Number of G protein structures
Structures | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Non complexed G protein | 31 | 81 | 12 | 6 | - | 130 |
Receptor - G protein complexes | 269 | 316 | 90 | 9 | 1 | 685 |
Total structures | 300 | 397 | 102 | 15 | 1 | 815 |
Number of GPCR-G protein structures (distinct complexes)
Receptor Class | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Class A | 143 (40) | 293 (100) | 84 (39) | 2 (2) | - | 522 (181) |
Class B1 | 109 (15) | 2 (2) | 1 (1) | - | - | 112 (18) |
Class B2 | 14 (7) | 6 (3) | 4 (3) | 7 (7) | - | 31 (20) |
Class C | - | 7 (3) | 1 (1) | - | - | 8 (4) |
Class D1 | - | - | - | - | 1 (1) | 1 (1) |
Class F | 1 (1) | 5 (1) | - | - | - | 6 (2) |
Class T2 | - | 3 (1) | - | - | - | 3 (1) |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2024-01-10.
Structural coverage of GPCR-G protein complexes.
Receptor names:
Class A
(Rhodopsin)
G Protein complexes
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1