Variation Browser

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Receptor Position GPCRdb Segment Variant Mutation type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
Receptor Position GPCRdb Segment Variant Mutation Type Allele Frequency Allele Count Allele Number Homozygotes SIFT score PolyPhen score Functional annotation
s1pr1_human 283 ECL3 K => Ter stop gained 8.276e-06 1 120838 0 None None
s1pr1_human 3 N-term P => T missense 1.785e-05 2 112034 0 0.17 0.0
s1pr1_human 5 N-term S => G missense 8.763e-06 1 114122 0 0.13 0.0 PTM (O-GalNAc)
s1pr1_human 11 N-term A => D missense 0.00455 539 118470 11 0.23 0.019
s1pr1_human 13 N-term R => G missense 0.01404 1678 119544 17 0.39 0.001
s1pr1_human 13 N-term R => H missense 8.354e-06 1 119704 0 0.08 0.002
s1pr1_human 15 N-term S => L missense 1.661e-05 2 120408 0 0.33 0.001
s1pr1_human 15 N-term S => W missense 1.661e-05 2 120408 0 0.02 0.473
s1pr1_human 20 N-term V => F missense 8.255e-06 1 121134 0 0.66 0.001
s1pr1_human 27 N-term R => Q missense 8.239e-06 1 121370 0 0.51 0.001
s1pr1_human 38 N-term S => G missense 8.237e-06 1 121406 0 0.42 0.0
s1pr1_human 38 N-term S => R missense 8.237e-06 1 121406 0 0.74 0.001
s1pr1_human 39 N-term A => T missense 1.647e-05 2 121406 0 0.61 0.0
s1pr1_human 45 1.32x32 TM1 I => T missense 0.002001 243 121412 6 0.23 0.002
s1pr1_human 51 1.38x38 TM1 V => M missense 8.236e-06 1 121412 0 0.03 0.01
s1pr1_human 54 1.41x41 TM1 L => I missense 8.236e-06 1 121412 0 0.94 0.001
s1pr1_human 61 1.48x48 TM1 L => M missense 8.236e-06 1 121412 0 0.01 0.693
s1pr1_human 64 1.51x51 TM1 I => M missense 3.295e-05 4 121412 0 0.03 0.099
s1pr1_human 79 2.38x38 TM2 P => S missense 8.236e-06 1 121412 0 0.14 0.977
s1pr1_human 81 2.40x40 TM2 Y => C missense 8.236e-06 1 121412 0 0.0 0.998
s1pr1_human 115 3.23x23 TM3 A => T missense 8.238e-06 1 121396 0 0.82 0.013
s1pr1_human 123 3.31x31 TM3 S => C missense 8.237e-06 1 121410 0 0.03 0.275
s1pr1_human 123 3.31x31 TM3 S => R missense 8.237e-06 1 121410 0 0.0 0.908
s1pr1_human 137 3.45x45 TM3 A => S missense 8.237e-06 1 121398 0 0.0 0.999
s1pr1_human 153 34.54x54 ICL2 N => D missense 8.241e-06 1 121348 0 1.0 0.004 GP (contact)
s1pr1_human 157 4.39x39 TM4 N => K missense 8.241e-06 1 121338 0 1.0 0.002
s1pr1_human 166 4.48x48 TM4 A => T missense 8.242e-06 1 121326 0 0.25 0.05
s1pr1_human 172 4.54x54 TM4 L => F missense 8.242e-06 1 121332 0 0.28 0.052
s1pr1_human 180 4.62x62 TM4 M => I missense 8.242e-06 1 121334 0 0.11 0.068
s1pr1_human 185 ECL2 I => V missense 8.242e-06 1 121330 0 0.04 0.007
s1pr1_human 186 ECL2 S => I missense 8.242e-06 1 121328 0 0.05 0.094
s1pr1_human 190 ECL2 S => N missense 8.241e-06 1 121338 0 0.21 0.003
s1pr1_human 198 ECL2 Y => C missense 8.24e-06 1 121352 0 0.0 0.885
s1pr1_human 215 5.52x52 TM5 L => V missense 1.648e-05 2 121350 0 0.36 0.129
s1pr1_human 216 5.53x53 TM5 S => C missense 8.241e-06 1 121342 0 0.0 0.759
s1pr1_human 224 5.61x61 TM5 I => T missense 8.242e-06 1 121334 0 0.0 0.997 GP (contact)
s1pr1_human 224 5.61x61 TM5 I => N missense 8.242e-06 1 121334 0 0.0 0.999 GP (contact)
s1pr1_human 231 5.68x68 TM5 R => W missense 8.245e-06 1 121288 0 0.01 0.983 GP (contact)
s1pr1_human 231 5.68x68 TM5 R => Q missense 8.244e-06 1 121298 0 0.15 0.283 GP (contact)
s1pr1_human 238 ICL3 R => C missense 0.0001732 21 121280 0 0.01 0.93
s1pr1_human 239 ICL3 K => E missense 8.246e-06 1 121278 0 0.23 0.507
s1pr1_human 241 ICL3 I => V missense 2.474e-05 3 121254 0 0.68 0.001
s1pr1_human 243 ICL3 K => R missense 1.65e-05 2 121232 0 0.64 0.005
s1pr1_human 245 6.24x24 TM6 S => G missense 8.249e-06 1 121234 0 0.18 0.099
s1pr1_human 245 6.24x24 TM6 S => N missense 3.3e-05 4 121228 0 0.29 0.005
s1pr1_human 267 6.46x46 TM6 A => T missense 8.264e-06 1 121012 0 0.07 0.432
s1pr1_human 270 6.49x49 TM6 A => V missense 8.266e-06 1 120984 0 0.15 0.043
s1pr1_human 276 6.55x55 TM6 L => F missense 8.269e-06 1 120932 0 0.21 0.866 LB (hydrophobic)
s1pr1_human 293 7.35x34 TM7 A => T missense 8.282e-06 1 120742 0 0.04 0.092
s1pr1_human 307 7.49x49 TM7 N => D missense 8.286e-06 1 120692 0 0.0 1.0 SodiumPocket MicroSwitch
s1pr1_human 309 7.51x51 TM7 I => L missense 8.286e-06 1 120684 0 0.27 0.047
s1pr1_human 314 7.56x56 TM7 T => S missense 0.0002238 27 120650 0 0.4 0.001 GP (contact)
s1pr1_human 323 8.55x55 H8 I => L missense 8.303e-06 1 120440 0 1.0 0.0
s1pr1_human 324 8.56x56 H8 R => Q missense 8.307e-06 1 120384 0 0.01 0.078
s1pr1_human 326 8.58x58 H8 M => T missense 8.312e-06 1 120302 0 0.0 0.005
s1pr1_human 332 C-term P => A missense 8.344e-06 1 119846 0 0.55 0.0
s1pr1_human 332 C-term P => R missense 5.009e-05 6 119778 0 0.39 0.001
s1pr1_human 332 C-term P => Q missense 8.349e-06 1 119778 0 0.33 0.063
s1pr1_human 334 C-term G => R missense 4.181e-05 5 119578 0 0.46 0.001
s1pr1_human 342 C-term R => Q missense 8.426e-06 1 118676 0 0.44 0.006
s1pr1_human 344 C-term I => M missense 8.478e-06 1 117950 0 0.23 0.615
s1pr1_human 346 C-term A => S missense 8.486e-06 1 117842 0 0.83 0.002
s1pr1_human 352 C-term R => G missense 2.569e-05 3 116782 0 0.35 0.023
s1pr1_human 352 C-term R => C missense 8.563e-06 1 116782 0 0.12 0.032
s1pr1_human 358 C-term S => C missense 8.604e-06 1 116220 0 0.01 0.96 PTM (Phosphorylation)
s1pr1_human 365 C-term E => K missense 8.62e-06 1 116014 0 0.24 0.001
s1pr1_human 367 C-term D => G missense 1.724e-05 2 115996 0 0.17 0.002
s1pr1_human 374 C-term S => F missense 8.629e-06 1 115894 0 0.0 0.839
s1pr1_human 378 C-term V => I missense 8.634e-06 1 115818 0 0.69 0.001
s1pr1_human 380 C-term S => Y missense 1.729e-05 2 115664 0 0.02 0.825


Residue

Diagrams

ICL1 K K F H ICL1ECL1 G A T T Y K L ECL1ICL2 M K L H N G S ICL2ECL2 W N C I S A L S S C S T V L P L Y ECL2ICL3 F R K N I S K A ICL3ECL3 K V K T C ECL3N-term M G P T S V P L V K A H R S S V S D Y V N Y D I I V R H Y N Y T G K L N I S A D K N-termC-term C C K C P S G D S A G K F K R P I I A G M E F S R S K S D N S S H P Q K D E G D N P E T I M S S G N V N S S S C-term E N S I K L T S V V F I L I C C F I I L E N I F V L L T I W K T R P M Y Y F I G N L A L S D L L A G V A Y T A N L L L S T P A Q W F L R E G S M F V A L S A S V F S L L A I A I E R Y I T M L K N N F R L F L L I S A C W V I S L I L G G L P I M G H K H Y I L F C T T V F T L L L L S I V I L Y C R I Y S L V R T R S R R L T S R S S E K S L A L L K T V I I V L S V F I A C W A P L F I L L L L D V G C D I L F R A E Y F L V L A V L N S G T N P I I Y T L T N K E F I R M R R A I M S
SnakePlot Download: PNG | SVG I N E L I I F C C I L I F V V S T L K I 1 G N L A L S D L L A G V A Y T A N L L L 2 A L L S F V S A S L A V F M S G E R L F 3 L F L L I S A C W V I S L I L G G L P I 4 Y L I V I S L L L L T F V T T C F L I Y 5 I I V L S V F I A C W A P L F I L L L L 6 I P N T G S N L V A L V L F Y E A R F 7
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Versions

Package Name Version
Django 2.2.1
Python 3.6.7
debug_toolbar Debug Toolbar 1.11
polymorphic Polymorphic 2.0.3
rest_framework Django REST framework 3.9.3
rest_framework_swagger Rest_Framework_Swagger 2.2.0

Time

Resource usage

Resource Value
User CPU time 129.099 msec
System CPU time 3.992 msec
Total CPU time 133.091 msec
Elapsed time 142.496 msec
Context switches 10 voluntary, 5 involuntary

Browser timing

Timing attribute Timeline Milliseconds since navigation start (+length)

Settings from protwis.settings

Setting Value
ABSOLUTE_URL_OVERRIDES {}
ADMINS []
ALLOWED_HOSTS ['*']
APPEND_SLASH True
AUTHENTICATION_BACKENDS ['django.contrib.auth.backends.ModelBackend']
AUTH_PASSWORD_VALIDATORS '********************'
AUTH_USER_MODEL 'auth.User'
BASE_DIR '/home/protwis/gpcrdb_test'
BUILD_CACHE_DIR '/home/protwis/gpcrdb_data/cache'
CACHES {'alignments': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test_alignment', 'OPTIONS': {'MAX_ENTRIES': 1000}}, 'default': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test/', 'OPTIONS': {'MAX_ENTRIES': 10000000}}}
CACHE_MIDDLEWARE_ALIAS 'default'
CACHE_MIDDLEWARE_KEY_PREFIX '********************'
CACHE_MIDDLEWARE_SECONDS 600
CSRF_COOKIE_AGE 31449600
CSRF_COOKIE_DOMAIN None
CSRF_COOKIE_HTTPONLY False
CSRF_COOKIE_NAME 'csrftoken'
CSRF_COOKIE_PATH '/'
CSRF_COOKIE_SAMESITE 'Lax'
CSRF_COOKIE_SECURE False
CSRF_FAILURE_VIEW 'django.views.csrf.csrf_failure'
CSRF_HEADER_NAME 'HTTP_X_CSRFTOKEN'
CSRF_TRUSTED_ORIGINS []
CSRF_USE_SESSIONS False
DATABASES {'default': {'ATOMIC_REQUESTS': False, 'AUTOCOMMIT': True, 'CONN_MAX_AGE': 0, 'ENGINE': 'django.db.backends.postgresql_psycopg2', 'HOST': 'localhost', 'NAME': 'protwis_202107', 'OPTIONS': {}, 'PASSWORD': '********************', 'PORT': '', 'TEST': {'CHARSET': None, 'COLLATION': None, 'MIRROR': None, 'NAME': None}, 'TIME_ZONE': None, 'USER': 'protwis'}}
DATABASE_ROUTERS []
DATA_DIR '/home/protwis/gpcrdb_data'
DATA_UPLOAD_MAX_MEMORY_SIZE 2621440
DATA_UPLOAD_MAX_NUMBER_FIELDS 1000
DATETIME_FORMAT 'N j, Y, P'
DATETIME_INPUT_FORMATS ['%Y-%m-%d %H:%M:%S', '%Y-%m-%d %H:%M:%S.%f', '%Y-%m-%d %H:%M', '%Y-%m-%d', '%m/%d/%Y %H:%M:%S', '%m/%d/%Y %H:%M:%S.%f', '%m/%d/%Y %H:%M', '%m/%d/%Y', '%m/%d/%y %H:%M:%S', '%m/%d/%y %H:%M:%S.%f', '%m/%d/%y %H:%M', '%m/%d/%y']
DATE_FORMAT 'N j, Y'
DATE_INPUT_FORMATS ['%Y-%m-%d', '%m/%d/%Y', '%m/%d/%y', '%b %d %Y', '%b %d, %Y', '%d %b %Y', '%d %b, %Y', '%B %d %Y', '%B %d, %Y', '%d %B %Y', '%d %B, %Y']
DEBUG True
DEBUG_PROPAGATE_EXCEPTIONS False
DEBUG_TOOLBAR_PATCH_SETTINGS False
DECIMAL_SEPARATOR '.'
DEFAULT_CHARSET 'utf-8'
DEFAULT_CONTENT_TYPE 'text/html'
DEFAULT_EXCEPTION_REPORTER_FILTER 'django.views.debug.SafeExceptionReporterFilter'
DEFAULT_FILE_STORAGE 'django.core.files.storage.FileSystemStorage'
DEFAULT_FROM_EMAIL 'webmaster@localhost'
DEFAULT_INDEX_TABLESPACE ''
DEFAULT_NUMBERING_SCHEME 'gpcrdb'
DEFAULT_PROTEIN_STATE 'inactive'
DEFAULT_SITE 'gpcr'
DEFAULT_TABLESPACE ''
DISALLOWED_USER_AGENTS []
DOCUMENTATION_URL 'https://docs.gpcrdb.org/'
EMAIL_BACKEND 'django.core.mail.backends.smtp.EmailBackend'
EMAIL_HOST 'localhost'
EMAIL_HOST_PASSWORD '********************'
EMAIL_HOST_USER ''
EMAIL_PORT 25
EMAIL_SSL_CERTFILE None
EMAIL_SSL_KEYFILE '********************'
EMAIL_SUBJECT_PREFIX '[Django] '
EMAIL_TIMEOUT None
EMAIL_USE_LOCALTIME False
EMAIL_USE_SSL False
EMAIL_USE_TLS False
FILE_CHARSET 'utf-8'
FILE_UPLOAD_DIRECTORY_PERMISSIONS None
FILE_UPLOAD_HANDLERS ['django.core.files.uploadhandler.MemoryFileUploadHandler', 'django.core.files.uploadhandler.TemporaryFileUploadHandler']
FILE_UPLOAD_MAX_MEMORY_SIZE 2621440
FILE_UPLOAD_PERMISSIONS None
FILE_UPLOAD_TEMP_DIR None
FIRST_DAY_OF_WEEK 0
FIXTURE_DIRS []
FORCE_SCRIPT_NAME None
FORMAT_MODULE_PATH None
FORM_RENDERER 'django.forms.renderers.DjangoTemplates'
GOOGLE_ANALYTICS_API '********************'
GOOGLE_ANALYTICS_KEY '********************'
IGNORABLE_404_URLS []
INSTALLED_APPS ('django.contrib.admin', 'django.contrib.auth', 'django.contrib.contenttypes', 'django.contrib.sessions', 'django.contrib.messages', 'django.contrib.staticfiles', 'django.contrib.humanize', 'debug_toolbar', 'rest_framework', 'rest_framework_swagger', 'polymorphic', 'common', 'api', 'news', 'pages', 'home', 'protein', 'family', 'residue', 'alignment', 'similaritysearch', 'similaritymatrix', 'structure', 'ligand', 'interaction', 'mutation', 'phylogenetic_trees', 'sitesearch', 'build_gpcr', 'construct', 'tools', 'drugs', 'signprot', 'signprot2', 'mutational_landscape', 'contactnetwork', 'seqsign', 'angles', 'hotspots')
INTERNAL_IPS '10.0.2.2'
LANGUAGES [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')]
LANGUAGES_BIDI ['he', 'ar', 'fa', 'ur']
LANGUAGE_CODE 'en-us'
LANGUAGE_COOKIE_AGE None
LANGUAGE_COOKIE_DOMAIN None
LANGUAGE_COOKIE_NAME 'django_language'
LANGUAGE_COOKIE_PATH '/'
LOCALE_PATHS []
LOGGING {'disable_existing_loggers': False, 'formatters': {'verbose': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s] %(message)s'}, 'verbose_low': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s]'}}, 'handlers': {'build': {'class': 'logging.FileHandler', 'filename': 'logs/build.log', 'formatter': 'verbose', 'level': 'DEBUG'}, 'django': {'class': 'logging.FileHandler', 'filename': 'logs/django.log', 'formatter': 'verbose', 'level': 'WARNING'}, 'protwis': {'class': 'logging.FileHandler', 'filename': 'logs/protwis.log', 'formatter': 'verbose', 'level': 'DEBUG'}}, 'loggers': {'build': {'handlers': ['build'], 'level': 'DEBUG'}, 'django': {'handlers': ['django'], 'level': 'WARNING', 'propagate': True}, 'protwis': {'handlers': ['protwis'], 'level': 'DEBUG'}}, 'version': 1}
LOGGING_CONFIG 'logging.config.dictConfig'
LOGIN_REDIRECT_URL '/accounts/profile/'
LOGIN_URL '/accounts/login/'
LOGOUT_REDIRECT_URL None
MANAGERS []
MEDIA_ROOT '/protwis/media/protwis'
MEDIA_URL '/media/'
MESSAGE_STORAGE 'django.contrib.messages.storage.fallback.FallbackStorage'
MIDDLEWARE ('common.middleware.stats.StatsMiddleware', 'debug_toolbar.middleware.DebugToolbarMiddleware', 'django.contrib.sessions.middleware.SessionMiddleware', 'django.middleware.common.CommonMiddleware', 'django.middleware.csrf.CsrfViewMiddleware', 'django.contrib.auth.middleware.AuthenticationMiddleware', 'django.contrib.messages.middleware.MessageMiddleware', 'django.middleware.clickjacking.XFrameOptionsMiddleware')
MIGRATION_MODULES {}
MONTH_DAY_FORMAT 'F j'
NUMBER_GROUPING 0
PASSWORD_HASHERS '********************'
PASSWORD_RESET_TIMEOUT_DAYS '********************'
PREPEND_WWW False
REFERENCE_POSITIONS {'D1S1': 'D1S1x50', 'D1S2': 'D1S2x50', 'D1T1': 'D1T1x50', 'D1e1': 'D1e1x50', 'ECL1': '23x50', 'ECL2': '45x50', 'H8': '8x50', 'ICL1': '12x50', 'ICL2': '34x50', 'TM1': '1x50', 'TM2': '2x50', 'TM3': '3x50', 'TM4': '4x50', 'TM5': '5x50', 'TM6': '6x50', 'TM7': '7x50'}
ROOT_URLCONF 'protwis.urls'
SECRET_KEY '********************'
SECURE_BROWSER_XSS_FILTER False
SECURE_CONTENT_TYPE_NOSNIFF False
SECURE_HSTS_INCLUDE_SUBDOMAINS False
SECURE_HSTS_PRELOAD False
SECURE_HSTS_SECONDS 0
SECURE_PROXY_SSL_HEADER None
SECURE_REDIRECT_EXEMPT []
SECURE_SSL_HOST None
SECURE_SSL_REDIRECT False
SERVER_EMAIL 'root@localhost'
SESSION_CACHE_ALIAS 'default'
SESSION_COOKIE_AGE 86400
SESSION_COOKIE_DOMAIN None
SESSION_COOKIE_HTTPONLY True
SESSION_COOKIE_NAME 'sessionid'
SESSION_COOKIE_PATH '/'
SESSION_COOKIE_SAMESITE 'Lax'
SESSION_COOKIE_SECURE False
SESSION_ENGINE 'django.contrib.sessions.backends.db'
SESSION_EXPIRE_AT_BROWSER_CLOSE False
SESSION_FILE_PATH None
SESSION_SAVE_EVERY_REQUEST False
SESSION_SERIALIZER 'django.contrib.sessions.serializers.PickleSerializer'
SETTINGS_MODULE 'protwis.settings'
SHORT_DATETIME_FORMAT 'm/d/Y P'
SHORT_DATE_FORMAT 'm/d/Y'
SIGNING_BACKEND 'django.core.signing.TimestampSigner'
SILENCED_SYSTEM_CHECKS []
SITE_NAME 'gpcr'
SITE_TITLE 'GPCRdb'
STATICFILES_DIRS ('/home/protwis/gpcrdb_test/static',)
STATICFILES_FINDERS ['django.contrib.staticfiles.finders.FileSystemFinder', 'django.contrib.staticfiles.finders.AppDirectoriesFinder']
STATICFILES_STORAGE 'django.contrib.staticfiles.storage.StaticFilesStorage'
STATIC_ROOT '/home/protwis/static_test/'
STATIC_URL '/static/'
SWAGGER_SETTINGS {'USE_SESSION_AUTH': False}
TEMPLATES [{'APP_DIRS': True, 'BACKEND': 'django.template.backends.django.DjangoTemplates', 'DIRS': [], 'OPTIONS': {'context_processors': ['django.contrib.auth.context_processors.auth', 'django.template.context_processors.debug', 'django.template.context_processors.i18n', 'django.template.context_processors.media', 'django.template.context_processors.static', 'django.template.context_processors.tz', 'django.contrib.messages.context_processors.messages', 'protwis.context_processors.current_site', 'protwis.context_processors.canonical_tag', 'protwis.context_processors.documentation_url', 'protwis.context_processors.google_analytics', 'protwis.context_processors.site_title'], 'debug': True}}]
TEST_NON_SERIALIZED_APPS []
TEST_RUNNER 'django.test.runner.DiscoverRunner'
THOUSAND_SEPARATOR ','
TIME_FORMAT 'P'
TIME_INPUT_FORMATS ['%H:%M:%S', '%H:%M:%S.%f', '%H:%M']
TIME_ZONE 'Europe/Copenhagen'
USE_I18N True
USE_L10N True
USE_THOUSAND_SEPARATOR False
USE_TZ True
USE_X_FORWARDED_HOST False
USE_X_FORWARDED_PORT False
WSGI_APPLICATION None
X_FRAME_OPTIONS 'SAMEORIGIN'
YEAR_MONTH_FORMAT 'F Y'

Headers

Request headers

Key Value
Accept text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8
Accept-Encoding br,gzip
Accept-Language en-US,en;q=0.5
Connection close
Host test.gpcrdb.org
User-Agent CCBot/2.0 (https://commoncrawl.org/faq/)
X-Forwarded-For 3.235.186.94
X-Forwarded-Proto https
X-Real-Ip 3.235.186.94

Response headers

Key Value
Content-Length 467896
Content-Type text/html; charset=utf-8
Vary Cookie
X-Frame-Options SAMEORIGIN

WSGI environ

Since the WSGI environ inherits the environment of the server, only a significant subset is shown below.

Key Value
PATH_INFO /mutational_landscape/protein/S1PR1_human/
QUERY_STRING
REMOTE_ADDR
REQUEST_METHOD GET
SCRIPT_NAME
SERVER_NAME test.gpcrdb.org
SERVER_PORT 443
SERVER_PROTOCOL HTTP/1.0
SERVER_SOFTWARE gunicorn/19.9.0

Request

View information

View function Arguments Keyword arguments URL name
mutational_landscape.views.render_variants () {'protein': 'S1PR1_human'} render

No cookies

No session data

No GET data

No POST data

SQL queries from 1 connection

  •   default 2.62 ms (1 query )
  Query Timeline Time (ms) Action
  +
SELECT ••• "protein"."id", "protein"."parent_id", "protein"."family_id", "protein"."species_id", "protein"."source_id", "protein"."residue_numbering_scheme_id", "protein"."sequence_type_id", "protein"."entry_name", "protein"."accession", "protein"."name", "protein"."sequence" FROM "protein" WHERE "protein"."entry_name" = 's1pr1_human'
100.0%
2.62

Connection: default

/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(89)
  proteins.append(Protein.objects.get(entry_name=protein.lower()))

Static files (590 found, 40 used)

Static file path

  1. /home/protwis/gpcrdb_test/static

Static file apps

  1. django.contrib.admin
  2. debug_toolbar
  3. rest_framework
  4. rest_framework_swagger
  5. polymorphic

Static files

bootstrap/css/bootstrap.min.css
/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-submenu.min.css
/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
home/css/jquery-ui.min.css
/home/protwis/gpcrdb_test/static/home/css/jquery-ui.min.css
home/css/jquery-ui.theme.min.css
/home/protwis/gpcrdb_test/static/home/css/jquery-ui.theme.min.css
home/css/bootstrap-treeview.min.css
/home/protwis/gpcrdb_test/static/home/css/bootstrap-treeview.min.css
home/css/style.css
/home/protwis/gpcrdb_test/static/home/css/style.css
flowplayer/flowplayer.css
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
home/css/cookieconsent.min.css
/home/protwis/gpcrdb_test/static/home/css/cookieconsent.min.css
home/css/jquery.dataTables.min.css
/home/protwis/gpcrdb_test/static/home/css/jquery.dataTables.min.css
home/css/structure_browser.css
/home/protwis/gpcrdb_test/static/home/css/structure_browser.css
home/css/residue_table.css
/home/protwis/gpcrdb_test/static/home/css/residue_table.css
home/css/alignment.css
/home/protwis/gpcrdb_test/static/home/css/alignment.css
/home/protwis/gpcrdb_test/static
home/css/mainmenu.css
/home/protwis/gpcrdb_test/static/home/css/mainmenu.css
home/css/modal.css
/home/protwis/gpcrdb_test/static/home/css/modal.css
home/css/jquery.powertip.css
/home/protwis/gpcrdb_test/static/home/css/jquery.powertip.css
home/js/jquery-3.1.1.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/citation_tool.js
/home/protwis/gpcrdb_test/static/home/js/citation_tool.js
home/js/joinus_tool.js
/home/protwis/gpcrdb_test/static/home/js/joinus_tool.js
home/js/jquery-3.1.1.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery-3.1.1.min.js
home/js/jquery-ui.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery-ui.min.js
bootstrap/js/bootstrap.min.js
/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/js/bootstrap-submenu.js
/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
home/js/navbar-autocomplete.js
/home/protwis/gpcrdb_test/static/home/js/navbar-autocomplete.js
home/js/svg-pan-zoom.min.js
/home/protwis/gpcrdb_test/static/home/js/svg-pan-zoom.min.js
home/js/bootstrap-treeview.min.js
/home/protwis/gpcrdb_test/static/home/js/bootstrap-treeview.min.js
home/js/papaparse.min.js
/home/protwis/gpcrdb_test/static/home/js/papaparse.min.js
flowplayer/flowplayer.min.js
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.min.js
flowplayer/flowplayer.overlay.min.js
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.min.js
flowplayer/flowplayer.overlay.bootstrap.js
/home/protwis/gpcrdb_test/static/flowplayer/flowplayer.overlay.bootstrap.js
home/js/gpcrdb.js
/home/protwis/gpcrdb_test/static/home/js/gpcrdb.js
home/js/cookieconsent.min.js
/home/protwis/gpcrdb_test/static/home/js/cookieconsent.min.js
home/js/jquery.dataTables.min.js
/home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.min.js
home/js/dataTables.tableTools.min.js
/home/protwis/gpcrdb_test/static/home/js/dataTables.tableTools.min.js
home/js/jquery.dataTables.columnFilter.js
/home/protwis/gpcrdb_test/static/home/js/jquery.dataTables.columnFilter.js
home/js/selection.js
/home/protwis/gpcrdb_test/static/home/js/selection.js
home/js/saveSvgAsPng.js
/home/protwis/gpcrdb_test/static/home/js/saveSvgAsPng.js
home/js/alignment.js
/home/protwis/gpcrdb_test/static/home/js/alignment.js
home/js/diagrams.js
/home/protwis/gpcrdb_test/static/home/js/diagrams.js
home/js/residuetable.js
/home/protwis/gpcrdb_test/static/home/js/residuetable.js

django.contrib.staticfiles.finders.FileSystemFinder (415 files)

Path Location
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visualization_scripts/pymol_view_generic_numbers.pml /home/protwis/gpcrdb_test/static/visualization_scripts/pymol_view_generic_numbers.pml
bootstrap/js/npm.js /home/protwis/gpcrdb_test/static/bootstrap/js/npm.js
bootstrap/js/bootstrap.js /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.js
bootstrap/js/bootstrap-submenu.js /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
bootstrap/js/bootstrap.min.js /home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
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blast/protwis_blastdb.psd /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psd
blast/protwis_blastdb.phr /home/protwis/gpcrdb_test/static/blast/protwis_blastdb.phr
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blast/protwis_human_gpcr_blastdb.phr /home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.phr
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blast/.gitignore /home/protwis/gpcrdb_test/static/blast/.gitignore
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flowplayer/flowplayer.css /home/protwis/gpcrdb_test/static/flowplayer/flowplayer.css
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django.contrib.staticfiles.finders.AppDirectoriesFinder (175 files)

Path Location
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Templates (9 rendered)

Template paths

None

Templates

browser.html
/home/protwis/gpcrdb_test/mutational_landscape/templates/browser.html
Toggle context {'False': False, 'None': None, 'True': True} {'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'ERROR': 40, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30}, 'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), 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('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')], 'LANGUAGE_BIDI': False, 'LANGUAGE_CODE': 'en-us', 'MEDIA_URL': '/media/', 'STATIC_URL': '/static/', 'TIME_ZONE': 'Europe/Copenhagen', 'canonical_tag': 'https://gpcrdb.org/mutational_landscape/protein/S1PR1_human/', 'csrf_token': <SimpleLazyObject: '3wDDTJtBLhnmWORNjJLHOC0wVsi6ey8Ly9Yd9Vxgngd4WyjcReQ7l9n4qnXh31Ez'>, 'current_site': 'gpcr', 'debug': True, 'documentation_url': 'https://docs.gpcrdb.org/', 'messages': <django.contrib.messages.storage.fallback.FallbackStorage object at 0x7f2e702ee278>, 'perms': <django.contrib.auth.context_processors.PermWrapper object at 0x7f2e710b5b00>, 'site_title': 'GPCRdb', 'sql_queries': <function debug.<locals>.<lambda> at 0x7f2e6f1ca840>, 'user': <SimpleLazyObject: <django.contrib.auth.models.AnonymousUser object at 0x7f2e89ed9438>>} {'HelixBox': <common.diagrams_gpcr.DrawHelixBox object at 0x7f2e72f481d0>, 'SnakePlot': <common.diagrams_gpcr.DrawSnakePlot 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home/base.html
/home/protwis/gpcrdb_test/home/templates/home/base.html
Toggle context {'False': False, 'None': None, 'True': True} {'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'ERROR': 40, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30}, 'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), 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home/mainmenu.html
/home/protwis/gpcrdb_test/home/templates/home/mainmenu.html
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home/common.html
/home/protwis/gpcrdb_test/home/templates/home/common.html
Toggle context {'False': False, 'None': None, 'True': True} {'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'ERROR': 40, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30}, 'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), 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home/gpcrdb.html
/home/protwis/gpcrdb_test/home/templates/home/gpcrdb.html
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home/gproteindb.html
/home/protwis/gpcrdb_test/home/templates/home/gproteindb.html
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home/arrestindb.html
/home/protwis/gpcrdb_test/home/templates/home/arrestindb.html
Toggle context {'False': False, 'None': None, 'True': True} {'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'ERROR': 40, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30}, 'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), 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home/cite_and_join_us.html
/home/protwis/gpcrdb_test/home/templates/home/cite_and_join_us.html
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["T", ' '8.242e-06, 1, 121326, 0, "missense", "tolerated", ' '"#70c070", ""], "172": ["F", 8.242e-06, 1, 121332, 0, ' '"missense", "tolerated", "#70c070", ""], "180": ["I", ' '8.242e-06, 1, 121334, 0, "missense", "tolerated", ' '"#70c070", ""], "185": ["V", 8.242e-06, 1, 121330, 0, ' '"missense", "deleterious", "#e30e0e", ""], "186": ' '["I", 8.242e-06, 1, 121328, 0, "missense", ' '"deleterious", "#e30e0e", ""], "190": ["N", 8.241e-06, ' '1, 121338, 0, "missense", "tolerated", "#70c070", ""], ' '"198": ["C", 8.24e-06, 1, 121352, 0, "missense", ' '"deleterious", "#e30e0e", ""], "215": ["V", 1.648e-05, ' '2, 121350, 0, "missense", "deleterious", "#e30e0e", ' '""], "216": ["C", 8.241e-06, 1, 121342, 0, "missense", ' '"deleterious", "#e30e0e", ""], "224": ["N", 8.242e-06, ' '1, 121334, 0, "missense", "deleterious", "#e30e0e", ' '"GP (contact) "], "231": ["Q", 8.244e-06, 1, 121298, ' '0, "missense", "deleterious", "#e30e0e", "GP (contact) ' '"], "238": ["C", 0.0001732, 21, 121280, 0, 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1.724e-05, ' '2, 115996, 0, "missense", "tolerated", "#70c070", ""], ' '"374": ["F", 8.629e-06, 1, 115894, 0, "missense", ' '"deleterious", "#e30e0e", ""], "378": ["I", 8.634e-06, ' '1, 115818, 0, "missense", "tolerated", "#70c070", ""], ' '"380": ["Y", 1.729e-05, 2, 115664, 0, "missense", ' '"deleterious", "#e30e0e", ""]}', 'natural_mutations_pos_list': '{"45": {"val": 1, "AA": "T "}, "51": {"val": ' '1, "AA": "M "}, "54": {"val": 1, "AA": "I "}, ' '"61": {"val": 1, "AA": "M "}, "64": {"val": 1, ' '"AA": "M "}, "79": {"val": 1, "AA": "S "}, ' '"81": {"val": 1, "AA": "C "}, "115": {"val": ' '1, "AA": "T "}, "123": {"val": 2, "AA": "C R ' '"}, "137": {"val": 1, "AA": "S "}, "153": ' '{"val": 1, "AA": "D "}, "157": {"val": 1, ' '"AA": "K "}, "166": {"val": 1, "AA": "T "}, ' '"172": {"val": 1, "AA": "F "}, "180": {"val": ' '1, "AA": "I "}, "215": {"val": 1, "AA": "V "}, ' '"216": {"val": 1, "AA": "C "}, "224": {"val": ' '2, "AA": "T N "}, "231": {"val": 2, "AA": "W Q ' '"}, "245": {"val": 2, "AA": "G N "}, "267": ' '{"val": 1, "AA": "T "}, "270": {"val": 1, ' '"AA": "V "}, "276": {"val": 1, "AA": "F "}, ' '"293": {"val": 1, "AA": "T "}, "307": {"val": ' '1, "AA": "D "}, "309": {"val": 1, "AA": "L "}, ' '"314": {"val": 1, "AA": "S "}, "323": {"val": ' '1, "AA": "L "}, "324": {"val": 1, "AA": "Q "}, ' '"326": {"val": 1, "AA": "T "}, "color": ' '["#c79494", "#c40100"]}', 'receptor': 's1pr1_human', 'type': 'protein'} {'hosts': {'arrestin': '', 'gpcr': '', 'gprotein': ''}}
home/cite_widget_and_modal.html
/home/protwis/gpcrdb_test/home/templates/home/cite_widget_and_modal.html
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('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')], 'LANGUAGE_BIDI': False, 'LANGUAGE_CODE': 'en-us', 'MEDIA_URL': '/media/', 'STATIC_URL': '/static/', 'TIME_ZONE': 'Europe/Copenhagen', 'canonical_tag': 'https://gpcrdb.org/mutational_landscape/protein/S1PR1_human/', 'csrf_token': <SimpleLazyObject: '3wDDTJtBLhnmWORNjJLHOC0wVsi6ey8Ly9Yd9Vxgngd4WyjcReQ7l9n4qnXh31Ez'>, 'current_site': 'gpcr', 'debug': True, 'documentation_url': 'https://docs.gpcrdb.org/', 'messages': <django.contrib.messages.storage.fallback.FallbackStorage object at 0x7f2e702ee278>, 'perms': <django.contrib.auth.context_processors.PermWrapper object at 0x7f2e710b5b00>, 'site_title': 'GPCRdb', 'sql_queries': <function debug.<locals>.<lambda> at 0x7f2e6f1ca840>, 'user': <SimpleLazyObject: <django.contrib.auth.models.AnonymousUser object at 0x7f2e89ed9438>>} {'HelixBox': <common.diagrams_gpcr.DrawHelixBox object at 0x7f2e72f481d0>, 'SnakePlot': <common.diagrams_gpcr.DrawSnakePlot 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["T", ' '8.242e-06, 1, 121326, 0, "missense", "tolerated", ' '"#70c070", ""], "172": ["F", 8.242e-06, 1, 121332, 0, ' '"missense", "tolerated", "#70c070", ""], "180": ["I", ' '8.242e-06, 1, 121334, 0, "missense", "tolerated", ' '"#70c070", ""], "185": ["V", 8.242e-06, 1, 121330, 0, ' '"missense", "deleterious", "#e30e0e", ""], "186": ' '["I", 8.242e-06, 1, 121328, 0, "missense", ' '"deleterious", "#e30e0e", ""], "190": ["N", 8.241e-06, ' '1, 121338, 0, "missense", "tolerated", "#70c070", ""], ' '"198": ["C", 8.24e-06, 1, 121352, 0, "missense", ' '"deleterious", "#e30e0e", ""], "215": ["V", 1.648e-05, ' '2, 121350, 0, "missense", "deleterious", "#e30e0e", ' '""], "216": ["C", 8.241e-06, 1, 121342, 0, "missense", ' '"deleterious", "#e30e0e", ""], "224": ["N", 8.242e-06, ' '1, 121334, 0, "missense", "deleterious", "#e30e0e", ' '"GP (contact) "], "231": ["Q", 8.244e-06, 1, 121298, ' '0, "missense", "deleterious", "#e30e0e", "GP (contact) ' '"], "238": ["C", 0.0001732, 21, 121280, 0, 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"#70c070", "GP ' '(contact) "], "323": ["L", 8.303e-06, 1, 120440, 0, ' '"missense", "tolerated", "#70c070", ""], "324": ["Q", ' '8.307e-06, 1, 120384, 0, "missense", "deleterious", ' '"#e30e0e", ""], "326": ["T", 8.312e-06, 1, 120302, 0, ' '"missense", "deleterious", "#e30e0e", ""], "332": ' '["Q", 8.349e-06, 1, 119778, 0, "missense", ' '"tolerated", "#70c070", ""], "334": ["R", 4.181e-05, ' '5, 119578, 0, "missense", "tolerated", "#70c070", ""], ' '"342": ["Q", 8.426e-06, 1, 118676, 0, "missense", ' '"tolerated", "#70c070", ""], "344": ["M", 8.478e-06, ' '1, 117950, 0, "missense", "deleterious", "#e30e0e", ' '""], "346": ["S", 8.486e-06, 1, 117842, 0, "missense", ' '"tolerated", "#70c070", ""], "352": ["C", 8.563e-06, ' '1, 116782, 0, "missense", "tolerated", "#70c070", ""], ' '"358": ["C", 8.604e-06, 1, 116220, 0, "missense", ' '"deleterious", "#e30e0e", "PTM (Phosphorylation) "], ' '"365": ["K", 8.62e-06, 1, 116014, 0, "missense", ' '"tolerated", "#70c070", ""], "367": ["G", 1.724e-05, ' '2, 115996, 0, "missense", "tolerated", "#70c070", ""], ' '"374": ["F", 8.629e-06, 1, 115894, 0, "missense", ' '"deleterious", "#e30e0e", ""], "378": ["I", 8.634e-06, ' '1, 115818, 0, "missense", "tolerated", "#70c070", ""], ' '"380": ["Y", 1.729e-05, 2, 115664, 0, "missense", ' '"deleterious", "#e30e0e", ""]}', 'natural_mutations_pos_list': '{"45": {"val": 1, "AA": "T "}, "51": {"val": ' '1, "AA": "M "}, "54": {"val": 1, "AA": "I "}, ' '"61": {"val": 1, "AA": "M "}, "64": {"val": 1, ' '"AA": "M "}, "79": {"val": 1, "AA": "S "}, ' '"81": {"val": 1, "AA": "C "}, "115": {"val": ' '1, "AA": "T "}, "123": {"val": 2, "AA": "C R ' '"}, "137": {"val": 1, "AA": "S "}, "153": ' '{"val": 1, "AA": "D "}, "157": {"val": 1, ' '"AA": "K "}, "166": {"val": 1, "AA": "T "}, ' '"172": {"val": 1, "AA": "F "}, "180": {"val": ' '1, "AA": "I "}, "215": {"val": 1, "AA": "V "}, ' '"216": {"val": 1, "AA": "C "}, "224": {"val": ' '2, "AA": "T N "}, "231": {"val": 2, "AA": "W Q ' '"}, "245": {"val": 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Context processors

django.template.context_processors.csrf
Toggle context {'csrf_token': <SimpleLazyObject: '3wDDTJtBLhnmWORNjJLHOC0wVsi6ey8Ly9Yd9Vxgngd4WyjcReQ7l9n4qnXh31Ez'>}
django.contrib.auth.context_processors.auth
Toggle context {'user': <SimpleLazyObject: <django.contrib.auth.models.AnonymousUser object at 0x7f2e89ed9438>>, 'perms': <django.contrib.auth.context_processors.PermWrapper object at 0x7f2e710b5b00>}
django.template.context_processors.debug
Toggle context {'debug': True, 'sql_queries': <function debug.<locals>.<lambda> at 0x7f2e6f1ca840>}
django.template.context_processors.i18n
Toggle context {'LANGUAGES': [('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')], 'LANGUAGE_CODE': 'en-us', 'LANGUAGE_BIDI': False}
django.template.context_processors.media
Toggle context {'MEDIA_URL': '/media/'}
django.template.context_processors.static
Toggle context {'STATIC_URL': '/static/'}
django.template.context_processors.tz
Toggle context {'TIME_ZONE': 'Europe/Copenhagen'}
django.contrib.messages.context_processors.messages
Toggle context {'messages': <django.contrib.messages.storage.fallback.FallbackStorage object at 0x7f2e702ee278>, 'DEFAULT_MESSAGE_LEVELS': {'DEBUG': 10, 'INFO': 20, 'SUCCESS': 25, 'WARNING': 30, 'ERROR': 40}}
protwis.context_processors.current_site
Toggle context {'current_site': 'gpcr'}
protwis.context_processors.canonical_tag
Toggle context {'canonical_tag': 'https://gpcrdb.org/mutational_landscape/protein/S1PR1_human/'}
protwis.context_processors.documentation_url
Toggle context {'documentation_url': 'https://docs.gpcrdb.org/'}
protwis.context_processors.google_analytics
Toggle context {}
protwis.context_processors.site_title
Toggle context {'site_title': 'GPCRdb'}

Cache calls from 2 backends

Summary

Total calls Total time Cache hits Cache misses
3 20.53356170654297 ms 2 0

Commands

add get set delete clear get_many set_many delete_many has_key incr decr incr_version decr_version
0 2 0 0 0 0 0 0 1 0 0 0 0

Calls

Time (ms) Type Arguments Keyword arguments Backend
+ 0.7226 has_key ('VARIATION_390d604e98ea6ce18f4415d8d7aba0ea',) {} <django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e702dbbe0>
/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(122)
  if not cache_variation.has_key(cache_key) and len(proteins)>0:
+ 19.6710 get ('VARIATION_390d604e98ea6ce18f4415d8d7aba0ea',) {} <django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e702dbbe0>
/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(252)
  cache_data = cache_variation.get(cache_key)
+ 0.1400 get ('citation_urls',) {} <django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e702dbbe0>
/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69)
  work_item.run()
/usr/lib/python3.6/concurrent/futures/thread.py in run(56)
  result = self.fn(*self.args, **self.kwargs)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279)
  keepalive = self.handle_request(req, conn)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328)
  respiter = self.wsgi(environ, resp.start_response)
/home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34)
  response = self.get_response(request)
/home/protwis/gpcrdb_test/mutational_landscape/views.py in render_variants(292)
  return render(request, 'browser.html', cache_data)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/shortcuts.py in render(36)
  content = loader.render_to_string(template_name, context, request, using=using)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/loader.py in render_to_string(62)
  return template.render(context, request)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/backends/django.py in render(61)
  return self.template.render(context)
/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/template/base.py in render(169)
  with context.bind_template(self):
/usr/lib/python3.6/contextlib.py in __enter__(81)
  return next(self.gen)
/home/protwis/gpcrdb_test/protwis/context_processors.py in canonical_tag(31)
  citation_dict = cache.get("citation_urls")

Signals

Signal Providing Receivers
class_prepared class
connection_created connection
got_request_exception request
post_delete instance, using
post_init instance
post_migrate app_config, plan, interactive, verbosity, apps, using create_permissions, create_contenttypes
post_save created, raw, instance, update_fields, using
pre_delete instance, using
pre_init instance, args, kwargs
pre_save instance, using, update_fields, raw
request_finished close_old_connections, close_caches, reset_urlconf
request_started environ reset_queries, close_old_connections

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