Number of G protein structures

Structures Gs Gi/o Gq/11 G12/13 GPa1 Total
Non complexed G protein 32 80 12 6 - 130
Receptor - G protein complexes 369 422 123 11 1 926
Total structures 401 502 135 17 1 1056


Number of GPCR-G protein structures (distinct complexes)

Receptor Class Gs Gi/o Gq/11 G12/13 GPa1 Total
Class A 232 (49) 382 (124) 113 (49) 3 (3) - 730 (225)
Class B1 116 (15) 2 (2) 1 (1) - - 119 (18)
Class B2 14 (7) 6 (3) 4 (3) 8 (7) - 32 (20)
Class C 1 (1) 12 (6) 4 (1) - - 17 (8)
Class D1 - - - - 1 (1) 1 (1)
Class F 4 (3) 5 (1) 1 (1) - - 10 (5)
Class T2 - 15 (3) - - - 15 (3)


Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2024-09-25.


Structural coverage of GPCR-G protein complexes.


Receptor names:


Class A
(Rhodopsin)


G Protein complexes
s i/o q/11 12/13 GPa1




Class A
Orphans

Class B1
(Secretin)

Class B2
(Adhesion)




Class C
(Glutamate)

Class F
(Frizzled)

Class T
(Taste 2)