agrg3_human
NAME
7D77
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
agrg3_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
|
|
||||||||
N-term | |||||||||
M
|
A
|
T
|
P
|
R
|
G
|
L
|
G
|
A
|
L
|
10 |
L
|
L
|
L
|
L
|
L
|
L
|
P
|
T
|
S
|
G
|
20 |
Q
|
E
|
K
|
P
|
T
|
E
|
G
|
P
|
R
|
N
|
30 |
T
|
C
|
L
|
G
|
S
|
N
|
N
|
M
|
Y
|
D
|
40 |
I
|
F
|
N
|
L
|
N
|
D
|
K
|
A
|
L
|
C
|
50 |
F
|
T
|
K
|
C
|
R
|
Q
|
S
|
G
|
S
|
D
|
60 |
S
|
C
|
N
|
V
|
E
|
N
|
L
|
Q
|
R
|
Y
|
70 |
W
|
L
|
N
|
Y
|
E
|
A
|
H
|
L
|
M
|
K
|
80 |
E
|
G
|
L
|
T
|
Q
|
K
|
V
|
N
|
T
|
P
|
90 |
F
|
L
|
K
|
A
|
L
|
V
|
Q
|
N
|
L
|
S
|
100 |
T
|
N
|
T
|
A
|
E
|
D
|
F
|
Y
|
F
|
S
|
110 |
L
|
E
|
P
|
S
|
Q
|
V
|
P
|
R
|
Q
|
V
|
120 |
M
|
K
|
D
|
E
|
D
|
K
|
P
|
P
|
D
|
R
|
130 |
V
|
R
|
L
|
P
|
K
|
S
|
L
|
F
|
R
|
S
|
140 |
L
|
P
|
G
|
N
|
R
|
S
|
V
|
V
|
R
|
L
|
150 |
A
|
V
|
T
|
I
|
L
|
D
|
I
|
G
|
P
|
G
|
160 |
T
|
L
|
F
|
K
|
G
|
P
|
R
|
L
|
G
|
L
|
170 |
G
|
D
|
G
|
S
|
G
|
V
|
L
|
N
|
N
|
R
|
180 |
L
|
V
|
G
|
L
|
S
|
V
|
G
|
Q
|
M
|
H
|
190 |
V
|
T
|
K
|
L
|
A
|
E
|
P
|
L
|
E
|
I
|
200 |
V
|
F
|
S
|
H
|
Q
|
R
|
P
|
P
|
P
|
N
|
210 |
M
|
T
|
L
|
T
|
C
|
V
|
F
|
W
|
D
|
V
|
220 |
T
|
K
|
G
|
T
|
T
|
G
|
D
|
W
|
S
|
S
|
230 |
E
|
G
|
C
|
S
|
T
|
E
|
V
|
R
|
P
|
E
|
240 |
G
|
T
|
V
|
C
|
C
|
C
|
D
|
H
|
L
|
T
|
250 |
F
|
F
|
A
|
L
|
L
|
L
|
R
|
P
|
T
|
L
|
260 |
TM1 | |||||||||
D
|
Q
|
S
|
T
|
V
|
H
|
I
|
L
|
T
|
R
|
270 |
I
|
S
|
Q
|
A
|
G
|
C
|
G
|
V
|
S
|
M
|
280 |
I
|
F
|
L
|
A
|
F
|
T
|
I
|
I
|
L
|
Y
|
290 |
A
|
F
|
L
|
R
|
L
|
S
|
R
|
E
|
R
|
F
|
300 |
ICL1 | TM2 | ||||||||
K
|
S
|
E
|
D
|
A
|
P
|
K
|
I
|
H
|
V
|
310 |
A
|
L
|
G
|
G
|
S
|
L
|
F
|
L
|
L
|
N
|
320 |
L
|
A
|
F
|
L
|
V
|
N
|
V
|
G
|
S
|
G
|
330 |
ECL1 | TM3 | ||||||||
S
|
K
|
G
|
S
|
D
|
A
|
A
|
C
|
W
|
A
|
340 |
R
|
G
|
A
|
V
|
F
|
H
|
Y
|
F
|
L
|
L
|
350 |
|
|
|
|
|
|
||||
C
|
A
|
F
|
T
|
W
|
M
|
G
|
L
|
E
|
A
|
360 |
|
|
|
|
|
|
|
|
|
|
F
|
H
|
L
|
Y
|
L
|
L
|
A
|
V
|
R
|
V
|
370 |
|
|
|
|
|
|
|
|
|
|
ICL2 | TM4 | ||||||||
F
|
N
|
T
|
Y
|
F
|
G
|
H
|
Y
|
F
|
L
|
380 |
|
|
|
|
|
|
|
|
|
|
K
|
L
|
S
|
L
|
V
|
G
|
W
|
G
|
L
|
P
|
390 |
|
|
|
|
|
|
|
|
|
|
A
|
L
|
M
|
V
|
I
|
G
|
T
|
G
|
S
|
A
|
400 |
|
|
|
|
|
|
|
|
|
|
ECL2 | |||||||||
N
|
S
|
Y
|
G
|
L
|
Y
|
T
|
I
|
R
|
D
|
410 |
|
|
|
|
|
|
|
|
|
|
R
|
E
|
N
|
R
|
T
|
S
|
L
|
E
|
L
|
C
|
420 |
|
|
|
|
|
|
|
|
|
|
W
|
F
|
R
|
E
|
G
|
T
|
T
|
M
|
Y
|
A
|
430 |
|
|
|
|
|
|
|
|
|
|
TM5 | |||||||||
L
|
Y
|
I
|
T
|
V
|
H
|
G
|
Y
|
F
|
L
|
440 |
|
|
|
|
|
|
|
|
|
|
I
|
T
|
F
|
L
|
F
|
G
|
M
|
V
|
V
|
L
|
450 |
|
|
|
|
|
|
|
|
|
|
A
|
L
|
V
|
V
|
W
|
K
|
I
|
F
|
T
|
L
|
460 |
|
|
|
|
|
|
|
|
|
|
ICL3 | |||||||||
S
|
R
|
A
|
T
|
A
|
V
|
K
|
E
|
R
|
G
|
470 |
|
|
|
|
|
|
|
|
|
|
TM6 | |||||||||
K
|
N
|
R
|
K
|
K
|
V
|
L
|
T
|
L
|
L
|
480 |
|
|
|
|
|
|
|
|
|
|
G
|
L
|
S
|
S
|
L
|
V
|
G
|
V
|
T
|
W
|
490 |
|
|
|
|
|
|
|
|
|
|
ECL3 | |||||||||
G
|
L
|
A
|
I
|
F
|
T
|
P
|
L
|
G
|
L
|
500 |
|
|
|
|
|
|
|
|
|
|
TM7 | |||||||||
S
|
T
|
V
|
Y
|
I
|
F
|
A
|
L
|
F
|
N
|
510 |
|
|
|
|
|
|
|
|
|
|
S
|
L
|
Q
|
G
|
V
|
F
|
I
|
C
|
C
|
W
|
520 |
|
|
|
|
|
|
|
|
|
|
F
|
T
|
I
|
L
|
Y
|
L
|
P
|
S
|
Q
|
S
|
530 |
|
|
|
|
|
|
|
|
|
|
C-term | |||||||||
T
|
T
|
V
|
S
|
S
|
S
|
T
|
A
|
R
|
L
|
540 |
|
|
|
|
|
|
|
|
|
D
|
Q
|
A
|
H
|
S
|
A
|
S
|
Q
|
E
|
|
|||||||||
N-term | |||||||||
|
T
|
P
|
R
|
G
|
L
|
G
|
A
|
L
|
L
|
11 |
L
|
L
|
L
|
L
|
L
|
P
|
T
|
S
|
G
|
Q
|
21 |
E
|
K
|
P
|
T
|
E
|
G
|
P
|
R
|
N
|
T
|
31 |
C
|
L
|
G
|
S
|
N
|
N
|
M
|
Y
|
D
|
I
|
41 |
F
|
N
|
L
|
N
|
D
|
K
|
A
|
L
|
C
|
F
|
51 |
T
|
K
|
C
|
R
|
Q
|
S
|
G
|
S
|
D
|
S
|
61 |
C
|
N
|
V
|
E
|
N
|
L
|
Q
|
R
|
Y
|
W
|
71 |
L
|
N
|
Y
|
E
|
A
|
H
|
L
|
M
|
K
|
E
|
81 |
G
|
L
|
T
|
Q
|
K
|
V
|
N
|
T
|
P
|
F
|
91 |
L
|
K
|
A
|
L
|
V
|
Q
|
N
|
L
|
S
|
T
|
101 |
N
|
T
|
A
|
E
|
D
|
F
|
Y
|
F
|
S
|
L
|
111 |
E
|
P
|
S
|
Q
|
V
|
P
|
R
|
Q
|
V
|
M
|
121 |
K
|
D
|
E
|
D
|
K
|
P
|
P
|
D
|
R
|
V
|
131 |
R
|
L
|
P
|
K
|
S
|
L
|
F
|
R
|
S
|
L
|
141 |
P
|
G
|
N
|
R
|
S
|
V
|
V
|
R
|
L
|
A
|
151 |
V
|
T
|
I
|
L
|
D
|
I
|
G
|
P
|
G
|
T
|
161 |
L
|
F
|
K
|
G
|
P
|
R
|
L
|
G
|
L
|
G
|
171 |
D
|
G
|
S
|
G
|
V
|
L
|
N
|
N
|
R
|
L
|
181 |
V
|
G
|
L
|
S
|
V
|
G
|
Q
|
M
|
H
|
V
|
191 |
T
|
K
|
L
|
A
|
E
|
P
|
L
|
E
|
I
|
V
|
201 |
F
|
S
|
H
|
Q
|
R
|
P
|
P
|
P
|
N
|
M
|
211 |
T
|
L
|
T
|
C
|
V
|
F
|
W
|
D
|
V
|
T
|
221 |
K
|
G
|
T
|
T
|
G
|
D
|
W
|
S
|
S
|
E
|
231 |
G
|
C
|
S
|
T
|
E
|
V
|
R
|
P
|
E
|
G
|
241 |
T
|
V
|
C
|
C
|
C
|
D
|
H
|
L
|
T
|
F
|
251 |
F
|
A
|
L
|
L
|
L
|
R
|
P
|
T
|
L
|
D
|
261 |
TM1 | |||||||||
Q
|
S
|
T
|
V
|
H
|
I
|
L
|
T
|
R
|
I
|
271 |
S
|
Q
|
A
|
G
|
C
|
G
|
V
|
S
|
M
|
I
|
281 |
F
|
L
|
A
|
F
|
T
|
I
|
I
|
L
|
Y
|
A
|
291 |
ICL1 | |||||||||
F
|
L
|
R
|
L
|
S
|
R
|
E
|
R
|
F
|
K
|
301 |
TM2 | |||||||||
S
|
E
|
D
|
A
|
P
|
K
|
I
|
H
|
V
|
A
|
311 |
L
|
G
|
G
|
S
|
L
|
F
|
L
|
L
|
N
|
L
|
321 |
A
|
F
|
L
|
V
|
N
|
V
|
G
|
S
|
G
|
S
|
331 |
ECL1 | TM3 | ||||||||
K
|
G
|
S
|
D
|
A
|
A
|
C
|
W
|
A
|
R
|
341 |
G
|
A
|
V
|
F
|
H
|
Y
|
F
|
L
|
L
|
C
|
351 |
|
|||
A
|
F
|
T
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|