor/xregexp/xregexp.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/xregexp/xregexp.js
admin/js/vendor/xregexp/LICENSE.txt	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/xregexp/LICENSE.txt
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admin/js/vendor/jquery/jquery.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/jquery/jquery.min.js
admin/js/vendor/jquery/LICENSE.txt	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/jquery/LICENSE.txt
admin/js/vendor/jquery/jquery.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/jquery/jquery.js
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admin/js/vendor/select2/select2.full.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/select2.full.min.js
admin/js/vendor/select2/LICENSE.md	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/LICENSE.md
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admin/js/vendor/select2/i18n/zh-CN.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/zh-CN.js
admin/js/vendor/select2/i18n/fa.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/vendor/select2/i18n/fa.js

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