Residue number
Sequence-based ()
Structure-based (GPCRdb)
[Green monkey] G protein subunit alpha 12
[Bovine] G protein subunit alpha 12
[Duckbill platypus] G protein subunit alpha 12
[Gray short-tailed opossum] G protein subunit alpha 12
[Horse] G protein subunit alpha 12
[White-tufted-ear marmoset] G protein subunit alpha 12
[Rabbit] G protein subunit alpha 12
[Western lowland gorilla] G protein subunit alpha 12
[African elephant] G protein subunit alpha 12
[Rhesus macaque] Uncharacterized protein
[Human] subunit alpha-12
[Mouse] subunit alpha-12
[Rat] subunit alpha-12
[Small-eared galago] G protein subunit alpha 12
[Sumatran orangutan] G protein subunit alpha 12
[Chimpanzee] G protein subunit alpha 12
[Thirteen-lined ground squirrel] G protein subunit alpha 12
[Dog] G protein subunit alpha 12
[European domestic ferret] G protein subunit alpha 12
Residue number
Sequence-based ()
Structure-based (GPCRdb)
Seq consensus
Prop consensus
Length
RESIDUE PROPERTIES & LENGTH
Hydrophobic HY any
Hydrophobic HY 4-5
Hydrophobic aliphatic HA any
Hydrophobic aliphatic HA 1-2
Hydrophobic aliphatic HA 2-3
Hydrophobic aliphatic HA 3
Hydrophobic aliphatic HA 3-4
Hydrophobic aliphatic [M] M 4
Hydrophob al / α-H prop - very high [A] A 1
Hydrophobic aliphatic [I] I
Hydrophobic aliphatic [L] L
Hydrophobic aliphatic [V] V
Hydrophobic aromatic HR any
Hydrophobic aromatic HR 4-5
Hydrophobic aromatic HR 5
Hydrophobic aromatic HR 5-6
Hydrophobic aromatic [W] W 6
Hydropob ar / H-bonding [Y] Y
Hydrophobic aromatic [F] F
Hydrogen bonding (polar) Hb any
Hydrogen bonding Hb 2
Hydrogen bonding Hb 3
Hydrogen bonding [N] N
Hydrogen bonding [Q] Q
Hydrogen bonding [S] S
Hydrogen bonding [T] T
Hydrogen bonding uncharged Hu 2-3
Hydrogen bonding uncharged Hu 3-4
Hydrogen bond acceptor Ha 2-3
Hydrogen bond acceptor Ha 3
Hydrogen bond acceptor Ha 3-4
Hydrogen bond acceptor Ha 4
Hydrogen bond donor Hd 4
Hydrogen bond donor Hd 4-5
Hydrogen bond donor Hd 5-6
Hydrogen bond donor Hd 6
Charged +- any
Charged +- 3-4
Charged +- 4-5
Charged positive + any
Charged pos / H bond / Hphob ar [H] H 4
Charged positive + 4-5
Charged positive [K] K 5
Charged positive + 5-6
Charged positive [R] R 6
Charged negative - any
Charged negative [D] D 3
Charged negative [E] E 4
Small Sm any
Small Sm 0-1
Small Sm 1-2
α-Helix propensity - high αH Hig
α-Helix propensity - low αH Min
α-Helix flexibility [G] G 0
α-Helix kink [P] P 2
Disulfide-forming (S-S) [C] C 2
Gap (no amino acid) -
RESIDUE Z-SCALES
Z1 (Lipophilicity)
Z2 (Steric properties)
Z3 (Electronic properties)
Z4 (PC1 several properties)
Z5 (PC2 several properties)
Residue number
Sequence-based ()
Structure-based (GPCRdb)
 
G.HN   G.hns1   G.S1   G.s1h1   G.H1   G.h1ha   H.HA   H.hahb   H.HB   H.hbhc   H.HC   H.hchd   H.HD   H.hdhe   H.HE   H.hehf   H.HF   G.hfs2   G.S2   G.s2s3   G.S3   G.s3h2   G.H2   G.h2s4   G.S4   G.s4h3   G.H3   G.h3s5   G.S5   G.s5hg   G.HG   G.hgh4   G.H4   G.h4s6   G.S6   G.s6h5   G.H5  
HN.01 HN.02 HN.03 HN.04 HN.05 HN.06 HN.07 HN.08 HN.09 HN.10 HN.11 HN.12 HN.13 HN.14 HN.15 HN.16 HN.17 HN.18 HN.19 HN.20 HN.21 HN.22 HN.23 HN.24 HN.25 HN.26 HN.27 HN.28 HN.29 HN.30 HN.31 HN.32 HN.33 HN.34 HN.35 HN.36 HN.37 HN.38 HN.39 HN.40 HN.41 HN.42 HN.43 HN.44 HN.45 HN.46 HN.47 HN.48 HN.49 HN.50 HN.51 HN.52 HN.53   hns1.01 hns1.02 hns1.03   S1.01 S1.02 S1.03 S1.04 S1.05 S1.06 S1.07   s1h1.01 s1h1.02 s1h1.03 s1h1.04 s1h1.05 s1h1.06   H1.01 H1.02 H1.03 H1.04 H1.05 H1.06 H1.07 H1.08 H1.09 H1.10 H1.11 H1.12   h1ha.01 h1ha.02 h1ha.03 h1ha.04 h1ha.05   HA.01 HA.02 HA.03 HA.04 HA.05 HA.06 HA.07 HA.08 HA.09 HA.10 HA.11 HA.12 HA.13 HA.14 HA.15 HA.16 HA.17 HA.18 HA.19 HA.20 HA.21 HA.22 HA.23 HA.24 HA.25 HA.26 HA.27 HA.28 HA.29   hahb.01 hahb.04 hahb.05 hahb.06 hahb.07 hahb.08 hahb.09   HB.01 HB.02 HB.03 HB.04 HB.05 HB.06 HB.07 HB.08 HB.09 HB.10 HB.11 HB.12 HB.13 HB.14   hbhc.01 hbhc.02 hbhc.03 hbhc.04 hbhc.05 hbhc.10 hbhc.11 hbhc.12 hbhc.13 hbhc.14 hbhc.15   HC.01 HC.02 HC.03 HC.04 HC.05 HC.06 HC.07 HC.08 HC.09 HC.10 HC.11 HC.12   hchd.01   HD.01 HD.02 HD.03 HD.04 HD.05 HD.06 HD.07 HD.08 HD.09 HD.10 HD.11 HD.12   hdhe.01 hdhe.02 hdhe.03 hdhe.04 hdhe.05   HE.01 HE.02 HE.03 HE.04 HE.05 HE.06 HE.07 HE.08 HE.09 HE.10 HE.11 HE.12 HE.13   hehf.01 hehf.02 hehf.03 hehf.04 hehf.05 hehf.06 hehf.07   HF.01 HF.02 HF.03 HF.04 HF.05 HF.06   hfs2.01 hfs2.02 hfs2.03 hfs2.04 hfs2.05 hfs2.06 hfs2.07   S2.01 S2.02 S2.03 S2.04 S2.05 S2.06 S2.07 S2.08   s2s3.01 s2s3.02   S3.01 S3.02 S3.03 S3.04 S3.05 S3.06 S3.07 S3.08   s3h2.01 s3h2.02 s3h2.03   H2.01 H2.02 H2.03 H2.04 H2.05 H2.06 H2.07 H2.08 H2.09 H2.10   h2s4.01 h2s4.02 h2s4.03 h2s4.04 h2s4.05   S4.01 S4.02 S4.03 S4.04 S4.05 S4.06 S4.07   s4h3.01 s4h3.02 s4h3.03 s4h3.04 s4h3.05 s4h3.06 s4h3.07 s4h3.08 s4h3.09 s4h3.10 s4h3.11 s4h3.12 s4h3.13 s4h3.14 s4h3.15   H3.01 H3.02 H3.03 H3.04 H3.05 H3.06 H3.07 H3.08 H3.09 H3.10 H3.11 H3.12 H3.13 H3.14 H3.15 H3.16 H3.17 H3.18   h3s5.01 h3s5.02 h3s5.03   S5.01 S5.02 S5.03 S5.04 S5.05 S5.06 S5.07   s5hg.01   HG.01 HG.02 HG.03 HG.04 HG.05 HG.06 HG.07 HG.08 HG.09 HG.12 HG.13 HG.14 HG.15 HG.16 HG.17   hgh4.01 hgh4.02 hgh4.03 hgh4.04 hgh4.05 hgh4.06 hgh4.07 hgh4.08   H4.01 H4.02 H4.03 H4.04 H4.05 H4.06 H4.07 H4.08 H4.09 H4.10 H4.11 H4.12 H4.13 H4.14 H4.15 H4.16 H4.17   h4s6.01 h4s6.08 h4s6.09 h4s6.10 h4s6.11 h4s6.12 h4s6.19 h4s6.20   S6.01 S6.02 S6.03 S6.04 S6.05   s6h5.01 s6h5.02 s6h5.03 s6h5.04 s6h5.05   H5.01 H5.02 H5.03 H5.04 H5.05 H5.06 H5.07 H5.08 H5.09 H5.10 H5.11 H5.12 H5.13 H5.14 H5.15 H5.16 H5.17 H5.18 H5.19 H5.20 H5.21 H5.22 H5.23 H5.24 H5.25 H5.26  
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HN.01 HN.02 HN.03 HN.04 HN.05 HN.06 HN.07 HN.08 HN.09 HN.10 HN.11 HN.12 HN.13 HN.14 HN.15 HN.16 HN.17 HN.18 HN.19 HN.20 HN.21 HN.22 HN.23 HN.24 HN.25 HN.26 HN.27 HN.28 HN.29 HN.30 HN.31 HN.32 HN.33 HN.34 HN.35 HN.36 HN.37 HN.38 HN.39 HN.40 HN.41 HN.42 HN.43 HN.44 HN.45 HN.46 HN.47 HN.48 HN.49 HN.50 HN.51 HN.52 HN.53   hns1.01 hns1.02 hns1.03   S1.01 S1.02 S1.03 S1.04 S1.05 S1.06 S1.07   s1h1.01 s1h1.02 s1h1.03 s1h1.04 s1h1.05 s1h1.06   H1.01 H1.02 H1.03 H1.04 H1.05 H1.06 H1.07 H1.08 H1.09 H1.10 H1.11 H1.12   h1ha.01 h1ha.02 h1ha.03 h1ha.04 h1ha.05   HA.01 HA.02 HA.03 HA.04 HA.05 HA.06 HA.07 HA.08 HA.09 HA.10 HA.11 HA.12 HA.13 HA.14 HA.15 HA.16 HA.17 HA.18 HA.19 HA.20 HA.21 HA.22 HA.23 HA.24 HA.25 HA.26 HA.27 HA.28 HA.29   hahb.01 hahb.04 hahb.05 hahb.06 hahb.07 hahb.08 hahb.09   HB.01 HB.02 HB.03 HB.04 HB.05 HB.06 HB.07 HB.08 HB.09 HB.10 HB.11 HB.12 HB.13 HB.14   hbhc.01 hbhc.02 hbhc.03 hbhc.04 hbhc.05 hbhc.10 hbhc.11 hbhc.12 hbhc.13 hbhc.14 hbhc.15   HC.01 HC.02 HC.03 HC.04 HC.05 HC.06 HC.07 HC.08 HC.09 HC.10 HC.11 HC.12   hchd.01   HD.01 HD.02 HD.03 HD.04 HD.05 HD.06 HD.07 HD.08 HD.09 HD.10 HD.11 HD.12   hdhe.01 hdhe.02 hdhe.03 hdhe.04 hdhe.05   HE.01 HE.02 HE.03 HE.04 HE.05 HE.06 HE.07 HE.08 HE.09 HE.10 HE.11 HE.12 HE.13   hehf.01 hehf.02 hehf.03 hehf.04 hehf.05 hehf.06 hehf.07   HF.01 HF.02 HF.03 HF.04 HF.05 HF.06   hfs2.01 hfs2.02 hfs2.03 hfs2.04 hfs2.05 hfs2.06 hfs2.07   S2.01 S2.02 S2.03 S2.04 S2.05 S2.06 S2.07 S2.08   s2s3.01 s2s3.02   S3.01 S3.02 S3.03 S3.04 S3.05 S3.06 S3.07 S3.08   s3h2.01 s3h2.02 s3h2.03   H2.01 H2.02 H2.03 H2.04 H2.05 H2.06 H2.07 H2.08 H2.09 H2.10   h2s4.01 h2s4.02 h2s4.03 h2s4.04 h2s4.05   S4.01 S4.02 S4.03 S4.04 S4.05 S4.06 S4.07   s4h3.01 s4h3.02 s4h3.03 s4h3.04 s4h3.05 s4h3.06 s4h3.07 s4h3.08 s4h3.09 s4h3.10 s4h3.11 s4h3.12 s4h3.13 s4h3.14 s4h3.15   H3.01 H3.02 H3.03 H3.04 H3.05 H3.06 H3.07 H3.08 H3.09 H3.10 H3.11 H3.12 H3.13 H3.14 H3.15 H3.16 H3.17 H3.18   h3s5.01 h3s5.02 h3s5.03   S5.01 S5.02 S5.03 S5.04 S5.05 S5.06 S5.07   s5hg.01   HG.01 HG.02 HG.03 HG.04 HG.05 HG.06 HG.07 HG.08 HG.09 HG.12 HG.13 HG.14 HG.15 HG.16 HG.17   hgh4.01 hgh4.02 hgh4.03 hgh4.04 hgh4.05 hgh4.06 hgh4.07 hgh4.08   H4.01 H4.02 H4.03 H4.04 H4.05 H4.06 H4.07 H4.08 H4.09 H4.10 H4.11 H4.12 H4.13 H4.14 H4.15 H4.16 H4.17   h4s6.01 h4s6.08 h4s6.09 h4s6.10 h4s6.11 h4s6.12 h4s6.19 h4s6.20   S6.01 S6.02 S6.03 S6.04 S6.05   s6h5.01 s6h5.02 s6h5.03 s6h5.04 s6h5.05   H5.01 H5.02 H5.03 H5.04 H5.05 H5.06 H5.07 H5.08 H5.09 H5.10 H5.11 H5.12 H5.13 H5.14 H5.15 H5.16 H5.17 H5.18 H5.19 H5.20 H5.21 H5.22 H5.23 H5.24 H5.25 H5.26  
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-2.9
2.4
1.8
-2.6
-2.6
3.5
0.8
-4.3
2.4
3.5
0.8
-4.3
-4.3
-1.7
0.2
3.1
0.5
2.3
2.1
0.7
2.9
3.1
3.3
3.4
0.1
2.1
2.2
1.6
0.5
3.5
4.0
0.5
3.1
3.5
3.1
0.2
3.5
3.5
3.5
2.4
3.5
3.9
-3.9
4.0
0.2
-4.3
-4.3
0.2
3.5
3.1
3.5
3.5
0.2
 
-2.6
3.5
3.5
 
-4.3
-2.6
2.3
-3.9
-4.3
-4.3
-4.3
 
2.1
0.2
2.1
3.1
2.4
2.1
 
2.3
2.4
0.8
-4.2
-4.3
2.3
1.8
-2.9
3.5
-3.9
-3.9
2.5
 
2.1
3.5
3.1
-4.2
4.0
 
1.8
2.3
0.2
-4.3
-4.3
3.1
-4.2
3.5
4.0
0.8
-3.9
-4.2
3.5
3.1
-3.7
-3.9
2.3
2.0
2.4
3.5
-2.6
-4.3
-2.6
4.0
0.2
3.5
4.0
2.3
-4.3
 
2.0
-3.9
-1.7
-4.4
1.8
-1.5
2.4
 
3.1
3.0
3.1
2.3
2.5
2.0
-2.9
-4.2
-4.3
-3.0
0.4
-4.2
3.1
3.0
 
2.4
0.2
2.0
-4.1
-1.7
-2.7
3.2
-1.7
0.2
0.8
-4.2
 
1.8
-4.3
-2.5
-2.6
-1.7
0.2
-4.3
2.4
0.2
-4.3
-4.4
3.4
 
4.0
 
2.4
2.0
-3.9
3.4
3.1
0.2
-4.1
2.4
3.5
3.5
2.4
3.1
 
-4.1
1.8
-4.3
2.0
3.1
 
2.4
-2.6
2.3
-2.5
-4.2
-4.3
4.0
3.0
-4.3
4.0
3.5
-3.9
2.0
 
1.8
-4.3
3.0
-2.5
-4.2
-1.7
2.4
 
2.3
1.8
4.0
-3.9
-4.3
-4.3
 
0.2
3.5
2.3
0.2
0.8
2.3
2.0
 
-3.9
-2.4
3.1
2.5
4.0
-4.2
-2.7
-3.9
 
2.3
2.3
 
-3.9
-1.7
-4.2
2.3
-2.9
-2.6
4.0
-2.6
 
2.0
2.0
1.8
 
3.5
2.4
1.8
3.5
1.8
2.3
-4.4
-4.2
1.8
0.8
 
-4.2
4.0
2.0
-3.9
0.8
 
2.4
-3.9
-4.3
-4.2
-2.9
-2.6
2.4
 
2.4
2.4
3.1
-2.6
4.0
1.8
-2.6
-4.3
-2.9
3.1
4.0
3.5
3.5
0.8
3.0
 
3.5
-4.3
-2.7
3.1
2.4
-2.9
3.0
-3.9
-4.2
3.1
0.8
-3.9
-2.6
3.0
3.0
2.3
-4.3
-4.2
 
-4.1
3.0
-2.6
 
2.4
-3.9
-3.9
-4.3
-4.2
-4.3
3.0
 
2.3
 
-2.5
4.0
-4.3
-4.3
-2.6
3.1
2.3
-2.6
2.3
0.9
-2.6
2.4
-3.9
2.3
2.3
 
2.5
-4.2
-1.0
4.0
-4.2
2.8
2.0
4.0
 
-1.7
2.5
3.5
-4.3
3.1
4.0
-2.6
1.8
3.4
-2.7
-4.3
-2.6
1.8
0.9
-4.2
4.0
3.5
 
2.3
3.5
3.5
3.0
3.5
2.4
2.3
-1.7
 
-4.3
-4.2
2.5
2.5
-4.2
 
0.8
0.8
0.2
-3.9
4.0
 
0.8
3.1
3.0
-3.4
3.5
-4.2
-2.6
-4.2
2.5
0.2
-2.6
2.3
4.0
0.8
-3.9
-4.3
1.8
3.1
3.0
-4.3
2.3
4.0
-3.9
-2.9
-4.3
1.8
 
-0.2
-1.1
-3.9
-2.6
-2.6
2.5
-2.2
-1.3
-1.1
2.5
-1.7
-1.3
-1.3
0.3
-2.3
0.3
-2.2
-2.9
-4.1
-1.7
2.3
0.4
2.3
2.1
-2.5
-4.1
-2.8
-3.7
-2.2
2.5
0.9
-2.2
0.3
2.5
0.3
-2.3
2.5
2.5
2.5
-1.1
2.5
0.9
-1.7
0.9
-2.3
-1.3
-1.3
-2.3
2.5
0.3
2.5
2.5
-2.3
 
-2.6
2.5
2.5
 
-1.3
-2.6
0.9
-1.7
-1.3
-1.3
-1.3
 
-4.1
-2.3
-4.1
0.3
-1.1
-4.1
 
0.9
-1.1
-2.2
1.9
-1.3
0.9
0.5
-0.2
2.5
-1.7
-1.7
1.9
 
-4.1
2.5
0.3
1.9
0.9
 
0.5
0.9
-2.3
-1.3
-1.3
0.3
1.9
2.5
0.9
-2.2
-1.7
1.9
0.8
1.6
-1.6
-1.1
0.8
-4.1
-1.1
2.4
-2.6
-1.3
-2.6
0.9
-2.3
2.5
0.9
0.9
-1.3
 
-4.1
-1.7
0.3
3.9
0.5
2.3
-1.1
 
0.3
1.6
0.3
0.9
2.0
-4.1
-0.2
1.9
-1.3
-0.3
-2.3
1.9
0.3
1.6
 
1.0
-2.3
-4.1
-1.2
0.3
-2.6
0.3
0.3
-2.3
-2.2
1.9
 
0.5
-1.3
2.4
-2.6
0.3
-2.3
-1.3
-1.2
-2.3
-1.3
3.9
2.1
 
0.9
 
-1.1
-4.1
-1.7
2.3
0.3
-2.3
2.0
-1.1
2.5
2.5
-1.1
0.3
 
2.0
0.5
-1.3
-4.1
0.3
 
-1.1
-2.6
0.9
2.4
1.9
-1.3
0.9
1.6
-1.3
0.9
2.5
-1.7
-4.1
 
0.5
-1.3
1.6
2.4
1.8
0.3
-1.1
 
0.9
0.5
0.9
-1.7
-1.3
-1.3
 
-2.3
2.5
0.9
-2.3
-2.2
0.9
-4.1
 
-1.7
-2.6
0.3
2.0
0.9
1.9
-2.5
-1.7
 
0.9
0.9
 
-1.7
0.3
1.9
0.9
-0.2
-2.6
0.9
-2.6
 
-4.1
-4.1
0.5
 
2.5
-1.1
0.5
2.5
0.5
0.9
3.9
1.9
0.5
-1.7
 
1.9
0.9
-4.1
-1.7
-2.2
 
-1.1
-1.7
-1.3
1.9
-0.2
-2.6
-1.1
 
-1.1
-1.1
0.3
2.4
0.9
0.5
-2.6
-1.3
-0.2
0.3
0.9
2.5
2.5
-2.2
1.6
 
2.5
-1.3
-2.6
0.3
-1.1
-0.2
1.6
-1.7
1.9
0.3
-2.2
-1.7
-2.6
1.6
1.6
0.9
-1.3
1.9
 
1.5
1.6
-2.6
 
-1.1
-1.7
-1.7
-1.3
1.9
-1.3
1.6
 
0.9
 
-0.4
0.9
-1.3
-1.3
-2.6
0.3
0.9
-2.6
0.9
-2.1
-2.6
-1.1
-1.7
1.0
0.9
 
2.0
1.9
0.1
0.9
1.9
1.6
-4.1
0.9
 
0.3
2.0
2.5
-1.3
0.3
0.9
-2.6
0.5
2.3
2.4
-1.3
-2.6
0.5
-1.8
1.9
0.9
2.5
 
0.9
2.5
2.5
1.6
2.5
-1.2
0.9
0.3
 
-1.3
1.9
2.0
2.0
1.9
 
-2.2
-2.2
-2.3
-1.7
0.9
 
-2.2
0.3
1.6
-2.1
2.5
1.9
-2.6
1.9
2.0
-2.3
-2.6
0.9
0.9
-2.2
-1.7
-1.3
0.5
0.3
1.6
-1.3
0.9
0.9
-1.7
-0.2
-1.3
0.5
 
0.5
1.2
0.4
-1.5
-1.5
-3.5
-1.1
-1.5
1.2
-3.5
3.8
-1.5
-1.5
1.8
0.6
-0.1
0.7
-0.0
0.4
0.1
-2.9
0.0
-3.3
-3.0
0.3
0.4
0.7
0.4
0.7
-3.5
1.9
0.7
-0.1
-3.5
-0.1
0.6
-3.5
-3.5
-3.5
1.2
-3.5
1.7
-1.7
1.9
0.6
-1.5
-1.5
0.6
-3.5
-0.1
-3.5
-3.5
0.6
 
-1.5
-3.5
-3.5
 
-1.5
-1.5
-2.5
-1.7
-1.5
-1.5
-1.5
 
0.4
0.6
0.4
-0.1
1.2
0.4
 
-2.5
1.2
-1.1
1.1
-1.5
-2.5
-1.4
0.5
-3.5
-1.7
-1.7
0.3
 
0.4
-3.5
-0.1
1.1
1.9
 
-1.4
-2.5
0.6
-1.5
-1.5
-0.1
1.1
-3.5
1.9
-1.1
-1.7
1.1
1.7
1.1
-1.6
-1.2
-2.2
0.4
1.1
-3.4
-1.5
-1.5
-1.5
1.9
0.6
-3.5
1.9
-2.5
-1.5
 
0.4
-1.7
1.8
0.6
-1.4
0.4
1.1
 
-0.1
1.0
-0.1
-2.5
0.3
0.4
0.5
1.1
-1.5
0.3
0.6
1.1
-0.1
1.0
 
-2.5
0.6
0.4
-1.3
1.8
-1.5
-0.0
1.8
0.6
-1.1
1.1
 
-1.4
-1.5
0.4
-1.5
1.8
0.6
-1.5
1.1
0.6
-1.5
0.6
-3.2
 
1.9
 
1.1
0.4
-1.7
-3.4
-0.1
0.6
1.0
1.1
-3.5
-3.5
1.1
-0.1
 
1.0
-1.4
-1.5
0.4
-0.1
 
1.1
-1.5
-2.5
0.4
1.1
-1.5
1.9
1.0
-1.5
1.9
-3.5
-1.7
0.4
 
-1.4
-1.5
1.0
0.4
0.9
1.8
1.1
 
-2.5
-1.4
1.9
-1.7
-1.5
-1.5
 
0.6
-3.5
-2.5
0.6
-1.1
-2.5
0.4
 
-1.7
-1.4
-0.1
0.3
1.9
1.1
-1.6
-1.7
 
-2.5
-2.5
 
-1.7
1.8
1.1
-2.5
0.5
-1.5
1.9
-1.5
 
0.4
0.4
-1.4
 
-3.5
1.1
-1.4
-3.5
-1.4
-2.5
0.6
1.1
-1.4
3.8
 
1.1
1.9
0.4
-1.7
-1.1
 
1.1
-1.7
-1.5
1.1
0.5
-1.5
1.1
 
1.1
1.1
-0.1
0.5
1.9
-1.4
-1.5
-1.5
0.5
-0.1
1.9
-3.5
-3.3
-1.1
1.0
 
-3.5
-1.5
-1.5
-0.1
1.1
0.5
1.0
-1.7
1.1
-0.1
-1.1
-1.7
-1.5
1.0
1.0
-2.5
-1.5
1.1
 
0.8
1.0
-1.5
 
1.1
-1.7
-1.7
-1.5
1.1
-1.5
1.0
 
-2.5
 
0.3
1.9
-1.5
-1.5
-1.5
-0.1
-2.5
-1.5
-2.5
-0.9
-1.5
1.1
-1.7
-2.5
-2.5
 
0.3
1.1
1.7
1.9
1.1
-2.9
0.4
1.9
 
1.8
0.3
-3.5
-1.5
-0.1
1.9
-1.5
-1.4
-3.1
0.5
-1.5
-1.5
-1.4
3.6
1.1
1.9
-3.5
 
-2.5
-3.5
-3.5
1.0
-3.5
1.1
-2.5
1.8
 
-1.5
1.1
0.3
0.3
1.1
 
-1.1
-1.1
0.6
-1.7
1.9
 
-1.1
-0.1
1.0
-1.6
-3.5
1.1
-1.5
1.1
0.3
0.6
-1.5
-2.5
1.9
-1.1
-1.7
-1.5
-1.4
-0.1
1.0
-1.5
-2.5
1.9
-1.7
0.5
-1.5
-1.4
 
1.9
-1.4
-0.7
-0.9
-0.9
2.0
-1.5
-0.7
-1.4
2.0
0.2
-0.7
-0.7
0.7
-0.1
-3.0
-0.3
-0.5
-0.8
0.1
1.8
-2.8
1.6
1.6
-0.3
-0.8
-1.1
-0.7
-0.3
2.0
-2.5
-0.3
-3.0
2.0
-3.0
-0.1
2.0
2.0
2.0
-1.4
2.0
-2.5
-0.8
-2.5
-0.1
-0.7
-0.7
-0.1
2.0
-3.0
2.0
2.0
-0.1
 
-0.9
2.0
2.0
 
-0.7
-0.9
1.5
-0.8
-0.7
-0.7
-0.7
 
-0.8
-0.1
-0.8
-3.0
-1.4
-0.8
 
1.5
-1.4
-1.5
0.5
-0.7
1.5
-1.3
1.9
2.0
-0.8
-0.8
3.9
 
-0.8
2.0
-3.0
0.5
-2.5
 
-1.3
1.5
-0.1
-0.7
-0.7
-3.0
0.5
2.0
-2.5
-1.5
-0.8
0.5
-2.2
-1.2
-0.8
-0.7
0.9
-0.8
-1.4
2.0
-0.9
-0.7
-0.9
-2.5
-0.1
2.0
-2.5
1.5
-0.7
 
-0.8
-0.8
0.7
3.4
-1.3
0.9
-1.4
 
-3.0
-1.1
-3.0
1.5
3.9
-0.8
1.9
0.5
-0.7
1.7
-0.2
0.5
-3.0
-1.1
 
1.5
-0.1
-0.8
-0.4
0.7
-0.8
-3.0
0.7
-0.1
-1.5
0.5
 
-1.3
-0.7
0.0
-0.9
0.7
-0.1
-0.7
-1.4
-0.1
-0.7
3.4
1.8
 
-2.5
 
-1.4
-0.8
-0.8
1.9
-3.0
-0.1
0.5
-1.4
2.0
2.0
-1.4
-3.0
 
0.5
-1.3
-0.7
-0.8
-3.0
 
-1.4
-0.9
1.5
0.0
0.5
-0.7
-2.5
-1.1
-0.7
-2.5
2.0
-0.8
-0.8
 
-1.3
-0.7
-1.1
0.0
0.5
0.7
-1.4
 
1.5
-1.3
-2.5
-0.8
-0.7
-0.7
 
-0.1
2.0
1.5
-0.1
-1.5
1.5
-0.8
 
-0.8
-0.8
-3.0
3.9
-2.5
0.5
-0.8
-0.8
 
1.5
1.5
 
-0.8
0.7
0.5
1.5
1.9
-0.9
-2.5
-0.9
 
-0.8
-0.8
-1.3
 
2.0
-1.4
-1.3
2.0
-1.3
1.5
3.4
0.5
-1.3
0.2
 
0.5
-2.5
-0.8
-0.8
-1.5
 
-1.4
-0.8
-0.7
0.5
1.9
-0.9
-1.4
 
-1.4
-1.4
-3.0
0.1
-2.5
-1.3
-0.9
-0.7
1.9
-3.0
-2.5
2.0
2.1
-1.5
-1.1
 
2.0
-0.7
-0.8
-3.0
-1.4
1.9
-1.1
-0.8
0.5
-3.0
-1.5
-0.8
-0.9
-1.1
-1.1
1.5
-0.7
0.5
 
0.4
-1.1
-0.9
 
-1.4
-0.8
-0.8
-0.7
0.5
-0.7
-1.1
 
1.5
 
1.6
-2.5
-0.7
-0.7
-0.9
-3.0
1.5
-0.9
1.5
-1.5
-0.9
-1.4
-0.8
1.4
1.5
 
3.9
0.5
0.4
-2.5
0.5
1.6
-0.8
-2.5
 
0.7
3.9
2.0
-0.7
-3.0
-2.5
-0.9
-1.3
1.9
0.1
-0.7
-0.9
-1.3
0.1
0.5
-2.5
2.0
 
1.5
2.0
2.0
-1.1
2.0
-1.4
1.5
0.7
 
-0.7
0.5
3.9
3.9
0.5
 
-1.5
-1.5
-0.1
-0.8
-2.5
 
-1.5
-3.0
-1.1
-0.8
2.0
0.5
-0.9
0.5
3.9
-0.1
-0.9
1.5
-2.5
-1.5
-0.8
-0.7
-1.3
-3.0
-1.1
-0.7
1.5
-2.5
-0.8
1.9
-0.7
-1.3
 
-1.0
0.7
-0.2
-0.0
-0.0
-0.2
-0.4
0.8
0.7
-0.2
-2.7
0.8
0.8
2.0
1.3
-0.3
1.2
-0.2
-0.4
1.1
0.1
-0.0
-0.1
-0.1
1.0
-0.4
0.1
-0.0
1.2
-0.2
0.8
1.2
-0.3
-0.2
-0.3
1.3
-0.2
-0.2
-0.2
0.7
-0.2
0.7
0.3
0.8
1.3
0.8
0.8
1.3
-0.2
-0.3
-0.2
-0.2
1.3
 
-0.0
-0.2
-0.2
 
0.8
-0.0
0.3
0.3
0.8
0.8
0.8
 
-0.4
1.3
-0.4
-0.3
0.7
-0.4
 
0.3
0.7
-0.4
-0.6
0.8
0.3
0.7
-1.0
-0.2
0.3
0.3
0.1
 
-0.4
-0.2
-0.3
-0.6
0.8
 
0.7
0.3
1.3
0.8
0.8
-0.3
-0.6
-0.2
0.8
-0.4
0.3
-0.6
0.6
1.6
0.1
0.7
0.3
-0.4
0.7
-0.1
-0.0
0.8
-0.0
0.8
1.3
-0.2
0.8
0.3
0.8
 
-0.4
0.3
2.0
-1.6
0.7
-1.1
0.7
 
-0.3
1.6
-0.3
0.3
0.1
-0.4
-1.0
-0.6
0.8
-0.8
1.3
-0.6
-0.3
1.6
 
0.3
1.3
-0.4
0.6
2.0
0.0
-0.2
2.0
1.3
-0.4
-0.6
 
0.7
0.8
-1.5
-0.0
2.0
1.3
0.8
0.6
1.3
0.8
-1.6
-0.2
 
0.8
 
0.7
-0.4
0.3
-0.1
-0.3
1.3
-0.7
0.7
-0.2
-0.2
0.7
-0.3
 
-0.7
0.7
0.8
-0.4
-0.3
 
0.7
-0.0
0.3
-1.5
-0.6
0.8
0.8
1.6
0.8
0.8
-0.2
0.3
-0.4
 
0.7
0.8
1.6
-1.5
-0.5
2.0
0.7
 
0.3
0.7
0.8
0.3
0.8
0.8
 
1.3
-0.2
0.3
1.3
-0.4
0.3
-0.4
 
0.3
0.0
-0.3
0.1
0.8
-0.6
0.0
0.3
 
0.3
0.3
 
0.3
2.0
-0.6
0.3
-1.0
-0.0
0.8
-0.0
 
-0.4
-0.4
0.7
 
-0.2
0.7
0.7
-0.2
0.7
0.3
-1.6
-0.6
0.7
-2.7
 
-0.6
0.8
-0.4
0.3
-0.4
 
0.7
0.3
0.8
-0.6
-1.0
-0.0
0.7
 
0.7
0.7
-0.3
-1.4
0.8
0.7
-0.0
0.8
-1.0
-0.3
0.8
-0.2
-0.2
-0.4
1.6
 
-0.2
0.8
0.0
-0.3
0.7
-1.0
1.6
0.3
-0.6
-0.3
-0.4
0.3
-0.0
1.6
1.6
0.3
0.8
-0.6
 
-0.5
1.6
-0.0
 
0.7
0.3
0.3
0.8
-0.6
0.8
1.6
 
0.3
 
-0.9
0.8
0.8
0.8
-0.0
-0.3
0.3
-0.0
0.3
-0.3
-0.0
0.7
0.3
0.3
0.3
 
0.1
-0.6
1.8
0.8
-0.6
0.1
-0.4
0.8
 
2.0
0.1
-0.2
0.8
-0.3
0.8
-0.0
0.7
-0.3
-1.4
0.8
-0.0
0.7
-2.5
-0.6
0.8
-0.2
 
0.3
-0.2
-0.2
1.6
-0.2
0.6
0.3
2.0
 
0.8
-0.6
0.1
0.1
-0.6
 
-0.4
-0.4
1.3
0.3
0.8
 
-0.4
-0.3
1.6
0.2
-0.2
-0.6
-0.0
-0.6
0.1
1.3
-0.0
0.3
0.8
-0.4
0.3
0.8
0.7
-0.3
1.6
0.8
0.3
0.8
0.3
-1.0
0.8
0.7
 
HN.01 HN.02 HN.03 HN.04 HN.05 HN.06 HN.07 HN.08 HN.09 HN.10 HN.11 HN.12 HN.13 HN.14 HN.15 HN.16 HN.17 HN.18 HN.19 HN.20 HN.21 HN.22 HN.23 HN.24 HN.25 HN.26 HN.27 HN.28 HN.29 HN.30 HN.31 HN.32 HN.33 HN.34 HN.35 HN.36 HN.37 HN.38 HN.39 HN.40 HN.41 HN.42 HN.43 HN.44 HN.45 HN.46 HN.47 HN.48 HN.49 HN.50 HN.51 HN.52 HN.53   hns1.01 hns1.02 hns1.03   S1.01 S1.02 S1.03 S1.04 S1.05 S1.06 S1.07   s1h1.01 s1h1.02 s1h1.03 s1h1.04 s1h1.05 s1h1.06   H1.01 H1.02 H1.03 H1.04 H1.05 H1.06 H1.07 H1.08 H1.09 H1.10 H1.11 H1.12   h1ha.01 h1ha.02 h1ha.03 h1ha.04 h1ha.05   HA.01 HA.02 HA.03 HA.04 HA.05 HA.06 HA.07 HA.08 HA.09 HA.10 HA.11 HA.12 HA.13 HA.14 HA.15 HA.16 HA.17 HA.18 HA.19 HA.20 HA.21 HA.22 HA.23 HA.24 HA.25 HA.26 HA.27 HA.28 HA.29   hahb.01 hahb.04 hahb.05 hahb.06 hahb.07 hahb.08 hahb.09   HB.01 HB.02 HB.03 HB.04 HB.05 HB.06 HB.07 HB.08 HB.09 HB.10 HB.11 HB.12 HB.13 HB.14   hbhc.01 hbhc.02 hbhc.03 hbhc.04 hbhc.05 hbhc.10 hbhc.11 hbhc.12 hbhc.13 hbhc.14 hbhc.15   HC.01 HC.02 HC.03 HC.04 HC.05 HC.06 HC.07 HC.08 HC.09 HC.10 HC.11 HC.12   hchd.01   HD.01 HD.02 HD.03 HD.04 HD.05 HD.06 HD.07 HD.08 HD.09 HD.10 HD.11 HD.12   hdhe.01 hdhe.02 hdhe.03 hdhe.04 hdhe.05   HE.01 HE.02 HE.03 HE.04 HE.05 HE.06 HE.07 HE.08 HE.09 HE.10 HE.11 HE.12 HE.13   hehf.01 hehf.02 hehf.03 hehf.04 hehf.05 hehf.06 hehf.07   HF.01 HF.02 HF.03 HF.04 HF.05 HF.06   hfs2.01 hfs2.02 hfs2.03 hfs2.04 hfs2.05 hfs2.06 hfs2.07   S2.01 S2.02 S2.03 S2.04 S2.05 S2.06 S2.07 S2.08   s2s3.01 s2s3.02   S3.01 S3.02 S3.03 S3.04 S3.05 S3.06 S3.07 S3.08   s3h2.01 s3h2.02 s3h2.03   H2.01 H2.02 H2.03 H2.04 H2.05 H2.06 H2.07 H2.08 H2.09 H2.10   h2s4.01 h2s4.02 h2s4.03 h2s4.04 h2s4.05   S4.01 S4.02 S4.03 S4.04 S4.05 S4.06 S4.07   s4h3.01 s4h3.02 s4h3.03 s4h3.04 s4h3.05 s4h3.06 s4h3.07 s4h3.08 s4h3.09 s4h3.10 s4h3.11 s4h3.12 s4h3.13 s4h3.14 s4h3.15   H3.01 H3.02 H3.03 H3.04 H3.05 H3.06 H3.07 H3.08 H3.09 H3.10 H3.11 H3.12 H3.13 H3.14 H3.15 H3.16 H3.17 H3.18   h3s5.01 h3s5.02 h3s5.03   S5.01 S5.02 S5.03 S5.04 S5.05 S5.06 S5.07   s5hg.01   HG.01 HG.02 HG.03 HG.04 HG.05 HG.06 HG.07 HG.08 HG.09 HG.12 HG.13 HG.14 HG.15 HG.16 HG.17   hgh4.01 hgh4.02 hgh4.03 hgh4.04 hgh4.05 hgh4.06 hgh4.07 hgh4.08   H4.01 H4.02 H4.03 H4.04 H4.05 H4.06 H4.07 H4.08 H4.09 H4.10 H4.11 H4.12 H4.13 H4.14 H4.15 H4.16 H4.17   h4s6.01 h4s6.08 h4s6.09 h4s6.10 h4s6.11 h4s6.12 h4s6.19 h4s6.20   S6.01 S6.02 S6.03 S6.04 S6.05   s6h5.01 s6h5.02 s6h5.03 s6h5.04 s6h5.05   H5.01 H5.02 H5.03 H5.04 H5.05 H5.06 H5.07 H5.08 H5.09 H5.10 H5.11 H5.12 H5.13 H5.14 H5.15 H5.16 H5.17 H5.18 H5.19 H5.20 H5.21 H5.22 H5.23 H5.24 H5.25 H5.26