drd2_human
NAME
6LUQ
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
drd2_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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D
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P
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L
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N
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L
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S
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W
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Y
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D
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10 |
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D
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D
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L
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E
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R
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Q
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N
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W
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S
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R
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20 |
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P
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F
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N
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G
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S
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D
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G
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K
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A
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D
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30 |
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||||||
TM1 | |||||||||
R
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P
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H
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Y
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N
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Y
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Y
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A
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T
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L
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40 |
L
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T
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L
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L
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I
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A
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V
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I
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V
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F
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50 |
G
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N
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V
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L
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V
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C
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M
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A
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V
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S
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60 |
ICL1 | TM2 | ||||||||
R
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E
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K
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A
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L
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Q
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T
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T
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T
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N
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70 |
Y
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L
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I
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V
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S
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L
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A
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V
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A
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D
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80 |
L
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L
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V
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A
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T
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L
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V
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M
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P
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W
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90 |
V
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V
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Y
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L
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E
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V
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V
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G
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E
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W
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100 |
ECL1 | TM3 | ||||||||
K
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F
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S
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R
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I
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H
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C
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D
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I
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F
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110 |
V
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T
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L
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D
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V
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M
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M
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C
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T
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A
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120 |
S
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I
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L
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N
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L
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C
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A
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I
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S
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I
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130 |
D
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R
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Y
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T
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A
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V
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A
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M
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P
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M
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140 |
ICL2 | TM4 | ||||||||
L
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Y
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N
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T
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R
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Y
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S
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S
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K
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R
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150 |
R
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V
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T
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V
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M
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I
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S
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I
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V
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W
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160 |
V
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L
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S
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F
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T
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I
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S
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C
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P
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L
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170 |
ECL2 | |||||||||
L
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F
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G
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L
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N
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N
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A
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D
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Q
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N
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180 |
TM5 | |||||||||
E
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C
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I
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I
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A
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N
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P
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A
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F
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V
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190 |
V
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Y
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S
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S
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I
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V
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S
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F
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Y
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V
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200 |
P
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F
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I
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V
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T
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L
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L
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V
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Y
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I
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210 |
K
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I
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Y
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I
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V
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L
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R
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R
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R
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R
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220 |
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ICL3 | |||||||||
K
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R
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V
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N
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T
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K
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R
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S
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S
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R
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230 |
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A
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F
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R
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A
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H
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L
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R
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A
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P
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L
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240 |
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K
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G
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N
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C
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T
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H
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P
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E
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D
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M
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250 |
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K
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L
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C
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T
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V
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I
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M
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K
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S
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N
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260 |
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G
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S
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F
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P
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V
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N
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R
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R
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R
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V
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270 |
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E
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A
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A
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R
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R
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A
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Q
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E
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L
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E
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280 |
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M
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E
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M
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L
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S
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S
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T
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S
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P
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P
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290 |
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E
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R
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T
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R
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Y
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S
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P
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I
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P
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P
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300 |
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S
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H
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H
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Q
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L
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T
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L
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P
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D
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P
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310 |
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S
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H
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H
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G
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L
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H
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S
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T
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P
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D
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320 |
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S
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P
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A
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K
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P
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E
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K
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N
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G
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H
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330 |
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A
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K
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D
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H
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P
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K
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I
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A
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K
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I
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340 |
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F
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E
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I
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Q
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T
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M
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P
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N
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G
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K
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350 |
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T
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R
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T
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S
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L
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K
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T
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M
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S
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R
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360 |
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||||
TM6 | |||||||||
R
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K
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L
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S
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Q
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Q
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K
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E
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K
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K
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370 |
A
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T
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Q
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M
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L
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A
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I
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V
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L
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G
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380 |
V
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F
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I
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I
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C
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W
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L
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P
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F
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F
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390 |
I
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T
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H
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I
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L
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N
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I
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H
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C
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D
|
400 |
ECL3 | TM7 | ||||||||
C
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N
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I
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P
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P
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V
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L
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Y
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S
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A
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410 |
F
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T
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W
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L
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G
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Y
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V
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N
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S
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A
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420 |
V
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N
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P
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I
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I
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Y
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T
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T
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F
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N
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430 |
H8 | |||||||||
I
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E
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F
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R
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K
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A
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F
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L
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K
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I
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440 |
C-term | |||||||
L
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H
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C
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|||||
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|||||||||
TM1 | |||||||||
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N
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Y
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Y
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A
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T
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L
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L
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T
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L
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43 |
L
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I
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A
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V
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I
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V
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F
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G
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N
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V
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53 |
L
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V
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C
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M
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A
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V
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S
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R
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E
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K
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63 |
ICL1 | TM2 | ||||||||
A
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L
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Q
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T
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T
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T
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N
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Y
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L
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I
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73 |
V
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S
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L
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A
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V
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A
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D
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L
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L
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V
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83 |
A
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T
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L
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V
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M
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P
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W
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V
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V
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Y
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93 |
ECL1 | |||||||||
L
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E
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V
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V
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G
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E
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W
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K
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F
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S
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103 |
TM3 | |||||||||
R
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I
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H
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C
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D
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I
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F
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V
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T
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L
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113 |
D
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V
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M
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M
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C
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T
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A
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S
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I
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L
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123 |
N
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L
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C
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A
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I
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S
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I
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D
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R
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Y
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133 |
ICL2 | |||||||||
T
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A
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V
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A
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M
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P
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M
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L
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Y
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N
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143 |
TM4 | |||||||||
T
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R
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Y
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S
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S
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K
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R
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R
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V
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T
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153 |
V
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M
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I
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S
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I
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V
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W
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V
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L
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S
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163 |
F
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T
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I
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S
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C
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P
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L
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L
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F
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G
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173 |
ECL2 | |||||||||
L
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N
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N
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A
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D
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Q
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N
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E
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C
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I
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183 |
TM5 | |||||||||
I
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A
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N
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P
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A
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F
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V
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V
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Y
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S
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193 |
S
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I
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V
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S
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F
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Y
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V
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P
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F
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I
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203 |
V
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T
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L
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L
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V
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Y
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I
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K
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I
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Y
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213 |
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|||||||||
I
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V
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L
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R
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R
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R
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R
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K
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R
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T4 Lysozyme | ||||||||||
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TM6 | |||||||
K
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E
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K
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K
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A
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T
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Q
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M
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374 |
L
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A
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I
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V
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L
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G
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V
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F
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I
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I
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384 |
C
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W
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L
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P
|
F
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F
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I
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T
|
H
|
I
|
394 |
ECL3 | |||||||||
L
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N
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I
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H
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C
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D
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C
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N
|
I
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P
|
404 |
TM7 | |||||||||
P
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V
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L
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Y
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S
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A
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F
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T
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W
|
L
|
414 |
G
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Y
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V
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N
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S
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A
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V
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N
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P
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I
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424 |
H8 | |||||||||
I
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Y
|
T
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T
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F
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N
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I
|
E
|
F
|
R
|
434 |
K
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A
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F
|
L
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K
|
I
|
L
|
H
|
C
|
443 |
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
Protein_type: fusion
Name: T4 Lysozyme (T4L)
Sequence: None
Deletions:
Positions: Within Receptor_0 223:223
Presence in Crystal:YES
Remarks: None
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|