agrg5_human
NAME
7EQ1
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
agrg5_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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D
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H
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C
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G
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A
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L
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F
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L
|
C
|
10 |
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|
|
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|
|
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L
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C
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L
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L
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T
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L
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Q
|
N
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A
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T
|
20 |
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|
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|
|
|
|
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T
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E
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T
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W
|
E
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E
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L
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L
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S
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Y
|
30 |
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|
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|
|
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M
|
E
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N
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M
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Q
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V
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S
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R
|
G
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R
|
40 |
|
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|
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|
|
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S
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S
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V
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F
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S
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S
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R
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Q
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L
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H
|
50 |
|
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|
|
|
|
|
|
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Q
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L
|
E
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Q
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M
|
L
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L
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N
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T
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S
|
60 |
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|
|
|
|
|
|
|
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F
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P
|
G
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Y
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N
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L
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T
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L
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Q
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T
|
70 |
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|
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|
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|
|
|
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P
|
T
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I
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Q
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S
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L
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A
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F
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K
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L
|
80 |
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|
|
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|
|
|
|
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S
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C
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D
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F
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S
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G
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L
|
S
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L
|
T
|
90 |
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|
|
|
|
|
|
|
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S
|
A
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T
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L
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K
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R
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V
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P
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Q
|
A
|
100 |
|
|
|
|
|
|
|
|
|
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G
|
G
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Q
|
H
|
A
|
R
|
G
|
Q
|
H
|
A
|
110 |
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|
|
|
|
|
|
|
|
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M
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Q
|
F
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P
|
A
|
E
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L
|
T
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R
|
D
|
120 |
|
|
|
|
|
|
|
|
|
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A
|
C
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K
|
T
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R
|
P
|
R
|
E
|
L
|
R
|
130 |
|
|
|
|
|
|
|
|
|
|
L
|
I
|
C
|
I
|
Y
|
F
|
S
|
N
|
T
|
H
|
140 |
|
|
|
|
|
|
|
|
|
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F
|
F
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K
|
D
|
E
|
N
|
N
|
S
|
S
|
L
|
150 |
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|
|
|
|
|
|
|
|
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L
|
N
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N
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Y
|
V
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L
|
G
|
A
|
Q
|
L
|
160 |
|
|
|
|
|
|
|
|
|
|
S
|
H
|
G
|
H
|
V
|
N
|
N
|
L
|
R
|
D
|
170 |
|
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|
|
|
|
|
|
|
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P
|
V
|
N
|
I
|
S
|
F
|
W
|
H
|
N
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Q
|
180 |
|
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|
|
|
|
|
|
|
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S
|
L
|
E
|
G
|
Y
|
T
|
L
|
T
|
C
|
V
|
190 |
|
|
|
|
|
|
|
|
|
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F
|
W
|
K
|
E
|
G
|
A
|
R
|
K
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Q
|
P
|
200 |
|
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|
|
|
|
|
|
|
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W
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G
|
G
|
W
|
S
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P
|
E
|
G
|
C
|
R
|
210 |
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|
|
|
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|
|
|
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T
|
E
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Q
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P
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S
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H
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S
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Q
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V
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L
|
220 |
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||||
C
|
R
|
C
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N
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H
|
L
|
T
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Y
|
F
|
A
|
230 |
V
|
L
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M
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Q
|
L
|
S
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P
|
A
|
L
|
V
|
240 |
TM1 | |||||||||
P
|
A
|
E
|
L
|
L
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A
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P
|
L
|
T
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Y
|
250 |
I
|
S
|
L
|
V
|
G
|
C
|
S
|
I
|
S
|
I
|
260 |
V
|
A
|
S
|
L
|
I
|
T
|
V
|
L
|
L
|
H
|
270 |
ICL1 | TM2 | ||||||||
F
|
H
|
F
|
R
|
K
|
Q
|
S
|
D
|
S
|
L
|
280 |
T
|
R
|
I
|
H
|
M
|
N
|
L
|
H
|
A
|
S
|
290 |
V
|
L
|
L
|
L
|
N
|
I
|
A
|
F
|
L
|
L
|
300 |
ECL1 | |||||||||
S
|
P
|
A
|
F
|
A
|
M
|
S
|
P
|
V
|
P
|
310 |
TM3 | |||||||||
G
|
S
|
A
|
C
|
T
|
A
|
L
|
A
|
A
|
A
|
320 |
L
|
H
|
Y
|
A
|
L
|
L
|
S
|
C
|
L
|
T
|
330 |
W
|
M
|
A
|
I
|
E
|
G
|
F
|
N
|
L
|
Y
|
340 |
ICL2 | |||||||||
L
|
L
|
L
|
G
|
R
|
V
|
Y
|
N
|
I
|
Y
|
350 |
TM4 | |||||||||
I
|
R
|
R
|
Y
|
V
|
F
|
K
|
L
|
G
|
V
|
360 |
L
|
G
|
W
|
G
|
A
|
P
|
A
|
L
|
L
|
V
|
370 |
L
|
L
|
S
|
L
|
S
|
V
|
K
|
S
|
S
|
V
|
380 |
ECL2 | |||||||||
Y
|
G
|
P
|
C
|
T
|
I
|
P
|
V
|
F
|
D
|
390 |
S
|
W
|
E
|
N
|
G
|
T
|
G
|
F
|
Q
|
N
|
400 |
TM5 | |||||||||
M
|
S
|
I
|
C
|
W
|
V
|
R
|
S
|
P
|
V
|
410 |
V
|
H
|
S
|
V
|
L
|
V
|
M
|
G
|
Y
|
G
|
420 |
G
|
L
|
T
|
S
|
L
|
F
|
N
|
L
|
V
|
V
|
430 |
L
|
A
|
W
|
A
|
L
|
W
|
T
|
L
|
R
|
R
|
440 |
ICL3 | |||||||||
L
|
R
|
E
|
R
|
A
|
D
|
A
|
P
|
S
|
V
|
450 |
TM6 | |||||||||
R
|
A
|
C
|
H
|
D
|
T
|
V
|
T
|
V
|
L
|
460 |
G
|
L
|
T
|
V
|
L
|
L
|
G
|
T
|
T
|
W
|
470 |
A
|
L
|
A
|
F
|
F
|
S
|
F
|
G
|
V
|
F
|
480 |
ECL3 | TM7 | ||||||||
L
|
L
|
P
|
Q
|
L
|
F
|
L
|
F
|
T
|
I
|
490 |
L
|
N
|
S
|
L
|
Y
|
G
|
F
|
F
|
L
|
F
|
500 |
H8 | |||||||||
L
|
W
|
F
|
C
|
S
|
Q
|
R
|
C
|
R
|
S
|
510 |
E
|
A
|
E
|
A
|
K
|
A
|
Q
|
I
|
E
|
A
|
520 |
C-term | ||||||||
F
|
S
|
S
|
S
|
Q
|
T
|
T
|
Q
|
|
|
|||||||||
N-term | |||||||||
|
T
|
Y
|
F
|
A
|
V
|
L
|
M
|
Q
|
L
|
235 |
TM1 | |||||||||
S
|
P
|
A
|
L
|
V
|
P
|
A
|
E
|
L
|
L
|
245 |
A
|
P
|
L
|
T
|
Y
|
I
|
S
|
L
|
V
|
G
|
255 |
C
|
S
|
I
|
S
|
I
|
V
|
A
|
S
|
L
|
I
|
265 |
T
|
V
|
L
|
L
|
H
|
F
|
H
|
F
|
R
|
K
|
275 |
ICL1 | TM2 | ||||||||
Q
|
S
|
D
|
S
|
L
|
T
|
R
|
I
|
H
|
M
|
285 |
N
|
L
|
H
|
A
|
S
|
V
|
L
|
L
|
L
|
N
|
295 |
I
|
A
|
F
|
L
|
L
|
S
|
P
|
A
|
F
|
A
|
305 |
ECL1 | TM3 | ||||||||
M
|
S
|
P
|
V
|
P
|
G
|
S
|
A
|
C
|
T
|
315 |
A
|
L
|
A
|
A
|
A
|
L
|
H
|
Y
|
A
|
L
|
325 |
L
|
S
|
C
|
L
|
T
|
W
|
M
|
A
|
I
|
E
|
335 |
G
|
F
|
N
|
L
|
Y
|
L
|
L
|
L
|
G
|
R
|
345 |
ICL2 | TM4 | ||||||||
V
|
Y
|
N
|
I
|
Y
|
I
|
R
|
R
|
Y
|
V
|
355 |
F
|
K
|
L
|
G
|
V
|
L
|
G
|
W
|
G
|
A
|
365 |
P
|
A
|
L
|
L
|
V
|
L
|
L
|
S
|
L
|
S
|
375 |
ECL2 | |||||||||
V
|
K
|
S
|
S
|
V
|
Y
|
G
|
P
|
C
|
T
|
385 |
I
|
P
|
V
|
F
|
D
|
S
|
W
|
E
|
N
|
G
|
395 |
T
|
G
|
F
|
Q
|
N
|
M
|
S
|
I
|
C
|
W
|
405 |
TM5 | |||||||||
V
|
R
|
S
|
P
|
V
|
V
|
H
|
S
|
V
|
L
|
415 |
V
|
M
|
G
|
Y
|
G
|
G
|
L
|
T
|
S
|
L
|
425 |
F
|
N
|
L
|
V
|
V
|
L
|
A
|
W
|
A
|
L
|
435 |
W
|
T
|
L
|
R
|
R
|
L
|
R
|
E
|
R
|
A
|
445 |
ICL3 | TM6 | ||||||||
D
|
A
|
P
|
S
|
V
|
R
|
A
|
C
|
H
|
D
|
455 |
T
|
V
|
T
|
V
|
L
|
G
|
L
|
T
|
V
|
L
|
465 |
L
|
G
|
T
|
T
|
W
|
A
|
L
|
A
|
F
|
F
|
475 |
ECL3 | TM7 | ||||||||
S
|
F
|
G
|
V
|
F
|
L
|
L
|
P
|
Q
|
L
|
485 |
F
|
L
|
F
|
T
|
I
|
L
|
N
|
S
|
L
|
Y
|
495 |
G
|
F
|
F
|
L
|
F
|
L
|
W
|
F
|
C
|
S
|
505 |
H8 | |||||||||
Q
|
R
|
C
|
R
|
S
|
E
|
A
|
E
|
A
|
K
|
515 |
A
|
Q
|
I
|
E
|
A
|
F
|
S
|
S
|
S
|
Q
|
525 |
C-term | |||||
T
|
T
|
Q
|
|||
528 |
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
|
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|