A literature-annotated dataset of bioactivities, primarily potency and E_max values, for physiological peptide hormones and their analogs. Each bioactivity was annotated from literature into a standardized spreadsheet.

Contents

• Class A (6,626 rows): neurokinin, vasopressin, orexin-A, substance P, MSH, GnRH, OT, ACTH, angiotensin II, Ccl1-28, Cx3Cl1, Cxcl1-17 and Xcl1.
• Class B1 (3,012 rows): α/β-CGRP, adrenomedullin (ADM), amylin, calcitonin (CT), gastric inhibitory peptide (GIP), GNRH, glucagon, PACAP, PTH, PTHRP, secretin, TIP39, urocortin-1 and VIP.

Use it to

• See which analogs have already been tested, and which have not.
• Analyze structure-activity relationships across published studies.