oprm_mouse
NAME
7SBF
ORGANISM
Mouse (Mus musculus)
PROTEIN NAME
oprm_mouse
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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D
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S
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S
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A
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G
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P
|
G
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N
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I
|
10 |
|
|
|
|
|
|
|
|
|
|
S
|
D
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C
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S
|
D
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P
|
L
|
A
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P
|
A
|
20 |
|
|
|
|
|
|
|
|
|
|
S
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C
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S
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P
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A
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P
|
G
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S
|
W
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L
|
30 |
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|
|
|
|
|
|
|
|
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N
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L
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S
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H
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V
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D
|
G
|
N
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Q
|
S
|
40 |
|
|
|
|
|
|
|
|
|
|
D
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P
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C
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G
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P
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N
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R
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T
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G
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L
|
50 |
|
|
|
|
|
|
|
|
|
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G
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G
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S
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H
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S
|
L
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C
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P
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Q
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T
|
60 |
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|
|
|
|
|
|
|
|
TM1 | |||||||||
G
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S
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P
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S
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M
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V
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T
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A
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I
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T
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70 |
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||||||||
I
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M
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A
|
L
|
Y
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S
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I
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V
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C
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V
|
80 |
V
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G
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L
|
F
|
G
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N
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F
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L
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V
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M
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90 |
ICL1 | |||||||||
Y
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V
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I
|
V
|
R
|
Y
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T
|
K
|
M
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K
|
100 |
TM2 | |||||||||
T
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A
|
T
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N
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I
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Y
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I
|
F
|
N
|
L
|
110 |
A
|
L
|
A
|
D
|
A
|
L
|
A
|
T
|
S
|
T
|
120 |
L
|
P
|
F
|
Q
|
S
|
V
|
N
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Y
|
L
|
M
|
130 |
ECL1 | TM3 | ||||||||
G
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T
|
W
|
P
|
F
|
G
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N
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I
|
L
|
C
|
140 |
K
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I
|
V
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I
|
S
|
I
|
D
|
Y
|
Y
|
N
|
150 |
M
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F
|
T
|
S
|
I
|
F
|
T
|
L
|
C
|
T
|
160 |
M
|
S
|
V
|
D
|
R
|
Y
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I
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A
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V
|
C
|
170 |
ICL2 | |||||||||
H
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P
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V
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K
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A
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L
|
D
|
F
|
R
|
T
|
180 |
TM4 | |||||||||
P
|
R
|
N
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A
|
K
|
I
|
V
|
N
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V
|
C
|
190 |
N
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W
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I
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L
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S
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S
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A
|
I
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G
|
L
|
200 |
ECL2 | |||||||||
P
|
V
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M
|
F
|
M
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A
|
T
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T
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K
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Y
|
210 |
R
|
Q
|
G
|
S
|
I
|
D
|
C
|
T
|
L
|
T
|
220 |
TM5 | |||||||||
F
|
S
|
H
|
P
|
T
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W
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Y
|
W
|
E
|
N
|
230 |
L
|
L
|
K
|
I
|
C
|
V
|
F
|
I
|
F
|
A
|
240 |
F
|
I
|
M
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P
|
V
|
L
|
I
|
I
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T
|
V
|
250 |
C
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Y
|
G
|
L
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M
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I
|
L
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R
|
L
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K
|
260 |
ICL3 | TM6 | ||||||||
S
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V
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R
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M
|
L
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S
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G
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S
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K
|
E
|
270 |
K
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D
|
R
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N
|
L
|
R
|
R
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I
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T
|
R
|
280 |
M
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V
|
L
|
V
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V
|
V
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A
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V
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F
|
I
|
290 |
V
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C
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W
|
T
|
P
|
I
|
H
|
I
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Y
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V
|
300 |
ECL3 | |||||||||
I
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I
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K
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A
|
L
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I
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T
|
I
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P
|
E
|
310 |
TM7 | |||||||||
T
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T
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F
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Q
|
T
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V
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S
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W
|
H
|
F
|
320 |
C
|
I
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A
|
L
|
G
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Y
|
T
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N
|
S
|
C
|
330 |
L
|
N
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P
|
V
|
L
|
Y
|
A
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F
|
L
|
D
|
340 |
H8 | |||||||||
E
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N
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F
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K
|
R
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C
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F
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R
|
E
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F
|
350 |
C-term | |||||||||
C
|
I
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P
|
T
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S
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S
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T
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I
|
E
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Q
|
360 |
Q
|
N
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S
|
A
|
R
|
I
|
R
|
Q
|
N
|
T
|
370 |
R
|
E
|
H
|
P
|
S
|
T
|
A
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N
|
T
|
V
|
380 |
D
|
R
|
T
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N
|
H
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Q
|
L
|
E
|
N
|
L
|
390 |
E
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A
|
E
|
T
|
A
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P
|
L
|
P
|
|
|||||||||
TM1 | |||||||||
|
A
|
L
|
Y
|
S
|
I
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V
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C
|
V
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V
|
81 |
G
|
L
|
F
|
G
|
N
|
F
|
L
|
V
|
M
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Y
|
91 |
ICL1 | |||||||||
V
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I
|
V
|
R
|
Y
|
T
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K
|
M
|
K
|
T
|
101 |
TM2 | |||||||||
A
|
T
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N
|
I
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Y
|
I
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F
|
N
|
L
|
A
|
111 |
L
|
A
|
D
|
A
|
L
|
A
|
T
|
S
|
T
|
L
|
121 |
P
|
F
|
Q
|
S
|
V
|
N
|
Y
|
L
|
M
|
G
|
131 |
ECL1 | TM3 | ||||||||
T
|
W
|
P
|
F
|
G
|
N
|
I
|
L
|
C
|
K
|
141 |
I
|
V
|
I
|
S
|
I
|
D
|
Y
|
Y
|
N
|
M
|
151 |
F
|
T
|
S
|
I
|
F
|
T
|
L
|
C
|
T
|
M
|
161 |
S
|
V
|
D
|
R
|
Y
|
I
|
A
|
V
|
C
|
H
|
171 |
ICL2 | |||||||||
P
|
V
|
K
|
A
|
L
|
D
|
F
|
R
|
T
|
P
|
181 |
TM4 | |||||||||
R
|
N
|
A
|
K
|
I
|
V
|
N
|
V
|
C
|
N
|
191 |
W
|
I
|
L
|
S
|
S
|
A
|
I
|
G
|
L
|
P
|
201 |
ECL2 | |||||||||
V
|
M
|
F
|
M
|
A
|
T
|
T
|
K
|
Y
|
R
|
211 |
Q
|
G
|
S
|
I
|
D
|
C
|
T
|
L
|
T
|
F
|
221 |
TM5 | |||||||||
S
|
H
|
P
|
T
|
W
|
Y
|
W
|
E
|
N
|
L
|
231 |
L
|
K
|
I
|
C
|
V
|
F
|
I
|
F
|
A
|
F
|
241 |
I
|
M
|
P
|
V
|
L
|
I
|
I
|
T
|
V
|
C
|
251 |
Y
|
G
|
L
|
M
|
I
|
L
|
R
|
L
|
K
|
S
|
261 |
ICL3 | TM6 | ||||||||
V
|
R
|
M
|
L
|
S
|
G
|
S
|
K
|
E
|
K
|
271 |
D
|
R
|
N
|
L
|
R
|
R
|
I
|
T
|
R
|
M
|
281 |
V
|
L
|
V
|
V
|
V
|
A
|
V
|
F
|
I
|
V
|
291 |
C
|
W
|
T
|
P
|
I
|
H
|
I
|
Y
|
V
|
I
|
301 |
ECL3 | |||||||||
I
|
K
|
A
|
L
|
I
|
T
|
I
|
P
|
E
|
T
|
311 |
TM7 | |||||||||
T
|
F
|
Q
|
T
|
V
|
S
|
W
|
H
|
F
|
C
|
321 |
I
|
A
|
L
|
G
|
Y
|
T
|
N
|
S
|
C
|
L
|
331 |
H8 | |||||||||
N
|
P
|
V
|
L
|
Y
|
A
|
F
|
L
|
D
|
E
|
341 |
N
|
F
|
K
|
R
|
C
|
F
|
R
|
E
|
F
|
C
|
351 |
C-term | |||||||||
I
|
P
|
T
|
S
|
S
|
T
|
I
|
E
|
Q
|
Q
|
361 |
N
|
S
|
A
|
R
|
I
|
R
|
Q
|
N
|
T
|
R
|
371 |
E
|
H
|
P
|
S
|
T
|
A
|
N
|
T
|
V
|
D
|
381 |
R
|
T
|
N
|
H
|
Q
|
L
|
E
|
N
|
L
|
E
|
391 |
A
|
E
|
T
|
A
|
P
|
L
|
P
|
398 |
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
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DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|