oprd_human
NAME
6PT2
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
oprd_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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E
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P
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A
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P
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S
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A
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G
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A
|
E
|
10 |
|
|
|
|
|
|
|
|
|
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L
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Q
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P
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P
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L
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F
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A
|
N
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A
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S
|
20 |
|
|
|
|
|
|
|
|
|
|
D
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A
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Y
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P
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S
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A
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C
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P
|
S
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A
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30 |
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|
|
|
|
|
|
|
|
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G
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A
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N
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A
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S
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G
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P
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P
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G
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A
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40 |
TM1 | |||||||||
R
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S
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A
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S
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S
|
L
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A
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L
|
A
|
I
|
50 |
A
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I
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T
|
A
|
L
|
Y
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S
|
A
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V
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C
|
60 |
A
|
V
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G
|
L
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L
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G
|
N
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V
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L
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V
|
70 |
M
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F
|
G
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I
|
V
|
R
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Y
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T
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K
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M
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80 |
ICL1 | TM2 | ||||||||
K
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T
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A
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T
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N
|
I
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Y
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I
|
F
|
N
|
90 |
L
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A
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L
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A
|
D
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A
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L
|
A
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T
|
S
|
100 |
T
|
L
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P
|
F
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Q
|
S
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A
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K
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Y
|
L
|
110 |
ECL1 | TM3 | ||||||||
M
|
E
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T
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W
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P
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F
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G
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E
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L
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L
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120 |
C
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K
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A
|
V
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L
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S
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I
|
D
|
Y
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Y
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130 |
N
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M
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F
|
T
|
S
|
I
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F
|
T
|
L
|
T
|
140 |
M
|
M
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S
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V
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D
|
R
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Y
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I
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A
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V
|
150 |
ICL2 | |||||||||
C
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H
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P
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V
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K
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A
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L
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D
|
F
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R
|
160 |
TM4 | |||||||||
T
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P
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A
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K
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A
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K
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L
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I
|
N
|
I
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170 |
C
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I
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W
|
V
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L
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A
|
S
|
G
|
V
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G
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180 |
V
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P
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I
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M
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V
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M
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A
|
V
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T
|
R
|
190 |
ECL2 | |||||||||
P
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R
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D
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G
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A
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V
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V
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C
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M
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L
|
200 |
TM5 | |||||||||
Q
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F
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P
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S
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P
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S
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W
|
Y
|
W
|
D
|
210 |
T
|
V
|
T
|
K
|
I
|
C
|
V
|
F
|
L
|
F
|
220 |
A
|
F
|
V
|
V
|
P
|
I
|
L
|
I
|
I
|
T
|
230 |
V
|
C
|
Y
|
G
|
L
|
M
|
L
|
L
|
R
|
L
|
240 |
ICL3 | |||||||||
R
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S
|
V
|
R
|
L
|
L
|
S
|
G
|
S
|
K
|
250 |
TM6 | |||||||||
E
|
K
|
D
|
R
|
S
|
L
|
R
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R
|
I
|
T
|
260 |
R
|
M
|
V
|
L
|
V
|
V
|
V
|
G
|
A
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F
|
270 |
V
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V
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C
|
W
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A
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P
|
I
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H
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I
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F
|
280 |
V
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I
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V
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W
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T
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L
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V
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D
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I
|
D
|
290 |
ECL3 | TM7 | ||||||||
R
|
R
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D
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P
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L
|
V
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V
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A
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A
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L
|
300 |
H
|
L
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C
|
I
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A
|
L
|
G
|
Y
|
A
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N
|
310 |
S
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S
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L
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N
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P
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V
|
L
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Y
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A
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F
|
320 |
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|||||||||
H8 | |||||||||
L
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D
|
E
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N
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F
|
K
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R
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C
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F
|
R
|
330 |
|
|
|
|
|
|
|
|
|
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Q
|
L
|
C
|
R
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K
|
P
|
C
|
G
|
R
|
P
|
340 |
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|
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C-term | |||||||||
D
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P
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S
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S
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F
|
S
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R
|
A
|
R
|
E
|
350 |
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|
|
|
|
|
|
|
|
|
A
|
T
|
A
|
R
|
E
|
R
|
V
|
T
|
A
|
C
|
360 |
|
|
|
|
|
|
|
|
|
|
T
|
P
|
S
|
D
|
G
|
P
|
G
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G
|
G
|
A
|
370 |
|
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A
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A
|
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|||||||||
TM1 | |||||||||
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R
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S
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A
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S
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S
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L
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A
|
L
|
A
|
49 |
I
|
A
|
I
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T
|
A
|
L
|
Y
|
S
|
A
|
V
|
59 |
C
|
A
|
V
|
G
|
L
|
L
|
G
|
N
|
V
|
L
|
69 |
V
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M
|
F
|
G
|
I
|
V
|
R
|
Y
|
T
|
K
|
79 |
ICL1 | TM2 | ||||||||
M
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K
|
T
|
A
|
T
|
N
|
I
|
Y
|
I
|
F
|
89 |
N
|
L
|
A
|
L
|
A
|
D
|
A
|
L
|
A
|
T
|
99 |
S
|
T
|
L
|
P
|
F
|
Q
|
S
|
A
|
K
|
Y
|
109 |
ECL1 | TM3 | ||||||||
L
|
M
|
E
|
T
|
W
|
P
|
F
|
G
|
E
|
L
|
119 |
L
|
C
|
K
|
A
|
V
|
L
|
S
|
I
|
D
|
Y
|
129 |
Y
|
N
|
M
|
F
|
T
|
S
|
I
|
F
|
T
|
L
|
139 |
T
|
M
|
M
|
S
|
V
|
D
|
R
|
Y
|
I
|
A
|
149 |
ICL2 | |||||||||
V
|
C
|
H
|
P
|
V
|
K
|
A
|
L
|
D
|
F
|
159 |
TM4 | |||||||||
R
|
T
|
P
|
A
|
K
|
A
|
K
|
L
|
I
|
N
|
169 |
I
|
C
|
I
|
W
|
V
|
L
|
A
|
S
|
G
|
V
|
179 |
G
|
V
|
P
|
I
|
M
|
V
|
M
|
A
|
V
|
T
|
189 |
ECL2 | |||||||||
R
|
P
|
R
|
D
|
G
|
A
|
V
|
V
|
C
|
M
|
199 |
TM5 | |||||||||
L
|
Q
|
F
|
P
|
S
|
P
|
S
|
W
|
Y
|
W
|
209 |
D
|
T
|
V
|
T
|
K
|
I
|
C
|
V
|
F
|
L
|
219 |
F
|
A
|
F
|
V
|
V
|
P
|
I
|
L
|
I
|
I
|
229 |
T
|
V
|
C
|
Y
|
G
|
L
|
M
|
L
|
L
|
R
|
239 |
ICL3 | |||||||||
L
|
R
|
S
|
V
|
R
|
L
|
L
|
S
|
G
|
S
|
249 |
TM6 | |||||||||
K
|
E
|
K
|
D
|
R
|
S
|
L
|
R
|
R
|
I
|
259 |
T
|
R
|
M
|
V
|
L
|
V
|
V
|
V
|
G
|
A
|
269 |
F
|
V
|
V
|
C
|
W
|
A
|
P
|
I
|
H
|
I
|
279 |
F
|
V
|
I
|
V
|
W
|
T
|
L
|
V
|
D
|
I
|
289 |
ECL3 | TM7 | ||||||||
D
|
R
|
R
|
D
|
P
|
L
|
V
|
V
|
A
|
A
|
299 |
L
|
H
|
L
|
C
|
I
|
A
|
L
|
G
|
Y
|
A
|
309 |
N
|
S
|
S
|
L
|
N
|
P
|
V
|
L
|
Y
|
A
|
319 |
|
|||||||||||||||||||||
H8 | |||||||||||||||||||||
F
|
L
|
D
|
E
|
N
|
F
|
K
|
R
|
C
|
F
|
|
|||||||||||
329 |
SCHEMATIC
Perspective:
Wild-type
Construct
|
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|