ednrb_human
NAME
6IGK
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
ednrb_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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Q
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P
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P
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P
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S
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L
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C
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G
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R
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10 |
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A
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L
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V
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A
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L
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V
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L
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A
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C
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G
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20 |
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|
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L
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S
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R
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I
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W
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G
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E
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E
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R
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G
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30 |
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|
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F
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P
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P
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D
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R
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A
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T
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P
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L
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L
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40 |
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Q
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T
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A
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E
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I
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M
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T
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P
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P
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T
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50 |
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|
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K
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T
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L
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W
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P
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K
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G
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S
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N
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A
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60 |
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|||||
S
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L
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A
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R
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S
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L
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A
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P
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A
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E
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70 |
V
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P
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K
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G
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D
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R
|
T
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A
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G
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S
|
80 |
P
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P
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R
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T
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I
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S
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P
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P
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P
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C
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90 |
TM1 | |||||||||
Q
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G
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P
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I
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E
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I
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K
|
E
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T
|
F
|
100 |
K
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Y
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I
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N
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T
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V
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V
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S
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C
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L
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110 |
V
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F
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V
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L
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G
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I
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I
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G
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N
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S
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120 |
T
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L
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L
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R
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I
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I
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Y
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K
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N
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K
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130 |
ICL1 | TM2 | ||||||||
C
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M
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R
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N
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G
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P
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N
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I
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L
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I
|
140 |
A
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S
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L
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A
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L
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G
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D
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L
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L
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H
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150 |
I
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V
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I
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D
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I
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P
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I
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N
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V
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Y
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160 |
ECL1 | |||||||||
K
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L
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L
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A
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E
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D
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W
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P
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F
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G
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170 |
TM3 | |||||||||
A
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E
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M
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C
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K
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L
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V
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P
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F
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I
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180 |
Q
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K
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A
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S
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V
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G
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I
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T
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V
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L
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190 |
S
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L
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C
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A
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L
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S
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I
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D
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R
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Y
|
200 |
ICL2 | |||||||||
R
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A
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V
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A
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S
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W
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S
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R
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I
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K
|
210 |
TM4 | |||||||||
G
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I
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G
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V
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P
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K
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W
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T
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A
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V
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220 |
E
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I
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V
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L
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I
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W
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V
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V
|
S
|
V
|
230 |
V
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L
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A
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V
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P
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E
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A
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I
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G
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F
|
240 |
ECL2 | |||||||||
D
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I
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I
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T
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M
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D
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Y
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K
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G
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S
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250 |
Y
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L
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R
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I
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C
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L
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L
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H
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P
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V
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260 |
TM5 | |||||||||
Q
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K
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T
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A
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F
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M
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Q
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F
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Y
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K
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270 |
T
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A
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K
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D
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W
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W
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L
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F
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S
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F
|
280 |
Y
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F
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C
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L
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P
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L
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A
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I
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T
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A
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290 |
F
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F
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Y
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T
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L
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M
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T
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C
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E
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M
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300 |
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|||
L
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R
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K
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K
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S
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G
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M
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Q
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I
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A
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310 |
ICL3 | TM6 | ||||||||
L
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N
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D
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H
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L
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K
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Q
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R
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R
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E
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320 |
V
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A
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K
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T
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V
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F
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C
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L
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V
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L
|
330 |
V
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F
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A
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L
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C
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W
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L
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P
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L
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H
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340 |
L
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S
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R
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I
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L
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K
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L
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T
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L
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Y
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350 |
ECL3 | TM7 | ||||||||
N
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Q
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N
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D
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P
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N
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R
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C
|
E
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L
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360 |
L
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S
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F
|
L
|
L
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V
|
L
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D
|
Y
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I
|
370 |
G
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I
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N
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M
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A
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S
|
L
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N
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S
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C
|
380 |
I
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N
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P
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I
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A
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L
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Y
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L
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V
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S
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390 |
H8 | |||||||||
K
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R
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F
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K
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N
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C
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F
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K
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S
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C
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400 |
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|||||||
C-term | |||||||||
L
|
C
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C
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W
|
C
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Q
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S
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F
|
E
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E
|
410 |
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|
|
|
|
|
|
|
|
K
|
Q
|
S
|
L
|
E
|
E
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K
|
Q
|
S
|
C
|
420 |
|
|
|
|
|
|
|
|
|
|
L
|
K
|
F
|
K
|
A
|
N
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D
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H
|
G
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Y
|
430 |
|
|
|
|
|
|
|
|
|
|
D
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N
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F
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R
|
S
|
S
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N
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K
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Y
|
S
|
440 |
|
|
S
|
S
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Expression | ||||||||||
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|||||||||
N-term | |||||||||
|
L
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A
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P
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A
|
E
|
V
|
P
|
K
|
G
|
74 |
D
|
R
|
T
|
A
|
G
|
S
|
P
|
P
|
R
|
T
|
84 |
TM1 | |||||||||
I
|
S
|
P
|
P
|
P
|
C
|
Q
|
G
|
P
|
I
|
94 |
E
|
I
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K
|
E
|
T
|
F
|
K
|
Y
|
I
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N
|
104 |
T
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V
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V
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S
|
C
|
L
|
V
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F
|
V
|
L
|
114 |
G
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I
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I
|
G
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N
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S
|
T
|
L
|
L
|
R
|
124 |
ICL1 | |||||||||
I
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I
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Y
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K
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N
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K
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C
|
M
|
R
|
N
|
134 |
TM2 | |||||||||
G
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P
|
N
|
I
|
L
|
I
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A
|
S
|
L
|
A
|
144 |
L
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G
|
D
|
L
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L
|
H
|
I
|
V
|
I
|
D
|
154 |
I
|
P
|
I
|
N
|
V
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Y
|
K
|
L
|
L
|
A
|
164 |
ECL1 | TM3 | ||||||||
E
|
D
|
W
|
P
|
F
|
G
|
A
|
E
|
M
|
C
|
174 |
K
|
L
|
V
|
P
|
F
|
I
|
Q
|
K
|
A
|
S
|
184 |
V
|
G
|
I
|
T
|
V
|
L
|
S
|
L
|
C
|
A
|
194 |
L
|
S
|
I
|
D
|
R
|
Y
|
R
|
A
|
V
|
A
|
204 |
ICL2 | |||||||||
S
|
W
|
S
|
R
|
I
|
K
|
G
|
I
|
G
|
V
|
214 |
TM4 | |||||||||
P
|
K
|
W
|
T
|
A
|
V
|
E
|
I
|
V
|
L
|
224 |
I
|
W
|
V
|
V
|
S
|
V
|
V
|
L
|
A
|
V
|
234 |
ECL2 | |||||||||
P
|
E
|
A
|
I
|
G
|
F
|
D
|
I
|
I
|
T
|
244 |
M
|
D
|
Y
|
K
|
G
|
S
|
Y
|
L
|
R
|
I
|
254 |
C
|
L
|
L
|
H
|
P
|
V
|
Q
|
K
|
T
|
A
|
264 |
TM5 | |||||||||
F
|
M
|
Q
|
F
|
Y
|
K
|
T
|
A
|
K
|
D
|
274 |
W
|
W
|
L
|
F
|
S
|
F
|
Y
|
F
|
C
|
L
|
284 |
P
|
L
|
A
|
I
|
T
|
A
|
F
|
F
|
Y
|
T
|
294 |
|
|||||||||
L
|
M
|
T
|
C
|
E
|
M
|
L
|
R
|
K
|
|
ICL3 | TM6 | ||||||||
L
|
N
|
D
|
H
|
L
|
K
|
Q
|
R
|
R
|
E
|
320 |
V
|
A
|
K
|
T
|
V
|
F
|
C
|
L
|
V
|
L
|
330 |
V
|
F
|
A
|
L
|
C
|
W
|
L
|
P
|
L
|
H
|
340 |
L
|
S
|
R
|
I
|
L
|
K
|
L
|
T
|
L
|
Y
|
350 |
ECL3 | TM7 | ||||||||
N
|
Q
|
N
|
D
|
P
|
N
|
R
|
C
|
E
|
L
|
360 |
L
|
S
|
F
|
L
|
L
|
V
|
L
|
D
|
Y
|
I
|
370 |
G
|
I
|
N
|
M
|
A
|
S
|
L
|
N
|
S
|
C
|
380 |
I
|
N
|
P
|
I
|
A
|
L
|
Y
|
L
|
V
|
S
|
390 |
H8 | |||||||||
K
|
R
|
F
|
K
|
N
|
C
|
F
|
K
|
S
|
C
|
400 |
|
||||||||
C-term | ||||||||
L
|
C
|
C
|
W
|
C
|
Q
|
S
|
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
|
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
Protein_type: auto
Name: Expression tag
Sequence: None
Deletions:
Positions: N-term_0 None:None
Presence in Crystal:YES
Remarks: None
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|