GPCRdb

Variation Browser

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Receptor	Position	GPCRdb	Segment	Variant	Mutation type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation


Receptor	Position	GPCRdb	Segment	Variant	Mutation Type	Allele Frequency	Allele Count	Allele Number	Homozygotes	SIFT score	PolyPhen score	Functional annotation
pe2r3_human	374		C-term	L => LysfsTer48	frameshift	8.25e-06	1	121206	0	None	None
pe2r3_human	389		C-term	E => ValfsTer20	frameshift	8.243e-06	1	121308	0	None	None
pe2r3_human	388		C-term	L => SerfsTer21	frameshift	2.473e-05	3	121330	0	None	None
pe2r3_human	380		C-term	S => Ter	stop gained	0.0005098	5	9808	0	None	None
pe2r3_human	7		N-term	Y => Ter	stop gained	4.236e-05	1	23606	0	None	None	PTM (Phosphorylation)
pe2r3_human	389		C-term	E => V	missense	8.305e-06	1	120414	0	nan	0.025
pe2r3_human	387		C-term	H => L	missense	4.144e-05	5	120654	0	nan	0.0
pe2r3_human	386		C-term	D => N	missense	1.657e-05	2	120698	0	nan	0.003
pe2r3_human	381		C-term	T => I	missense	8.271e-06	1	120910	0	nan	0.031
pe2r3_human	380		C-term	S => L	missense	8.271e-06	1	120908	0	nan	0.916
pe2r3_human	380		C-term	S => A	missense	8.27e-06	1	120926	0	nan	0.746
pe2r3_human	378		C-term	C => R	missense	8.27e-06	1	120920	0	nan	0.058
pe2r3_human	375		C-term	P => L	missense	0.001406	170	120912	2	nan	0.987
pe2r3_human	375		C-term	P => H	missense	8.27e-06	1	120912	0	nan	0.994
pe2r3_human	371		C-term	S => F	missense	1.655e-05	2	120882	0	0.0	0.974
pe2r3_human	369	8.66x66	H8	S => F	missense	8.273e-06	1	120868	0	0.04	0.974
pe2r3_human	366	8.63x63	H8	N => S	missense	0.004826	583	120806	9	0.59	0.001
pe2r3_human	365	8.62x62	H8	N => S	missense	1.656e-05	2	120786	0	1.0	0.001
pe2r3_human	355	8.52x52	H8	R => Q	missense	8.244e-06	1	121306	0	0.12	0.132
pe2r3_human	320	7.27x26	TM7	E => K	missense	8.249e-06	1	121220	0	0.26	0.41
pe2r3_human	319	7.26x25	TM7	T => M	missense	0.0003382	41	121218	0	0.1	0.046
pe2r3_human	319	7.26x25	TM7	T => K	missense	8.25e-06	1	121218	0	0.52	0.069
pe2r3_human	314		ECL3	H => P	missense	8.253e-06	1	121168	0	0.05	0.811
pe2r3_human	310	6.63x63	TM6	T => I	missense	1.652e-05	2	121082	0	0.04	0.14
pe2r3_human	310	6.63x63	TM6	T => A	missense	1.652e-05	2	121068	0	0.1	0.403
pe2r3_human	301	6.54x54	TM6	M => K	missense	3.343e-05	4	119662	0	0.03	0.572
pe2r3_human	293	6.46x46	TM6	V => I	missense	9.09e-06	1	110012	0	1.0	0.123
pe2r3_human	290	6.43x43	TM6	V => M	missense	8.96e-06	1	111606	0	0.0	0.999
pe2r3_human	286	6.39x39	TM6	G => A	missense	3.517e-05	4	113726	0	0.0	1.0
pe2r3_human	285	6.38x38	TM6	M => I	missense	8.757e-06	1	114196	0	0.03	0.403
pe2r3_human	283	6.36x36	TM6	Q => H	missense	8.683e-06	1	115174	0	0.0	1.0	GP (contact)
pe2r3_human	280	6.33x33	TM6	T => M	missense	8.549e-06	1	116966	0	0.6	1.0	GP (contact)
pe2r3_human	279	6.32x32	TM6	E => K	missense	8.506e-06	1	117564	0	0.0	1.0	GP (contact)
pe2r3_human	274	6.27x27	TM6	G => S	missense	8.369e-06	1	119492	0	0.33	0.973
pe2r3_human	270	6.23x23	TM6	S => R	missense	1.665e-05	2	120152	0	0.17	0.158
pe2r3_human	269	6.22x22	TM6	S => T	missense	8.316e-06	1	120250	0	0.09	0.84
pe2r3_human	264	5.73x73	TM5	A => T	missense	8.294e-06	1	120568	0	0.28	0.145
pe2r3_human	262	5.71x71	TM5	A => T	missense	3.316e-05	4	120626	0	0.57	0.241	GP (contact)
pe2r3_human	255	5.64x64	TM5	A => T	missense	8.275e-06	1	120844	0	0.28	0.995	GP (contact)
pe2r3_human	239	5.48x48	TM5	L => F	missense	1.66e-05	2	120514	0	0.0	0.995
pe2r3_human	236	5.45x45	TM5	F => L	missense	8.319e-06	1	120212	0	0.77	0.152
pe2r3_human	235	5.44x44	TM5	A => V	missense	2.498e-05	3	120090	0	0.0	0.986
pe2r3_human	233	5.42x42	TM5	A => T	missense	8.358e-06	1	119646	0	0.46	0.016
pe2r3_human	231	5.40x40	TM5	A => V	missense	8.375e-06	1	119408	0	0.3	0.995
pe2r3_human	231	5.40x40	TM5	A => T	missense	8.38e-06	1	119326	0	0.06	0.986
pe2r3_human	228	5.37x37	TM5	L => F	missense	2.523e-05	3	118904	0	0.02	0.689
pe2r3_human	226	5.35x35	TM5	G => C	missense	8.445e-06	1	118420	0	0.02	0.998
pe2r3_human	226	5.35x35	TM5	G => S	missense	1.689e-05	2	118420	0	0.14	0.973
pe2r3_human	224		ECL2	N => Y	missense	8.46e-06	1	118208	0	0.02	0.56
pe2r3_human	218		ECL2	G => V	missense	8.534e-06	1	117184	0	0.02	0.752
pe2r3_human	218		ECL2	G => R	missense	8.537e-06	1	117132	0	0.01	0.842
pe2r3_human	216		ECL2	G => S	missense	8.574e-06	1	116630	0	0.13	0.861
pe2r3_human	215		ECL2	G => R	missense	8.586e-06	1	116466	0	0.12	0.984
pe2r3_human	213		ECL2	G => W	missense	1.727e-05	2	115792	0	0.01	0.996
pe2r3_human	200		ECL2	T => A	missense	2.582e-05	3	116200	0	0.13	0.12
pe2r3_human	198		ECL2	Q => H	missense	2.586e-05	3	116018	0	0.15	0.033
pe2r3_human	196		ECL2	V => M	missense	8.659e-06	1	115492	0	0.01	0.995
pe2r3_human	182	4.50x50	TM4	W => C	missense	9.017e-06	1	110906	0	0.02	0.998
pe2r3_human	181	4.49x49	TM4	V => L	missense	4.545e-05	5	110020	0	0.12	0.906
pe2r3_human	181	4.49x49	TM4	V => M	missense	2.727e-05	3	110020	0	0.01	0.903
pe2r3_human	179	4.47x47	TM4	L => F	missense	9.264e-06	1	107944	0	0.17	0.16
pe2r3_human	176	4.44x44	TM4	A => G	missense	9.513e-06	1	105120	0	0.21	0.314
pe2r3_human	175	4.43x43	TM4	R => L	missense	7.748e-05	8	103252	0	0.0	0.804
pe2r3_human	173	4.41x41	TM4	A => T	missense	1.006e-05	1	99406	0	0.4	0.507
pe2r3_human	172	4.40x40	TM4	R => L	missense	1.006e-05	1	99374	0	0.04	0.899
pe2r3_human	172	4.40x40	TM4	R => G	missense	1.018e-05	1	98216	0	0.05	0.191
pe2r3_human	169	34.57x57	ICL2	M => L	missense	6.482e-05	6	92570	0	0.14	0.044	GP (contact)
pe2r3_human	169	34.57x57	ICL2	M => V	missense	1.08e-05	1	92570	0	0.48	0.129	GP (contact)
pe2r3_human	167	34.55x55	ICL2	S => C	missense	1.124e-05	1	88998	0	0.02	0.289	GP (contact)
pe2r3_human	164	34.52x52	ICL2	W => R	missense	1.217e-05	1	82178	0	0.0	0.998	GP (contact)
pe2r3_human	163	34.51x51	ICL2	H => Q	missense	1.224e-05	1	81666	0	0.03	1.0	GP (contact)
pe2r3_human	151	3.46x46	TM3	M => V	missense	1.498e-05	1	66762	0	0.0	0.998
pe2r3_human	147	3.42x42	TM3	I => T	missense	1.537e-05	1	65066	0	0.0	0.752
pe2r3_human	147	3.42x42	TM3	I => L	missense	4.599e-05	3	65236	0	1.0	0.047
pe2r3_human	144	3.39x39	TM3	S => P	missense	1.557e-05	1	64216	0	1.0	0.05
pe2r3_human	125		ECL1	P => S	missense	1.697e-05	1	58926	0	0.16	0.189
pe2r3_human	123		ECL1	I => V	missense	1.698e-05	1	58898	0	0.45	0.006
pe2r3_human	119	23.49x49	ECL1	R => P	missense	1.718e-05	1	58218	0	0.26	0.026
pe2r3_human	119	23.49x49	ECL1	R => C	missense	1.718e-05	1	58222	0	0.03	0.892
pe2r3_human	118		ECL1	Q => E	missense	1.722e-05	1	58084	0	0.66	0.309
pe2r3_human	113	2.64x63	TM2	V => A	missense	1.756e-05	1	56952	0	0.01	0.927
pe2r3_human	112	2.63x62	TM2	V => F	missense	0.000158	9	56972	0	0.71	0.041
pe2r3_human	94	2.45x45	TM2	W => C	missense	1.535e-05	1	65154	0	0.08	0.033
pe2r3_human	94	2.45x45	TM2	W => G	missense	0.000363	24	66122	0	0.3	0.013
pe2r3_human	92	2.43x43	TM2	I => V	missense	1.461e-05	1	68434	0	0.21	0.951
pe2r3_human	85	2.36x36	TM2	K => R	missense	8.195e-05	6	73212	0	0.01	0.521
pe2r3_human	83		ICL1	K => N	missense	1.34e-05	1	74616	0	0.0	0.827
pe2r3_human	83		ICL1	K => T	missense	0.0001065	8	75090	0	0.02	0.259
pe2r3_human	82		ICL1	S => T	missense	1.316e-05	1	75974	0	0.05	0.752
pe2r3_human	82		ICL1	S => C	missense	1.305e-05	1	76600	0	0.01	0.967
pe2r3_human	81		ICL1	E => V	missense	1.295e-05	1	77248	0	0.0	0.997
pe2r3_human	81		ICL1	E => Q	missense	1.29e-05	1	77530	0	0.02	0.994
pe2r3_human	80		ICL1	R => Q	missense	1.279e-05	1	78166	0	0.34	0.888
pe2r3_human	70	1.54x54	TM1	M => V	missense	2.167e-05	2	92280	0	0.0	0.378
pe2r3_human	53	1.37x37	TM1	A => V	missense	2.013e-05	2	99346	0	0.25	0.018
pe2r3_human	45		N-term	E => K	missense	1.057e-05	1	94600	0	0.19	0.294
pe2r3_human	44		N-term	G => A	missense	1.065e-05	1	93890	0	0.37	0.003
pe2r3_human	42		N-term	G => R	missense	0.0004063	37	91060	0	0.25	0.013
pe2r3_human	39		N-term	R => S	missense	1.145e-05	1	87350	0	0.4	0.011
pe2r3_human	38		N-term	T => K	missense	1.145e-05	1	87356	0	0.01	0.693
pe2r3_human	34		N-term	R => P	missense	3.734e-05	3	80334	0	0.17	0.024
pe2r3_human	33		N-term	A => E	missense	0.0001375	11	79974	0	0.22	0.021
pe2r3_human	28		N-term	E => Q	missense	4.231e-05	3	70910	0	0.06	0.104
pe2r3_human	28		N-term	E => K	missense	1.41e-05	1	70910	0	0.09	0.216
pe2r3_human	24		N-term	M => V	missense	1.513e-05	1	66074	0	nan	0.02
pe2r3_human	19		N-term	H => Y	missense	1.909e-05	1	52388	0	0.04	0.111
pe2r3_human	17		N-term	L => F	missense	2.019e-05	1	49526	0	0.05	0.031
pe2r3_human	16		N-term	R => H	missense	6.224e-05	3	48202	0	0.04	0.03
pe2r3_human	16		N-term	R => S	missense	2.19e-05	1	45672	0	0.07	0.507
pe2r3_human	14		N-term	C => R	missense	0.0001292	5	38690	0	nan	0.979
pe2r3_human	8		N-term	G => E	missense	3.792e-05	1	26374	0	0.05	0.466
pe2r3_human	5		N-term	R => Q	missense	4.805e-05	1	20812	0	nan	0.968

Residue

deleterious missense variants are shown in red
tolerated missense variants are shown in green
loss of function mutations ('stop gained' or 'frameshift' in the coding region) are shown in blue

Diagrams

SnakePlot Download: PNG | SVG
HelixBox Download: PNG | SVG

Versions

Package	Name	Version
Django		2.2.1
Python		3.6.7
debug_toolbar	Debug Toolbar	1.11
polymorphic	Polymorphic	2.0.3
rest_framework	Django REST framework	3.9.3
rest_framework_swagger	Rest_Framework_Swagger	2.2.0

Time

Resource usage

Resource	Value
User CPU time	145.006 msec
System CPU time	3.879 msec
Total CPU time	148.885 msec
Elapsed time	157.340 msec
Context switches	10 voluntary, 1 involuntary

Browser timing

Timing attribute	Timeline	Milliseconds since navigation start (+length)

Settings from `protwis.settings`

Setting	Value
ABSOLUTE_URL_OVERRIDES	`{}`
ADMINS	`[]`
ALLOWED_HOSTS	`['*']`
APPEND_SLASH	`True`
AUTHENTICATION_BACKENDS	`['django.contrib.auth.backends.ModelBackend']`
AUTH_PASSWORD_VALIDATORS	`'********************'`
AUTH_USER_MODEL	`'auth.User'`
BASE_DIR	`'/home/protwis/gpcrdb_test'`
BUILD_CACHE_DIR	`'/home/protwis/gpcrdb_data/cache'`
CACHES	`{'alignments': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test_alignment', 'OPTIONS': {'MAX_ENTRIES': 1000}}, 'default': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test/', 'OPTIONS': {'MAX_ENTRIES': 10000000}}}`
CACHE_MIDDLEWARE_ALIAS	`'default'`
CACHE_MIDDLEWARE_KEY_PREFIX	`'********************'`
CACHE_MIDDLEWARE_SECONDS	`600`
CSRF_COOKIE_AGE	`31449600`
CSRF_COOKIE_DOMAIN	`None`
CSRF_COOKIE_HTTPONLY	`False`
CSRF_COOKIE_NAME	`'csrftoken'`
CSRF_COOKIE_PATH	`'/'`
CSRF_COOKIE_SAMESITE	`'Lax'`
CSRF_COOKIE_SECURE	`False`
CSRF_FAILURE_VIEW	`'django.views.csrf.csrf_failure'`
CSRF_HEADER_NAME	`'HTTP_X_CSRFTOKEN'`
CSRF_TRUSTED_ORIGINS	`[]`
CSRF_USE_SESSIONS	`False`
DATABASES	`{'default': {'ATOMIC_REQUESTS': False, 'AUTOCOMMIT': True, 'CONN_MAX_AGE': 0, 'ENGINE': 'django.db.backends.postgresql_psycopg2', 'HOST': 'localhost', 'NAME': 'protwis_202107', 'OPTIONS': {}, 'PASSWORD': '********************', 'PORT': '', 'TEST': {'CHARSET': None, 'COLLATION': None, 'MIRROR': None, 'NAME': None}, 'TIME_ZONE': None, 'USER': 'protwis'}}`
DATABASE_ROUTERS	`[]`
DATA_DIR	`'/home/protwis/gpcrdb_data'`
DATA_UPLOAD_MAX_MEMORY_SIZE	`2621440`
DATA_UPLOAD_MAX_NUMBER_FIELDS	`1000`
DATETIME_FORMAT	`'N j, Y, P'`
DATETIME_INPUT_FORMATS	`['%Y-%m-%d %H:%M:%S', '%Y-%m-%d %H:%M:%S.%f', '%Y-%m-%d %H:%M', '%Y-%m-%d', '%m/%d/%Y %H:%M:%S', '%m/%d/%Y %H:%M:%S.%f', '%m/%d/%Y %H:%M', '%m/%d/%Y', '%m/%d/%y %H:%M:%S', '%m/%d/%y %H:%M:%S.%f', '%m/%d/%y %H:%M', '%m/%d/%y']`
DATE_FORMAT	`'N j, Y'`
DATE_INPUT_FORMATS	`['%Y-%m-%d', '%m/%d/%Y', '%m/%d/%y', '%b %d %Y', '%b %d, %Y', '%d %b %Y', '%d %b, %Y', '%B %d %Y', '%B %d, %Y', '%d %B %Y', '%d %B, %Y']`
DEBUG	`True`
DEBUG_PROPAGATE_EXCEPTIONS	`False`
DEBUG_TOOLBAR_PATCH_SETTINGS	`False`
DECIMAL_SEPARATOR	`'.'`
DEFAULT_CHARSET	`'utf-8'`
DEFAULT_CONTENT_TYPE	`'text/html'`
DEFAULT_EXCEPTION_REPORTER_FILTER	`'django.views.debug.SafeExceptionReporterFilter'`
DEFAULT_FILE_STORAGE	`'django.core.files.storage.FileSystemStorage'`
DEFAULT_FROM_EMAIL	`'webmaster@localhost'`
DEFAULT_INDEX_TABLESPACE	`''`
DEFAULT_NUMBERING_SCHEME	`'gpcrdb'`
DEFAULT_PROTEIN_STATE	`'inactive'`
DEFAULT_SITE	`'gpcr'`
DEFAULT_TABLESPACE	`''`
DISALLOWED_USER_AGENTS	`[]`
DOCUMENTATION_URL	`'https://docs.gpcrdb.org/'`
EMAIL_BACKEND	`'django.core.mail.backends.smtp.EmailBackend'`
EMAIL_HOST	`'localhost'`
EMAIL_HOST_PASSWORD	`'********************'`
EMAIL_HOST_USER	`''`
EMAIL_PORT	`25`
EMAIL_SSL_CERTFILE	`None`
EMAIL_SSL_KEYFILE	`'********************'`
EMAIL_SUBJECT_PREFIX	`'[Django] '`
EMAIL_TIMEOUT	`None`
EMAIL_USE_LOCALTIME	`False`
EMAIL_USE_SSL	`False`
EMAIL_USE_TLS	`False`
FILE_CHARSET	`'utf-8'`
FILE_UPLOAD_DIRECTORY_PERMISSIONS	`None`
FILE_UPLOAD_HANDLERS	`['django.core.files.uploadhandler.MemoryFileUploadHandler', 'django.core.files.uploadhandler.TemporaryFileUploadHandler']`
FILE_UPLOAD_MAX_MEMORY_SIZE	`2621440`
FILE_UPLOAD_PERMISSIONS	`None`
FILE_UPLOAD_TEMP_DIR	`None`
FIRST_DAY_OF_WEEK	`0`
FIXTURE_DIRS	`[]`
FORCE_SCRIPT_NAME	`None`
FORMAT_MODULE_PATH	`None`
FORM_RENDERER	`'django.forms.renderers.DjangoTemplates'`
GOOGLE_ANALYTICS_API	`'********************'`
GOOGLE_ANALYTICS_KEY	`'********************'`
IGNORABLE_404_URLS	`[]`
INSTALLED_APPS	('django.contrib.admin', 'django.contrib.auth', 'django.contrib.contenttypes', 'django.contrib.sessions', 'django.contrib.messages', 'django.contrib.staticfiles', 'django.contrib.humanize', 'debug_toolbar', 'rest_framework', 'rest_framework_swagger', 'polymorphic', 'common', 'api', 'news', 'pages', 'home', 'protein', 'family', 'residue', 'alignment', 'similaritysearch', 'similaritymatrix', 'structure', 'ligand', 'interaction', 'mutation', 'phylogenetic_trees', 'sitesearch', 'build_gpcr', 'construct', 'tools', 'drugs', 'signprot', 'signprot2', 'mutational_landscape', 'contactnetwork', 'seqsign', 'angles', 'hotspots')
INTERNAL_IPS	`'10.0.2.2'`
LANGUAGES	[('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')]
LANGUAGES_BIDI	`['he', 'ar', 'fa', 'ur']`
LANGUAGE_CODE	`'en-us'`
LANGUAGE_COOKIE_AGE	`None`
LANGUAGE_COOKIE_DOMAIN	`None`
LANGUAGE_COOKIE_NAME	`'django_language'`
LANGUAGE_COOKIE_PATH	`'/'`
LOCALE_PATHS	`[]`
LOGGING	{'disable_existing_loggers': False, 'formatters': {'verbose': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s] %(message)s'}, 'verbose_low': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s]'}}, 'handlers': {'build': {'class': 'logging.FileHandler', 'filename': 'logs/build.log', 'formatter': 'verbose', 'level': 'DEBUG'}, 'django': {'class': 'logging.FileHandler', 'filename': 'logs/django.log', 'formatter': 'verbose', 'level': 'WARNING'}, 'protwis': {'class': 'logging.FileHandler', 'filename': 'logs/protwis.log', 'formatter': 'verbose', 'level': 'DEBUG'}}, 'loggers': {'build': {'handlers': ['build'], 'level': 'DEBUG'}, 'django': {'handlers': ['django'], 'level': 'WARNING', 'propagate': True}, 'protwis': {'handlers': ['protwis'], 'level': 'DEBUG'}}, 'version': 1}
LOGGING_CONFIG	`'logging.config.dictConfig'`
LOGIN_REDIRECT_URL	`'/accounts/profile/'`
LOGIN_URL	`'/accounts/login/'`
LOGOUT_REDIRECT_URL	`None`
MANAGERS	`[]`
MEDIA_ROOT	`'/protwis/media/protwis'`
MEDIA_URL	`'/media/'`
MESSAGE_STORAGE	`'django.contrib.messages.storage.fallback.FallbackStorage'`
MIDDLEWARE	`('common.middleware.stats.StatsMiddleware', 'debug_toolbar.middleware.DebugToolbarMiddleware', 'django.contrib.sessions.middleware.SessionMiddleware', 'django.middleware.common.CommonMiddleware', 'django.middleware.csrf.CsrfViewMiddleware', 'django.contrib.auth.middleware.AuthenticationMiddleware', 'django.contrib.messages.middleware.MessageMiddleware', 'django.middleware.clickjacking.XFrameOptionsMiddleware')`
MIGRATION_MODULES	`{}`
MONTH_DAY_FORMAT	`'F j'`
NUMBER_GROUPING	`0`
PASSWORD_HASHERS	`'********************'`
PASSWORD_RESET_TIMEOUT_DAYS	`'********************'`
PREPEND_WWW	`False`
REFERENCE_POSITIONS	`{'D1S1': 'D1S1x50', 'D1S2': 'D1S2x50', 'D1T1': 'D1T1x50', 'D1e1': 'D1e1x50', 'ECL1': '23x50', 'ECL2': '45x50', 'H8': '8x50', 'ICL1': '12x50', 'ICL2': '34x50', 'TM1': '1x50', 'TM2': '2x50', 'TM3': '3x50', 'TM4': '4x50', 'TM5': '5x50', 'TM6': '6x50', 'TM7': '7x50'}`
ROOT_URLCONF	`'protwis.urls'`
SECRET_KEY	`'********************'`
SECURE_BROWSER_XSS_FILTER	`False`
SECURE_CONTENT_TYPE_NOSNIFF	`False`
SECURE_HSTS_INCLUDE_SUBDOMAINS	`False`
SECURE_HSTS_PRELOAD	`False`
SECURE_HSTS_SECONDS	`0`
SECURE_PROXY_SSL_HEADER	`None`
SECURE_REDIRECT_EXEMPT	`[]`
SECURE_SSL_HOST	`None`
SECURE_SSL_REDIRECT	`False`
SERVER_EMAIL	`'root@localhost'`
SESSION_CACHE_ALIAS	`'default'`
SESSION_COOKIE_AGE	`86400`
SESSION_COOKIE_DOMAIN	`None`
SESSION_COOKIE_HTTPONLY	`True`
SESSION_COOKIE_NAME	`'sessionid'`
SESSION_COOKIE_PATH	`'/'`
SESSION_COOKIE_SAMESITE	`'Lax'`
SESSION_COOKIE_SECURE	`False`
SESSION_ENGINE	`'django.contrib.sessions.backends.db'`
SESSION_EXPIRE_AT_BROWSER_CLOSE	`False`
SESSION_FILE_PATH	`None`
SESSION_SAVE_EVERY_REQUEST	`False`
SESSION_SERIALIZER	`'django.contrib.sessions.serializers.PickleSerializer'`
SETTINGS_MODULE	`'protwis.settings'`
SHORT_DATETIME_FORMAT	`'m/d/Y P'`
SHORT_DATE_FORMAT	`'m/d/Y'`
SIGNING_BACKEND	`'django.core.signing.TimestampSigner'`
SILENCED_SYSTEM_CHECKS	`[]`
SITE_NAME	`'gpcr'`
SITE_TITLE	`'GPCRdb'`
STATICFILES_DIRS	`('/home/protwis/gpcrdb_test/static',)`
STATICFILES_FINDERS	`['django.contrib.staticfiles.finders.FileSystemFinder', 'django.contrib.staticfiles.finders.AppDirectoriesFinder']`
STATICFILES_STORAGE	`'django.contrib.staticfiles.storage.StaticFilesStorage'`
STATIC_ROOT	`'/home/protwis/static_test/'`
STATIC_URL	`'/static/'`
SWAGGER_SETTINGS	`{'USE_SESSION_AUTH': False}`
TEMPLATES	[{'APP_DIRS': True, 'BACKEND': 'django.template.backends.django.DjangoTemplates', 'DIRS': [], 'OPTIONS': {'context_processors': ['django.contrib.auth.context_processors.auth', 'django.template.context_processors.debug', 'django.template.context_processors.i18n', 'django.template.context_processors.media', 'django.template.context_processors.static', 'django.template.context_processors.tz', 'django.contrib.messages.context_processors.messages', 'protwis.context_processors.current_site', 'protwis.context_processors.canonical_tag', 'protwis.context_processors.documentation_url', 'protwis.context_processors.google_analytics', 'protwis.context_processors.site_title'], 'debug': True}}]
TEST_NON_SERIALIZED_APPS	`[]`
TEST_RUNNER	`'django.test.runner.DiscoverRunner'`
THOUSAND_SEPARATOR	`','`
TIME_FORMAT	`'P'`
TIME_INPUT_FORMATS	`['%H:%M:%S', '%H:%M:%S.%f', '%H:%M']`
TIME_ZONE	`'Europe/Copenhagen'`
USE_I18N	`True`
USE_L10N	`True`
USE_THOUSAND_SEPARATOR	`False`
USE_TZ	`True`
USE_X_FORWARDED_HOST	`False`
USE_X_FORWARDED_PORT	`False`
WSGI_APPLICATION	`None`
X_FRAME_OPTIONS	`'SAMEORIGIN'`
YEAR_MONTH_FORMAT	`'F Y'`

Headers

Request headers

Key	Value
Accept	text/html,application/xhtml+xml,application/xml;q=0.9,/;q=0.8
Accept-Encoding	br,gzip
Accept-Language	en-US,en;q=0.5
Connection	close
Host	test.gpcrdb.org
User-Agent	CCBot/2.0 (https://commoncrawl.org/faq/)
X-Forwarded-For	3.236.207.90
X-Forwarded-Proto	https
X-Real-Ip	3.236.207.90

Response headers

Key	Value
Content-Length	498092
Content-Type	text/html; charset=utf-8
Vary	Cookie
X-Frame-Options	SAMEORIGIN

WSGI environ

Since the WSGI environ inherits the environment of the server, only a significant subset is shown below.

Key	Value
PATH_INFO	/mutational_landscape/protein/PE2R3_human/
QUERY_STRING
REMOTE_ADDR
REQUEST_METHOD	GET
SCRIPT_NAME
SERVER_NAME	test.gpcrdb.org
SERVER_PORT	443
SERVER_PROTOCOL	HTTP/1.0
SERVER_SOFTWARE	gunicorn/19.9.0

Request

View information

View function	Arguments	Keyword arguments	URL name
`mutational_landscape.views.render_variants`	`()`	`{'protein': 'PE2R3_human'}`	`render`

No cookies

No session data

No GET data

No POST data

SQL queries from 1 connection

default 2.56 ms (1 query )

	Query	Timeline	Time (ms)	Action
	+	SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 'pe2r3_human'	100.0%	2.56
	Connection: default /usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89) proteins.append(Protein.objects.get(entry_name=protein.lower()))

Query

Timeline

Time (ms)

Action

SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 'pe2r3_human'

100.0%

2.56

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89)
  proteins.append(Protein.objects.get(entry_name=protein.lower()))

Static files (590 found, 40 used)

Static file path

/home/protwis/gpcrdb_test/static

Static file apps

django.contrib.admin
debug_toolbar
rest_framework
rest_framework_swagger
polymorphic

Static files

bootstrap/css/bootstrap.min.css: /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-submenu.min.css: /home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
home/css/jquery-ui.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery-ui.min.css
home/css/jquery-ui.theme.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery-ui.theme.min.css
home/css/bootstrap-treeview.min.css: /home/protwis/gpcrdb_test/static/home/css/bootstrap-treeview.min.css
home/css/style.css: /home/protwis/gpcrdb_test/static/home/css/style.css
flowplayer/flowplayer.css: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
home/css/cookieconsent.min.css: /home/protwis/gpcrdb_test/static/home/css/cookieconsent.min.css
home/css/jquery.dataTables.min.css: /home/protwis/gpcrdb_test/static/home/css/jquery.dataTables.min.css
home/css/structure_browser.css: /home/protwis/gpcrdb_test/static/home/css/structure_browser.css
home/css/residue_table.css: /home/protwis/gpcrdb_test/static/home/css/residue_table.css
home/css/alignment.css: /home/protwis/gpcrdb_test/static/home/css/alignment.css
: /home/protwis/gpcrdb_test/static
home/css/mainmenu.css: /home/protwis/gpcrdb_test/static/home/css/mainmenu.css
home/css/modal.css: /home/protwis/gpcrdb_test/static/home/css/modal.css
home/css/jquery.powertip.css: /home/protwis/gpcrdb_test/static/home/css/jquery.powertip.css
home/js/jquery-3.1.1.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/citation_tool.js: /home/protwis/gpcrdb_test/static/home/js/citation_tool.js
home/js/joinus_tool.js: /home/protwis/gpcrdb_test/static/home/js/joinus_tool.js
home/js/jquery-3.1.1.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/jquery-ui.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery-ui.min.js
bootstrap/js/bootstrap.min.js: /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/js/bootstrap-submenu.js: /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
home/js/navbar-autocomplete.js: /home/protwis/gpcrdb_test/static/home/js/navbar-autocomplete.js
home/js/svg-pan-zoom.min.js: /home/protwis/gpcrdb_test/static/home/js/svg-pan-zoom.min.js
home/js/bootstrap-treeview.min.js: /home/protwis/gpcrdb_test/static/home/js/bootstrap-treeview.min.js
home/js/papaparse.min.js: /home/protwis/gpcrdb_test/static/home/js/papaparse.min.js
flowplayer/flowplayer.min.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.min.js
flowplayer/flowplayer.overlay.min.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.min.js
flowplayer/flowplayer.overlay.bootstrap.js: /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.bootstrap.js
home/js/gpcrdb.js: /home/protwis/gpcrdb_test/static/home/js/gpcrdb.js
home/js/cookieconsent.min.js: /home/protwis/gpcrdb_test/static/home/js/cookieconsent.min.js
home/js/jquery.dataTables.min.js: /home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.min.js
home/js/dataTables.tableTools.min.js: /home/protwis/gpcrdb_test/static/home/js/dataTables.tableTools.min.js
home/js/jquery.dataTables.columnFilter.js: /home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.columnFilter.js
home/js/selection.js: /home/protwis/gpcrdb_test/static/home/js/selection.js
home/js/saveSvgAsPng.js: /home/protwis/gpcrdb_test/static/home/js/saveSvgAsPng.js
home/js/alignment.js: /home/protwis/gpcrdb_test/static/home/js/alignment.js
home/js/diagrams.js: /home/protwis/gpcrdb_test/static/home/js/diagrams.js
home/js/residuetable.js: /home/protwis/gpcrdb_test/static/home/js/residuetable.js

django.contrib.staticfiles.finders.FileSystemFinder (415 files)

Path	Location
visualization_scripts/maestro_label_generic_numbers.py	/home/protwis/gpcrdb_test/static/visualization_scripts/maestro_label_generic_numbers.py
visualization_scripts/pymol_view_generic_numbers.pml	/home/protwis/gpcrdb_test/static/visualization_scripts/pymol_view_generic_numbers.pml
bootstrap/js/npm.js	/home/protwis/gpcrdb_test/static/bootstrap/js/npm.js
bootstrap/js/bootstrap.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.js
bootstrap/js/bootstrap-submenu.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
bootstrap/js/bootstrap.min.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/fonts/glyphicons-halflings-regular.eot	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.eot
bootstrap/fonts/glyphicons-halflings-regular.woff	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff
bootstrap/fonts/glyphicons-halflings-regular.ttf	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.ttf
bootstrap/fonts/glyphicons-halflings-regular.svg	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.svg
bootstrap/fonts/glyphicons-halflings-regular.woff2	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff2
bootstrap/css/bootstrap.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css.map
bootstrap/css/bootstrap-submenu.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css
bootstrap/css/bootstrap.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css
bootstrap/css/bootstrap-theme.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css.map
bootstrap/css/bootstrap-theme.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css.map
bootstrap/css/bootstrap-submenu.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
bootstrap/css/bootstrap.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css.map
bootstrap/css/bootstrap-submenu.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css.map
bootstrap/css/bootstrap.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-theme.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css
bootstrap/css/bootstrap-theme.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css
blast/protwis_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psq
blast/protwis_human_bundle_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pin
blast/protwis_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pin
blast/protwis_human_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.phr
blast/protwis_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psd
blast/protwis_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.phr
blast/protwis_human_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psq
blast/protwis_human_gpcr_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.phr
blast/protwis_human_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psq
blast/protwis_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psd
blast/protwis_human_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pin
blast/protwis_human_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psd
blast/protwis_human_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pog
blast/.gitignore	/home/protwis/gpcrdb_test/static/blast/.gitignore
blast/protwis_human_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psd
blast/protwis_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pog
blast/protwis_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psq
blast/protwis_human_gpcr_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psi
blast/protwis_gpcr_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.pin
blast/protwis_human_bundle_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pog
blast/protwis_human_gpcr_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.pog
blast/protwis_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psi
blast/protwis_human_bundle_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.psd
blast/protwis_human_bundle_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.psq
blast/protwis_gpcr_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.pog
blast/protwis_human_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psi
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django.contrib.staticfiles.finders.AppDirectoriesFinder (175 files)

Templates (9 rendered)

Template paths

None

Templates

browser.html: /home/protwis/gpcrdb_test/mutational_landscape/templates/browser.html; Toggle context
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'"deleterious", "#e30e0e", "GP (contact) "], "239": ' '["F", 1.66e-05, 2, 120514, 0, "missense", ' '"deleterious", "#e30e0e", ""], "236": ["L", 8.319e-06, ' '1, 120212, 0, "missense", "deleterious", "#e30e0e", ' '""], "235": ["V", 2.498e-05, 3, 120090, 0, "missense", ' '"deleterious", "#e30e0e", ""], "233": ["T", 8.358e-06, ' '1, 119646, 0, "missense", "tolerated", "#70c070", ""], ' '"231": ["T", 8.38e-06, 1, 119326, 0, "missense", ' '"deleterious", "#e30e0e", ""], "228": ["F", 2.523e-05, ' '3, 118904, 0, "missense", "deleterious", "#e30e0e", ' '""], "226": ["S", 1.689e-05, 2, 118420, 0, "missense", ' '"deleterious", "#e30e0e", ""], "224": ["Y", 8.46e-06, ' '1, 118208, 0, "missense", "deleterious", "#e30e0e", ' '""], "218": ["R", 8.537e-06, 1, 117132, 0, "missense", ' '"deleterious", "#e30e0e", ""], "216": ["S", 8.574e-06, ' '1, 116630, 0, "missense", "deleterious", "#e30e0e", ' '""], "215": ["R", 8.586e-06, 1, 116466, 0, "missense", ' '"deleterious", "#e30e0e", ""], "213": ["W", 1.727e-05, ' '2, 115792, 0, "missense", "deleterious", "#e30e0e", ' '""], "200": ["A", 2.582e-05, 3, 116200, 0, "missense", ' '"deleterious", "#e30e0e", ""], "198": ["H", 2.586e-05, ' '3, 116018, 0, "missense", "tolerated", "#70c070", ""], ' '"196": ["M", 8.659e-06, 1, 115492, 0, "missense", ' '"deleterious", "#e30e0e", ""], "182": ["C", 9.017e-06, ' '1, 110906, 0, "missense", "deleterious", "#e30e0e", ' '""], "181": ["M", 2.727e-05, 3, 110020, 0, "missense", ' '"deleterious", "#e30e0e", ""], "179": ["F", 9.264e-06, ' '1, 107944, 0, "missense", "deleterious", "#e30e0e", ' '""], "176": ["G", 9.513e-06, 1, 105120, 0, "missense", ' '"deleterious", "#e30e0e", ""], "175": ["L", 7.748e-05, ' '8, 103252, 0, "missense", "deleterious", "#e30e0e", ' '""], "173": ["T", 1.006e-05, 1, 99406, 0, "missense", ' '"deleterious", "#e30e0e", ""], "172": ["G", 1.018e-05, ' '1, 98216, 0, "missense", "deleterious", "#e30e0e", ' '""], "169": ["V", 1.08e-05, 1, 92570, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "167": ' '["C", 1.124e-05, 1, 88998, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "164": ' '["R", 1.217e-05, 1, 82178, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "163": ' '["Q", 1.224e-05, 1, 81666, 0, "missense", ' '"deleterious", "#e30e0e", "GP (contact) "], "151": ' '["V", 1.498e-05, 1, 66762, 0, "missense", ' '"deleterious", "#e30e0e", ""], "147": ["L", 4.599e-05, ' '3, 65236, 0, "missense", "tolerated", "#70c070", ""], ' '"144": ["P", 1.557e-05, 1, 64216, 0, "missense", ' '"tolerated", "#70c070", ""], "125": ["S", 1.697e-05, ' '1, 58926, 0, "missense", "deleterious", "#e30e0e", ' '""], "123": ["V", 1.698e-05, 1, 58898, 0, "missense", ' '"tolerated", "#70c070", ""], "119": ["C", 1.718e-05, ' '1, 58222, 0, "missense", "deleterious", "#e30e0e", ' '""], "118": ["E", 1.722e-05, 1, 58084, 0, "missense", ' '"deleterious", "#e30e0e", ""], "113": ["A", 1.756e-05, ' '1, 56952, 0, "missense", "deleterious", "#e30e0e", ' '""], "112": ["F", 0.000158, 9, 56972, 0, "missense", ' '"tolerated", "#70c070", ""], "94": ["G", 0.000363, 24, ' '66122, 0, "missense", "tolerated", "#70c070", ""], ' '"92": ["V", 1.461e-05, 1, 68434, 0, "missense", ' '"deleterious", "#e30e0e", ""], "85": ["R", 8.195e-05, ' '6, 73212, 0, "missense", "deleterious", "#e30e0e", ' '""], "83": ["T", 0.0001065, 8, 75090, 0, "missense", ' '"deleterious", "#e30e0e", ""], "82": ["C", 1.305e-05, ' '1, 76600, 0, "missense", "deleterious", "#e30e0e", ' '""], "81": ["Q", 1.29e-05, 1, 77530, 0, "missense", ' '"deleterious", "#e30e0e", ""], "80": ["Q", 1.279e-05, ' '1, 78166, 0, "missense", "deleterious", "#e30e0e", ' '""], "70": ["V", 2.167e-05, 2, 92280, 0, "missense", ' '"deleterious", "#e30e0e", ""], "53": ["V", 2.013e-05, ' '2, 99346, 0, "missense", "tolerated", "#70c070", ""], ' '"45": ["K", 1.057e-05, 1, 94600, 0, "missense", ' '"deleterious", "#e30e0e", ""], "44": ["A", 1.065e-05, ' '1, 93890, 0, "missense", "tolerated", "#70c070", ""], ' '"42": ["R", 0.0004063, 37, 91060, 0, "missense", ' '"tolerated", "#70c070", ""], "39": ["S", 1.145e-05, 1, ' '87350, 0, "missense", "tolerated", "#70c070", ""], ' '"38": ["K", 1.145e-05, 1, 87356, 0, "missense", ' '"deleterious", "#e30e0e", ""], "34": ["P", 3.734e-05, ' '3, 80334, 0, "missense", "tolerated", "#70c070", ""], ' '"33": ["E", 0.0001375, 11, 79974, 0, "missense", ' '"tolerated", "#70c070", ""], "28": ["K", 1.41e-05, 1, ' '70910, 0, "missense", "deleterious", "#e30e0e", ""], ' '"24": ["V", 1.513e-05, 1, 66074, 0, "missense", ' '"tolerated", "#70c070", ""], "19": ["Y", 1.909e-05, 1, ' '52388, 0, "missense", "deleterious", "#e30e0e", ""], ' '"17": ["F", 2.019e-05, 1, 49526, 0, "missense", ' '"deleterious", "#e30e0e", ""], "16": ["S", 2.19e-05, ' '1, 45672, 0, "missense", "deleterious", "#e30e0e", ' '""], "14": ["R", 0.0001292, 5, 38690, 0, "missense", ' '"deleterious", "#e30e0e", ""], "8": ["E", 3.792e-05, ' '1, 26374, 0, "missense", "deleterious", "#e30e0e", ' '""], "5": ["Q", 4.805e-05, 1, 20812, 0, "missense", ' '"deleterious", "#e30e0e", ""]}', 'natural_mutations_pos_list': '{"53": {"val": 1, "AA": "V "}, "70": {"val": ' '1, "AA": "V "}, "85": {"val": 1, "AA": "R "}, ' '"92": {"val": 1, "AA": "V "}, "94": {"val": 2, ' '"AA": "C G "}, "112": {"val": 1, "AA": "F "}, ' '"113": {"val": 1, "AA": "A "}, "119": {"val": ' '2, "AA": "P C "}, "144": {"val": 1, "AA": "P ' '"}, "147": {"val": 2, "AA": "T L "}, "151": ' '{"val": 1, "AA": "V "}, "163": {"val": 1, ' '"AA": "Q "}, "164": {"val": 1, "AA": "R "}, ' '"167": {"val": 1, "AA": "C "}, "169": {"val": ' '2, "AA": "L V "}, "172": {"val": 2, "AA": "L G ' '"}, "173": {"val": 1, "AA": "T "}, "175": ' '{"val": 1, "AA": "L "}, "176": {"val": 1, ' '"AA": "G "}, "179": {"val": 1, "AA": "F "}, ' '"181": {"val": 2, "AA": "L M "}, "182": ' '{"val": 1, "AA": "C "}, "226": {"val": 2, ' '"AA": "C S "}, "228": {"val": 1, "AA": "F "}, ' '"231": {"val": 2, "AA": "V T "}, "233": ' '{"val": 1, "AA": "T "}, "235": {"val": 1, ' '"AA": "V "}, "236": {"val": 1, "AA": "L "}, ' '"239": {"val": 1, "AA": "F "}, "255": {"val": ' '1, "AA": "T "}, "262": {"val": 1, "AA": "T "}, ' '"264": {"val": 1, "AA": "T "}, "269": {"val": ' '1, "AA": "T "}, "270": {"val": 1, "AA": "R "}, ' '"274": {"val": 1, "AA": "S "}, "279": {"val": ' '1, "AA": "K "}, "280": {"val": 1, "AA": "M "}, ' '"283": {"val": 1, "AA": "H "}, "285": {"val": ' '1, "AA": "I "}, "286": {"val": 1, "AA": "A "}, ' '"290": {"val": 1, "AA": "M "}, "293": {"val": ' '1, "AA": "I "}, "301": {"val": 1, "AA": "K "}, ' '"310": {"val": 2, "AA": "I A "}, "319": ' '{"val": 2, "AA": "M K "}, "320": {"val": 1, ' '"AA": "K "}, "355": {"val": 1, "AA": "Q "}, ' '"365": {"val": 1, "AA": "S "}, "366": {"val": ' '1, "AA": "S "}, "369": {"val": 1, "AA": "F "}, ' '"color": ["#c79494", "#c40100"]}', 'receptor': 'pe2r3_human', 'type': 'protein'} {'hosts': {'arrestin': '', 'gpcr': '', 'gprotein': ''}}

Context processors

django.template.context_processors.csrf: Toggle context
{'csrf_token': <SimpleLazyObject: 'M88WqJPjTs4MZzZzllu9xnDYdE2LTiBU3W0CEfEkWTw4DcTzsCnDKewtZkN8TLuZ'>}
django.contrib.auth.context_processors.auth: Toggle context
{'user': <SimpleLazyObject: <django.contrib.auth.models.AnonymousUser object at 0x7f2e80370128>>, 'perms': <django.contrib.auth.context_processors.PermWrapper object at 0x7f2e80370710>}
django.template.context_processors.debug: Toggle context
{'debug': True, 'sql_queries': <function debug.<locals>.<lambda> at 0x7f2e712b0ae8>}
django.template.context_processors.i18n: Toggle context
{'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')], 'LANGUAGE_CODE': 'en-us', 'LANGUAGE_BIDI': False}
django.template.context_processors.media: Toggle context
{'MEDIA_URL': '/media/'}
django.template.context_processors.static: Toggle context
{'STATIC_URL': '/static/'}
django.template.context_processors.tz: Toggle context
{'TIME_ZONE': 'Europe/Copenhagen'}
django.contrib.messages.context_processors.messages: Toggle context
{'messages': <django.contrib.messages.storage.fallback.FallbackStorage object at 0x7f2e803709b0>, 'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30, 'ERROR': 40}}
protwis.context_processors.current_site: Toggle context
{'current_site': 'gpcr'}
protwis.context_processors.canonical_tag: Toggle context
{'canonical_tag': 'https://gpcrdb.org/mutational_landscape/protein/PE2R3_human/'}
protwis.context_processors.documentation_url: Toggle context
{'documentation_url': 'https://docs.gpcrdb.org/'}
protwis.context_processors.google_analytics: Toggle context
{}
protwis.context_processors.site_title: Toggle context
{'site_title': 'GPCRdb'}

Cache calls from 2 backends

Summary

Total calls	Total time	Cache hits	Cache misses
3	22.566795349121094 ms	2	0

Commands

add	get	set	delete	clear	get_many	set_many	delete_many	has_key	incr	decr	incr_version	decr_version
0	2	0	0	0	0	0	0	1	0	0	0	0

Calls

Time (ms)		Type	Arguments	Keyword arguments	Backend
+	0.5908	has_key	('VARIATION_0288a38cbd0be35b4f49c65d4fa8f14c',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e80370be0>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(122) if not cache_variation.has_key(cache_key) and len(proteins)>0:
+	21.8372	get	('VARIATION_0288a38cbd0be35b4f49c65d4fa8f14c',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e80370be0>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(252) cache_data = cache_variation.get(cache_key)
+	0.1388	get	('citation_urls',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e80370be0>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(292) return render(request, 'browser.html', cache_data) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/shortcuts.py in render(36) content = loader.render_to_string(template_name, context, request, using=using) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/loader.py in render_to_string(62) return template.render(context, request) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/backends/django.py in render(61) return self.template.render(context) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/base.py in render(169) with context.bind_template(self): /usr/lib/python3.6/contextlib.py in __enter__(81) return next(self.gen) /home/protwis/gpcrdb_test/protwis/context_processors.py in canonical_tag(31) citation_dict = cache.get("citation_urls")

Signals

Signal	Providing	Receivers
class_prepared	class
connection_created	connection
got_request_exception	request
post_delete	instance, using
post_init	instance
post_migrate	app_config, plan, interactive, verbosity, apps, using	create_permissions, create_contenttypes
post_save	created, raw, instance, update_fields, using
pre_delete	instance, using
pre_init	instance, args, kwargs
pre_save	instance, using, update_fields, raw
request_finished		close_old_connections, close_caches, reset_urlconf
request_started	environ	reset_queries, close_old_connections

Log messages

No messages logged.

Path	Location
admin/js/cancel.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/cancel.js
admin/js/autocomplete.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/autocomplete.js
admin/js/collapse.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.min.js
admin/js/actions.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.min.js
admin/js/urlify.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/urlify.js
admin/js/popup_response.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/popup_response.js
admin/js/collapse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.js
admin/js/SelectBox.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectBox.js
admin/js/calendar.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/calendar.js
admin/js/actions.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.js
admin/js/prepopulate.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate.min.js
admin/js/SelectFilter2.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectFilter2.js
admin/js/timeparse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/timeparse.js
admin/js/jquery.init.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/jquery.init.js
admin/js/core.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/core.js
admin/js/prepopulate_init.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate_init.js
admin/js/inlines.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/inlines.js
admin/js/inlines.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/inlines.min.js
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