Number of structures, including multiple of same receptor (complex)
Class (Family) |
A (Rhodopsin) | B1 (Secretin) | B2 (Adhesion) | C (Glutamate) |
D1 (Ste2-like fungal pheromone) |
F (Frizzled) | T2 (Taste 2) | Total |
Receptors | 904 | 125 | 31 | 74 | 1 | 22 | 3 | 1160 |
Receptor - ligand complexes | 896 | 124 | 29 | 73 | 1 | 20 | 3 | 1146 |
Receptor - G protein complexes | 433 | 103 | 31 | 7 | 1 | 6 | 3 | 584 |
Active-state receptors* | 520 | 108 | 31 | 23 | 1 | 7 | 3 | 693 |
Number of unique receptor complexes
Class (Family) |
A (Rhodopsin) | B1 (Secretin) | B2 (Adhesion) | C (Glutamate) |
D1 (Ste2-like fungal pheromone) |
F (Frizzled) | T2 (Taste 2) | Total |
Receptors** | 147 | 15 | 9 | 10 | 1 | 4 | 1 | 187 |
Receptor - ligand complexes | 602 | 80 | 13 | 47 | 1 | 14 | 2 | 759 |
Receptor - G protein complexes | 126 | 15 | 9 | 3 | 1 | 2 | 1 | 157 |
Active-state receptors* | 130 | 15 | 9 | 6 | 1 | 2 | 1 | 164 |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2023-08-16.
Structural coverage of GPCR Classes
Receptor names:
Class A
(Rhodopsin)
Structure state frequency (from low to high)
Structure state
○ Active ○ Intermediate ○ Inactive
○ Active ○ Intermediate ○ Inactive