glp1r_human
NAME
7X8R
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
glp1r_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
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N-term | |||||||||
M
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A
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G
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A
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P
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G
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P
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L
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R
|
L
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10 |
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|
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|
|
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A
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L
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L
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L
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L
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G
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M
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V
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G
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R
|
20 |
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|
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|||||||
A
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G
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P
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R
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P
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Q
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G
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A
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T
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V
|
30 |
S
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L
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W
|
E
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T
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V
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Q
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K
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W
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R
|
40 |
E
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Y
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R
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R
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Q
|
C
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Q
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R
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S
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L
|
50 |
T
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E
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D
|
P
|
P
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P
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A
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T
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D
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L
|
60 |
F
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C
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N
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R
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T
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F
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D
|
E
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Y
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A
|
70 |
C
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W
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P
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D
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G
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E
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P
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G
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S
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F
|
80 |
V
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N
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V
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S
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C
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P
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W
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Y
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L
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P
|
90 |
W
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A
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S
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S
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V
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P
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Q
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G
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H
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V
|
100 |
Y
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R
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F
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C
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T
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A
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E
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G
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L
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W
|
110 |
L
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Q
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K
|
D
|
N
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S
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S
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L
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P
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W
|
120 |
R
|
D
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L
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S
|
E
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C
|
E
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E
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S
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K
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130 |
TM1 | |||||||||
R
|
G
|
E
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R
|
S
|
S
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P
|
E
|
E
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Q
|
140 |
L
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L
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F
|
L
|
Y
|
I
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I
|
Y
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T
|
V
|
150 |
G
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Y
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A
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L
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S
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F
|
S
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A
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L
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V
|
160 |
I
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A
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S
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A
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I
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L
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L
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G
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F
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R
|
170 |
ICL1 | TM2 | ||||||||
H
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L
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H
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C
|
T
|
R
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N
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Y
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I
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H
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180 |
L
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N
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L
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F
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A
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S
|
F
|
I
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L
|
R
|
190 |
A
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L
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S
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V
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F
|
I
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K
|
D
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A
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A
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200 |
ECL1 | |||||||||
L
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K
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W
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M
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Y
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S
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T
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A
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A
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Q
|
210 |
Q
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H
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Q
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W
|
D
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G
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L
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L
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S
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Y
|
220 |
TM3 | |||||||||
Q
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D
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S
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L
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S
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C
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R
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L
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V
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F
|
230 |
L
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L
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M
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Q
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Y
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C
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V
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A
|
A
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N
|
240 |
Y
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Y
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W
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L
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L
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V
|
E
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G
|
V
|
Y
|
250 |
L
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Y
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T
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L
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L
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A
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F
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S
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V
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L
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260 |
TM4 | |||||||||
S
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E
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Q
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W
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I
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F
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R
|
L
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Y
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V
|
270 |
S
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I
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G
|
W
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G
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V
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P
|
L
|
L
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F
|
280 |
V
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V
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P
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W
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G
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I
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V
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K
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Y
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L
|
290 |
ECL2 | |||||||||
Y
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E
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D
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E
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G
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C
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W
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T
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R
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N
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300 |
TM5 | |||||||||
S
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N
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M
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N
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Y
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W
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L
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I
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I
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R
|
310 |
L
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P
|
I
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L
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F
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A
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I
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G
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V
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N
|
320 |
F
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L
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I
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F
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V
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R
|
V
|
I
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C
|
I
|
330 |
V
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V
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S
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K
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L
|
K
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A
|
N
|
L
|
M
|
340 |
TM6 | |||||||||
C
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K
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T
|
D
|
I
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K
|
C
|
R
|
L
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A
|
350 |
K
|
S
|
T
|
L
|
T
|
L
|
I
|
P
|
L
|
L
|
360 |
G
|
T
|
H
|
E
|
V
|
I
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F
|
A
|
F
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V
|
370 |
ECL3 | TM7 | ||||||||
M
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D
|
E
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H
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A
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R
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G
|
T
|
L
|
R
|
380 |
F
|
I
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K
|
L
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F
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T
|
E
|
L
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S
|
F
|
390 |
T
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S
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F
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Q
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G
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L
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M
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V
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A
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I
|
400 |
H8 | |||||||||
L
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Y
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C
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F
|
V
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N
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N
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E
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V
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Q
|
410 |
L
|
E
|
F
|
R
|
K
|
S
|
W
|
E
|
R
|
W
|
420 |
R
|
L
|
E
|
H
|
L
|
H
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I
|
Q
|
R
|
D
|
430 |
C-term | |||||||||
S
|
S
|
M
|
K
|
P
|
L
|
K
|
C
|
P
|
T
|
440 |
S
|
S
|
L
|
S
|
S
|
G
|
A
|
T
|
A
|
G
|
450 |
S
|
S
|
M
|
Y
|
T
|
A
|
T
|
C
|
Q
|
A
|
460 |
S
|
C
|
S
|
|
|||||||||
N-term | |||||||||
|
R
|
P
|
Q
|
G
|
A
|
T
|
V
|
S
|
L
|
32 |
W
|
E
|
T
|
V
|
Q
|
K
|
W
|
R
|
E
|
Y
|
42 |
R
|
R
|
Q
|
C
|
Q
|
R
|
S
|
L
|
T
|
E
|
52 |
D
|
P
|
P
|
P
|
A
|
T
|
D
|
L
|
F
|
C
|
62 |
N
|
R
|
T
|
F
|
D
|
E
|
Y
|
A
|
C
|
W
|
72 |
P
|
D
|
G
|
E
|
P
|
G
|
S
|
F
|
V
|
N
|
82 |
V
|
S
|
C
|
P
|
W
|
Y
|
L
|
P
|
W
|
A
|
92 |
S
|
S
|
V
|
P
|
Q
|
G
|
H
|
V
|
Y
|
R
|
102 |
F
|
C
|
T
|
A
|
E
|
G
|
L
|
W
|
L
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Q
|
112 |
K
|
D
|
N
|
S
|
S
|
L
|
P
|
W
|
R
|
D
|
122 |
L
|
S
|
E
|
C
|
E
|
E
|
S
|
K
|
R
|
G
|
132 |
TM1 | |||||||||
E
|
R
|
S
|
S
|
P
|
E
|
E
|
Q
|
L
|
L
|
142 |
F
|
L
|
Y
|
I
|
I
|
Y
|
T
|
V
|
G
|
Y
|
152 |
A
|
L
|
S
|
F
|
S
|
A
|
L
|
V
|
I
|
A
|
162 |
S
|
A
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I
|
L
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L
|
G
|
F
|
R
|
H
|
L
|
172 |
ICL1 | TM2 | ||||||||
H
|
C
|
T
|
R
|
N
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Y
|
I
|
H
|
L
|
N
|
182 |
L
|
F
|
A
|
S
|
F
|
I
|
L
|
R
|
A
|
L
|
192 |
S
|
V
|
F
|
I
|
K
|
D
|
A
|
A
|
L
|
K
|
202 |
ECL1 | |||||||||
W
|
M
|
Y
|
S
|
T
|
A
|
A
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Q
|
Q
|
H
|
212 |
Q
|
W
|
D
|
G
|
L
|
L
|
S
|
Y
|
Q
|
D
|
222 |
TM3 | |||||||||
S
|
L
|
S
|
C
|
R
|
L
|
V
|
F
|
L
|
L
|
232 |
M
|
Q
|
Y
|
C
|
V
|
A
|
A
|
N
|
Y
|
Y
|
242 |
W
|
L
|
L
|
V
|
E
|
G
|
V
|
Y
|
L
|
Y
|
252 |
ICL2 | |||||||||
T
|
L
|
L
|
A
|
F
|
S
|
V
|
L
|
S
|
E
|
262 |
TM4 | |||||||||
Q
|
W
|
I
|
F
|
R
|
L
|
Y
|
V
|
S
|
I
|
272 |
G
|
W
|
G
|
V
|
P
|
L
|
L
|
F
|
V
|
V
|
282 |
P
|
W
|
G
|
I
|
V
|
K
|
Y
|
L
|
Y
|
E
|
292 |
ECL2 | |||||||||
D
|
E
|
G
|
C
|
W
|
T
|
R
|
N
|
S
|
N
|
302 |
TM5 | |||||||||
M
|
N
|
Y
|
W
|
L
|
I
|
I
|
R
|
L
|
P
|
312 |
I
|
L
|
F
|
A
|
I
|
G
|
V
|
N
|
F
|
L
|
322 |
I
|
F
|
V
|
R
|
V
|
I
|
C
|
I
|
V
|
V
|
332 |
S
|
K
|
L
|
K
|
A
|
N
|
L
|
M
|
C
|
K
|
342 |
TM6 | |||||||||
T
|
D
|
I
|
K
|
C
|
R
|
L
|
A
|
K
|
S
|
352 |
T
|
L
|
T
|
L
|
I
|
P
|
L
|
L
|
G
|
T
|
362 |
H
|
E
|
V
|
I
|
F
|
A
|
F
|
V
|
M
|
D
|
372 |
ECL3 | TM7 | ||||||||
E
|
H
|
A
|
R
|
G
|
T
|
L
|
R
|
F
|
I
|
382 |
K
|
L
|
F
|
T
|
E
|
L
|
S
|
F
|
T
|
S
|
392 |
F
|
Q
|
G
|
L
|
M
|
V
|
A
|
I
|
L
|
Y
|
402 |
H8 | |||||||||
C
|
F
|
V
|
N
|
N
|
E
|
V
|
Q
|
L
|
E
|
412 |
F
|
R
|
K
|
S
|
W
|
E
|
R
|
W
|
R
|
L
|
422 |
E
|
H
|
L
|
H
|
I
|
Q
|
R
|
D
|
S
|
S
|
432 |
C-term | |||||||||
M
|
K
|
P
|
L
|
K
|
C
|
P
|
T
|
S
|
S
|
442 |
L
|
S
|
S
|
G
|
A
|
T
|
A
|
G
|
S
|
S
|
452 |
M
|
Y
|
T
|
A
|
T
|
C
|
Q
|
A
|
S
|
C
|
462 |
S
|
463 |
SCHEMATIC
Perspective:
Wild-type
Construct
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DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|