agtr1_human
NAME
6OS0
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
agtr1_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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I
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L
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N
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S
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S
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T
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E
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D
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G
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10 |
I
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K
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R
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I
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Q
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D
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D
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C
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P
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K
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20 |
TM1 | |||||||||
A
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G
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R
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H
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N
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Y
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I
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F
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V
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M
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30 |
I
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P
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T
|
L
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Y
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S
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I
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I
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F
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V
|
40 |
V
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G
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I
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F
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G
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N
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S
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L
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V
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V
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50 |
ICL1 | |||||||||
I
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V
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I
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Y
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F
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Y
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M
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K
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L
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K
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60 |
TM2 | |||||||||
T
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V
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A
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S
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V
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F
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L
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L
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N
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L
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70 |
A
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L
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A
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D
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L
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C
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F
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L
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L
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T
|
80 |
L
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P
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L
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W
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A
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V
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Y
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T
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A
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M
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90 |
ECL1 | TM3 | ||||||||
E
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Y
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R
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W
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P
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F
|
G
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N
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Y
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L
|
100 |
C
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K
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I
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A
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S
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A
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S
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V
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S
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F
|
110 |
N
|
L
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Y
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A
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S
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V
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F
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L
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L
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T
|
120 |
C
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L
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S
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I
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D
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R
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Y
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L
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A
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I
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130 |
ICL2 | |||||||||
V
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H
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P
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M
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K
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S
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R
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L
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R
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R
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140 |
TM4 | |||||||||
T
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M
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L
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V
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A
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K
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V
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T
|
C
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I
|
150 |
I
|
I
|
W
|
L
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L
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A
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G
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L
|
A
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S
|
160 |
L
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P
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A
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I
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I
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H
|
R
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N
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V
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F
|
170 |
ECL2 | |||||||||
F
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I
|
E
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N
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T
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N
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I
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T
|
V
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C
|
180 |
A
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F
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H
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Y
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E
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S
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Q
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N
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S
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T
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190 |
TM5 | |||||||||
L
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P
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I
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G
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L
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G
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L
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T
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K
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N
|
200 |
I
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L
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G
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F
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L
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F
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P
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F
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L
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I
|
210 |
I
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L
|
T
|
S
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Y
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T
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L
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I
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W
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K
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220 |
|
|||||||||
ICL3 | |||||||||
A
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L
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K
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K
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A
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Y
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E
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I
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Q
|
K
|
230 |
TM6 | |||||||||
N
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K
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P
|
R
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N
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D
|
D
|
I
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F
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K
|
240 |
I
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I
|
M
|
A
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I
|
V
|
L
|
F
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F
|
F
|
250 |
F
|
S
|
W
|
I
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P
|
H
|
Q
|
I
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F
|
T
|
260 |
F
|
L
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D
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V
|
L
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I
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Q
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L
|
G
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I
|
270 |
ECL3 | TM7 | ||||||||
I
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R
|
D
|
C
|
R
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I
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A
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D
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I
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V
|
280 |
D
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T
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A
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M
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P
|
I
|
T
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I
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C
|
I
|
290 |
A
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Y
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F
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N
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N
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C
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L
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N
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P
|
L
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300 |
H8 | |||||||||
F
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Y
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G
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F
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L
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G
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K
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K
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F
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K
|
310 |
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|||||||||
R
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Y
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F
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L
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Q
|
L
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L
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K
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Y
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I
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320 |
|
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C-term | |||||||||
P
|
P
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K
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A
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K
|
S
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H
|
S
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N
|
L
|
330 |
|
|
|
|
|
|
|
|
|
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S
|
T
|
K
|
M
|
S
|
T
|
L
|
S
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Y
|
R
|
340 |
|
|
|
|
|
|
|
|
|
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P
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S
|
D
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N
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V
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S
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S
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S
|
T
|
K
|
350 |
|
|
|
|
|
|
|
|
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K
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P
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A
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P
|
C
|
F
|
E
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V
|
E
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Expression | ||||||||||
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|||||||||
N-term | |||||||||
|
I
|
L
|
N
|
S
|
S
|
T
|
E
|
D
|
G
|
10 |
I
|
K
|
R
|
I
|
Q
|
D
|
D
|
C
|
P
|
K
|
20 |
TM1 | |||||||||
A
|
G
|
R
|
H
|
N
|
Y
|
I
|
F
|
V
|
M
|
30 |
I
|
P
|
T
|
L
|
Y
|
S
|
I
|
I
|
F
|
V
|
40 |
V
|
G
|
I
|
F
|
G
|
N
|
S
|
L
|
V
|
V
|
50 |
ICL1 | |||||||||
I
|
V
|
I
|
Y
|
F
|
Y
|
M
|
K
|
L
|
K
|
60 |
TM2 | |||||||||
T
|
V
|
A
|
S
|
V
|
F
|
L
|
L
|
N
|
L
|
70 |
A
|
L
|
A
|
D
|
L
|
C
|
F
|
L
|
L
|
T
|
80 |
L
|
P
|
L
|
W
|
A
|
V
|
Y
|
T
|
A
|
M
|
90 |
ECL1 | TM3 | ||||||||
E
|
Y
|
R
|
W
|
P
|
F
|
G
|
N
|
Y
|
L
|
100 |
C
|
K
|
I
|
A
|
S
|
A
|
S
|
V
|
S
|
F
|
110 |
N
|
L
|
Y
|
A
|
S
|
V
|
F
|
L
|
L
|
T
|
120 |
C
|
L
|
S
|
I
|
D
|
R
|
Y
|
L
|
A
|
I
|
130 |
ICL2 | |||||||||
V
|
H
|
P
|
M
|
K
|
S
|
R
|
L
|
R
|
R
|
140 |
TM4 | |||||||||
T
|
M
|
L
|
V
|
A
|
K
|
V
|
T
|
C
|
I
|
150 |
I
|
I
|
W
|
L
|
L
|
A
|
G
|
L
|
A
|
S
|
160 |
L
|
P
|
A
|
I
|
I
|
H
|
R
|
N
|
V
|
F
|
170 |
ECL2 | |||||||||
F
|
I
|
E
|
N
|
T
|
N
|
I
|
T
|
V
|
C
|
180 |
A
|
F
|
H
|
Y
|
E
|
S
|
Q
|
N
|
S
|
T
|
190 |
TM5 | |||||||||
L
|
P
|
I
|
G
|
L
|
G
|
L
|
T
|
K
|
N
|
200 |
I
|
L
|
G
|
F
|
L
|
F
|
P
|
F
|
L
|
I
|
210 |
I
|
L
|
T
|
S
|
Y
|
T
|
L
|
I
|
W
|
K
|
220 |
ICL3 | ||||||||
A
|
L
|
K
|
K
|
A
|
Y
|
|||
226 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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||||||||
TM6 | ||||||||
E
|
I
|
Q
|
K
|
N
|
K
|
P
|
R
|
N
|
235 |
D
|
D
|
I
|
F
|
K
|
I
|
I
|
M
|
A
|
I
|
245 |
V
|
L
|
F
|
F
|
F
|
F
|
S
|
W
|
I
|
P
|
255 |
H
|
Q
|
I
|
F
|
T
|
F
|
L
|
D
|
V
|
L
|
265 |
ECL3 | TM7 | |||||||||
I
|
Q
|
L
|
G
|
I
|
I
|
R
|
D
|
C
|
R
|
|
275 |
I
|
A
|
D
|
I
|
V
|
D
|
T
|
A
|
M
|
P
|
285 |
I
|
T
|
I
|
C
|
I
|
A
|
Y
|
F
|
N
|
N
|
295 |
C
|
L
|
N
|
P
|
L
|
F
|
Y
|
G
|
F
|
L
|
305 |
H8 | |||||||||
G
|
K
|
K
|
F
|
K
|
R
|
Y
|
F
|
L
|
Q
|
315 |
|
||||
L
|
L
|
K
|
Y
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
Protein_type: auto
Name: Expression tag
Sequence: None
Deletions:
Positions: N-term_0 None:None
Presence in Crystal:YES
Remarks: None
Protein_type: fusion
Name: BRIL (b562RIL)
Sequence: None
Deletions:
Positions: Within Receptor_1 227:227
Presence in Crystal:YES
Remarks: None
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|