Number of G protein structures
Structures | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Non complexed G protein | 29 | 77 | 10 | 6 | - | 122 |
Receptor - G protein complexes | 228 | 265 | 81 | 9 | 1 | 584 |
Total structures | 257 | 342 | 91 | 15 | 1 | 706 |
Number of GPCR-G protein structures (distinct complexes)
Receptor Class | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Class A | 113 (35) | 242 (90) | 76 (36) | 2 (2) | - | 433 (163) |
Class B1 | 100 (15) | 2 (2) | 1 (1) | - | - | 103 (18) |
Class B2 | 14 (7) | 6 (3) | 4 (3) | 7 (7) | - | 31 (20) |
Class C | - | 7 (3) | - | - | - | 7 (3) |
Class D1 | - | - | - | - | 1 (1) | 1 (1) |
Class F | 1 (1) | 5 (1) | - | - | - | 6 (2) |
Class T2 | - | 3 (1) | - | - | - | 3 (1) |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2023-08-16.
Structural coverage of GPCR-G protein complexes.
Receptor names:
Class A
(Rhodopsin)
G Protein complexes
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1