Variation Browser

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Receptor Position GPCRdb Segment Variant Mutation type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
Receptor Position GPCRdb Segment Variant Mutation Type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
fshr_human 647 C-term Y => Ter stop gained 8.242e-06 1 121334 0 None None
fshr_human 628 7.55x55 TM7 I => SerfsTer14 frameshift 8.241e-06 1 121338 0 None None GP (contact)
fshr_human 606 7.33x32 TM7 K => Ter stop gained 8.244e-06 1 121300 0 None None
fshr_human 570 6.33x33 TM6 I => AspfsTer12 frameshift 8.257e-06 1 121114 0 None None GP (contact)
fshr_human 553 5.62x62 TM5 Y => Ter stop gained 8.26e-06 1 121070 0 None None
fshr_human 505 4.61x61 TM4 I => SerfsTer8 frameshift 8.297e-06 1 120530 0 None None
fshr_human 494 4.50x50 TM4 W => Ter stop gained 1.661e-05 2 120392 0 None None
fshr_human 493 4.49x49 TM4 G => AlafsTer20 frameshift 1.661e-05 2 120390 0 None None
fshr_human 391 ICL1 Q => AsnfsTer70 frameshift 8.241e-06 1 121350 0 None None
fshr_human 349 N-term K => Ter stop gained 8.239e-06 1 121378 0 None None
fshr_human 282 N-term R => Ter stop gained 8.248e-06 1 121246 0 None None
fshr_human 176 N-term W => Ter stop gained 8.296e-06 1 120536 0 None None
fshr_human 170 N-term F => LeufsTer4 frameshift 8.335e-06 1 119976 0 None None
fshr_human 162 N-term R => Ter stop gained 8.396e-06 1 119100 0 None None
fshr_human 145 N-term Q => Ter stop gained 8.258e-06 1 121100 0 None None
fshr_human 133 N-term K => Ter frameshift 8.27e-06 1 120926 0 None None
fshr_human 64 N-term G => ValfsTer12 frameshift 8.256e-06 1 121120 0 None None
fshr_human 33 N-term Q => Ter stop gained 8.275e-06 1 120842 0 None None
fshr_human 2 N-term A => GlyfsTer frameshift 8.277e-06 1 120816 0 None None
fshr_human 690 C-term S => G missense 8.24e-06 1 121360 0 0.04 0.138
fshr_human 689 C-term L => Q missense 1.648e-05 2 121362 0 0.01 0.248
fshr_human 689 C-term L => P missense 8.24e-06 1 121362 0 0.01 0.951
fshr_human 685 C-term I => K missense 8.24e-06 1 121360 0 0.34 0.002
fshr_human 681 C-term G => S missense 1.648e-05 2 121358 0 0.08 0.027
fshr_human 679 C-term T => I missense 8.248e-06 1 121236 0 0.04 0.008
fshr_human 678 C-term V => D missense 8.239e-06 1 121372 0 0.51 0.139
fshr_human 677 C-term R => T missense 1.648e-05 2 121376 0 0.05 0.062
fshr_human 677 C-term R => K missense 8.239e-06 1 121376 0 1.0 0.003
fshr_human 676 C-term P => S missense 8.239e-06 1 121370 0 0.32 0.005
fshr_human 675 C-term A => G missense 1.648e-05 2 121370 0 0.43 0.011
fshr_human 671 C-term H => Q missense 8.239e-06 1 121368 0 0.27 0.098
fshr_human 671 C-term H => Y missense 1.648e-05 2 121362 0 0.68 0.761
fshr_human 667 C-term P => A missense 8.24e-06 1 121358 0 0.53 0.001
fshr_human 663 C-term H => Q missense 5.768e-05 7 121350 0 0.04 0.968
fshr_human 658 C-term T => I missense 8.241e-06 1 121342 0 0.1 0.029
fshr_human 657 C-term E => D missense 8.241e-06 1 121340 0 0.07 0.106
fshr_human 655 C-term R => T missense 8.242e-06 1 121334 0 0.0 0.739
fshr_human 653 C-term I => S missense 8.241e-06 1 121346 0 0.06 0.037
fshr_human 649 C-term M => I missense 8.242e-06 1 121324 0 0.32 0.003
fshr_human 645 8.62x62 H8 G => C missense 8.243e-06 1 121310 0 0.0 1.0
fshr_human 642 8.59x59 H8 S => T missense 8.242e-06 1 121328 0 0.0 0.678
fshr_human 636 8.53x53 H8 D => A missense 8.242e-06 1 121332 0 0.0 0.998
fshr_human 634 8.51x51 H8 R => H missense 4.121e-05 5 121318 0 0.0 0.881 GP (contact)
fshr_human 634 8.51x51 H8 R => C missense 2.473e-05 3 121332 0 0.0 0.999 GP (contact)
fshr_human 630 8.47x47 H8 T => A missense 1.648e-05 2 121328 0 0.0 0.996 GP (contact)
fshr_human 629 7.56x56 TM7 F => I missense 7.418e-05 9 121330 0 0.0 0.939 GP (contact)
fshr_human 628 7.55x55 TM7 I => T missense 8.241e-06 1 121338 0 0.0 0.847 GP (contact)
fshr_human 626 7.53x53 TM7 Y => C missense 8.241e-06 1 121340 0 0.0 1.0 SodiumPocket MicroSwitch
fshr_human 625 7.52x52 TM7 L => F missense 8.241e-06 1 121338 0 0.0 0.999
fshr_human 624 7.51x51 TM7 F => L missense 1.648e-05 2 121346 0 0.0 0.973
fshr_human 611 7.38x37 TM7 L => P missense 8.243e-06 1 121316 0 0.0 0.999 LB (polar (hydrogen bond with backbone), Van der Waals)
fshr_human 604 7.31x30 TM7 V => M missense 1.649e-05 2 121286 0 0.0 0.999 LB (Van der Waals)
fshr_human 600 ECL3 P => S missense 8.248e-06 1 121248 0 0.0 0.863
fshr_human 599 ECL3 V => L missense 8.249e-06 1 121230 0 0.34 0.005
fshr_human 598 6.61x61 TM6 K => E missense 8.252e-06 1 121182 0 0.0 0.747
fshr_human 596 6.59x59 TM6 S => T missense 2.475e-05 3 121196 0 0.04 0.044 LB (polar (hydrogen bond))
fshr_human 593 6.56x56 TM6 I => V missense 2.477e-05 3 121122 0 0.0 0.45
fshr_human 590 6.53x53 TM6 F => S missense 8.256e-06 1 121122 0 0.0 0.935
fshr_human 583 6.46x46 TM6 L => F missense 1.651e-05 2 121128 0 0.01 0.388
fshr_human 581 6.44x44 TM6 D => E missense 8.258e-06 1 121100 0 0.0 0.987 SodiumPocket MicroSwitch
fshr_human 578 6.41x41 TM6 I => S missense 8.255e-06 1 121136 0 0.0 0.998
fshr_human 576 6.39x39 TM6 M => I missense 1.652e-05 2 121092 0 0.41 0.001
fshr_human 573 6.36x36 TM6 R => H missense 1.652e-05 2 121076 0 0.0 0.999 GP (contact)
fshr_human 573 6.36x36 TM6 R => C missense 2.478e-05 3 121088 0 0.0 1.0 GP (contact)
fshr_human 571 6.34x34 TM6 A => T missense 2.478e-05 3 121060 0 0.0 1.0 SodiumPocket MicroSwitch
fshr_human 569 6.32x32 TM6 R => T missense 1.652e-05 2 121094 0 0.01 0.03 GP (contact)
fshr_human 563 6.26x26 TM6 S => F missense 8.256e-06 1 121124 0 0.0 0.984 GP (contact)
fshr_human 562 ICL3 V => M missense 0.0001486 18 121100 0 0.36 0.033
fshr_human 560 ICL3 N => I missense 8.257e-06 1 121106 0 0.02 0.642
fshr_human 558 ICL3 N => H missense 1.652e-05 2 121072 0 0.03 0.967
fshr_human 557 5.66x66 TM5 R => Q missense 8.264e-05 10 121004 0 0.3 0.985 GP (contact)
fshr_human 557 5.66x66 TM5 R => W missense 8.263e-05 10 121022 0 0.0 0.999 GP (contact)
fshr_human 555 5.64x64 TM5 T => I missense 8.258e-06 1 121098 0 0.01 0.977 GP (contact)
fshr_human 553 5.62x62 TM5 Y => S missense 2.478e-05 3 121074 0 0.0 0.999
fshr_human 548 5.57x57 TM5 C => Y missense 8.259e-06 1 121076 0 0.0 0.996
fshr_human 547 5.56x56 TM5 G => S missense 8.26e-06 1 121066 0 0.19 0.014
fshr_human 545 5.54x54 TM5 I => T missense 8.258e-06 1 121096 0 0.0 0.997
fshr_human 536 5.45x45 TM5 V => L missense 8.258e-06 1 121092 0 0.7 0.018
fshr_human 535 5.44x44 TM5 L => H missense 8.258e-06 1 121098 0 0.0 1.0 LB (Van der Waals)
fshr_human 532 5.41x41 TM5 M => I missense 4.956e-05 6 121076 0 1.0 0.003
fshr_human 529 5.38x38 TM5 L => P missense 8.262e-06 1 121034 0 0.01 0.713
fshr_human 528 5.37x37 TM5 Q => R missense 1.653e-05 2 121018 0 0.02 0.952
fshr_human 528 5.37x37 TM5 Q => K missense 8.264e-06 1 121002 0 0.03 0.542
fshr_human 524 5.33x33 TM5 S => R missense 0.0003472 42 120958 0 0.01 0.481
fshr_human 524 5.33x33 TM5 S => R missense 2.48e-05 3 120958 0 0.01 0.481
fshr_human 523 ECL2 D => V missense 4.962e-05 6 120920 0 0.0 0.466
fshr_human 522 ECL2 I => T missense 8.269e-06 1 120936 0 0.53 0.255
fshr_human 520 ECL2 M => I missense 8.274e-06 1 120860 0 0.0 0.369
fshr_human 515 ECL2 S => N missense 1.656e-05 2 120738 0 0.0 0.944
fshr_human 508 ECL2 I => M missense 8.294e-06 1 120570 0 0.0 0.89
fshr_human 505 4.61x61 TM4 I => M missense 8.298e-06 1 120516 0 0.05 0.167
fshr_human 505 4.61x61 TM4 I => T missense 8.293e-06 1 120578 0 0.02 0.628
fshr_human 502 4.58x58 TM4 L => V missense 8.304e-06 1 120420 0 0.12 0.492
fshr_human 495 4.51x51 TM4 I => S missense 1.661e-05 2 120412 0 0.0 0.159
fshr_human 495 4.51x51 TM4 I => L missense 8.305e-06 1 120410 0 1.0 0.006
fshr_human 493 4.49x49 TM4 G => D missense 2.493e-05 3 120318 0 0.0 1.0
fshr_human 492 4.48x48 TM4 M => T missense 8.304e-06 1 120426 0 0.15 0.0
fshr_human 489 4.45x45 TM4 V => A missense 1.661e-05 2 120418 0 0.03 0.024
fshr_human 487 4.43x43 TM4 A => T missense 8.305e-06 1 120410 0 0.35 0.008
fshr_human 485 4.41x41 TM4 H => R missense 8.305e-06 1 120414 0 0.01 0.706
fshr_human 484 4.40x40 TM4 R => H missense 4.156e-05 5 120308 0 0.11 0.266
fshr_human 484 4.40x40 TM4 R => C missense 1.662e-05 2 120312 0 0.01 0.336
fshr_human 482 4.38x38 TM4 Q => H missense 8.307e-06 1 120384 0 0.08 0.006
fshr_human 481 34.57x57 ICL2 V => M missense 8.302e-06 1 120446 0 0.03 0.298 GP (contact)
fshr_human 477 34.53x53 ICL2 L => R missense 8.296e-06 1 120534 0 0.02 0.828 GP (contact)
fshr_human 472 3.55x55 TM3 T => M missense 8.29e-06 1 120624 0 0.0 0.995 GP (contact)
fshr_human 472 3.55x55 TM3 T => K missense 8.29e-06 1 120624 0 0.0 0.917 GP (contact)
fshr_human 468 3.51x51 TM3 W => L missense 8.28e-06 1 120772 0 0.0 0.961
fshr_human 461 3.44x44 TM3 T => I missense 8.265e-06 1 120988 0 0.01 0.262
fshr_human 461 3.44x44 TM3 T => K missense 8.265e-06 1 120988 0 0.0 0.87
fshr_human 449 3.32x32 TM3 T => N missense 8.252e-06 1 121184 0 0.0 0.981 LB (polar (hydrogen bond with backbone), Van der Waals)
fshr_human 448 3.31x31 TM3 F => L missense 8.25e-06 1 121208 0 0.26 0.015
fshr_human 446 3.29x29 TM3 G => S missense 8.25e-06 1 121210 0 0.0 0.995
fshr_human 444 3.27x27 TM3 A => T missense 0.0002392 29 121240 0 0.5 0.044
fshr_human 443 3.26x26 TM3 D => Y missense 1.649e-05 2 121262 0 0.01 0.315
fshr_human 440 3.23x23 TM3 A => T missense 8.245e-06 1 121284 0 0.04 0.253
fshr_human 438 ECL1 T => I missense 8.244e-06 1 121300 0 0.0 0.95
fshr_human 437 ECL1 Q => K missense 8.244e-06 1 121298 0 0.03 0.971
fshr_human 434 ECL1 I => V missense 8.243e-06 1 121314 0 0.0 0.953
fshr_human 427 ECL1 S => N missense 8.242e-06 1 121336 0 0.08 0.162
fshr_human 421 2.63x63 TM2 V => L missense 8.241e-06 1 121342 0 0.0 0.953
fshr_human 419 2.61x61 TM2 A => T missense 8.241e-06 1 121348 0 0.0 0.996
fshr_human 412 2.54x54 TM2 G => E missense 8.24e-06 1 121358 0 0.0 1.0
fshr_human 411 2.53x53 TM2 I => T missense 8.24e-06 1 121356 0 0.06 0.053
fshr_human 410 2.52x52 TM2 C => F missense 8.24e-06 1 121356 0 0.0 0.929
fshr_human 401 2.43x43 TM2 M => I missense 8.24e-06 1 121356 0 0.0 0.932
fshr_human 400 2.42x42 TM2 L => F missense 1.648e-05 2 121356 0 0.01 0.986
fshr_human 386 1.56x56 TM1 I => T missense 1.648e-05 2 121338 0 0.02 0.072
fshr_human 382 1.52x52 TM1 I => T missense 8.242e-06 1 121336 0 0.38 0.005
fshr_human 377 1.47x47 TM1 I => V missense 8.241e-06 1 121348 0 0.25 0.015
fshr_human 374 1.44x44 TM1 I => F missense 8.241e-06 1 121340 0 0.0 0.358
fshr_human 373 1.43x43 TM1 S => N missense 8.242e-06 1 121336 0 0.92 0.034
fshr_human 372 1.42x42 TM1 I => V missense 8.242e-06 1 121336 0 0.49 0.063
fshr_human 368 1.38x38 TM1 L => V missense 8.242e-06 1 121330 0 0.46 0.621
fshr_human 363 1.33x33 TM1 N => T missense 8.241e-06 1 121344 0 0.48 0.012
fshr_human 360 N-term M => T missense 1.648e-05 2 121350 0 0.0 0.8
fshr_human 350 N-term P => S missense 8.239e-06 1 121378 0 0.1 0.967
fshr_human 348 N-term P => R missense 8.238e-06 1 121384 0 0.0 0.993
fshr_human 344 N-term V => M missense 3.295e-05 4 121388 0 0.17 0.961
fshr_human 343 N-term D => E missense 8.238e-06 1 121382 0 0.59 0.009
fshr_human 342 N-term V => L missense 8.238e-06 1 121386 0 0.37 0.098
fshr_human 342 N-term V => I missense 8.238e-06 1 121386 0 0.24 0.008
fshr_human 341 N-term V => A missense 0.0004201 51 121388 0 0.75 0.012
fshr_human 339 N-term N => S missense 8.238e-06 1 121388 0 0.35 0.018
fshr_human 333 N-term F => L missense 8.238e-06 1 121392 0 0.13 0.012
fshr_human 331 N-term T => S missense 8.238e-06 1 121394 0 1.0 0.001
fshr_human 329 N-term T => M missense 1.648e-05 2 121396 0 0.41 0.005
fshr_human 327 N-term D => H missense 8.237e-06 1 121398 0 0.0 1.0
fshr_human 325 N-term G => R missense 8.238e-06 1 121394 0 0.04 0.037
fshr_human 319 N-term E => G missense 8.237e-05 10 121404 0 0.03 0.004
fshr_human 318 N-term N => S missense 3.295e-05 4 121402 0 0.16 0.016
fshr_human 317 N-term D => N missense 8.237e-06 1 121402 0 0.24 0.76
fshr_human 315 N-term A => T missense 8.238e-06 1 121394 0 nan 0.012
fshr_human 312 N-term S => F missense 8.238e-06 1 121396 0 nan 0.094
fshr_human 310 N-term Q => R missense 8.238e-06 1 121396 0 0.15 0.005
fshr_human 309 N-term G => D missense 1.648e-05 2 121394 0 0.36 0.007
fshr_human 309 N-term G => C missense 2.471e-05 3 121398 0 nan 0.754
fshr_human 308 N-term R => G missense 8.238e-06 1 121392 0 nan 0.003
fshr_human 307 N-term A => T missense 0.5446 66099 121368 18755 0.5 0.007
fshr_human 307 N-term A => P missense 8.239e-06 1 121368 0 0.23 0.009
fshr_human 305 N-term T => S missense 1.649e-05 2 121256 0 nan 0.197
fshr_human 303 N-term Y => D missense 8.252e-06 1 121186 0 nan 0.001
fshr_human 300 N-term E => Q missense 8.267e-06 1 120962 0 nan 0.724
fshr_human 298 N-term R => S missense 1.654e-05 2 120908 0 0.0 0.138
fshr_human 298 N-term R => K missense 1.654e-05 2 120888 0 0.31 0.003
fshr_human 294 N-term K => I missense 2.489e-05 3 120510 0 0.18 0.091
fshr_human 293 N-term N => S missense 8.299e-06 1 120496 0 0.06 0.651
fshr_human 292 N-term C => G missense 8.312e-06 1 120302 0 0.04 0.998
fshr_human 291 N-term I => M missense 8.312e-06 1 120306 0 0.19 0.546
fshr_human 283 N-term R => Q missense 9.075e-05 11 121214 0 0.06 0.087
fshr_human 283 N-term R => W missense 5.774e-05 7 121230 0 0.01 0.104
fshr_human 282 N-term R => K missense 8.248e-06 1 121238 0 1.0 0.011
fshr_human 279 N-term A => E missense 8.247e-06 1 121262 0 0.33 0.025
fshr_human 267 N-term A => T missense 8.247e-06 1 121254 0 0.03 0.945
fshr_human 263 N-term A => V missense 1.649e-05 2 121252 0 0.11 0.005
fshr_human 263 N-term A => T missense 8.248e-06 1 121248 0 0.23 0.003
fshr_human 261 N-term L => F missense 8.249e-06 1 121234 0 1.0 0.004
fshr_human 260 N-term K => N missense 8.248e-06 1 121238 0 0.26 0.001
fshr_human 259 N-term E => K missense 1.65e-05 2 121226 0 0.57 0.01
fshr_human 248 N-term S => L missense 2.478e-05 3 121088 0 0.01 0.02
fshr_human 247 N-term R => T missense 8.259e-06 1 121074 0 0.33 0.005
fshr_human 247 N-term R => K missense 8.259e-06 1 121074 0 0.28 0.001
fshr_human 243 N-term K => M missense 4.961e-05 6 120934 0 0.12 0.098
fshr_human 239 N-term E => K missense 8.28e-06 1 120780 0 0.06 0.012
fshr_human 236 N-term Y => C missense 4.974e-05 6 120616 0 0.16 0.013
fshr_human 235 N-term S => T missense 8.293e-06 1 120578 0 0.28 0.004
fshr_human 234 N-term P => R missense 8.308e-06 1 120372 0 0.0 1.0
fshr_human 230 N-term I => V missense 1.674e-05 2 119474 0 0.49 0.047
fshr_human 229 N-term R => G missense 3.353e-05 4 119288 0 0.29 0.001
fshr_human 228 N-term T => I missense 1.679e-05 2 119118 0 0.0 0.998 PTM (Phosphorylation)
fshr_human 227 N-term R => K missense 8.445e-06 1 118420 0 0.23 0.014
fshr_human 227 N-term R => G missense 8.445e-06 1 118410 0 0.23 0.001
fshr_human 222 N-term I => T missense 8.257e-06 1 121108 0 0.04 0.551
fshr_human 222 N-term I => V missense 2.477e-05 3 121110 0 0.83 0.004
fshr_human 218 N-term S => C missense 8.252e-06 1 121180 0 0.01 0.946 PTM (Phosphorylation)
fshr_human 217 N-term A => G missense 8.252e-06 1 121190 0 0.0 0.794
fshr_human 209 N-term L => V missense 8.245e-06 1 121286 0 0.04 0.609
fshr_human 204 N-term N => K missense 8.245e-06 1 121290 0 0.93 0.018
fshr_human 202 N-term D => N missense 8.245e-06 1 121290 0 0.22 0.088
fshr_human 202 N-term D => Y missense 8.245e-06 1 121290 0 0.01 0.41
fshr_human 201 N-term S => R missense 0.0001237 15 121298 0 0.23 1.0
fshr_human 201 N-term S => G missense 8.244e-06 1 121306 0 0.05 0.996
fshr_human 193 N-term T => I missense 8.244e-06 1 121298 0 0.0 0.997
fshr_human 192 N-term G => E missense 8.245e-06 1 121290 0 0.0 0.999
fshr_human 191 N-term N => S missense 0.0001319 16 121286 0 0.0 0.359 PTM (N-linked Glycosylation)
fshr_human 190 N-term F => L missense 8.246e-06 1 121274 0 0.01 0.999
fshr_human 189 N-term A => V missense 0.0006185 75 121268 0 0.0 0.978
fshr_human 187 N-term N => K missense 1.649e-05 2 121252 0 0.01 0.24
fshr_human 178 N-term N => H missense 8.279e-06 1 120792 0 0.12 0.864
fshr_human 173 N-term V => L missense 5.008e-05 6 119806 0 0.61 0.005
fshr_human 172 N-term S => N missense 8.344e-06 1 119846 0 0.09 0.012
fshr_human 170 N-term F => L missense 8.336e-06 1 119964 0 0.04 0.002
fshr_human 168 N-term L => M missense 2.501e-05 3 119934 0 0.57 0.997
fshr_human 166 N-term V => L missense 0.0002004 24 119764 1 0.75 0.0
fshr_human 163 N-term N => S missense 8.384e-06 1 119268 0 0.0 0.762
fshr_human 162 N-term R => K missense 0.004614 550 119192 5 0.66 0.003
fshr_human 162 N-term R => G missense 2.519e-05 3 119100 0 0.48 0.004
fshr_human 160 N-term I => T missense 2.53e-05 3 118564 0 0.0 0.826
fshr_human 159 N-term T => A missense 1.693e-05 2 118162 0 0.08 0.001
fshr_human 158 N-term H => Q missense 1.693e-05 2 118150 0 0.42 0.003
fshr_human 157 N-term I => V missense 8.519e-06 1 117388 0 0.01 0.206
fshr_human 152 N-term Q => P missense 8.803e-06 1 113598 0 0.14 0.999
fshr_human 149 N-term L => F missense 8.258e-06 1 121096 0 0.06 1.0
fshr_human 146 N-term K => T missense 8.258e-06 1 121100 0 0.14 0.026
fshr_human 138 N-term V => I missense 3.304e-05 4 121052 0 0.01 0.208
fshr_human 137 N-term D => E missense 8.262e-06 1 121040 0 0.03 0.098
fshr_human 137 N-term D => V missense 8.262e-06 1 121034 0 0.09 0.018
fshr_human 135 N-term L => F missense 8.266e-06 1 120978 0 0.3 0.233
fshr_human 135 N-term L => I missense 8.266e-06 1 120978 0 0.04 0.095
fshr_human 132 N-term I => T missense 1.654e-05 2 120916 0 0.0 0.998
fshr_human 123 N-term Q => E missense 9.941e-05 12 120718 0 0.0 0.028
fshr_human 121 N-term N => S missense 1.656e-05 2 120780 0 0.35 0.035
fshr_human 120 N-term P => L missense 8.279e-06 1 120792 0 0.0 1.0
fshr_human 119 N-term L => F missense 8.276e-06 1 120834 0 0.0 1.0
fshr_human 118 N-term N => K missense 2.483e-05 3 120838 0 0.0 0.445
fshr_human 113 N-term P => A missense 1.656e-05 2 120798 0 0.09 0.008
fshr_human 112 N-term N => H missense 8.279e-06 1 120790 0 0.23 0.944
fshr_human 111 N-term I => M missense 8.279e-06 1 120788 0 0.02 0.939
fshr_human 110 N-term Y => H missense 8.281e-06 1 120756 0 0.29 0.088
fshr_human 109 N-term L => V missense 3.314e-05 4 120698 0 0.86 0.033
fshr_human 102 N-term I => V missense 8.335e-06 1 119974 0 0.01 0.812
fshr_human 98 N-term H => L missense 8.239e-06 1 121378 0 0.25 0.608
fshr_human 96 N-term K => E missense 8.241e-06 1 121350 0 0.14 0.14
fshr_human 89 N-term D => Y missense 0.0001484 18 121254 0 0.12 0.046
fshr_human 86 N-term I => T missense 8.25e-06 1 121210 0 0.0 0.995
fshr_human 76 N-term E => D missense 1.655e-05 2 120844 0 0.05 0.973
fshr_human 76 N-term E => A missense 8.277e-06 1 120822 0 0.02 0.999
fshr_human 76 N-term E => Q missense 1.656e-05 2 120808 0 0.02 0.996
fshr_human 72 N-term L => Q missense 8.255e-06 1 121138 0 0.0 0.992
fshr_human 70 N-term G => A missense 0.0006604 80 121136 0 0.4 0.047
fshr_human 69 N-term F => C missense 8.255e-06 1 121146 0 0.0 0.985
fshr_human 65 N-term A => V missense 1.651e-05 2 121128 0 0.05 0.2
fshr_human 62 N-term Q => H missense 8.257e-06 1 121104 0 0.0 0.719
fshr_human 61 N-term I => N missense 1.652e-05 2 121078 0 0.0 0.999
fshr_human 60 N-term V => A missense 8.26e-06 1 121060 0 0.06 0.221
fshr_human 60 N-term V => I missense 1.652e-05 2 121054 0 0.13 0.042
fshr_human 53 N-term F => S missense 1.655e-05 2 120866 0 0.0 0.99
fshr_human 51 N-term L => M missense 8.284e-06 1 120708 0 0.01 0.919
fshr_human 49 N-term I => T missense 8.28e-06 1 120766 0 0.63 0.002
fshr_human 48 N-term A => V missense 8.282e-06 1 120738 0 0.06 0.141
fshr_human 47 N-term N => K missense 8.278e-06 1 120796 0 0.01 0.871
fshr_human 46 N-term R => K missense 8.279e-06 1 120784 0 0.26 0.037
fshr_human 45 N-term P => R missense 8.282e-06 1 120744 0 0.0 0.999
fshr_human 45 N-term P => L missense 8.282e-06 1 120744 0 0.0 0.997
fshr_human 43 N-term D => E missense 8.278e-06 1 120808 0 0.05 0.538
fshr_human 28 N-term R => S missense 9.102e-05 11 120848 0 0.1 0.254
fshr_human 21 N-term R => Q missense 1.654e-05 2 120888 0 0.33 0.009
fshr_human 21 N-term R => W missense 8.271e-06 1 120902 0 0.04 0.011
fshr_human 12 N-term L => R missense 8.27e-06 1 120926 0 nan 0.003
fshr_human 11 N-term F => V missense 6.615e-05 8 120930 0 nan 0.001
fshr_human 10 N-term A => T missense 8.27e-06 1 120912 0 nan 0.263
fshr_human 9 N-term L => V missense 6.616e-05 8 120916 0 nan 0.001
fshr_human 8 N-term L => F missense 0.0009263 112 120914 0 0.26 0.025
fshr_human 7 N-term S => P missense 8.271e-06 1 120898 0 nan 0.025
fshr_human 4 N-term L => F missense 2.482e-05 3 120856 0 0.1 0.354


Residue

Diagrams

ICL1 Q Y K L T ICL1ECL1 S Q Y H N Y A I D W Q T ECL1ICL2 A M Q L D C K V ICL2ECL2 I S S Y M K V S I C L P M D I D ECL2ICL3 N P N I V ICL3ECL3 V P L I ECL3N-term M A L L L V S L L A F L S L G S G C H H R I C H C S N R V F L C Q E S K V T E I P S D L P R N A I E L R F V L T K L R V I Q K G A F S G F G D L E K I E I S Q N D V L E V I E A D V F S N L P K L H E I R I E K A N N L L Y I N P E A F Q N L P N L Q Y L L I S N T G I K H L P D V H K I H S L Q K V L L D I Q D N I N I H T I E R N S F V G L S F E S V I L W L N K N G I Q E I H N C A F N G T Q L D E L N L S D N N N L E E L P N D V F H G A S G P V I L D I S R T R I H S L P S Y G L E N L K K L R A R S T Y N L K K L P T L E K L V A L M E A S L T Y P S H C C A F A N W R R Q I S E L H P I C N K S I L R Q E V D Y M T Q A R G Q R S S L A E D N E S S Y S R G F D M T Y T E F D Y D L C N E V V D V T C S P K P D A F N P C E D I M G N-termC-term C Y E M Q A Q I Y R T E T S S T V H N T H P R N G H C S S A P R V T N G S T Y I L V P L S H L A Q N C-term Y N I L R V L I W F I S I L A I T G N I I V L V I L T T S V P R F L M C N L A F A D L C I G I Y L L L I A S V D I H T K G A G C D A A G F F T V F A S E L S V Y T L T A I T L E R W H T I T H Q L R H A A S V M V M G W I F A F A A A L F P I F G S P L S Q L Y V M S L L V L N V L A F V V I C G C Y I H I Y L T V R S S S S D T R I A K R M A M L I F T D F L C M A P I S F F A I S A S L K T V S K A K I L L V L F H P I N S C A N P F L Y A I F T K N F F I C G F R R D L L S K
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