gpr52_human
NAME
6LI1
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
gpr52_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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N
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E
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S
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R
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W
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T
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E
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W
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R
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10 |
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||||
I
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L
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N
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M
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S
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S
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G
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I
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V
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N
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20 |
V
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S
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E
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R
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H
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S
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C
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P
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L
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G
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30 |
F
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G
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H
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Y
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S
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V
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V
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D
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V
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C
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40 |
TM1 | |||||||||
I
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F
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E
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T
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V
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V
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I
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V
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L
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L
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50 |
T
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F
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L
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I
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I
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A
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G
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N
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L
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T
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60 |
V
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I
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F
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V
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F
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H
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C
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A
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P
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L
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70 |
ICL1 | TM2 | ||||||||
L
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H
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H
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Y
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T
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T
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S
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Y
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F
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I
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80 |
Q
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T
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M
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A
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Y
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A
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D
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L
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F
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V
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90 |
G
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V
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S
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C
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L
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V
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P
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T
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L
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S
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100 |
ECL1 | |||||||||
L
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L
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H
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Y
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S
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T
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G
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V
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H
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E
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110 |
TM3 | |||||||||
S
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L
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T
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C
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Q
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V
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F
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G
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Y
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I
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120 |
I
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S
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V
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L
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K
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S
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V
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S
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M
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A
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130 |
C
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L
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A
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C
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I
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S
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V
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D
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R
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Y
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140 |
ICL2 | |||||||||
L
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A
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I
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T
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K
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P
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L
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S
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Y
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N
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150 |
TM4 | |||||||||
Q
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L
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V
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T
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P
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C
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R
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L
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R
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I
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160 |
C
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I
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I
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L
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I
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W
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I
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Y
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S
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C
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170 |
L
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I
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F
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L
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P
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S
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F
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F
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G
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W
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180 |
ECL2 | |||||||||
G
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K
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P
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G
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Y
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H
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G
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D
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I
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F
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190 |
E
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W
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C
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A
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T
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S
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W
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L
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T
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S
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200 |
TM5 | |||||||||
A
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Y
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F
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T
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G
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F
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I
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V
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C
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L
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210 |
L
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Y
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A
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P
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A
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A
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F
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V
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V
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C
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220 |
F
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T
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Y
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F
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H
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I
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F
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K
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I
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C
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230 |
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||||||
R
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Q
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H
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T
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K
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E
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I
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N
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D
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R
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240 |
|
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ICL3 | |||||||||
R
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A
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R
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F
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P
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S
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H
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E
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V
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D
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250 |
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TM6 | |||||||||
S
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S
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R
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E
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T
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G
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H
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S
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P
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D
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260 |
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||||||
R
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R
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Y
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A
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M
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V
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L
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F
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R
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I
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270 |
T
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S
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V
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F
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Y
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M
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L
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W
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L
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P
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280 |
Y
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I
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I
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Y
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F
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L
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L
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E
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S
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S
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290 |
ECL3 | TM7 | ||||||||
R
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V
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L
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D
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N
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P
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T
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L
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S
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F
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300 |
L
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T
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T
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W
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L
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A
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I
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S
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N
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S
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310 |
F
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C
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N
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C
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V
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I
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Y
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S
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L
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S
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320 |
H8 | |||||||||
N
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S
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V
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F
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R
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L
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G
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L
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R
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R
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330 |
L
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S
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E
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T
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M
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C
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T
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S
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C
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M
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340 |
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C-term | |||||||||
C
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V
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K
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D
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Q
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E
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A
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Q
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E
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P
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350 |
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K
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P
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R
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K
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R
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A
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N
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S
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C
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S
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360 |
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I
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Expression | ||||||||||
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|||||||||
N-term | |||||||||
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G
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I
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V
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N
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V
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S
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E
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R
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H
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25 |
S
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C
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P
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L
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G
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F
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G
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H
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Y
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S
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35 |
TM1 | |||||||||
V
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V
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D
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V
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C
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I
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F
|
E
|
T
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V
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45 |
V
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I
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V
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L
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L
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T
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F
|
L
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I
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I
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55 |
A
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G
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N
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L
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T
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V
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I
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F
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V
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F
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65 |
ICL1 | |||||||||
H
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C
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A
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P
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L
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L
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H
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H
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Y
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T
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75 |
TM2 | |||||||||
T
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S
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Y
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F
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I
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Q
|
T
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M
|
A
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Y
|
85 |
A
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D
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L
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F
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V
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G
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V
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S
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C
|
L
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95 |
V
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P
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T
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L
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S
|
L
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L
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H
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Y
|
S
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105 |
ECL1 | TM3 | ||||||||
T
|
G
|
V
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H
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E
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S
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L
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T
|
C
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Q
|
115 |
V
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F
|
G
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Y
|
I
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I
|
S
|
V
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L
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K
|
125 |
S
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V
|
S
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M
|
A
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C
|
L
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A
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C
|
I
|
135 |
S
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V
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D
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R
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Y
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L
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A
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I
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T
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K
|
145 |
ICL2 | |||||||||
P
|
L
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S
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Y
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N
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Q
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L
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V
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T
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P
|
155 |
TM4 | |||||||||
C
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R
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L
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R
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I
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C
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I
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I
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L
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I
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165 |
W
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I
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Y
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S
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C
|
L
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I
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F
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L
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P
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175 |
ECL2 | |||||||||
S
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F
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F
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G
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W
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G
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K
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P
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G
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Y
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185 |
H
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G
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D
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I
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F
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E
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W
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C
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A
|
T
|
195 |
TM5 | |||||||||
S
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W
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L
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T
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S
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A
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Y
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F
|
T
|
G
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205 |
F
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I
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V
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C
|
L
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L
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Y
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A
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P
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A
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215 |
A
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F
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V
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V
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C
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F
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T
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Y
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F
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H
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225 |
I
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F
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K
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I
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C
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R
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Q
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H
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T
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K
|
235 |
|
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E
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Linker | |||||||||
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Flavodoxin | |||||||||
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TM6 | |||||||
M
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V
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L
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F
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R
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I
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T
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S
|
272 |
V
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F
|
Y
|
M
|
L
|
W
|
L
|
P
|
Y
|
I
|
282 |
I
|
Y
|
F
|
L
|
L
|
E
|
S
|
S
|
R
|
V
|
292 |
ECL3 | TM7 | ||||||||
L
|
D
|
N
|
P
|
T
|
L
|
S
|
F
|
L
|
T
|
302 |
T
|
W
|
L
|
A
|
I
|
S
|
N
|
S
|
F
|
C
|
312 |
H8 | |||||||||
N
|
C
|
V
|
I
|
Y
|
S
|
L
|
S
|
N
|
S
|
322 |
V
|
F
|
R
|
L
|
G
|
L
|
R
|
R
|
L
|
S
|
332 |
|
|||||||||
E
|
T
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M
|
C
|
T
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S
|
C
|
M
|
C
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
Protein_type: auto
Name: Expression tag
Sequence: None
Deletions:
Positions: N-term_0 None:None
Presence in Crystal:YES
Remarks: None
Protein_type: auto
Name: Linker
Sequence: None
Deletions:
Positions: Within Receptor_1 237:237
Presence in Crystal:YES
Remarks: None
Protein_type: fusion
Name: Flavodoxin
Sequence: None
Deletions:
Positions: Within Receptor_2 237:237
Presence in Crystal:YES
Remarks: None
Protein_type: auto
Name: Linker
Sequence: None
Deletions:
Positions: Within Receptor_3 237:237
Presence in Crystal:YES
Remarks: None
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
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SOLUBILIZATION
Solvent type | Item | Concentration |
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Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|