Number of G protein structures

Structures Gs Gi/o Gq/11 G12/13 GPa1 Total
Non complexed G protein 31 81 12 6 - 130
Receptor - G protein complexes 269 316 90 9 1 685
Total structures 300 397 102 15 1 815


Number of GPCR-G protein structures (distinct complexes)

Receptor Class Gs Gi/o Gq/11 G12/13 GPa1 Total
Class A 143 (40) 293 (100) 84 (39) 2 (2) - 522 (181)
Class B1 109 (15) 2 (2) 1 (1) - - 112 (18)
Class B2 14 (7) 6 (3) 4 (3) 7 (7) - 31 (20)
Class C - 7 (3) 1 (1) - - 8 (4)
Class D1 - - - - 1 (1) 1 (1)
Class F 1 (1) 5 (1) - - - 6 (2)
Class T2 - 3 (1) - - - 3 (1)


Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2024-01-10.


Structural coverage of GPCR-G protein complexes.


Receptor names:


Class A
(Rhodopsin)


G Protein complexes
s i/o q/11 12/13 GPa1




Class A
Orphans

Class B1
(Secretin)

Class B2
(Adhesion)




Class C
(Glutamate)

Class F
(Frizzled)

Class T
(Taste 2)