Number of G protein structures
Structures | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Non complexed G protein | 25 | 90 | 9 | 6 | - | 130 |
Receptor - G protein complexes | 81 | 55 | 5 | - | 1 | 142 |
Total structures | 106 | 145 | 14 | 6 | 1 | 272 |
Number of GPCR-G protein structures (distinct complexes)
Receptor Class | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Class A | 37 (13) | 43 (22) | 5 (4) | - | - | 85 (39) |
Class B1 | 43 (14) | 1 (1) | - | - | - | 44 (15) |
Class B2 | - | 2 (1) | - | - | - | 2 (1) |
Class C | - | 4 (3) | - | - | - | 4 (3) |
Class D1 | - | - | - | - | 1 (1) | 1 (1) |
Class F | 1 (1) | 5 (1) | - | - | - | 6 (2) |
Class T2 | - | - | - | - | - | 0 (0) |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2021-08-25.
Structural coverage of GPCR-G protein complexes. The five dots depict G protein complex structure presence.
Receptor names:
⬤ Gαs
⬤ Gαi/o
⬤ Gαq/11
⬤ Gα12/13
⬤ GPa1