This page shows a 2D t-SNE clustering algorithm embedding of GPCR similarity. Each point is a receptor; nearby points are more similar in the selected dataset.

• Dataset: switch between Sequence, Inactive structures, and Active structures.
• Human only: this view contains human receptors only.
• Structure datasets: include representative structures only (active/inactive sets).
• Colour by: recolours points by Class/Chemotype/Receptor family/Modality/Sense.
• Shape by: toggles marker shapes (None/Class). Note: choosing Colour by = Class forces Shape by = None; any other colour setting forces Shape by = Class.
• Hover any point to see details (e.g., label and UniProt).
• Legend: click legend items to exclude/include groups in the plot.