Mutations

Position
GRM5 mGlu5 GRM5 Human 1x35 579 TM1 E A thermostabilising 9HC0, 5CGC, 9HC3, 6FFI, 4OO9, 5CGD, 6FFH, 7P2L
GRM5 mGlu5 GRM5 Human 3x48 667 TM3 N Y thermostabilising 9HC0, 5CGC, 9HC3, 6FFI, 4OO9, 5CGD, 6FFH, 7P2L
GRM5 mGlu5 GRM5 Human 3x50 669 TM3 I A thermostabilising 9HC0, 5CGC, 9HC3, 6FFI, 4OO9, 5CGD, 6FFH, 7P2L
GRM5 mGlu5 GRM5 Human 675 ICL2 G M thermostabilising 9HC0, 5CGC, 9HC3, 6FFI, 4OO9, 5CGD, 6FFH, 7P2L
GRM5 mGlu5 GRM5 Human 5x42 742 TM5 T A thermostabilising 9HC0, 5CGC, 7P2L, 9HC3, 6FFI, 8X0D, 4OO9, 7FD9, 8X0H, 8X0E, 8X0G, 8X0B, 5CGD, 6FFH, 8X0F, 8X0C, 7FD8
GRM5 mGlu5 GRM5 Human 5x53 753 TM5 S A thermostabilising 9HC0, 5CGC, 7P2L, 9HC3, 6FFI, 8X0D, 4OO9, 7FD9, 8X0H, 8X0E, 8X0G, 8X0B, 5CGD, 6FFH, 8X0F, 8X0C, 7FD8
P2Y12 P2Y12 P2RY12 Human 7x49 294 TM7 D N thermostabilising, receptor-expression 7PP1, 4NTJ, 4PXZ, 4PY0
ADRB2 β2 ADRB2 Human 187 ECL2 N E glycosylation-site 8GG9, 8GFZ, 2RH1, 8GG7, 8GG5, 9W3F, 8UO4, 6PS0, 8GED, 6PS6, 8GGP, 8UNZ, 8GGS, 8GEE, 3P0G, 3KJ6, 8GG6, 8GGR, 8GEB, 8GEH, 8GEA, 8UNL, 8GGC, 9RKF, 8UNU, 9RKG, 7XK9, 8GGN, 8GEF, 4GBR, 8UO1, 8GGM, 6E67, 8GH0, 5D5A, 8UNX, 8GE7, 5D5B, 7XKA, 8GGX, 8GGK, 9RKI, 7DHR, 8GGU, 6PS2, 7DHI, 8GE8, 3D4S, 8GFV, 8GGW, 9BUY, 3PDS, 6NI3, 8GFY, 5X7D, 8GG3, 8UNV, 6PS1, 8GG8, 8GGE, 8GEJ, 9RKH, 8GE3, 8GE2, 8GG0, 9CHX, 3NYA, 9CHV, 8JJ8, 6PS4, 4LDL, 8GGV, 8UNN, 8GGI, 8W1V, 8GGB, 8GGY, 6PRZ, 8GDZ, 8JJL, 8UNQ, 8GGA, 8GG4, 4LDO, 6OBA, 8UNS, 4QKX, 6PS3, 8GEC, 8GH1, 8GGF, 8GFX, 8UNT, 8GGL, 8UNY, 8GE4, 3NY8, 8JJO, 8GEI, 5D6L, 6PS5, 8GFW, 8GGJ, 8GE9, 8UNM, 8GG1, 4LDE, 5JQH, 8GE5, 8UNR, 3SN6, 8GEG, 8UNW, 8GE1, 8UNP, 8GGQ, 3NY9, 8UO2, 8GGZ, 8GGO, 8UO3, 8GG2, 6N48, 8UO0, 6MXT, 9CHU, 8UNO, 8GE6, 8GGT
AA2AR A2A ADORA2A Human 2x52 54 TM2 A L thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 4UHR, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 4UG2, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 2YDO, 5IUB, 5NLX, 5N2R, 2YDV, 3UZA
AA2AR A2A ADORA2A Human 3x36 88 TM3 T A thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 5IUB, 5NLX, 5N2R, 3UZA
AA2AR A2A ADORA2A Human 3x55 107 TM3 R A thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 5IUB, 5NLX, 5N2R, 3UZA
AA2AR A2A ADORA2A Human 4x43 122 TM4 K A thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 5IUB, 5NLX, 5N2R, 3UZA
AA2AR A2A ADORA2A Human 154 ECL2 N A glycosylation-site 5MZJ, 5MZP, 5NM4, 5G53, 4UHR, 5OLZ, 5IUA, 5IU7, 5NM2, 6GDG, 5IU4, 4UG2, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 2YDO, 5IUB, 5NLX, 5N2R, 2YDV
AA2AR A2A ADORA2A Human 5x63 202 TM5 L A thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 5IUB, 5NLX, 5N2R, 3UZA
AA2AR A2A ADORA2A Human 6x37 235 TM6 L A thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 5IUB, 5NLX, 5N2R, 3UZA
AA2AR A2A ADORA2A Human 6x41 239 TM6 V A thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 5IUB, 5NLX, 5N2R, 3UZA
AA2AR A2A ADORA2A Human 7x41 277 TM7 S A thermostabilising 5MZJ, 5MZP, 5NM4, 3REY, 5OLZ, 5IUA, 3RFM, 5IU7, 3PWH, 5NM2, 5IU4, 5OLV, 5OM1, 5IU8, 5OLH, 5OM4, 5OLO, 5OLG, 3UZC, 5IUB, 5NLX, 5N2R, 3UZA
ADRB1 β1 ADRB1 Wild turkey 1x59 68 TM1 R S thermostabilising 4BVN, 3ZPQ, 5F8U, 3ZPR, 2Y04, 6IBL, 2YCZ, 6H7J, 6H7O, 2YCX, 6H7M, 4AMI, 4AMJ, 2Y00, 2VT4, 6H7N, 2Y01, 2Y03, 6H7L, 2YCW, 2Y02, 4GPO, 2YCY, 5A8E
ADRB1 β1 ADRB1 Wild turkey 2x53 90 TM2 M V thermostabilising 4BVN, 3ZPQ, 5F8U, 3ZPR, 2Y04, 6IBL, 2YCZ, 6H7J, 6H7O, 2YCX, 6H7M, 4AMI, 4AMJ, 2Y00, 2VT4, 6H7N, 2Y01, 6TKO, 2Y03, 6H7L, 2YCW, 2Y02, 4GPO, 2YCY, 5A8E
ADRB1 β1 ADRB1 Wild turkey 3x27 116 TM3 C L receptor-expression 4BVN, 3ZPQ, 5F8U, 3ZPR, 2Y04, 6IBL, 2YCZ, 6H7J, 6H7O, 2YCX, 6H7M, 4AMI, 4AMJ, 2Y00, 2VT4, 6H7N, 2Y01, 6TKO, 2Y03, 6H7L, 2YCW, 2Y02, 4GPO, 2YCY, 5A8E
ADRB1 β1 ADRB1 Wild turkey 5x58 227 TM5 Y A thermostabilising 4BVN, 4AMI, 3ZPQ, 4AMJ, 2YCW, 2Y02, 2YCZ, 4GPO, 2Y00, 2VT4, 5F8U, 2YCY, 2Y01, 2Y03, 3ZPR, 2YCX, 5A8E, 2Y04
ADRB1 β1 ADRB1 Wild turkey 6x27 282 TM6 A L thermostabilising 4BVN, 4AMI, 3ZPQ, 4AMJ, 2YCW, 2Y02, 2YCZ, 4GPO, 2Y00, 2VT4, 5F8U, 2YCY, 2Y01, 2Y03, 3ZPR, 2YCX, 5A8E, 2Y04
ADRB1 β1 ADRB1 Wild turkey 7x36 327 TM7 F A thermostabilising 4BVN, 3ZPQ, 5F8U, 3ZPR, 2Y04, 6IBL, 2YCZ, 6H7J, 6H7O, 2YCX, 6H7M, 4AMI, 4AMJ, 2Y00, 2VT4, 6H7N, 2Y01, 6TKO, 2Y03, 6H7L, 2YCW, 2Y02, 4GPO, 2YCY, 5A8E
ADRB1 β1 ADRB1 Wild turkey 7x48 338 TM7 F M thermostabilising 4BVN, 3ZPQ, 5F8U, 3ZPR, 2Y04, 6IBL, 2YCZ, 6H7J, 6H7O, 2YCX, 6H7M, 4AMI, 4AMJ, 2Y00, 2VT4, 6H7N, 2Y01, 6TKO, 2Y03, 6H7L, 2YCW, 2Y02, 4GPO, 2YCY, 5A8E
ADRB1 β1 ADRB1 Wild turkey 8x59 358 H8 C A palmitoylation-site 4BVN, 3ZPQ, 5F8U, 3ZPR, 2Y04, 6IBL, 2YCZ, 6H7J, 6H7O, 2YCX, 6H7M, 4AMI, 4AMJ, 2Y00, 2VT4, 6H7N, 2Y01, 2Y03, 6H7L, 2YCW, 2Y02, 4GPO, 2YCY, 5A8E
AA1R A1 ADORA1 Human 2x52 57 TM2 A L thermostabilising 5N2S
AA1R A1 ADORA1 Human 3x36 91 TM3 T A thermostabilising 5N2S
AA1R A1 ADORA1 Human 159 ECL2 N A glycosylation-site 5UEN, 5N2S
AA1R A1 ADORA1 Human 5x63 205 TM5 Y A thermostabilising 5N2S
AA1R A1 ADORA1 Human 6x37 236 TM6 L A thermostabilising 5N2S
AA1R A1 ADORA1 Human 6x41 240 TM6 L A thermostabilising 5N2S
AA1R A1 ADORA1 Human 7x41 277 TM7 T A thermostabilising 5N2S
AA1R A1 ADORA1 Human 8x64 309 H8 C S palmitoylation-site 5N2S
CCR5 CCR5 CCR5 Human 1x60 58 TM1 C Y thermostabilising 4MBS, 5UIW, 7F1T, 6AKY, 6AKX
CCR5 CCR5 CCR5 Human 4x61 163 TM4 G N thermostabilising 7F1R, 5UIW, 4MBS, 7F1T, 7F1S, 6AKY, 6AKX, 7F1Q
CCR5 CCR5 CCR5 Human 6x33 233 TM6 A D thermostabilising, receptor-salt-bridge 4MBS, 5UIW, 7F1T, 6AKY, 6AKX
CCR5 CCR5 CCR5 Human 8x49 303 H8 K E thermostabilising 4MBS, 5UIW, 7F1T, 6AKY, 6AKX
NTR1 NTS1 Ntsr1 Rat 1x54 86 TM1 A L thermostabilising 8FN1, 4BWB, 6ZIN, 6Z4Q, 4BV0, 6Z66, 6Z4S, 6Z8N, 4XES, 9QD4, 4BUO, 7L0P, 7L0S, 8FN0, 7L0Q, 6YVR, 3ZEV, 6ZA8, 7L0R, 9QC1, 4XEE, 6Z4V, 5T04, 4GRV, 8FMZ
5HT2C 5-HT2C HTR2C Human 7x45 360 TM7 C N thermostabilising, receptor-expression 6BQH, 6BQG
5HT2B 5-HT2B HTR2B Human 3x41 144 TM3 M W thermostabilising 6DRZ, 6DRY, 7SRQ, 4IB4, 7SRR, 5TUD, 4NC3, 6DRX, 9JGK, 6DS0, 5TVN
OPRK κ OPRK1 Human 3x29 135 TM3 I L receptor-expression 9PA1, 9ZZO, 6B73, 8DZP, 4DJH, 9PA6, 8DZQ, 7Y1F, 9W49, 6VI4, 8DZS, 9PA4, 9V6O, 8FEG, 7YIT, 8DZR
Q9WTK1 BLT1 LTB4R Guinea pig 2x67 83 TM2 H G thermostabilising 5X33
Q9WTK1 BLT1 LTB4R Guinea pig 3x21 88 TM3 K G thermostabilising 5X33
Q9WTK1 BLT1 LTB4R Guinea pig 5x67 212 TM5 V A thermostabilising 5X33
Q9WTK1 BLT1 LTB4R Guinea pig 309 C-term S A thermostabilising 5X33
PTAFR PAF PTAFR Human 3x51 116 TM3 F Y receptor-expression 5ZKP, 5ZKQ
PTAFR PAF PTAFR Human 169 ECL2 N D glycosylation-site 5ZKP, 5ZKQ
PTAFR PAF PTAFR Human 6x34 230 TM6 A D thermostabilising 5ZKP, 5ZKQ
PTAFR PAF PTAFR Human 6x38 234 TM6 V A receptor-expression 5ZKP, 5ZKQ
PTAFR PAF PTAFR Human 7x49 289 TM7 D N receptor-expression 5ZKP, 5ZKQ
5HT1B 5-HT1B HTR1B Human 3x41 138 TM3 L W thermostabilising 4IAQ, 4IAR, 6G79, 7C61, 5V54
ADRB2 β2 ADRB2 Human 16 N-term G R other-effect 5X7D, 2RH1, 3NY8, 3P0G, 3D4S, 3KJ6, 3NY9, 5D6L, 2R4R, 3NYA, 5D5A, 5D5B
ADRB2 β2 ADRB2 Human 1x26 27 TM1 E Q other-effect 5X7D, 2RH1, 2R4S, 3NY8, 3P0G, 3D4S, 3KJ6, 5D5B, 3NY9, 5D6L, 3NYA, 2R4R, 5D5A, 3PDS
ACM2 M2 CHRM2 Human 6 N-term N D glycosylation-site 7T8X, 6OIK, 4MQT, 3UON, 7T94, 7T90, 4MQS, 7T96
ACM2 M2 CHRM2 Human 9 N-term N D glycosylation-site 7T8X, 6OIK, 4MQT, 3UON, 7T94, 7T90, 4MQS, 7T96
OPSD Rhodopsin RHO Human 2 N-term N C other-effect, thermostabilising, receptor-disulfide-bridge 4ZWJ, 5W0P, 5DGY
OPSD Rhodopsin RHO Human 3x28 113 TM3 E Q thermostabilising 6CMO, 4ZWJ, 5W0P, 5DGY
OPSD Rhodopsin RHO Human 6x40 257 TM6 M Y thermostabilising 6CMO, 4ZWJ, 5W0P, 5DGY
OPSD Rhodopsin RHO Human 282 ECL3 N C thermostabilising, receptor-disulfide-bridge 6CMO, 4ZWJ, 5W0P, 5DGY
AA2AR A2A ADORA2A Human 2x46 48 TM2 L A thermostabilising 2YDV, 4UHR, 2YDO, 4UG2
AA2AR A2A ADORA2A Human 2x62 65 TM2 T A thermostabilising 2YDV, 4UHR, 2YDO, 4UG2
AA2AR A2A ADORA2A Human 3x37 89 TM3 Q A thermostabilising 2YDV, 4UHR, 2YDO, 4UG2
ADRB2 β2 ADRB2 Human 2x66 96 TM2 M T receptor-expression 4LDL, 4GBR, 4LDE, 5JQH, 4LDO, 4QKX, 3SN6
ADRB2 β2 ADRB2 Human 23x49 98 ECL1 M T receptor-expression 4LDL, 4GBR, 4LDE, 5JQH, 4LDO, 4QKX, 3SN6
ADRB2 β2 ADRB2 Human 6x27 265 TM6 C A other-effect 4LDL, 4LDE, 5JQH, 4LDO, 4QKX
NPY1R Y1 NPY1R Human 3x41 129 TM3 F W thermostabilising 5ZBQ, 5ZBH
SMO SMO SMO Human 194 N-term E M receptor-expression 5V56
NTR1 NTS1 Ntsr1 Rat 3x49 166 TM3 E A thermostabilising 4GRV, 4XES
NTR1 NTS1 Ntsr1 Rat 215 ECL2 G A thermostabilising 5T04, 4GRV, 4XES, 4XEE
NTR1 NTS1 Ntsr1 Rat 6x37 310 TM6 L A thermostabilising 4GRV
NTR1 NTS1 Ntsr1 Rat 7x41 358 TM7 F A receptor-expression 5T04, 4GRV
NTR1 NTS1 Ntsr1 Rat 7x43 360 TM7 V A thermostabilising 5T04, 4GRV, 4XES, 4XEE
ADRB2 β2 ADRB2 Human 2x63 93 TM2 H C thermostabilising, receptor-ligand-bond 4QKX, 3PDS
AA2AR A2A ADORA2A Human 154 ECL2 N Q glycosylation-site 3VG9, 3VGA
ACM2 M2 CHRM2 Human 2 N-term N D glycosylation-site 3UON, 4MQS, 4MQT
ACM2 M2 CHRM2 Human 3 N-term N D glycosylation-site 3UON, 4MQS, 4MQT, 6OIK
ADRB2 β2 ADRB2 Human 3x41 122 TM3 E W thermostabilising, receptor-expression 3NY8, 3NY9, 3D4S, 3NYA
FFAR1 FFA1 FFAR1 Human 2x40 42 TM2 L A thermostabilising 5TZY, 5KW2, 4PHU, 5TZR
FFAR1 FFA1 FFAR1 Human 3x34 88 TM3 F A thermostabilising 5KW2, 4PHU, 5TZR
FFAR1 FFA1 FFAR1 Human 3x49 103 TM3 G A thermostabilising 5TZY, 5KW2, 4PHU, 5TZR
FFAR1 FFA1 FFAR1 Human 5x58 202 TM5 Y F thermostabilising 5TZY, 5KW2, 4PHU, 5TZR
OX1R OX1 HCRTR1 Human 6x56 319 TM6 V I other-effect 4ZJ8, 4ZJC, 6V9S
APJ apelin APLNR Human 3x40 117 TM3 V A thermostabilising 5VBL
APJ apelin APLNR Human 177 ECL2 T N glycosylation-site 5VBL
APJ apelin APLNR Human 6x48 261 TM6 W K thermostabilising 5VBL
APJ apelin APLNR Human 8x59 325 H8 C L palmitoylation-site 5VBL
APJ apelin APLNR Human 8x60 326 H8 C M palmitoylation-site 5VBL
OPSD Rhodopsin RHO Bovine 2 N-term N C thermostabilising, receptor-disulfide-bridge 4BEY, 6FK7, 6FKB, 5EN0, 2J4Y, 6FKA, 6FKC, 4BEZ, 6FK9, 3C9M, 5DYS, 6FK6, 6FKD, 6FK8, 4A4M, 2X72
OPSD Rhodopsin RHO Bovine 6x40 257 TM6 M Y thermostabilising 4A4M
OPSD Rhodopsin RHO Bovine 282 ECL3 D C thermostabilising, receptor-disulfide-bridge 4BEY, 6FK7, 6FKB, 5EN0, 2J4Y, 6FKA, 6FKC, 4BEZ, 6FK9, 3C9M, 5DYS, 6FK6, 6FKD, 6FK8, 4A4M, 2X72
ACM2 M2 CHRM2 Human 373 ICL3 A T other-effect 4MQS, 4MQT
ACM2 M2 CHRM2 Human 374 ICL3 K R other-effect 4MQS, 4MQT
ACM1 M1 CHRM1 Human 2 N-term N Q glycosylation-site 6OIJ, 6WJC, 5CXV
ACM1 M1 CHRM1 Human 12 N-term N Q glycosylation-site 6OIJ, 6WJC, 5CXV
ACM1 M1 CHRM1 Human 3x37 110 TM3 N Q glycosylation-site 6OIJ, 6WJC, 5CXV
GLP1R GLP-1 GLP1R Human 2x56 193 TM2 S C thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 2x59 196 TM2 I F thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 3x24 225 TM3 S A thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 3x32 233 TM3 M C thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 4x48 271 TM4 S A thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 5x51 317 TM5 I C thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 5x52 318 TM5 G I thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 6x30 346 TM6 K A thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 6x31 347 TM6 C F thermostabilising 5VEW, 5VEX
GLP1R GLP-1 GLP1R Human 6x45 361 TM6 G C thermostabilising 5VEW, 5VEX
NTR1 NTS1 Ntsr1 Rat 2x40 103 TM2 H D receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 2x42 105 TM2 H Y receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 3x44 161 TM3 A V receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 3x50 167 TM3 R L receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 213 ECL2 R L receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 5x36 234 TM5 V L receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 5x54 253 TM5 I A thermostabilising 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 6x32 305 TM6 H R receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 7x41 358 TM7 F V receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 7x46 362 TM7 S A receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
SMO SMO SMO Human 3x40 329 TM3 V F thermostabilising, receptor-expression 5L7D, 5L7I
GLR glucagon GCGR Human 2x39 173 TM2 R A thermostabilising 5EE7, 5YQZ
G1SGD4 GLP-1 GLP1R Rabbit 106 N-term T A other-effect 5VAI
G1SGD4 GLP-1 GLP1R Rabbit 112 N-term H P other-effect 5VAI
G1SGD4 GLP-1 GLP1R Rabbit 1x31 140 TM1 Q R other-effect 5VAI
EDNRB ETB EDNRB Human 1x55 124 TM1 R Y thermostabilising 5XPR, 5X93
EDNRB ETB EDNRB Human 2x56 154 TM2 D A thermostabilising 5X93
EDNRB ETB EDNRB Human 5x36 270 TM5 K A thermostabilising 5XPR, 5X93
EDNRB ETB EDNRB Human 6x54 342 TM6 S A thermostabilising 5XPR, 5X93
EDNRB ETB EDNRB Human 7x48 381 TM7 I A thermostabilising 5XPR, 5X93
EDNRB ETB EDNRB Human 8x53 396 H8 C A palmitoylation-site 5XPR, 5X93
EDNRB ETB EDNRB Human 8x57 400 H8 C A palmitoylation-site 5XPR, 5X93
EDNRB ETB EDNRB Human 405 C-term C A palmitoylation-site 5XPR, 5X93
CXCR4 CXCR4 CXCR4 Human 3x41 125 TM3 L W thermostabilising 3ODU, 3OE0, 8ZPL, 8ZPM, 4RWS, 3OE6, 3OE8, 3OE9, 8ZPN
OPRD δ OPRD1 Human 37 N-term P S other-effect 4N6H
GLP1R GLP-1 GLP1R Human 207 ECL1 T E thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 211 ECL1 Q A thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 215 ECL1 D R thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 3x31 232 TM3 L F thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 260 ICL2 L F other-effect, thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 295 ECL2 G A thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 45x52 298 ECL2 T A thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 5x63 329 TM5 C A thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 6x42 358 TM6 P A thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 6x45 361 TM6 G A thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 6x47 363 TM6 H V thermostabilising 5NX2
GLP1R GLP-1 GLP1R Human 7x56 405 TM7 V A thermostabilising 5NX2
GLR glucagon GCGR Human 1x48 154 TM1 G A thermostabilising 5EE7
GLR glucagon GCGR Human 2x48 182 TM2 A L thermostabilising 5EE7
GLR glucagon GCGR Human 2x56 190 TM2 S A thermostabilising 5EE7
GLR glucagon GCGR Human 2x59 193 TM2 V F thermostabilising 5EE7
GLR glucagon GCGR Human 207 ECL1 G E thermostabilising 5EE7
GLR glucagon GCGR Human 3x24 223 TM3 G A thermostabilising 5EE7
GLR glucagon GCGR Human 4x54 276 TM4 M A thermostabilising 5EE7
GLR glucagon GCGR Human 6x30 344 TM6 K A thermostabilising 5EE7
GLR glucagon GCGR Human 6x48 362 TM6 E F thermostabilising 5EE7
GLR glucagon GCGR Human 7x39 387 TM7 F A thermostabilising 5EE7
OPSD Rhodopsin RHO Bovine 3x28 113 TM3 E Q thermostabilising 2X72
OPSD Rhodopsin RHO Bovine 2x60 94 TM2 T I thermostabilising 5DYS, 5EN0
OX2R OX2 HCRTR2 Human 6x39 308 TM6 I V other-effect 5WS3, 4S0V, 5WQC
CXCR4 CXCR4 CXCR4 Human 6x36 240 TM6 T P thermostabilising 4RWS, 3OE9, 3OE0
DRD3 D3 DRD3 Human 3x41 119 TM3 L W thermostabilising 9F34, 9F33, 3PBL
CNR1 CB1 CNR1 Human 3x46 210 TM3 T A thermostabilising 5TGZ, 5XR8, 5XRA, 5U09
CNR1 CB1 CNR1 Human 5x37 273 TM5 E K thermostabilising, receptor-expression 5TGZ, 5XR8, 5XRA
CNR1 CB1 CNR1 Human 5x47 283 TM5 T V receptor-expression 5TGZ, 5XR8, 5XRA
CNR1 CB1 CNR1 Human 6x32 340 TM6 R E thermostabilising, receptor-expression 5TGZ, 5XR8, 5XRA
NTR1 NTS1 Ntsr1 Rat 1x51 83 TM1 S G receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 2x38 101 TM2 T R receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 2x551 119 TM2 L F receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 2x57 121 TM2 M L receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 2x60 124 TM2 E D receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 2x61 125 TM2 L V receptor-expression 4BV0
NTR1 NTS1 Ntsr1 Rat 3x26 143 TM3 R K receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 3x33 150 TM3 D E receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 3x55 172 TM3 C R receptor-expression 4BV0
NTR1 NTS1 Ntsr1 Rat 34x53 177 ICL2 A H receptor-expression 4BV0
NTR1 NTS1 Ntsr1 Rat 4x65 208 TM4 M V receptor-expression 4BV0
NTR1 NTS1 Ntsr1 Rat 5x42 240 TM5 V L receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 5x63 262 TM5 N R receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 5x64 263 TM5 K R receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 6x40 313 TM6 V M receptor-expression 4BV0
NTR1 NTS1 Ntsr1 Rat 6x59 332 TM6 C V receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 7x25 342 TM7 F A receptor-expression 4BWB, 4BV0
NTR1 NTS1 Ntsr1 Rat 7x37 354 TM7 T S receptor-expression 4BWB, 4BV0
P2RY1 P2Y1 P2RY1 Human 7x49 320 TM7 D N thermostabilising, receptor-expression 4XNV, 4XNW
ADRB1 β1 ADRB1 Wild turkey 3x40 129 TM3 I V thermostabilising 4BVN, 5A8E
ADRB1 β1 ADRB1 Wild turkey 7x31 322 TM7 D K thermostabilising 4BVN
ADRB1 β1 ADRB1 Wild turkey 7x53 343 TM7 Y L thermostabilising 4BVN, 5A8E
ADRB1 β1 ADRB1 Wild turkey 3x41 130 TM3 E W thermostabilising 5A8E
DRD2 D2 DRD2 Human 3x40 122 TM3 I A thermostabilising 6CM4
DRD2 D2 DRD2 Human 6x37 375 TM6 L A thermostabilising 6CM4
DRD2 D2 DRD2 Human 6x41 379 TM6 L A thermostabilising 6CM4
CRHR1 CRF1 CRHR1 Human 2x44 156 TM2 W A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 2x48 160 TM2 S A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 4x43 228 TM4 K A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 45x52 260 ECL2 F A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 5x48 277 TM5 I A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 6x30 309 TM6 Y A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 6x51 330 TM6 F A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 7x38 349 TM7 S A thermostabilising 4K5Y, 4Z9G
CRHR1 CRF1 CRHR1 Human 7x53 363 TM7 Y A thermostabilising 4K5Y, 4Z9G
OPSD Rhodopsin RHO Japanese flying squid 18 N-term V I other-effect 2ZIY
AA2AR A2A ADORA2A Human 3x39 91 TM3 S A thermostabilising 5WF6
PAR1 PAR1 F2R Human 250 ECL2 N G glycosylation-site 3VW7
PAR1 PAR1 F2R Human 259 ECL2 N S glycosylation-site 3VW7
S1PR1 S1P1 S1PR1 Human 6x30 251 TM6 S N other-effect 3V2Y, 3V2W
S1PR1 S1P1 S1PR1 Human 6x31 252 TM6 L V other-effect 3V2Y, 3V2W
C5AR1 C5a1 C5AR1 Human 2x53 85 TM2 S A palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 2x59 91 TM2 I A palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 34x51 142 ICL2 I A palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 34x55 146 ICL2 N R palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 4x45 156 TM4 A L palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 4x62 172 TM4 F A palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 5x68 232 TM5 R A palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 234 ICL3 A E palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 8x54 311 H8 L E palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 317 C-term S E palmitoylation-site 5O9H
C5AR1 C5a1 C5AR1 Human 321 C-term N E palmitoylation-site 5O9H
PAR2 PAR2 F2RL1 Human 1x46 89 TM1 G A thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 2x37 108 TM2 H A thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 3x34 157 TM3 G A thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 3x43 166 TM3 M L thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 3x51 174 TM3 Y A thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 3x53 176 TM3 V E thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 222 ECL2 N Q glycosylation-site 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 5x64 268 TM5 M A thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 6x38 289 TM6 I A thermostabilising 5NDD, 5NJ6, 5NDZ
PAR2 PAR2 F2RL1 Human 6x42 293 TM6 L A thermostabilising 5NDD, 5NJ6, 5NDZ
AA2AR A2A ADORA2A Human 2x50 52 TM2 D N thermostabilising 5WF5
C5AR1 C5a1 C5AR1 Human 34x53 144 ICL2 C X 6C1Q, 6C1R
OPSD Rhodopsin RHO Bovine 2x56 90 TM2 G D natural-mutation-snp-incl-disease-causing 4BEY, 4BEZ
NTR1 NTS1 Ntsr1 Rat 5x37 235 TM5 K R receptor-expression 4BWB
NTR1 NTS1 Ntsr1 Rat 5x61 260 TM5 I A receptor-expression 4BWB
LPAR1 LPA1 LPAR1 Human 5x37 204 TM5 D C thermostabilising, receptor-disulfide-bridge 4Z36
LPAR1 LPA1 LPAR1 Human 6x59 282 TM6 V C thermostabilising, receptor-disulfide-bridge 4Z36
OPSD Rhodopsin RHO Human 336 C-term T X phosphorylation-site 5W0P
OPSD Rhodopsin RHO Human 338 C-term S X phosphorylation-site 5W0P
CCR9 CCR9 CCR9 Human 34 N-term T E glycosylation-site 5LWE
CCR9 CCR9 CCR9 Human 12x48 77 ICL1 T A thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 12x50 79 ICL1 V A thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 2x38 82 TM2 M A thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 3x47 141 TM3 S C thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 5x41 216 TM5 T A thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 6x36 255 TM6 V A thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 7x29 294 TM7 N A thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 7x39 304 TM7 T A thermostabilising 5LWE
CCR9 CCR9 CCR9 Human 8x63 337 H8 C A palmitoylation-site 5LWE
CXCR4 CXCR4 CXCR4 Human 45x51 187 ECL2 D C thermostabilising, receptor-ligand-bond 4RWS