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INFORMATION
Documentation
Tutorial
General introduction
Tutorial
Workshop materials
Workshop manual (PDF)
Workshop manual (Word)
Workshop videos
FOR DEVELOPERS
Linking to GPCRdb
Web services
GPCRdb
Citing GPCRdb
Receptor page
Data Mapper
SEQUENCES
Sequence alignments
Generic residue number tables
Genetic variants
Variation coverage
Receptor variants
Estimated economic burden
Isoforms
SEQUENCE ANALYSIS
Receptor similarity
BLAST (GPCRdb alignment)
BLAST (non-GPCRdb query)
Phylogenetic trees
Similarity matrix (all-to-all)
Site search (by seq. motif)
STRUCTURES
Structure coverage
Structures
Structure models (receptor)
Structure models (ligand complexes)
Structure model validation
STRUCTURE ANALYSIS
Structure comparison tool
Structure similarity trees
Structure superposition
Generic residue numbering (PDB)
Structure similarity search
STRUCTURE CONSTRUCTS
Construct/Experiment design
Construct alignments
Construct design tool
Experiment browser
Truncation/Fusion analysis
Truncation sites
Fusion sites
Loop deletions
Mutation analysis
Stabilising mutations
StabMutAnalyser
Mutation substitution matrix
DETERMINANTS & MUTATIONS
Sequence signature tool
State stabilizing mutation design
Drugs
&
ligands
LIGANDS & BIOACTIVITIES
Ligand coverage
Ligands (ChEMBL, GtP, Ki db)
Ligands (by receptor query)
Ligands (by ligand query)
PHYSIOLOGICAL LIGANDS
Physiological ligands (GtP)
DRUGS & AGENTS IN TRIAL
Drug & Agents in trial
Agents/drugs by phase I-IV
Agent/drug page
Targets
Targets by phase I-IV
The drugged GPCRome
Target page
Target selection tool
Indications
Indication page
LIGAND SITES
GPCR-ligand interactions
Site search
Site search (by seq. motif)
Site search (by ligand complex)
LIGAND SITE MUTATIONS
Mutation coverage
Mutations
Mutation design tool
By receptor name
By PDB id
Mutation data submission
GproteinDb
Citing GproteinDb
G protein page
COUPLINGS
Couplings
Datasets
Biosensors
COUPLING ANALYSIS
Coupling selectivity (tree)
Coupling selectivity (Venn)
SEQUENCES
Sequence alignments
Generic residue number tables
STRUCTURES
Structure coverage
Structures
Structure models
STRUCTURE ANALYSIS
Interface interactions & profiling
Structure superposition
DETERMINANTS & MUTATIONS
Coupling determinant mutation design
Interface mutations & chimeras
ArrestinDb
Citing ArrestinDb
Arrestin page
COUPLINGS
Couplings
COUPLING ANALYSIS
Coupling selectivity (tree)
Coupling selectivity (Venn)
SEQUENCES
Sequence alignments
Generic residue number tables
STRUCTURES
Structure coverage
Structures
STRUCTURE ANALYSIS
Interface interactions (single structure)
DETERMINANTS & MUTATIONS
Interface mutations
Biased Signaling Atlas
Citing Biased Signaling Atlas
GUIDELINES
Community guidelines paper
Reference ligand selection
Template to calculate ligand bias factors
BIASED LIGANDS (for transducer family)
Biased ligand coverage
Biased ligands
Ligand bias rank orders
Ligand pathway profiles (Δlog(Emax/EC50))
Ligand pathway profiles (Δlog(Tau/KA))
BIASED LIGANDS (for transducer subtype)
Biased ligand coverage
Biased ligands
Ligand bias rank orders
Ligand pathway profiles (Δlog(Emax/EC50))
Ligand pathway profiles (Δlog(Tau/KA))
PATHWAY-PREFERRING LIGANDS (for transducer family)
Pathway-preferring ligand coverage
Pathway-preferring ligands (pathway ∆Log/(Emax/EC50)
Ligand pathway preference rank orders (Δlog(Emax/EC50))
Ligand pathway profiles (Log(Emax/EC50))
Pathways
Pathway effects
DATA DEPOSITION
Data submission
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Data annotation
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Structures
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Conformational clusters (tree of structures)
Tree as PDF Figure
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Tree in Newick format
Raw distance matrix in CSV
Structural analysis
(1 or 2 sets)
Tree type
Circular dendrogram
Horizontal dendrogram
Receptor names
IUPHAR
IUPHAR (PDB)
IUPHAR [inner] (PDB) [outer]
UniProt
UniProt (PDB)
UniProt [inner] (PDB) [outer]
PDB
Outer markers
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Activation state
Receptor activation state
Degree active (%)
TM6 opening (%)
Ligand function
Classification
GPCR class
Ligand type
Receptor family
G protein Coupling
All G proteins
Primary G proteins
Secondary G proteins
Structure
Structure determination method
Complexed effector protein
Inner markers
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Activation state
Receptor activation state
Ligand function
Classification
GPCR class
Ligand type
Receptor family
G protein Coupling
All G proteins
Primary G proteins
Secondary G proteins
Structure
Structure determination method
Complexed effector protein
Structure set 1
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