pe2r4_human
NAME
7D7M
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
pe2r4_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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S
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T
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P
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G
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V
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N
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S
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S
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A
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10 |
TM1 | |||||||||
S
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L
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S
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P
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D
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R
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L
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N
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S
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P
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20 |
V
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T
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I
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P
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A
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V
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M
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F
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I
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F
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30 |
G
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V
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V
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G
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N
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L
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V
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A
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I
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V
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40 |
ICL1 | |||||||||
V
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L
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C
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K
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S
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R
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K
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E
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Q
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K
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50 |
TM2 | |||||||||
E
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T
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T
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F
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Y
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T
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L
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V
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C
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G
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60 |
L
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A
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V
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T
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D
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L
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L
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G
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T
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L
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70 |
L
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V
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S
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P
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V
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T
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I
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A
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T
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Y
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80 |
ECL1 | TM3 | ||||||||
M
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K
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G
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Q
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W
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P
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G
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G
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Q
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P
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90 |
L
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C
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E
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Y
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S
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T
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F
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I
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L
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L
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100 |
F
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F
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S
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L
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S
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G
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L
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S
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I
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I
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110 |
C
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A
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M
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S
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V
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E
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R
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Y
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L
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A
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120 |
ICL2 | |||||||||
I
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N
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H
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A
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Y
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F
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Y
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S
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H
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Y
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130 |
TM4 | |||||||||
V
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D
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K
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R
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L
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A
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G
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L
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T
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L
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140 |
F
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A
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V
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Y
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A
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S
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N
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V
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L
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F
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150 |
C
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A
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L
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P
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N
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M
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G
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L
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G
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S
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160 |
ECL2 | |||||||||
S
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R
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L
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Q
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Y
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P
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D
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T
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W
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C
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170 |
TM5 | |||||||||
F
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I
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D
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W
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T
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T
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N
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V
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T
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A
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180 |
H
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A
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A
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Y
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S
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Y
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M
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Y
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A
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G
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190 |
F
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S
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S
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F
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L
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I
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L
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A
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T
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V
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200 |
L
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C
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N
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V
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L
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V
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C
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G
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A
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L
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210 |
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|||||||
L
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R
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M
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H
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R
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Q
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F
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M
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R
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R
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220 |
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ICL3 | |||||||||
T
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S
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L
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G
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T
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E
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Q
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H
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H
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A
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230 |
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A
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A
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A
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A
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S
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V
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A
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S
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R
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G
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240 |
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H
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P
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A
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A
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S
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P
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A
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L
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P
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R
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250 |
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L
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S
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D
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F
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R
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R
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R
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R
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S
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F
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260 |
TM6 | |||||||||
R
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R
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I
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A
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G
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A
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E
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I
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Q
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M
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270 |
V
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I
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L
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L
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I
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A
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T
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S
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L
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V
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280 |
V
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P
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L
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V
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V
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290 |
R
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V
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F
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V
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N
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Q
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L
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Y
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Q
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P
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300 |
ECL3 | |||||||||
S
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L
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E
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R
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E
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V
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S
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K
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N
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P
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310 |
TM7 | |||||||||
D
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L
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Q
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A
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I
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R
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I
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A
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S
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V
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320 |
N
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P
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I
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L
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D
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P
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W
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I
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Y
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I
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330 |
H8 | |||||||||
L
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L
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R
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K
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T
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V
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L
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S
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K
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A
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340 |
I
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E
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K
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I
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K
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C
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L
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F
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C
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R
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350 |
C-term | |||||||||
I
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G
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G
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S
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R
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R
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E
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R
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S
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G
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360 |
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Q
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H
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C
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S
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D
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S
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Q
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R
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T
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S
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370 |
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A
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M
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S
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G
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H
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S
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R
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F
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380 |
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L
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K
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S
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390 |
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T
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Q
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T
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L
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L
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P
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D
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L
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S
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400 |
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L
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P
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D
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L
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S
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N
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G
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L
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G
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410 |
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G
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R
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N
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L
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L
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P
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G
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V
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P
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G
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420 |
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M
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G
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L
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A
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Q
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D
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T
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T
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S
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430 |
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L
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T
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L
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I
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T
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S
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440 |
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D
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S
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Q
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G
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Q
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D
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S
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S
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450 |
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V
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L
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L
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V
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D
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E
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A
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G
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G
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S
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460 |
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G
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R
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A
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G
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P
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A
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P
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K
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G
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S
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470 |
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S
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L
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Q
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V
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T
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F
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P
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S
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E
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T
|
480 |
|
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|
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|
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L
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N
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L
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S
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E
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K
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C
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I
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|||||||||
N-term | |||||||||
|
P
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G
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V
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N
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S
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S
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A
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S
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L
|
12 |
TM1 | |||||||||
S
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P
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D
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R
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L
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N
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S
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P
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V
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T
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22 |
I
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P
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A
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V
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M
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F
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I
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F
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G
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V
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32 |
V
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G
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N
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L
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V
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A
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I
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V
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V
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L
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42 |
ICL1 | |||||||||
C
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K
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S
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R
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K
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E
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Q
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K
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E
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T
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52 |
TM2 | |||||||||
T
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F
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Y
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T
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L
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V
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C
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G
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L
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A
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62 |
V
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T
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D
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L
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L
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G
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T
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L
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L
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V
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72 |
S
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P
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V
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T
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I
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A
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T
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Y
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M
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K
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82 |
ECL1 | TM3 | ||||||||
G
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Q
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W
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P
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G
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G
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Q
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P
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L
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C
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92 |
E
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Y
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S
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T
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F
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I
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L
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L
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F
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F
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102 |
S
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L
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S
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G
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L
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S
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I
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I
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C
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A
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112 |
M
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S
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V
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E
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R
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Y
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L
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A
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I
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N
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122 |
ICL2 | |||||||||
H
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A
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Y
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F
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Y
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S
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H
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Y
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V
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D
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132 |
TM4 | |||||||||
K
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R
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L
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A
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G
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L
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T
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L
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F
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A
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142 |
V
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Y
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A
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S
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N
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V
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L
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F
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C
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A
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152 |
ECL2 | |||||||||
L
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P
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N
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M
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G
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L
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G
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S
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S
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R
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162 |
L
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Q
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Y
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P
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D
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T
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W
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C
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F
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I
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172 |
TM5 | |||||||||
D
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W
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T
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T
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N
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V
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T
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A
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H
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A
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182 |
A
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Y
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S
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Y
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M
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Y
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A
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G
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F
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S
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192 |
S
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F
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L
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I
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L
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A
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T
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V
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L
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C
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202 |
N
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V
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L
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V
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C
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G
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A
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L
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L
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R
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212 |
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||||||||||||
ICL3 | TM6 | |||||||||||
M
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H
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R
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Q
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F
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F
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R
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R
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I
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|||
263 |
A
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G
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A
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E
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I
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Q
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M
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V
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I
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L
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273 |
L
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I
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A
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T
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S
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L
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V
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V
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L
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I
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283 |
C
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S
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I
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P
|
L
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V
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V
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R
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V
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F
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293 |
ECL3 | |||||||||
V
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N
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Q
|
L
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Y
|
Q
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P
|
S
|
L
|
E
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303 |
TM7 | |||||||||
R
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E
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V
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S
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K
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N
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P
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D
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L
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Q
|
313 |
A
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I
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R
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I
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A
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S
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V
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N
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P
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I
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323 |
L
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D
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P
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W
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I
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Y
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I
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L
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L
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R
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333 |
H8 | |||||||||
K
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T
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V
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L
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S
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K
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A
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I
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E
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K
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343 |
C-term | |||||||||
I
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K
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C
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L
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F
|
C
|
R
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I
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G
|
G
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353 |
S
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R
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R
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E
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R
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S
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G
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Q
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H
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C
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363 |
|
|||
S
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D
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S
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SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
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Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|