GPCRdb

mozavaptan

Agent/drug
Bioactivity

mozavaptan

SMILES	Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(N(C)C)c3ccccc32)cc1
InChIKey	WRNXUQJJCIZICJ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	427.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Drug Central GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

OT	OXYR	Human	Vasopressin and oxytocin	A	pKi	6.18	6.18	6.18	ChEMBL
OT	OXYR	Rat	Vasopressin and oxytocin	A	pKi	5.81	5.81	5.81	PDSP Ki database
OT	OXYR	Human	Vasopressin and oxytocin	A	pKi	8.21	8.21	8.21	Drug Central
V_1A	V1AR	Rat	Vasopressin and oxytocin	A	pKi	6.30	6.30	6.30	Guide to Pharmacology
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	6.71	6.71	6.71	ChEMBL
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	6.82	6.82	6.82	PDSP Ki database
V_1A	V1AR	Rat	Vasopressin and oxytocin	A	pKi	6.28	6.54	6.71	PDSP Ki database
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	8.17	8.17	8.17	Drug Central
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	6.80	6.95	7.10	Guide to Pharmacology
V_1B	V1BR	Human	Vasopressin and oxytocin	A	pKi	4.80	4.80	4.80	Guide to Pharmacology
V_1B	V1BR	Human	Vasopressin and oxytocin	A	pKi	5.00	5.00	5.00	PDSP Ki database
V_1B	V1BR	Human	Vasopressin and oxytocin	A	pKi	8.32	8.32	8.32	Drug Central
V_1B	V1BR	Rat	Vasopressin and oxytocin	A	pKi	5.00	5.00	5.00	PDSP Ki database
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	7.40	7.75	8.10	Guide to Pharmacology
V₂	V2R	Rat	Vasopressin and oxytocin	A	pKi	7.37	7.93	8.21	PDSP Ki database
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	8.03	8.03	8.03	PDSP Ki database
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	8.10	8.10	8.10	Drug Central
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	8.01	8.02	8.03	ChEMBL
V₂	V2R	Rat	Vasopressin and oxytocin	A	pKi	7.40	7.80	8.20	Guide to Pharmacology

Showing 1 to 19 of 19 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

V_1A	V1AR	Rat	Vasopressin and oxytocin	A	pIC50	5.85	5.85	5.85	ChEMBL
V_1A	V1AR	Rat	Vasopressin and oxytocin	A	pIC50	8.23	8.23	8.23	Drug Central
V₂	V2R	Rat	Vasopressin and oxytocin	A	pIC50	6.52	7.22	7.92	ChEMBL
V₂	V2R	Rat	Vasopressin and oxytocin	A	pIC50	8.10	8.10	8.10	Drug Central
V₂	V2R	Human	Vasopressin and oxytocin	A	pIC50	6.30	6.30	6.30	ChEMBL

Showing 1 to 5 of 5 entries

mozavaptan

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Drug Central GPCRdb

Compound is not listed as a drug.