Number of G protein structures
Structures | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Non complexed G protein | 32 | 80 | 12 | 6 | - | 130 |
Receptor - G protein complexes | 369 | 422 | 123 | 11 | 1 | 926 |
Total structures | 401 | 502 | 135 | 17 | 1 | 1056 |
Number of GPCR-G protein structures (distinct complexes)
Receptor Class | Gs | Gi/o | Gq/11 | G12/13 | GPa1 | Total |
Class A | 232 (49) | 382 (124) | 113 (49) | 3 (3) | - | 730 (225) |
Class B1 | 116 (15) | 2 (2) | 1 (1) | - | - | 119 (18) |
Class B2 | 14 (7) | 6 (3) | 4 (3) | 8 (7) | - | 32 (20) |
Class C | 1 (1) | 12 (6) | 4 (1) | - | - | 17 (8) |
Class D1 | - | - | - | - | 1 (1) | 1 (1) |
Class F | 4 (3) | 5 (1) | 1 (1) | - | - | 10 (5) |
Class T2 | - | 15 (3) | - | - | - | 15 (3) |
Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2024-09-25.
Structural coverage of GPCR-G protein complexes.
Receptor names:
Class A
(Rhodopsin)
G Protein complexes
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1
⬤ Gαs ⬤ Gαi/o ⬤ Gαq/11 ⬤ Gα12/13 ⬤ GPa1