The four dots depict Arrestin coupling.
Receptor names:
Arrestin complexes
⬤ β-Arrestin1 ⬤ β-Arrestin2 ⬤ Arrestin-C ⬤ S-Arrestin
⬤ β-Arrestin1 ⬤ β-Arrestin2 ⬤ Arrestin-C ⬤ S-Arrestin
Class A
(Rhodopsin)
Class A
Orphans
Class B1
(Secretin)
Class B2
(Adhesion)
Class C
(Glutamate)
Class F
(Frizzled)
Class T
(Taste 2)
References
Selectivity Landscape of 100 Therapeutically Relevant GPCR Profiled by an Effector Translocation-Based BRET Platform.
Avet, C., Mancini, A., Breton, B., Gouill, C. L., Hauser, A. S., Normand, C., Kobayashi, H., Gross, F., Hogue, M., Lukasheva, V., Morissette, S., Fauman, E., Fortin, J.-P., Schann, S., Leroy, X., Gloriam, D. E. & Bouvier, M.
bioRxiv 2020.04.20.052027 (2020). doi: 10.1101/2020.04.20.052027