ox2r_human
NAME
7L1U
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
ox2r_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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S
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G
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T
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K
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L
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E
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D
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S
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P
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10 |
P
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C
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R
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N
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W
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S
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S
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A
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S
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E
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20 |
L
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N
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E
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T
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Q
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E
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P
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F
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L
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N
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30 |
P
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T
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D
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Y
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D
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D
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E
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E
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F
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L
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40 |
R
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Y
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L
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W
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R
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E
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Y
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L
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H
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P
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50 |
TM1 | |||||||||
K
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E
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Y
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E
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W
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V
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L
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I
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A
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G
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60 |
Y
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I
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I
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V
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F
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V
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V
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A
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L
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I
|
70 |
G
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N
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V
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L
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V
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C
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V
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A
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V
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W
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80 |
ICL1 | TM2 | ||||||||
K
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N
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H
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H
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M
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R
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T
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V
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T
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N
|
90 |
Y
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F
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I
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V
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N
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L
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S
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L
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A
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D
|
100 |
V
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L
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V
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T
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I
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T
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C
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L
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P
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A
|
110 |
T
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L
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V
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V
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D
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I
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T
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E
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T
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W
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120 |
ECL1 | TM3 | ||||||||
F
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F
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G
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Q
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S
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L
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C
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K
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V
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I
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130 |
P
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Y
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L
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Q
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T
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V
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S
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V
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S
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V
|
140 |
S
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V
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L
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T
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L
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S
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C
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I
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A
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L
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150 |
D
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R
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W
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Y
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A
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I
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C
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H
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P
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L
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160 |
ICL2 | TM4 | ||||||||
M
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F
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K
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S
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T
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A
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K
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R
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A
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R
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170 |
N
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S
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I
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V
|
I
|
I
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W
|
I
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V
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S
|
180 |
C
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I
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I
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M
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I
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P
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Q
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A
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I
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V
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190 |
ECL2 | |||||||||
M
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E
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C
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S
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T
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V
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F
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P
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G
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L
|
200 |
A
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N
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K
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T
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T
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L
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F
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T
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V
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C
|
210 |
TM5 | |||||||||
D
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E
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R
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W
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G
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G
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E
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I
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Y
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P
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220 |
K
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M
|
Y
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H
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I
|
C
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F
|
F
|
L
|
V
|
230 |
T
|
Y
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M
|
A
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P
|
L
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C
|
L
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M
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V
|
240 |
L
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A
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Y
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L
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Q
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I
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F
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R
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K
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L
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250 |
ICL3 | |||||||||
W
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C
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R
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Q
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I
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P
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G
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T
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S
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S
|
260 |
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|
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V
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V
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Q
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R
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K
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W
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K
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P
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L
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Q
|
270 |
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|
|
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P
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V
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S
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Q
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P
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R
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G
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P
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G
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Q
|
280 |
|
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P
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T
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K
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S
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R
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M
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S
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A
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V
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A
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290 |
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|||||||||
TM6 | |||||||||
A
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E
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I
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K
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Q
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I
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R
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A
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R
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R
|
300 |
K
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T
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A
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R
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M
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L
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M
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I
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V
|
L
|
310 |
L
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V
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F
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A
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I
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C
|
Y
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L
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P
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I
|
320 |
S
|
I
|
L
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N
|
V
|
L
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K
|
R
|
V
|
F
|
330 |
ECL3 | TM7 | ||||||||
G
|
M
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F
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A
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H
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T
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E
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D
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R
|
E
|
340 |
T
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V
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Y
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A
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W
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F
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T
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F
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S
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H
|
350 |
W
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L
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V
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Y
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A
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N
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S
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A
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A
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N
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360 |
H8 | |||||||||
P
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I
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I
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Y
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N
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F
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L
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S
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G
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K
|
370 |
F
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R
|
E
|
E
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F
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K
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A
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A
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F
|
S
|
380 |
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|||||||||
C-term | |||||||||
C
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C
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C
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L
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G
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V
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H
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H
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R
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Q
|
390 |
|
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|
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E
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D
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R
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L
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T
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R
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G
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R
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T
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S
|
400 |
|
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|
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T
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E
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S
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R
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K
|
S
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L
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T
|
T
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Q
|
410 |
|
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|
|
|
|
|
|
|
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I
|
S
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N
|
F
|
D
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N
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I
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S
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K
|
L
|
420 |
|
|
|
|
|
|
|
|
|
|
S
|
E
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Q
|
V
|
V
|
L
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T
|
S
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I
|
S
|
430 |
|
|
|
|
|
|
|
|
|
|
T
|
L
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P
|
A
|
A
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N
|
G
|
A
|
G
|
P
|
440 |
|
|
|
|
L
|
Q
|
N
|
W
|
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|||||||||
N-term | |||||||||
|
G
|
T
|
K
|
L
|
E
|
D
|
S
|
P
|
P
|
11 |
C
|
R
|
N
|
W
|
S
|
S
|
A
|
S
|
E
|
L
|
21 |
N
|
E
|
T
|
Q
|
E
|
P
|
F
|
L
|
N
|
P
|
31 |
T
|
D
|
Y
|
D
|
D
|
E
|
E
|
F
|
L
|
R
|
41 |
Y
|
L
|
W
|
R
|
E
|
Y
|
L
|
H
|
P
|
K
|
51 |
TM1 | |||||||||
E
|
Y
|
E
|
W
|
V
|
L
|
I
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A
|
G
|
Y
|
61 |
I
|
I
|
V
|
F
|
V
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V
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A
|
L
|
I
|
G
|
71 |
N
|
V
|
L
|
V
|
C
|
V
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A
|
V
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W
|
K
|
81 |
ICL1 | TM2 | ||||||||
N
|
H
|
H
|
M
|
R
|
T
|
V
|
T
|
N
|
Y
|
91 |
F
|
I
|
V
|
N
|
L
|
S
|
L
|
A
|
D
|
V
|
101 |
L
|
V
|
T
|
I
|
T
|
C
|
L
|
P
|
A
|
T
|
111 |
L
|
V
|
V
|
D
|
I
|
T
|
E
|
T
|
W
|
F
|
121 |
ECL1 | TM3 | ||||||||
F
|
G
|
Q
|
S
|
L
|
C
|
K
|
V
|
I
|
P
|
131 |
Y
|
L
|
Q
|
T
|
V
|
S
|
V
|
S
|
V
|
S
|
141 |
V
|
L
|
T
|
L
|
S
|
C
|
I
|
A
|
L
|
D
|
151 |
R
|
W
|
Y
|
A
|
I
|
C
|
H
|
P
|
L
|
M
|
161 |
ICL2 | TM4 | ||||||||
F
|
K
|
S
|
T
|
A
|
K
|
R
|
A
|
R
|
N
|
171 |
S
|
I
|
V
|
I
|
I
|
W
|
I
|
V
|
S
|
C
|
181 |
I
|
I
|
M
|
I
|
P
|
Q
|
A
|
I
|
V
|
M
|
191 |
ECL2 | |||||||||
E
|
C
|
S
|
T
|
V
|
F
|
P
|
G
|
L
|
A
|
201 |
N
|
K
|
T
|
T
|
L
|
F
|
T
|
V
|
C
|
D
|
211 |
TM5 | |||||||||
E
|
R
|
W
|
G
|
G
|
E
|
I
|
Y
|
P
|
K
|
221 |
M
|
Y
|
H
|
I
|
C
|
F
|
F
|
L
|
V
|
T
|
231 |
Y
|
M
|
A
|
P
|
L
|
C
|
L
|
M
|
V
|
L
|
241 |
A
|
Y
|
L
|
Q
|
I
|
F
|
R
|
K
|
L
|
W
|
251 |
|
|||||||||
ICL3 | |||||||||
C
|
R
|
Q
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I
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P
|
G
|
T
|
S
|
S
|
|
TM6 | |||||||||
E
|
I
|
K
|
Q
|
I
|
R
|
A
|
R
|
R
|
K
|
301 |
T
|
A
|
R
|
M
|
L
|
M
|
I
|
V
|
L
|
L
|
311 |
V
|
F
|
A
|
I
|
C
|
Y
|
L
|
P
|
I
|
S
|
321 |
I
|
L
|
N
|
V
|
L
|
K
|
R
|
V
|
F
|
G
|
331 |
ECL3 | TM7 | ||||||||
M
|
F
|
A
|
H
|
T
|
E
|
D
|
R
|
E
|
T
|
341 |
V
|
Y
|
A
|
W
|
F
|
T
|
F
|
S
|
H
|
W
|
351 |
L
|
V
|
Y
|
A
|
N
|
S
|
A
|
A
|
N
|
P
|
361 |
H8 | |||||||||
I
|
I
|
Y
|
N
|
F
|
L
|
S
|
G
|
K
|
F
|
371 |
R
|
E
|
E
|
F
|
K
|
A
|
A
|
F
|
S
|
C
|
381 |
|
||||||||
C-term | ||||||||
C
|
C
|
L
|
G
|
V
|
H
|
H
|
R
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
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Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|