GPCRdb

			Position
CCR5	CCR5	4x61	163	TM4	G	N	thermostabilising	6AKX, 5UIW, 7F1R, 6AKY, 7F1Q, 7F1T, 4MBS, 7F1S
DRD2	D₂	3x40	122	TM3	I	A	thermostabilising	6CM4
DRD2	D₂	6x37	375	TM6	L	A	thermostabilising	6CM4
DRD2	D₂	6x41	379	TM6	L	A	thermostabilising	6CM4
Q9WTK1	BLT₁	2x67	83	TM2	H	G	thermostabilising	5X33
Q9WTK1	BLT₁	3x21	88	TM3	K	G	thermostabilising	5X33
Q9WTK1	BLT₁	5x67	212	TM5	V	A	thermostabilising	5X33
Q9WTK1	BLT₁		309	C-term	S	A	thermostabilising	5X33
NTR1	NTS₁	1x54	86	TM1	A	L	thermostabilising	4BV0, 5T04, 7L0R, 3ZEV, 7L0Q, 4BUO, 4BWB, 7L0S, 4XES, 4GRV, 7L0P, 4XEE
NTR1	NTS₁	2x40	103	TM2	H	D	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	2x42	105	TM2	H	Y	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	3x44	161	TM3	A	V	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	3x50	167	TM3	R	L	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁		213	ECL2	R	L	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	5x36	234	TM5	V	L	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	5x54	253	TM5	I	A	thermostabilising	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	6x32	305	TM6	H	R	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	7x41	358	TM7	F	V	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
NTR1	NTS₁	7x46	362	TM7	S	A	receptor-expression	3ZEV, 4BV0, 4BUO, 4BWB
5HT1B	5-HT_1B	3x41	138	TM3	L	W	thermostabilising	7C61, 4IAQ, 6G79, 5V54, 4IAR
S1PR1	S1P₁	6x30	251	TM6	S	N	other-effect	3V2W, 3V2Y
S1PR1	S1P₁	6x31	252	TM6	L	V	other-effect	3V2W, 3V2Y
C5AR1	C5a₁	2x53	85	TM2	S	A	palmitoylation-site	5O9H
C5AR1	C5a₁	2x59	91	TM2	I	A	palmitoylation-site	5O9H
C5AR1	C5a₁	34x51	142	ICL2	I	A	palmitoylation-site	5O9H
C5AR1	C5a₁	34x55	146	ICL2	N	R	palmitoylation-site	5O9H
C5AR1	C5a₁	4x45	156	TM4	A	L	palmitoylation-site	5O9H
C5AR1	C5a₁	4x62	172	TM4	F	A	palmitoylation-site	5O9H
C5AR1	C5a₁	5x68	232	TM5	R	A	palmitoylation-site	5O9H
C5AR1	C5a₁		234	ICL3	A	E	palmitoylation-site	5O9H
C5AR1	C5a₁		311	C-term	L	E	palmitoylation-site	5O9H
C5AR1	C5a₁		317	C-term	S	E	palmitoylation-site	5O9H
C5AR1	C5a₁		321	C-term	N	E	palmitoylation-site	5O9H
ADRB1	β₁	1x59	68	TM1	R	S	thermostabilising	6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O
ADRB1	β₁	2x53	90	TM2	M	V	thermostabilising	6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO
ADRB1	β₁	3x27	116	TM3	C	L	receptor-expression	6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO
ADRB1	β₁	5x58	227	TM5	Y	A	thermostabilising	2Y00, 3ZPQ, 2Y04, 2Y02, 4AMI, 2YCX, 2YCW, 5F8U, 2Y03, 2YCY, 2YCZ, 2VT4, 5A8E, 4BVN, 4GPO, 3ZPR, 4AMJ, 2Y01
ADRB1	β₁	6x27	282	TM6	A	L	thermostabilising	2Y00, 3ZPQ, 2Y04, 2Y02, 4AMI, 2YCX, 2YCW, 5F8U, 2Y03, 2YCY, 2YCZ, 2VT4, 5A8E, 4BVN, 4GPO, 3ZPR, 4AMJ, 2Y01
ADRB1	β₁	7x36	327	TM7	F	A	thermostabilising	6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO
ADRB1	β₁	7x48	338	TM7	F	M	thermostabilising	6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO
ADRB1	β₁	8x59	358	H8	C	A	palmitoylation-site	6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O
OPSD	Rhodopsin		2	N-term	N	C	receptor-disulfide-bridge, other-effect, thermostabilising	5W0P, 5DGY, 4ZWJ
OPSD	Rhodopsin	3x28	113	TM3	E	Q	thermostabilising	5W0P, 6CMO, 5DGY, 4ZWJ
OPSD	Rhodopsin	6x40	257	TM6	M	Y	thermostabilising	5W0P, 6CMO, 5DGY, 4ZWJ
OPSD	Rhodopsin		282	ECL3	N	C	receptor-disulfide-bridge, thermostabilising	5W0P, 6CMO, 5DGY, 4ZWJ
PTAFR	PAF	3x51	116	TM3	F	Y	receptor-expression	5ZKQ, 5ZKP
PTAFR	PAF		169	ECL2	N	D	glycosylation-site	5ZKQ, 5ZKP
PTAFR	PAF	6x34	230	TM6	A	D	thermostabilising	5ZKQ, 5ZKP
PTAFR	PAF	6x38	234	TM6	V	A	receptor-expression	5ZKQ, 5ZKP
PTAFR	PAF	7x49	289	TM7	D	N	receptor-expression	5ZKQ, 5ZKP
CRFR1	CRF₁	1x36	120	TM1	V	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	1x60	144	TM1	L	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	2x44	156	TM2	W	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	2x48	160	TM2	S	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	4x43	228	TM4	K	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	45x52	260	ECL2	F	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	5x48	277	TM5	I	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	6x30	309	TM6	Y	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	6x51	330	TM6	F	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	7x38	349	TM7	S	A	thermostabilising	4Z9G, 4K5Y
CRFR1	CRF₁	7x53	363	TM7	Y	A	thermostabilising	4Z9G, 4K5Y
5HT2B	5-HT_2B	3x41	144	TM3	M	W	thermostabilising	5TVN, 5TUD, 6DRY, 4IB4, 6DRZ, 6DS0, 6DRX, 4NC3
AA2AR	A_2A	2x52	54	TM2	A	L	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 4UHR, 3RFM, 4UG2, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 2YDV, 3UZC, 5MZP, 3UZA, 2YDO, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
AA2AR	A_2A	3x36	88	TM3	T	A	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
AA2AR	A_2A	3x55	107	TM3	R	A	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
AA2AR	A_2A	4x43	122	TM4	K	A	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
AA2AR	A_2A		154	ECL2	N	A	glycosylation-site	5IU4, 5N2R, 5OLG, 5OM1, 5G53, 5OLZ, 4UHR, 4UG2, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 2YDV, 5MZP, 2YDO, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 6GDG
AA2AR	A_2A	5x63	202	TM5	L	A	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
AA2AR	A_2A	6x37	235	TM6	L	A	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
AA2AR	A_2A	6x41	239	TM6	V	A	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
AA2AR	A_2A	7x41	277	TM7	S	A	thermostabilising	5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH
ADRB2	β₂		16	N-term	G	R	other-effect	2RH1, 3D4S, 5D6L, 3NY9, 3KJ6, 5X7D, 5D5A, 2R4R, 5D5B, 3NY8, 3P0G, 3NYA
ADRB2	β₂	1x26	27	TM1	E	Q	other-effect	2RH1, 3D4S, 3PDS, 5D6L, 3NY9, 3KJ6, 5X7D, 5D5A, 2R4S, 2R4R, 5D5B, 3NY8, 3P0G, 3NYA
ADRB2	β₂		187	ECL2	N	E	glycosylation-site	6PS3, 6NI3, 6MXT, 4GBR, 3KJ6, 6PS1, 6E67, 4LDO, 7DHI, 6PS4, 4LDL, 3P0G, 6OBA, 3SN6, 3NY9, 4LDE, 6PRZ, 3NY8, 6PS5, 7DHR, 5D5B, 3NYA, 2RH1, 3D4S, 3PDS, 5D6L, 5X7D, 5D5A, 5JQH, 4QKX, 6PS6, 6PS2, 6N48, 6PS0
NPY1R	Y₁	3x41	129	TM3	F	W	thermostabilising	5ZBQ, 5ZBH
CNR1	CB₁	3x46	210	TM3	T	A	thermostabilising	5U09, 5XR8, 5XRA, 5TGZ
CCR5	CCR5	1x60	58	TM1	C	Y	thermostabilising	6AKX, 5UIW, 6AKY, 7F1T, 4MBS
CCR5	CCR5	6x33	233	TM6	A	D	thermostabilising, receptor-salt-bridge	6AKX, 5UIW, 6AKY, 7F1T, 4MBS
CCR5	CCR5	8x49	303	H8	K	E	thermostabilising	6AKX, 5UIW, 6AKY, 7F1T, 4MBS
ADRB2	β₂	3x41	122	TM3	E	W	thermostabilising, receptor-expression	3NY9, 3NY8, 3D4S, 3NYA
OPRK	κ	3x29	135	TM3	I	L	receptor-expression	6B73, 6VI4, 4DJH
ACM1	M₁		2	N-term	N	Q	glycosylation-site	5CXV, 6OIJ, 6WJC
ACM1	M₁		12	N-term	N	Q	glycosylation-site	5CXV, 6OIJ, 6WJC
ACM1	M₁	3x37	110	TM3	N	Q	glycosylation-site	5CXV, 6OIJ, 6WJC
AA2AR	A_2A		154	ECL2	N	Q	glycosylation-site	3VG9, 3VGA
OX1R	OX₁	6x56	319	TM6	V	I	other-effect	6V9S, 4ZJC, 4ZJ8
OPSD	Rhodopsin		2	N-term	N	C	receptor-disulfide-bridge, thermostabilising	6FKC, 6FKD, 2X72, 6FKA, 6FK6, 4BEY, 5DYS, 3C9M, 6FK7, 4BEZ, 6FK8, 6FKB, 5EN0, 4A4M, 2J4Y, 6FK9
OPSD	Rhodopsin		282	ECL3	D	C	receptor-disulfide-bridge, thermostabilising	6FKC, 6FKD, 2X72, 6FKA, 6FK6, 4BEY, 5DYS, 3C9M, 6FK7, 4BEZ, 6FK8, 6FKB, 5EN0, 4A4M, 2J4Y, 6FK9
AA2AR	A_2A	2x46	48	TM2	L	A	thermostabilising	4UHR, 4UG2, 2YDO, 2YDV
AA2AR	A_2A	2x62	65	TM2	T	A	thermostabilising	4UHR, 4UG2, 2YDO, 2YDV
AA2AR	A_2A	3x37	89	TM3	Q	A	thermostabilising	4UHR, 4UG2, 2YDO, 2YDV
OX2R	OX₂	6x39	308	TM6	I	V	other-effect	5WQC, 4S0V, 5WS3
CXCR4	CXCR4	3x41	125	TM3	L	W	thermostabilising	3ODU, 4RWS, 3OE6, 3OE8, 3OE9, 3OE0
CXCR4	CXCR4	6x36	240	TM6	T	P	thermostabilising	4RWS, 3OE9, 3OE0
ACM2	M₂		3	N-term	N	D	glycosylation-site	6OIK, 4MQT, 4MQS, 3UON
ACM2	M₂		6	N-term	N	D	glycosylation-site	6OIK, 4MQT, 4MQS, 3UON
ACM2	M₂		9	N-term	N	D	glycosylation-site	6OIK, 4MQT, 4MQS, 3UON
ACM2	M₂		2	N-term	N	D	glycosylation-site	4MQT, 4MQS, 3UON
ACM2	M₂		373	ICL3	A	T	other-effect	4MQT, 4MQS
ACM2	M₂		374	ICL3	K	R	other-effect	4MQT, 4MQS
ADRB2	β₂	2x66	96	TM2	M	T	receptor-expression	3SN6, 4LDL, 5JQH, 4LDO, 4QKX, 4LDE, 4GBR
ADRB2	β₂	23x49	98	ECL1	M	T	receptor-expression	3SN6, 4LDL, 5JQH, 4LDO, 4QKX, 4LDE, 4GBR
ADRB2	β₂	6x27	265	TM6	C	A	other-effect	4LDL, 5JQH, 4LDO, 4QKX, 4LDE
ADRB2	β₂	2x63	93	TM2	H	C	receptor-ligand-bond, thermostabilising	4QKX, 3PDS
OPSD	Rhodopsin		336	C-term	T	X	phosphorylation-site	5W0P
OPSD	Rhodopsin		338	C-term	S	X	phosphorylation-site	5W0P
OPSD	Rhodopsin	3x28	113	TM3	E	Q	thermostabilising	2X72
P2RY1	P2Y₁	7x49	320	TM7	D	N	thermostabilising, receptor-expression	4XNV, 4XNW
C5AR1	C5a₁	34x53	144	ICL2	C	X		6C1R, 6C1Q
NTR1	NTS₁	3x49	166	TM3	E	A	thermostabilising	4XES, 4GRV
NTR1	NTS₁		215	ECL2	G	A	thermostabilising	4XEE, 4XES, 5T04, 4GRV
NTR1	NTS₁	6x37	310	TM6	L	A	thermostabilising	4GRV
NTR1	NTS₁	7x41	358	TM7	F	A	receptor-expression	5T04, 4GRV
NTR1	NTS₁	7x43	360	TM7	V	A	thermostabilising	4XEE, 4XES, 5T04, 4GRV
LPAR1	LPA₁	5x37	204	TM5	D	C	receptor-disulfide-bridge, thermostabilising	4Z36
LPAR1	LPA₁	6x59	282	TM6	V	C	receptor-disulfide-bridge, thermostabilising	4Z36
5HT2C	5-HT_2C	7x45	360	TM7	C	N	thermostabilising, receptor-expression	6BQH, 6BQG
P2Y12	P2Y₁₂	7x49	294	TM7	D	N	thermostabilising, receptor-expression	4PY0, 4PXZ, 4NTJ
SMO	SMO	3x40	329	TM3	V	F	thermostabilising, receptor-expression	5L7I, 5L7D
SMO	SMO		194	N-term	E	M	receptor-expression	5V56
ADRB1	β₁	3x40	129	TM3	I	V	thermostabilising	4BVN, 5A8E
ADRB1	β₁	7x31	322	TM7	D	K	thermostabilising	4BVN
ADRB1	β₁	7x53	343	TM7	Y	L	thermostabilising	4BVN, 5A8E
OPSD	Rhodopsin	6x40	257	TM6	M	Y	thermostabilising	4A4M
AA2AR	A_2A	2x50	52	TM2	D	N	thermostabilising	5WF5
AA2AR	A_2A	3x39	91	TM3	S	A	thermostabilising	5WF6
OPSD	Rhodopsin	2x60	94	TM2	T	I	thermostabilising	5EN0, 5DYS
CXCR4	CXCR4	45x51	187	ECL2	D	C	receptor-ligand-bond, thermostabilising	4RWS
GRM5	mGlu₅	1x35	579	TM1	E	A	thermostabilising	6FFH, 5CGC, 6FFI, 5CGD, 4OO9
GRM5	mGlu₅	3x48	667	TM3	N	Y	thermostabilising	6FFH, 5CGC, 6FFI, 5CGD, 4OO9
GRM5	mGlu₅	3x50	669	TM3	I	A	thermostabilising	6FFH, 5CGC, 6FFI, 5CGD, 4OO9
GRM5	mGlu₅		675	ICL2	G	M	thermostabilising	6FFH, 5CGC, 6FFI, 5CGD, 4OO9
GRM5	mGlu₅	5x42	742	TM5	T	A	thermostabilising	6FFH, 5CGC, 6FFI, 5CGD, 4OO9
GRM5	mGlu₅	5x53	753	TM5	S	A	thermostabilising	6FFH, 5CGC, 6FFI, 5CGD, 4OO9
GLP1R	GLP-1		207	ECL1	T	E	thermostabilising	5NX2
GLP1R	GLP-1		211	ECL1	Q	A	thermostabilising	5NX2
GLP1R	GLP-1		215	ECL1	D	R	thermostabilising	5NX2
GLP1R	GLP-1	3x31	232	TM3	L	F	thermostabilising	5NX2
GLP1R	GLP-1		260	ICL2	L	F	other-effect, thermostabilising	5NX2
GLP1R	GLP-1		295	ECL2	G	A	thermostabilising	5NX2
GLP1R	GLP-1	45x52	298	ECL2	T	A	thermostabilising	5NX2
GLP1R	GLP-1	5x63	329	TM5	C	A	thermostabilising	5NX2
GLP1R	GLP-1	6x42	358	TM6	P	A	thermostabilising	5NX2
GLP1R	GLP-1	6x45	361	TM6	G	A	thermostabilising	5NX2
GLP1R	GLP-1	6x47	363	TM6	H	V	thermostabilising	5NX2
GLP1R	GLP-1	7x56	405	TM7	V	A	thermostabilising	5NX2
FFAR1	FFA1	2x40	42	TM2	L	A	thermostabilising	5TZR, 4PHU, 5KW2, 5TZY
FFAR1	FFA1	3x49	103	TM3	G	A	thermostabilising	5TZR, 4PHU, 5KW2, 5TZY
FFAR1	FFA1	5x58	202	TM5	Y	F	thermostabilising	5TZR, 4PHU, 5KW2, 5TZY
G1SGD4	GLP-1		106	N-term	T	A	other-effect	5VAI
G1SGD4	GLP-1		112	N-term	H	P	other-effect	5VAI
G1SGD4	GLP-1	1x31	140	TM1	Q	R	other-effect	5VAI
GLP1R	GLP-1	2x56	193	TM2	S	C	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	2x59	196	TM2	I	F	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	3x24	225	TM3	S	A	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	3x32	233	TM3	M	C	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	4x48	271	TM4	S	A	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	5x51	317	TM5	I	C	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	5x52	318	TM5	G	I	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	6x30	346	TM6	K	A	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	6x31	347	TM6	C	F	thermostabilising	5VEW, 5VEX
GLP1R	GLP-1	6x45	361	TM6	G	C	thermostabilising	5VEW, 5VEX
OPSD	Rhodopsin	2x56	90	TM2	G	D	natural-mutation-snp-incl-disease-causing	4BEY, 4BEZ
OPRD	δ		37	N-term	P	S	other-effect	4N6H
NTR1	NTS₁	1x51	83	TM1	S	G	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	2x38	101	TM2	T	R	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	2x551	119	TM2	L	F	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	2x57	121	TM2	M	L	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	2x60	124	TM2	E	D	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	3x26	143	TM3	R	K	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	3x33	150	TM3	D	E	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	5x37	235	TM5	K	R	receptor-expression	4BWB
NTR1	NTS₁	5x42	240	TM5	V	L	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	5x61	260	TM5	I	A	receptor-expression	4BWB
NTR1	NTS₁	5x63	262	TM5	N	R	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	5x64	263	TM5	K	R	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	6x59	332	TM6	C	V	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	7x25	342	TM7	F	A	receptor-expression	4BV0, 4BWB
NTR1	NTS₁	7x37	354	TM7	T	S	receptor-expression	4BV0, 4BWB
PAR2	PAR2	1x46	89	TM1	G	A	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	2x37	108	TM2	H	A	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	3x34	157	TM3	G	A	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	3x43	166	TM3	M	L	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	3x51	174	TM3	Y	A	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	3x53	176	TM3	V	E	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2		222	ECL2	N	Q	glycosylation-site	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	5x64	268	TM5	M	A	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	6x38	289	TM6	I	A	thermostabilising	5NDZ, 5NJ6, 5NDD
PAR2	PAR2	6x42	293	TM6	L	A	thermostabilising	5NDZ, 5NJ6, 5NDD
APJ	apelin	3x40	117	TM3	V	A	thermostabilising	5VBL
APJ	apelin		177	ECL2	T	N	glycosylation-site	5VBL
APJ	apelin	6x48	261	TM6	W	K	thermostabilising	5VBL
APJ	apelin	8x59	325	H8	C	L	palmitoylation-site	5VBL
APJ	apelin	8x60	326	H8	C	M	palmitoylation-site	5VBL
AA1R	A₁		159	ECL2	N	A	glycosylation-site	5UEN, 5N2S
EDNRB	ET_B	1x55	124	TM1	R	Y	thermostabilising	5XPR, 5X93
EDNRB	ET_B	5x36	270	TM5	K	A	thermostabilising	5XPR, 5X93
EDNRB	ET_B	6x54	342	TM6	S	A	thermostabilising	5XPR, 5X93
EDNRB	ET_B	7x48	381	TM7	I	A	thermostabilising	5XPR, 5X93
EDNRB	ET_B	8x53	396	H8	C	A	palmitoylation-site	5XPR, 5X93
EDNRB	ET_B	8x57	400	H8	C	A	palmitoylation-site	5XPR, 5X93
EDNRB	ET_B		405	C-term	C	A	palmitoylation-site	5XPR, 5X93
PAR1	PAR1		250	ECL2	N	G	glycosylation-site	3VW7
PAR1	PAR1		259	ECL2	N	S	glycosylation-site	3VW7
GLR	glucagon	2x39	173	TM2	R	A	thermostabilising	5EE7, 5YQZ
OPSD	Rhodopsin		18	N-term	V	I	other-effect	2ZIY
EDNRB	ET_B	2x56	154	TM2	D	A	thermostabilising	5X93
CNR1	CB₁	5x37	273	TM5	E	K	thermostabilising, receptor-expression	5TGZ, 5XR8, 5XRA
CNR1	CB₁	5x47	283	TM5	T	V	receptor-expression	5TGZ, 5XR8, 5XRA
CNR1	CB₁	6x32	340	TM6	R	E	thermostabilising, receptor-expression	5TGZ, 5XR8, 5XRA
GLR	glucagon	1x48	154	TM1	G	A	thermostabilising	5EE7
GLR	glucagon	2x48	182	TM2	A	L	thermostabilising	5EE7
GLR	glucagon	2x56	190	TM2	S	A	thermostabilising	5EE7
GLR	glucagon	2x59	193	TM2	V	F	thermostabilising	5EE7
GLR	glucagon		207	ECL1	G	E	thermostabilising	5EE7
GLR	glucagon	3x24	223	TM3	G	A	thermostabilising	5EE7
GLR	glucagon	4x54	276	TM4	M	A	thermostabilising	5EE7
GLR	glucagon	6x30	344	TM6	K	A	thermostabilising	5EE7
GLR	glucagon	6x48	362	TM6	E	F	thermostabilising	5EE7
GLR	glucagon	7x39	387	TM7	F	A	thermostabilising	5EE7
FFAR1	FFA1	3x34	88	TM3	F	A	thermostabilising	5TZR, 4PHU, 5KW2
AA1R	A₁	2x52	57	TM2	A	L	thermostabilising	5N2S
AA1R	A₁	3x36	91	TM3	T	A	thermostabilising	5N2S
AA1R	A₁	5x63	205	TM5	Y	A	thermostabilising	5N2S
AA1R	A₁	6x37	236	TM6	L	A	thermostabilising	5N2S
AA1R	A₁	6x41	240	TM6	L	A	thermostabilising	5N2S
AA1R	A₁	7x41	277	TM7	T	A	thermostabilising	5N2S
AA1R	A₁	8x64	309	H8	C	S	palmitoylation-site	5N2S
CCR9	CCR9		34	N-term	T	E	glycosylation-site	5LWE
CCR9	CCR9	12x48	77	ICL1	T	A	thermostabilising	5LWE
CCR9	CCR9	12x50	79	ICL1	V	A	thermostabilising	5LWE
CCR9	CCR9	2x38	82	TM2	M	A	thermostabilising	5LWE
CCR9	CCR9	3x47	141	TM3	S	C	thermostabilising	5LWE
CCR9	CCR9	5x41	216	TM5	T	A	thermostabilising	5LWE
CCR9	CCR9	6x36	255	TM6	V	A	thermostabilising	5LWE
CCR9	CCR9	7x29	294	TM7	N	A	thermostabilising	5LWE
CCR9	CCR9	7x39	304	TM7	T	A	thermostabilising	5LWE
CCR9	CCR9	8x63	337	H8	C	A	palmitoylation-site	5LWE
ADRB1	β₁	3x41	130	TM3	E	W	thermostabilising	5A8E
DRD3	D₃	3x41	119	TM3	L	W	thermostabilising	3PBL
NTR1	NTS₁	2x61	125	TM2	L	V	receptor-expression	4BV0
NTR1	NTS₁	3x55	172	TM3	C	R	receptor-expression	4BV0
NTR1	NTS₁	34x53	177	ICL2	A	H	receptor-expression	4BV0
NTR1	NTS₁	4x65	208	TM4	M	V	receptor-expression	4BV0
NTR1	NTS₁	6x40	313	TM6	V	M	receptor-expression	4BV0

CCR5

4x61

163

TM4

G

N

thermostabilising

6AKX, 5UIW, 7F1R, 6AKY, 7F1Q, 7F1T, 4MBS, 7F1S

DRD2

D₂

3x40

122

TM3

I

A

thermostabilising

6CM4

DRD2

D₂

6x37

375

TM6

L

A

thermostabilising

6CM4

DRD2

D₂

6x41

379

TM6

L

A

thermostabilising

6CM4

Q9WTK1

BLT₁

2x67

83

TM2

H

G

thermostabilising

5X33

Q9WTK1

BLT₁

3x21

88

TM3

K

G

thermostabilising

5X33

Q9WTK1

BLT₁

5x67

212

TM5

V

A

thermostabilising

5X33

Q9WTK1

BLT₁

309

C-term

S

A

thermostabilising

5X33

NTR1

NTS₁

1x54

86

TM1

A

L

thermostabilising

4BV0, 5T04, 7L0R, 3ZEV, 7L0Q, 4BUO, 4BWB, 7L0S, 4XES, 4GRV, 7L0P, 4XEE

NTR1

NTS₁

2x40

103

TM2

H

D

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

2x42

105

TM2

H

Y

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

3x44

161

TM3

A

V

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

3x50

167

TM3

R

L

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

213

ECL2

R

L

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

5x36

234

TM5

V

L

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

5x54

253

TM5

I

A

thermostabilising

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

6x32

305

TM6

H

R

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

7x41

358

TM7

F

V

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

NTR1

NTS₁

7x46

362

TM7

S

A

receptor-expression

3ZEV, 4BV0, 4BUO, 4BWB

5HT1B

5-HT_1B

3x41

138

TM3

L

W

thermostabilising

7C61, 4IAQ, 6G79, 5V54, 4IAR

S1PR1

S1P₁

6x30

251

TM6

S

N

other-effect

3V2W, 3V2Y

S1PR1

S1P₁

6x31

252

TM6

L

V

other-effect

3V2W, 3V2Y

C5AR1

C5a₁

2x53

85

TM2

S

A

palmitoylation-site

5O9H

C5AR1

C5a₁

2x59

91

TM2

I

A

palmitoylation-site

5O9H

C5AR1

C5a₁

34x51

142

ICL2

I

A

palmitoylation-site

5O9H

C5AR1

C5a₁

34x55

146

ICL2

N

R

palmitoylation-site

5O9H

C5AR1

C5a₁

4x45

156

TM4

A

L

palmitoylation-site

5O9H

C5AR1

C5a₁

4x62

172

TM4

F

A

palmitoylation-site

5O9H

C5AR1

C5a₁

5x68

232

TM5

R

A

palmitoylation-site

5O9H

C5AR1

C5a₁

234

ICL3

A

E

palmitoylation-site

5O9H

C5AR1

C5a₁

311

C-term

L

E

palmitoylation-site

5O9H

C5AR1

C5a₁

317

C-term

S

E

palmitoylation-site

5O9H

C5AR1

C5a₁

321

C-term

N

E

palmitoylation-site

5O9H

ADRB1

β₁

1x59

68

TM1

R

S

thermostabilising

6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O

ADRB1

β₁

2x53

90

TM2

M

V

thermostabilising

6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO

ADRB1

β₁

3x27

116

TM3

C

L

receptor-expression

6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO

ADRB1

β₁

5x58

227

TM5

Y

A

thermostabilising

2Y00, 3ZPQ, 2Y04, 2Y02, 4AMI, 2YCX, 2YCW, 5F8U, 2Y03, 2YCY, 2YCZ, 2VT4, 5A8E, 4BVN, 4GPO, 3ZPR, 4AMJ, 2Y01

ADRB1

β₁

6x27

282

TM6

A

L

thermostabilising

2Y00, 3ZPQ, 2Y04, 2Y02, 4AMI, 2YCX, 2YCW, 5F8U, 2Y03, 2YCY, 2YCZ, 2VT4, 5A8E, 4BVN, 4GPO, 3ZPR, 4AMJ, 2Y01

ADRB1

β₁

7x36

327

TM7

F

A

thermostabilising

6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO

ADRB1

β₁

7x48

338

TM7

F

M

thermostabilising

6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O, 6TKO

ADRB1

β₁

8x59

358

H8

C

A

palmitoylation-site

6H7L, 6H7M, 2Y02, 4AMI, 2YCX, 2YCZ, 2YCY, 2VT4, 4GPO, 5F8U, 2Y04, 6H7N, 2YCW, 6H7J, 4AMJ, 2Y01, 3ZPQ, 2Y03, 6IBL, 5A8E, 4BVN, 3ZPR, 2Y00, 6H7O

OPSD

Rhodopsin

2

N-term

N

C

receptor-disulfide-bridge, other-effect, thermostabilising

5W0P, 5DGY, 4ZWJ

OPSD

Rhodopsin

3x28

113

TM3

E

Q

thermostabilising

5W0P, 6CMO, 5DGY, 4ZWJ

OPSD

Rhodopsin

6x40

257

TM6

M

Y

thermostabilising

5W0P, 6CMO, 5DGY, 4ZWJ

OPSD

Rhodopsin

282

ECL3

N

C

receptor-disulfide-bridge, thermostabilising

5W0P, 6CMO, 5DGY, 4ZWJ

PTAFR

PAF

3x51

116

TM3

F

Y

receptor-expression

5ZKQ, 5ZKP

PTAFR

PAF

169

ECL2

N

D

glycosylation-site

5ZKQ, 5ZKP

PTAFR

PAF

6x34

230

TM6

A

D

thermostabilising

5ZKQ, 5ZKP

PTAFR

PAF

6x38

234

TM6

V

A

receptor-expression

5ZKQ, 5ZKP

PTAFR

PAF

7x49

289

TM7

D

N

receptor-expression

5ZKQ, 5ZKP

CRFR1

CRF₁

1x36

120

TM1

V

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

1x60

144

TM1

L

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

2x44

156

TM2

W

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

2x48

160

TM2

S

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

4x43

228

TM4

K

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

45x52

260

ECL2

F

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

5x48

277

TM5

I

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

6x30

309

TM6

Y

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

6x51

330

TM6

F

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

7x38

349

TM7

S

A

thermostabilising

4Z9G, 4K5Y

CRFR1

CRF₁

7x53

363

TM7

Y

A

thermostabilising

4Z9G, 4K5Y

5HT2B

5-HT_2B

3x41

144

TM3

M

W

thermostabilising

5TVN, 5TUD, 6DRY, 4IB4, 6DRZ, 6DS0, 6DRX, 4NC3

AA2AR

A_2A

2x52

54

TM2

A

L

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 4UHR, 3RFM, 4UG2, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 2YDV, 3UZC, 5MZP, 3UZA, 2YDO, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

AA2AR

A_2A

3x36

88

TM3

T

A

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

AA2AR

A_2A

3x55

107

TM3

R

A

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

AA2AR

A_2A

4x43

122

TM4

K

A

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

AA2AR

A_2A

154

ECL2

N

A

glycosylation-site

5IU4, 5N2R, 5OLG, 5OM1, 5G53, 5OLZ, 4UHR, 4UG2, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 2YDV, 5MZP, 2YDO, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 6GDG

AA2AR

A_2A

5x63

202

TM5

L

A

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

AA2AR

A_2A

6x37

235

TM6

L

A

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

AA2AR

A_2A

6x41

239

TM6

V

A

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

AA2AR

A_2A

7x41

277

TM7

S

A

thermostabilising

5IU4, 5N2R, 5OLG, 5OM1, 3REY, 5OLZ, 3RFM, 5IUA, 5OM4, 5MZJ, 5NM2, 5IUB, 3UZC, 5MZP, 3UZA, 5NM4, 5IU7, 5IU8, 5NLX, 5OLV, 5OLO, 5OLH, 3PWH

ADRB2

β₂

16

N-term

G

R

other-effect

2RH1, 3D4S, 5D6L, 3NY9, 3KJ6, 5X7D, 5D5A, 2R4R, 5D5B, 3NY8, 3P0G, 3NYA

ADRB2

β₂

1x26

27

TM1

E

Q

other-effect

2RH1, 3D4S, 3PDS, 5D6L, 3NY9, 3KJ6, 5X7D, 5D5A, 2R4S, 2R4R, 5D5B, 3NY8, 3P0G, 3NYA

ADRB2

β₂

187

ECL2

N

E

glycosylation-site

6PS3, 6NI3, 6MXT, 4GBR, 3KJ6, 6PS1, 6E67, 4LDO, 7DHI, 6PS4, 4LDL, 3P0G, 6OBA, 3SN6, 3NY9, 4LDE, 6PRZ, 3NY8, 6PS5, 7DHR, 5D5B, 3NYA, 2RH1, 3D4S, 3PDS, 5D6L, 5X7D, 5D5A, 5JQH, 4QKX, 6PS6, 6PS2, 6N48, 6PS0

NPY1R

Y₁

3x41

129

TM3

F

W

thermostabilising

5ZBQ, 5ZBH

CNR1

CB₁

3x46

210

TM3

T

A

thermostabilising

5U09, 5XR8, 5XRA, 5TGZ

CCR5

1x60

58

TM1

C

Y

thermostabilising

6AKX, 5UIW, 6AKY, 7F1T, 4MBS

CCR5

6x33

233

TM6

A

D

thermostabilising, receptor-salt-bridge

6AKX, 5UIW, 6AKY, 7F1T, 4MBS

CCR5

8x49

303

H8

K

E

thermostabilising

6AKX, 5UIW, 6AKY, 7F1T, 4MBS

ADRB2

β₂

3x41

122

TM3

E

W

thermostabilising, receptor-expression

3NY9, 3NY8, 3D4S, 3NYA

OPRK

κ

3x29

135

TM3

I

L

receptor-expression

6B73, 6VI4, 4DJH

ACM1

M₁

2

N-term

N

Q

glycosylation-site

5CXV, 6OIJ, 6WJC

ACM1

M₁

12

N-term

N

Q

glycosylation-site

5CXV, 6OIJ, 6WJC

ACM1

M₁

3x37

110

TM3

N

Q

glycosylation-site

5CXV, 6OIJ, 6WJC

AA2AR

A_2A

154

ECL2

N

Q

glycosylation-site

3VG9, 3VGA

OX1R

OX₁

6x56

319

TM6

V

I

other-effect

6V9S, 4ZJC, 4ZJ8

OPSD

Rhodopsin

2

N-term

N

C

receptor-disulfide-bridge, thermostabilising

6FKC, 6FKD, 2X72, 6FKA, 6FK6, 4BEY, 5DYS, 3C9M, 6FK7, 4BEZ, 6FK8, 6FKB, 5EN0, 4A4M, 2J4Y, 6FK9

OPSD

Rhodopsin

282

ECL3

D

C

receptor-disulfide-bridge, thermostabilising

6FKC, 6FKD, 2X72, 6FKA, 6FK6, 4BEY, 5DYS, 3C9M, 6FK7, 4BEZ, 6FK8, 6FKB, 5EN0, 4A4M, 2J4Y, 6FK9

AA2AR

A_2A

2x46

48

TM2

L

A

thermostabilising

4UHR, 4UG2, 2YDO, 2YDV

AA2AR

A_2A

2x62

65

TM2

T

A

thermostabilising

4UHR, 4UG2, 2YDO, 2YDV

AA2AR

A_2A

3x37

89

TM3

Q

A

thermostabilising

4UHR, 4UG2, 2YDO, 2YDV

OX2R

OX₂

6x39

308

TM6

I

V

other-effect

5WQC, 4S0V, 5WS3

CXCR4

3x41

125

TM3

L

W

thermostabilising

3ODU, 4RWS, 3OE6, 3OE8, 3OE9, 3OE0

CXCR4

6x36

240

TM6

T

P

thermostabilising

4RWS, 3OE9, 3OE0

ACM2

M₂

3

N-term

N

D

glycosylation-site

6OIK, 4MQT, 4MQS, 3UON

ACM2

M₂

6

N-term

N

D

glycosylation-site

6OIK, 4MQT, 4MQS, 3UON

ACM2

M₂

9

N-term

N

D

glycosylation-site

6OIK, 4MQT, 4MQS, 3UON

ACM2

M₂

2

N-term

N

D

glycosylation-site

4MQT, 4MQS, 3UON

ACM2

M₂

373

ICL3

A

T

other-effect

4MQT, 4MQS

ACM2

M₂

374

ICL3

K

R

other-effect

4MQT, 4MQS

ADRB2

β₂

2x66

96

TM2

M

T

receptor-expression

3SN6, 4LDL, 5JQH, 4LDO, 4QKX, 4LDE, 4GBR

ADRB2

β₂

23x49

98

ECL1

M

T

receptor-expression

3SN6, 4LDL, 5JQH, 4LDO, 4QKX, 4LDE, 4GBR

ADRB2

β₂

6x27

265

TM6

C

A

other-effect

4LDL, 5JQH, 4LDO, 4QKX, 4LDE

ADRB2

β₂

2x63

93

TM2

H

C

receptor-ligand-bond, thermostabilising

4QKX, 3PDS

OPSD

Rhodopsin

336

C-term

T

X

phosphorylation-site

5W0P

OPSD

Rhodopsin

338

C-term

S

X

phosphorylation-site

5W0P

OPSD

Rhodopsin

3x28

113

TM3

E

Q

thermostabilising

2X72

P2RY1

P2Y₁

7x49

320

TM7

D

N

thermostabilising, receptor-expression

4XNV, 4XNW

C5AR1

C5a₁

34x53

144

ICL2

C

X

6C1R, 6C1Q

NTR1

NTS₁

3x49

166

TM3

E

A

thermostabilising

4XES, 4GRV

NTR1

NTS₁

215

ECL2

G

A

thermostabilising

4XEE, 4XES, 5T04, 4GRV

NTR1

NTS₁

6x37

310

TM6

L

A

thermostabilising

4GRV

NTR1

NTS₁

7x41

358

TM7

F

A

receptor-expression

5T04, 4GRV

NTR1

NTS₁

7x43

360

TM7

V

A

thermostabilising

4XEE, 4XES, 5T04, 4GRV

LPAR1

LPA₁

5x37

204

TM5

D

C

receptor-disulfide-bridge, thermostabilising

4Z36

LPAR1

LPA₁

6x59

282

TM6

V

C

receptor-disulfide-bridge, thermostabilising

4Z36

5HT2C

5-HT_2C

7x45

360

TM7

C

N

thermostabilising, receptor-expression

6BQH, 6BQG

P2Y12

P2Y₁₂

7x49

294

TM7

D

N

thermostabilising, receptor-expression

4PY0, 4PXZ, 4NTJ

SMO

3x40

329

TM3

V

F

thermostabilising, receptor-expression

5L7I, 5L7D

SMO

194

N-term

E

M

receptor-expression

5V56

ADRB1

β₁

3x40

129

TM3

I

V

thermostabilising

4BVN, 5A8E

ADRB1

β₁

7x31

322

TM7

D

K

thermostabilising

4BVN

ADRB1

β₁

7x53

343

TM7

Y

L

thermostabilising

4BVN, 5A8E

OPSD

Rhodopsin

6x40

257

TM6

M

Y

thermostabilising

4A4M

AA2AR

A_2A

2x50

52

TM2

D

N

thermostabilising

5WF5

AA2AR

A_2A

3x39

91

TM3

S

A

thermostabilising

5WF6

OPSD

Rhodopsin

2x60

94

TM2

T

I

thermostabilising

5EN0, 5DYS

CXCR4

45x51

187

ECL2

D

C

receptor-ligand-bond, thermostabilising

4RWS

GRM5

mGlu₅

1x35

579

TM1

E

A

thermostabilising

6FFH, 5CGC, 6FFI, 5CGD, 4OO9

GRM5

mGlu₅

3x48

667

TM3

N

Y

thermostabilising

6FFH, 5CGC, 6FFI, 5CGD, 4OO9

GRM5

mGlu₅

3x50

669

TM3

I

A

thermostabilising

6FFH, 5CGC, 6FFI, 5CGD, 4OO9

GRM5

mGlu₅

675

ICL2

G

M

thermostabilising

6FFH, 5CGC, 6FFI, 5CGD, 4OO9

GRM5

mGlu₅

5x42

742

TM5

T

A

thermostabilising

6FFH, 5CGC, 6FFI, 5CGD, 4OO9

GRM5

mGlu₅

5x53

753

TM5

S

A

thermostabilising

6FFH, 5CGC, 6FFI, 5CGD, 4OO9

GLP1R

GLP-1

207

ECL1

T

E

thermostabilising

5NX2

GLP1R

GLP-1

211

ECL1

Q

A

thermostabilising

5NX2

GLP1R

GLP-1

215

ECL1

D

R

thermostabilising

5NX2

GLP1R

GLP-1

3x31

232

TM3

L

F

thermostabilising

5NX2

GLP1R

GLP-1

260

ICL2

L

F

other-effect, thermostabilising

5NX2

GLP1R

GLP-1

295

ECL2

G

A

thermostabilising

5NX2

GLP1R

GLP-1

45x52

298

ECL2

T

A

thermostabilising

5NX2

GLP1R

GLP-1

5x63

329

TM5

C

A

thermostabilising

5NX2

GLP1R

GLP-1

6x42

358

TM6

P

A

thermostabilising

5NX2

GLP1R

GLP-1

6x45

361

TM6

G

A

thermostabilising

5NX2

GLP1R

GLP-1

6x47

363

TM6

H

V

thermostabilising

5NX2

GLP1R

GLP-1

7x56

405

TM7

V

A

thermostabilising

5NX2

FFAR1

FFA1

2x40

42

TM2

L

A

thermostabilising

5TZR, 4PHU, 5KW2, 5TZY

FFAR1

FFA1

3x49

103

TM3

G

A

thermostabilising

5TZR, 4PHU, 5KW2, 5TZY

FFAR1

FFA1

5x58

202

TM5

Y

F

thermostabilising

5TZR, 4PHU, 5KW2, 5TZY

G1SGD4

GLP-1

106

N-term

T

A

other-effect

5VAI

G1SGD4

GLP-1

112

N-term

H

P

other-effect

5VAI

G1SGD4

GLP-1

1x31

140

TM1

Q

R

other-effect

5VAI

GLP1R

GLP-1

2x56

193

TM2

S

C

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

2x59

196

TM2

I

F

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

3x24

225

TM3

S

A

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

3x32

233

TM3

M

C

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

4x48

271

TM4

S

A

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

5x51

317

TM5

I

C

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

5x52

318

TM5

G

I

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

6x30

346

TM6

K

A

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

6x31

347

TM6

C

F

thermostabilising

5VEW, 5VEX

GLP1R

GLP-1

6x45

361

TM6

G

C

thermostabilising

5VEW, 5VEX

OPSD

Rhodopsin

2x56

90

TM2

G

D

natural-mutation-snp-incl-disease-causing

4BEY, 4BEZ

OPRD

δ

37

N-term

P

S

other-effect

4N6H

NTR1

NTS₁

1x51

83

TM1

S

G

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

2x38

101

TM2

T

R

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

2x551

119

TM2

L

F

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

2x57

121

TM2

M

L

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

2x60

124

TM2

E

D

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

3x26

143

TM3

R

K

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

3x33

150

TM3

D

E

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

5x37

235

TM5

K

R

receptor-expression

4BWB

NTR1

NTS₁

5x42

240

TM5

V

L

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

5x61

260

TM5

I

A

receptor-expression

4BWB

NTR1

NTS₁

5x63

262

TM5

N

R

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

5x64

263

TM5

K

R

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

6x59

332

TM6

C

V

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

7x25

342

TM7

F

A

receptor-expression

4BV0, 4BWB

NTR1

NTS₁

7x37

354

TM7

T

S

receptor-expression

4BV0, 4BWB

PAR2

1x46

89

TM1

G

A

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

2x37

108

TM2

H

A

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

3x34

157

TM3

G

A

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

3x43

166

TM3

M

L

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

3x51

174

TM3

Y

A

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

3x53

176

TM3

V

E

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

222

ECL2

N

Q

glycosylation-site

5NDZ, 5NJ6, 5NDD

PAR2

5x64

268

TM5

M

A

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

6x38

289

TM6

I

A

thermostabilising

5NDZ, 5NJ6, 5NDD

PAR2

6x42

293

TM6

L

A

thermostabilising

5NDZ, 5NJ6, 5NDD

APJ

apelin

3x40

117

TM3

V

A

thermostabilising

5VBL

APJ

apelin

177

ECL2

T

N

glycosylation-site

5VBL

APJ

apelin

6x48

261

TM6

W

K

thermostabilising

5VBL

APJ

apelin

8x59

325

H8

C

L

palmitoylation-site

5VBL

APJ

apelin

8x60

326

H8

C

M

palmitoylation-site

5VBL

AA1R

A₁

159

ECL2

N

A

glycosylation-site

5UEN, 5N2S

EDNRB

ET_B

1x55

124

TM1

R

Y

thermostabilising

5XPR, 5X93

EDNRB

ET_B

5x36

270

TM5

K

A

thermostabilising

5XPR, 5X93

EDNRB

ET_B

6x54

342

TM6

S

A

thermostabilising

5XPR, 5X93

EDNRB

ET_B

7x48

381

TM7

I

A

thermostabilising

5XPR, 5X93

EDNRB

ET_B

8x53

396

H8

C

A

palmitoylation-site

5XPR, 5X93

EDNRB

ET_B

8x57

400

H8

C

A

palmitoylation-site

5XPR, 5X93

EDNRB

ET_B

405

C-term

C

A

palmitoylation-site

5XPR, 5X93

PAR1

250

ECL2

N

G

glycosylation-site

3VW7

PAR1

259

ECL2

N

S

glycosylation-site

3VW7

GLR

glucagon

2x39

173

TM2

R

A

thermostabilising

5EE7, 5YQZ

OPSD

Rhodopsin

18

N-term

V

I

other-effect

2ZIY

EDNRB

ET_B

2x56

154

TM2

D

A

thermostabilising

5X93

CNR1

CB₁

5x37

273

TM5

E

K

thermostabilising, receptor-expression

5TGZ, 5XR8, 5XRA

CNR1

CB₁

5x47

283

TM5

T

V

receptor-expression

5TGZ, 5XR8, 5XRA

CNR1

CB₁

6x32

340

TM6

R

E

thermostabilising, receptor-expression

5TGZ, 5XR8, 5XRA

GLR

glucagon

1x48

154

TM1

G

A

thermostabilising

5EE7

GLR

glucagon

2x48

182

TM2

A

L

thermostabilising

5EE7

GLR

glucagon

2x56

190

TM2

S

A

thermostabilising

5EE7

GLR

glucagon

2x59

193

TM2

V

F

thermostabilising

5EE7

GLR

glucagon

207

ECL1

G

E

thermostabilising

5EE7

GLR

glucagon

3x24

223

TM3

G

A

thermostabilising

5EE7

GLR

glucagon

4x54

276

TM4

M

A

thermostabilising

5EE7

GLR

glucagon

6x30

344

TM6

K

A

thermostabilising

5EE7

GLR

glucagon

6x48

362

TM6

E

F

thermostabilising

5EE7

GLR

glucagon

7x39

387

TM7

F

A

thermostabilising

5EE7

FFAR1

FFA1

3x34

88

TM3

F

A

thermostabilising

5TZR, 4PHU, 5KW2

AA1R

A₁

2x52

57

TM2

A

L

thermostabilising

5N2S

AA1R

A₁

3x36

91

TM3

T

A

thermostabilising

5N2S

AA1R

A₁

5x63

205

TM5

Y

A

thermostabilising

5N2S

AA1R

A₁

6x37

236

TM6

L

A

thermostabilising

5N2S

AA1R

A₁

6x41

240

TM6

L

A

thermostabilising

5N2S

AA1R

A₁

7x41

277

TM7

T

A

thermostabilising

5N2S

AA1R

A₁

8x64

309

H8

C

S

palmitoylation-site

5N2S

CCR9

34

N-term

T

E

glycosylation-site

5LWE

CCR9

12x48

77

ICL1

T

A

thermostabilising

5LWE

CCR9

12x50

79

ICL1

V

A

thermostabilising

5LWE

CCR9

2x38

82

TM2

M

A

thermostabilising

5LWE

CCR9

3x47

141

TM3

S

C

thermostabilising

5LWE

CCR9

5x41

216

TM5

T

A

thermostabilising

5LWE

CCR9

6x36

255

TM6

V

A

thermostabilising

5LWE

CCR9

7x29

294

TM7

N

A

thermostabilising

5LWE

CCR9

7x39

304

TM7

T

A

thermostabilising

5LWE

CCR9

8x63

337

H8

C

A

palmitoylation-site

5LWE

ADRB1

β₁

3x41

130

TM3

E

W

thermostabilising

5A8E

DRD3

D₃

3x41

119

TM3

L

W

thermostabilising

3PBL

NTR1

NTS₁

2x61

125

TM2

L

V

receptor-expression

4BV0

NTR1

NTS₁

3x55

172

TM3

C

R

receptor-expression

4BV0

NTR1

NTS₁

34x53

177

ICL2

A

H

receptor-expression

4BV0

NTR1

NTS₁

4x65

208

TM4

M

V

receptor-expression

4BV0

NTR1

NTS₁

6x40

313

TM6

V

M

receptor-expression

4BV0

Package	Name	Version
Django		2.2.1
Python		3.6.7
debug_toolbar	Debug Toolbar	1.11
polymorphic	Polymorphic	2.0.3
rest_framework	Django REST framework	3.9.3
rest_framework_swagger	Rest_Framework_Swagger	2.2.0

Resource	Value
User CPU time	40.351 msec
System CPU time	0.129 msec
Total CPU time	40.480 msec
Elapsed time	41.264 msec
Context switches	3 voluntary, 0 involuntary

Setting	Value
ABSOLUTE_URL_OVERRIDES	`{}`
ADMINS	`[]`
ALLOWED_HOSTS	`['*']`
APPEND_SLASH	`True`
AUTHENTICATION_BACKENDS	`['django.contrib.auth.backends.ModelBackend']`
AUTH_PASSWORD_VALIDATORS	`'********************'`
AUTH_USER_MODEL	`'auth.User'`
BASE_DIR	`'/home/protwis/gpcrdb_test'`
BUILD_CACHE_DIR	`'/home/protwis/gpcrdb_data/cache'`
CACHES	`{'alignments': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test_alignment', 'OPTIONS': {'MAX_ENTRIES': 1000}}, 'default': {'BACKEND': 'django.core.cache.backends.filebased.FileBasedCache', 'LOCATION': '/home/protwis/caches/test/', 'OPTIONS': {'MAX_ENTRIES': 10000000}}}`
CACHE_MIDDLEWARE_ALIAS	`'default'`
CACHE_MIDDLEWARE_KEY_PREFIX	`'********************'`
CACHE_MIDDLEWARE_SECONDS	`600`
CSRF_COOKIE_AGE	`31449600`
CSRF_COOKIE_DOMAIN	`None`
CSRF_COOKIE_HTTPONLY	`False`
CSRF_COOKIE_NAME	`'csrftoken'`
CSRF_COOKIE_PATH	`'/'`
CSRF_COOKIE_SAMESITE	`'Lax'`
CSRF_COOKIE_SECURE	`False`
CSRF_FAILURE_VIEW	`'django.views.csrf.csrf_failure'`
CSRF_HEADER_NAME	`'HTTP_X_CSRFTOKEN'`
CSRF_TRUSTED_ORIGINS	`[]`
CSRF_USE_SESSIONS	`False`
DATABASES	`{'default': {'ATOMIC_REQUESTS': False, 'AUTOCOMMIT': True, 'CONN_MAX_AGE': 0, 'ENGINE': 'django.db.backends.postgresql_psycopg2', 'HOST': 'localhost', 'NAME': 'protwis_202107', 'OPTIONS': {}, 'PASSWORD': '********************', 'PORT': '', 'TEST': {'CHARSET': None, 'COLLATION': None, 'MIRROR': None, 'NAME': None}, 'TIME_ZONE': None, 'USER': 'protwis'}}`
DATABASE_ROUTERS	`[]`
DATA_DIR	`'/home/protwis/gpcrdb_data'`
DATA_UPLOAD_MAX_MEMORY_SIZE	`2621440`
DATA_UPLOAD_MAX_NUMBER_FIELDS	`1000`
DATETIME_FORMAT	`'N j, Y, P'`
DATETIME_INPUT_FORMATS	`['%Y-%m-%d %H:%M:%S', '%Y-%m-%d %H:%M:%S.%f', '%Y-%m-%d %H:%M', '%Y-%m-%d', '%m/%d/%Y %H:%M:%S', '%m/%d/%Y %H:%M:%S.%f', '%m/%d/%Y %H:%M', '%m/%d/%Y', '%m/%d/%y %H:%M:%S', '%m/%d/%y %H:%M:%S.%f', '%m/%d/%y %H:%M', '%m/%d/%y']`
DATE_FORMAT	`'N j, Y'`
DATE_INPUT_FORMATS	`['%Y-%m-%d', '%m/%d/%Y', '%m/%d/%y', '%b %d %Y', '%b %d, %Y', '%d %b %Y', '%d %b, %Y', '%B %d %Y', '%B %d, %Y', '%d %B %Y', '%d %B, %Y']`
DEBUG	`True`
DEBUG_PROPAGATE_EXCEPTIONS	`False`
DEBUG_TOOLBAR_PATCH_SETTINGS	`False`
DECIMAL_SEPARATOR	`'.'`
DEFAULT_CHARSET	`'utf-8'`
DEFAULT_CONTENT_TYPE	`'text/html'`
DEFAULT_EXCEPTION_REPORTER_FILTER	`'django.views.debug.SafeExceptionReporterFilter'`
DEFAULT_FILE_STORAGE	`'django.core.files.storage.FileSystemStorage'`
DEFAULT_FROM_EMAIL	`'webmaster@localhost'`
DEFAULT_INDEX_TABLESPACE	`''`
DEFAULT_NUMBERING_SCHEME	`'gpcrdb'`
DEFAULT_PROTEIN_STATE	`'inactive'`
DEFAULT_SITE	`'gpcr'`
DEFAULT_TABLESPACE	`''`
DISALLOWED_USER_AGENTS	`[]`
DOCUMENTATION_URL	`'https://docs.gpcrdb.org/'`
EMAIL_BACKEND	`'django.core.mail.backends.smtp.EmailBackend'`
EMAIL_HOST	`'localhost'`
EMAIL_HOST_PASSWORD	`'********************'`
EMAIL_HOST_USER	`''`
EMAIL_PORT	`25`
EMAIL_SSL_CERTFILE	`None`
EMAIL_SSL_KEYFILE	`'********************'`
EMAIL_SUBJECT_PREFIX	`'[Django] '`
EMAIL_TIMEOUT	`None`
EMAIL_USE_LOCALTIME	`False`
EMAIL_USE_SSL	`False`
EMAIL_USE_TLS	`False`
FILE_CHARSET	`'utf-8'`
FILE_UPLOAD_DIRECTORY_PERMISSIONS	`None`
FILE_UPLOAD_HANDLERS	`['django.core.files.uploadhandler.MemoryFileUploadHandler', 'django.core.files.uploadhandler.TemporaryFileUploadHandler']`
FILE_UPLOAD_MAX_MEMORY_SIZE	`2621440`
FILE_UPLOAD_PERMISSIONS	`None`
FILE_UPLOAD_TEMP_DIR	`None`
FIRST_DAY_OF_WEEK	`0`
FIXTURE_DIRS	`[]`
FORCE_SCRIPT_NAME	`None`
FORMAT_MODULE_PATH	`None`
FORM_RENDERER	`'django.forms.renderers.DjangoTemplates'`
GOOGLE_ANALYTICS_API	`'********************'`
GOOGLE_ANALYTICS_KEY	`'********************'`
IGNORABLE_404_URLS	`[]`
INSTALLED_APPS	('django.contrib.admin', 'django.contrib.auth', 'django.contrib.contenttypes', 'django.contrib.sessions', 'django.contrib.messages', 'django.contrib.staticfiles', 'django.contrib.humanize', 'debug_toolbar', 'rest_framework', 'rest_framework_swagger', 'polymorphic', 'common', 'api', 'news', 'pages', 'home', 'protein', 'family', 'residue', 'alignment', 'similaritysearch', 'similaritymatrix', 'structure', 'ligand', 'interaction', 'mutation', 'phylogenetic_trees', 'sitesearch', 'build_gpcr', 'construct', 'tools', 'drugs', 'signprot', 'signprot2', 'mutational_landscape', 'contactnetwork', 'seqsign', 'angles', 'hotspots')
INTERNAL_IPS	`'10.0.2.2'`
LANGUAGES	[('af', 'Afrikaans'), ('ar', 'Arabic'), ('ast', 'Asturian'), ('az', 'Azerbaijani'), ('bg', 'Bulgarian'), ('be', 'Belarusian'), ('bn', 'Bengali'), ('br', 'Breton'), ('bs', 'Bosnian'), ('ca', 'Catalan'), ('cs', 'Czech'), ('cy', 'Welsh'), ('da', 'Danish'), ('de', 'German'), ('dsb', 'Lower Sorbian'), ('el', 'Greek'), ('en', 'English'), ('en-au', 'Australian English'), ('en-gb', 'British English'), ('eo', 'Esperanto'), ('es', 'Spanish'), ('es-ar', 'Argentinian Spanish'), ('es-co', 'Colombian Spanish'), ('es-mx', 'Mexican Spanish'), ('es-ni', 'Nicaraguan Spanish'), ('es-ve', 'Venezuelan Spanish'), ('et', 'Estonian'), ('eu', 'Basque'), ('fa', 'Persian'), ('fi', 'Finnish'), ('fr', 'French'), ('fy', 'Frisian'), ('ga', 'Irish'), ('gd', 'Scottish Gaelic'), ('gl', 'Galician'), ('he', 'Hebrew'), ('hi', 'Hindi'), ('hr', 'Croatian'), ('hsb', 'Upper Sorbian'), ('hu', 'Hungarian'), ('hy', 'Armenian'), ('ia', 'Interlingua'), ('id', 'Indonesian'), ('io', 'Ido'), ('is', 'Icelandic'), ('it', 'Italian'), ('ja', 'Japanese'), ('ka', 'Georgian'), ('kab', 'Kabyle'), ('kk', 'Kazakh'), ('km', 'Khmer'), ('kn', 'Kannada'), ('ko', 'Korean'), ('lb', 'Luxembourgish'), ('lt', 'Lithuanian'), ('lv', 'Latvian'), ('mk', 'Macedonian'), ('ml', 'Malayalam'), ('mn', 'Mongolian'), ('mr', 'Marathi'), ('my', 'Burmese'), ('nb', 'Norwegian Bokmål'), ('ne', 'Nepali'), ('nl', 'Dutch'), ('nn', 'Norwegian Nynorsk'), ('os', 'Ossetic'), ('pa', 'Punjabi'), ('pl', 'Polish'), ('pt', 'Portuguese'), ('pt-br', 'Brazilian Portuguese'), ('ro', 'Romanian'), ('ru', 'Russian'), ('sk', 'Slovak'), ('sl', 'Slovenian'), ('sq', 'Albanian'), ('sr', 'Serbian'), ('sr-latn', 'Serbian Latin'), ('sv', 'Swedish'), ('sw', 'Swahili'), ('ta', 'Tamil'), ('te', 'Telugu'), ('th', 'Thai'), ('tr', 'Turkish'), ('tt', 'Tatar'), ('udm', 'Udmurt'), ('uk', 'Ukrainian'), ('ur', 'Urdu'), ('vi', 'Vietnamese'), ('zh-hans', 'Simplified Chinese'), ('zh-hant', 'Traditional Chinese')]
LANGUAGES_BIDI	`['he', 'ar', 'fa', 'ur']`
LANGUAGE_CODE	`'en-us'`
LANGUAGE_COOKIE_AGE	`None`
LANGUAGE_COOKIE_DOMAIN	`None`
LANGUAGE_COOKIE_NAME	`'django_language'`
LANGUAGE_COOKIE_PATH	`'/'`
LOCALE_PATHS	`[]`
LOGGING	{'disable_existing_loggers': False, 'formatters': {'verbose': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s] %(message)s'}, 'verbose_low': {'datefmt': '%d/%b/%Y %H:%M:%S', 'format': '[%(asctime)s] %(levelname)s ' '[%(name)s:%(lineno)s]'}}, 'handlers': {'build': {'class': 'logging.FileHandler', 'filename': 'logs/build.log', 'formatter': 'verbose', 'level': 'DEBUG'}, 'django': {'class': 'logging.FileHandler', 'filename': 'logs/django.log', 'formatter': 'verbose', 'level': 'WARNING'}, 'protwis': {'class': 'logging.FileHandler', 'filename': 'logs/protwis.log', 'formatter': 'verbose', 'level': 'DEBUG'}}, 'loggers': {'build': {'handlers': ['build'], 'level': 'DEBUG'}, 'django': {'handlers': ['django'], 'level': 'WARNING', 'propagate': True}, 'protwis': {'handlers': ['protwis'], 'level': 'DEBUG'}}, 'version': 1}
LOGGING_CONFIG	`'logging.config.dictConfig'`
LOGIN_REDIRECT_URL	`'/accounts/profile/'`
LOGIN_URL	`'/accounts/login/'`
LOGOUT_REDIRECT_URL	`None`
MANAGERS	`[]`
MEDIA_ROOT	`'/protwis/media/protwis'`
MEDIA_URL	`'/media/'`
MESSAGE_STORAGE	`'django.contrib.messages.storage.fallback.FallbackStorage'`
MIDDLEWARE	`('common.middleware.stats.StatsMiddleware', 'debug_toolbar.middleware.DebugToolbarMiddleware', 'django.contrib.sessions.middleware.SessionMiddleware', 'django.middleware.common.CommonMiddleware', 'django.middleware.csrf.CsrfViewMiddleware', 'django.contrib.auth.middleware.AuthenticationMiddleware', 'django.contrib.messages.middleware.MessageMiddleware', 'django.middleware.clickjacking.XFrameOptionsMiddleware')`
MIGRATION_MODULES	`{}`
MONTH_DAY_FORMAT	`'F j'`
NUMBER_GROUPING	`0`
PASSWORD_HASHERS	`'********************'`
PASSWORD_RESET_TIMEOUT_DAYS	`'********************'`
PREPEND_WWW	`False`
REFERENCE_POSITIONS	`{'D1S1': 'D1S1x50', 'D1S2': 'D1S2x50', 'D1T1': 'D1T1x50', 'D1e1': 'D1e1x50', 'ECL1': '23x50', 'ECL2': '45x50', 'H8': '8x50', 'ICL1': '12x50', 'ICL2': '34x50', 'TM1': '1x50', 'TM2': '2x50', 'TM3': '3x50', 'TM4': '4x50', 'TM5': '5x50', 'TM6': '6x50', 'TM7': '7x50'}`
ROOT_URLCONF	`'protwis.urls'`
SECRET_KEY	`'********************'`
SECURE_BROWSER_XSS_FILTER	`False`
SECURE_CONTENT_TYPE_NOSNIFF	`False`
SECURE_HSTS_INCLUDE_SUBDOMAINS	`False`
SECURE_HSTS_PRELOAD	`False`
SECURE_HSTS_SECONDS	`0`
SECURE_PROXY_SSL_HEADER	`None`
SECURE_REDIRECT_EXEMPT	`[]`
SECURE_SSL_HOST	`None`
SECURE_SSL_REDIRECT	`False`
SERVER_EMAIL	`'root@localhost'`
SESSION_CACHE_ALIAS	`'default'`
SESSION_COOKIE_AGE	`86400`
SESSION_COOKIE_DOMAIN	`None`
SESSION_COOKIE_HTTPONLY	`True`
SESSION_COOKIE_NAME	`'sessionid'`
SESSION_COOKIE_PATH	`'/'`
SESSION_COOKIE_SAMESITE	`'Lax'`
SESSION_COOKIE_SECURE	`False`
SESSION_ENGINE	`'django.contrib.sessions.backends.db'`
SESSION_EXPIRE_AT_BROWSER_CLOSE	`False`
SESSION_FILE_PATH	`None`
SESSION_SAVE_EVERY_REQUEST	`False`
SESSION_SERIALIZER	`'django.contrib.sessions.serializers.PickleSerializer'`
SETTINGS_MODULE	`'protwis.settings'`
SHORT_DATETIME_FORMAT	`'m/d/Y P'`
SHORT_DATE_FORMAT	`'m/d/Y'`
SIGNING_BACKEND	`'django.core.signing.TimestampSigner'`
SILENCED_SYSTEM_CHECKS	`[]`
SITE_NAME	`'gpcr'`
SITE_TITLE	`'GPCRdb'`
STATICFILES_DIRS	`('/home/protwis/gpcrdb_test/static',)`
STATICFILES_FINDERS	`['django.contrib.staticfiles.finders.FileSystemFinder', 'django.contrib.staticfiles.finders.AppDirectoriesFinder']`
STATICFILES_STORAGE	`'django.contrib.staticfiles.storage.StaticFilesStorage'`
STATIC_ROOT	`'/home/protwis/static_test/'`
STATIC_URL	`'/static/'`
SWAGGER_SETTINGS	`{'USE_SESSION_AUTH': False}`
TEMPLATES	[{'APP_DIRS': True, 'BACKEND': 'django.template.backends.django.DjangoTemplates', 'DIRS': [], 'OPTIONS': {'context_processors': ['django.contrib.auth.context_processors.auth', 'django.template.context_processors.debug', 'django.template.context_processors.i18n', 'django.template.context_processors.media', 'django.template.context_processors.static', 'django.template.context_processors.tz', 'django.contrib.messages.context_processors.messages', 'protwis.context_processors.current_site', 'protwis.context_processors.canonical_tag', 'protwis.context_processors.documentation_url', 'protwis.context_processors.google_analytics', 'protwis.context_processors.site_title'], 'debug': True}}]
TEST_NON_SERIALIZED_APPS	`[]`
TEST_RUNNER	`'django.test.runner.DiscoverRunner'`
THOUSAND_SEPARATOR	`','`
TIME_FORMAT	`'P'`
TIME_INPUT_FORMATS	`['%H:%M:%S', '%H:%M:%S.%f', '%H:%M']`
TIME_ZONE	`'Europe/Copenhagen'`
USE_I18N	`True`
USE_L10N	`True`
USE_THOUSAND_SEPARATOR	`False`
USE_TZ	`True`
USE_X_FORWARDED_HOST	`False`
USE_X_FORWARDED_PORT	`False`
WSGI_APPLICATION	`None`
X_FRAME_OPTIONS	`'SAMEORIGIN'`
YEAR_MONTH_FORMAT	`'F Y'`

Key	Value
Accept	text/html,application/xhtml+xml,application/xml;q=0.9,/;q=0.8
Accept-Encoding	br,gzip
Accept-Language	en-US,en;q=0.5
Connection	close
Host	test.gpcrdb.org
If-Modified-Since	Sat, 03 Dec 2022 11:31:28 GMT
User-Agent	CCBot/2.0 (https://commoncrawl.org/faq/)
X-Forwarded-For	44.200.168.16
X-Forwarded-Proto	https
X-Real-Ip	44.200.168.16

Key	Value
Cache-Control	max-age=604800
Content-Length	127997
Content-Type	text/html; charset=utf-8
Expires	Thu, 30 Mar 2023 05:57:34 GMT
X-Frame-Options	SAMEORIGIN

Mutations

Versions

Time

Resource usage

Browser timing

Settings from `protwis.settings`

Headers

Request headers

Response headers

WSGI environ

Request

View information

No cookies

No session data

No GET data

No POST data

SQL queries from 0 connections

Static files (590 found, 0 used)

Static file path

Static file apps

Static files

django.contrib.staticfiles.finders.FileSystemFinder (415 files)

django.contrib.staticfiles.finders.AppDirectoriesFinder (175 files)

Templates (0 rendered)

Template paths

Templates

Context processors

Cache calls from 2 backends

Summary

Commands

Calls

Signals

Log messages

Key	Value
PATH_INFO	/construct/mutations
QUERY_STRING
REMOTE_ADDR
REQUEST_METHOD	GET
SCRIPT_NAME
SERVER_NAME	test.gpcrdb.org
SERVER_PORT	443
SERVER_PROTOCOL	HTTP/1.0
SERVER_SOFTWARE	gunicorn/19.9.0

Time (ms)		Type	Arguments	Keyword arguments	Backend
+	0.5870	get	('views.decorators.cache.cache_header..4d897a694136c44f27bb27149ac6c557.en-us.Europe/Copenhagen',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e908c6c18>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/middleware/cache.py in process_request(137) cache_key = get_cache_key(request, self.key_prefix, 'GET', cache=self.cache) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/utils/cache.py in get_cache_key(335) headerlist = cache.get(cache_key)
+	1.0285	get	('views.decorators.cache.cache_page..GET.4d897a694136c44f27bb27149ac6c557.d41d8cd98f00b204e9800998ecf8427e.en-us.Europe/Copenhagen',)	{}	<django.core.cache.backends.filebased.FileBasedCache object at 0x7f2e908c6c18>
	/usr/lib/python3.6/concurrent/futures/thread.py in _worker(69) work_item.run() /usr/lib/python3.6/concurrent/futures/thread.py in run(56) result = self.fn(self.args, *self.kwargs) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle(279) keepalive = self.handle_request(req, conn) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/gunicorn/workers/gthread.py in handle_request(328) respiter = self.wsgi(environ, resp.start_response) /home/protwis/gpcrdb_test/common/middleware/stats.py in __call__(34) response = self.get_response(request) /home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/middleware/cache.py in process_request(141) response = self.cache.get(cache_key)

Signal	Providing	Receivers
class_prepared	class
connection_created	connection
got_request_exception	request
post_delete	instance, using
post_init	instance
post_migrate	app_config, plan, interactive, verbosity, apps, using	create_permissions, create_contenttypes
post_save	created, raw, instance, update_fields, using
pre_delete	instance, using
pre_init	instance, args, kwargs
pre_save	instance, using, update_fields, raw
request_finished		close_old_connections, close_caches, reset_urlconf
request_started	environ	reset_queries, close_old_connections

Path	Location
visualization_scripts/maestro_label_generic_numbers.py	/home/protwis/gpcrdb_test/static/visualization_scripts/maestro_label_generic_numbers.py
visualization_scripts/pymol_view_generic_numbers.pml	/home/protwis/gpcrdb_test/static/visualization_scripts/pymol_view_generic_numbers.pml
bootstrap/js/npm.js	/home/protwis/gpcrdb_test/static/bootstrap/js/npm.js
bootstrap/js/bootstrap.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.js
bootstrap/js/bootstrap-submenu.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap-submenu.js
bootstrap/js/bootstrap.min.js	/home/protwis/gpcrdb_test/static/bootstrap/js/bootstrap.min.js
bootstrap/fonts/glyphicons-halflings-regular.eot	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.eot
bootstrap/fonts/glyphicons-halflings-regular.woff	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff
bootstrap/fonts/glyphicons-halflings-regular.ttf	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.ttf
bootstrap/fonts/glyphicons-halflings-regular.svg	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.svg
bootstrap/fonts/glyphicons-halflings-regular.woff2	/home/protwis/gpcrdb_test/static/bootstrap/fonts/glyphicons-halflings-regular.woff2
bootstrap/css/bootstrap.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css.map
bootstrap/css/bootstrap-submenu.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css
bootstrap/css/bootstrap.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.css
bootstrap/css/bootstrap-theme.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css.map
bootstrap/css/bootstrap-theme.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css.map
bootstrap/css/bootstrap-submenu.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.min.css
bootstrap/css/bootstrap.min.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css.map
bootstrap/css/bootstrap-submenu.css.map	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-submenu.css.map
bootstrap/css/bootstrap.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap.min.css
bootstrap/css/bootstrap-theme.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.css
bootstrap/css/bootstrap-theme.min.css	/home/protwis/gpcrdb_test/static/bootstrap/css/bootstrap-theme.min.css
blast/protwis_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psq
blast/protwis_human_bundle_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_bundle_blastdb.pin
blast/protwis_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pin
blast/protwis_human_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.phr
blast/protwis_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.psd
blast/protwis_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.phr
blast/protwis_human_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psq
blast/protwis_human_gpcr_blastdb.phr	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.phr
blast/protwis_human_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psq
blast/protwis_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psd
blast/protwis_human_blastdb.pin	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pin
blast/protwis_human_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.psd
blast/protwis_human_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_human_blastdb.pog
blast/.gitignore	/home/protwis/gpcrdb_test/static/blast/.gitignore
blast/protwis_human_gpcr_blastdb.psd	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psd
blast/protwis_blastdb.pog	/home/protwis/gpcrdb_test/static/blast/protwis_blastdb.pog
blast/protwis_gpcr_blastdb.psq	/home/protwis/gpcrdb_test/static/blast/protwis_gpcr_blastdb.psq
blast/protwis_human_gpcr_blastdb.psi	/home/protwis/gpcrdb_test/static/blast/protwis_human_gpcr_blastdb.psi

Path	Location
admin/js/cancel.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/cancel.js
admin/js/autocomplete.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/autocomplete.js
admin/js/collapse.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.min.js
admin/js/actions.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.min.js
admin/js/urlify.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/urlify.js
admin/js/popup_response.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/popup_response.js
admin/js/collapse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/collapse.js
admin/js/SelectBox.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectBox.js
admin/js/calendar.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/calendar.js
admin/js/actions.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/actions.js
admin/js/prepopulate.min.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/prepopulate.min.js
admin/js/SelectFilter2.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/SelectFilter2.js
admin/js/timeparse.js	/home/protwis/gpcrdb_env/lib/python3.6/site-packages/django/contrib/admin/static/admin/js/timeparse.js
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