ssr2_human
NAME
7YAC
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
ssr2_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
|
|
|
|
|
|
|
|
|
|
N-term | |||||||||
M
|
D
|
M
|
A
|
D
|
E
|
P
|
L
|
N
|
G
|
10 |
|
|
|
|
|
|
|
|
|
|
S
|
H
|
T
|
W
|
L
|
S
|
I
|
P
|
F
|
D
|
20 |
|
|
|
|
|
|
|
|
|
|
L
|
N
|
G
|
S
|
V
|
V
|
S
|
T
|
N
|
T
|
30 |
S
|
N
|
Q
|
T
|
E
|
P
|
Y
|
Y
|
D
|
L
|
40 |
TM1 | |||||||||
T
|
S
|
N
|
A
|
V
|
L
|
T
|
F
|
I
|
Y
|
50 |
F
|
V
|
V
|
C
|
I
|
I
|
G
|
L
|
C
|
G
|
60 |
N
|
T
|
L
|
V
|
I
|
Y
|
V
|
I
|
L
|
R
|
70 |
ICL1 | TM2 | ||||||||
Y
|
A
|
K
|
M
|
K
|
T
|
I
|
T
|
N
|
I
|
80 |
Y
|
I
|
L
|
N
|
L
|
A
|
I
|
A
|
D
|
E
|
90 |
L
|
F
|
M
|
L
|
G
|
L
|
P
|
F
|
L
|
A
|
100 |
ECL1 | |||||||||
M
|
Q
|
V
|
A
|
L
|
V
|
H
|
W
|
P
|
F
|
110 |
TM3 | |||||||||
G
|
K
|
A
|
I
|
C
|
R
|
V
|
V
|
M
|
T
|
120 |
V
|
D
|
G
|
I
|
N
|
Q
|
F
|
T
|
S
|
I
|
130 |
F
|
C
|
L
|
T
|
V
|
M
|
S
|
I
|
D
|
R
|
140 |
ICL2 | |||||||||
Y
|
L
|
A
|
V
|
V
|
H
|
P
|
I
|
K
|
S
|
150 |
TM4 | |||||||||
A
|
K
|
W
|
R
|
R
|
P
|
R
|
T
|
A
|
K
|
160 |
M
|
I
|
T
|
M
|
A
|
V
|
W
|
G
|
V
|
S
|
170 |
L
|
L
|
V
|
I
|
L
|
P
|
I
|
M
|
I
|
Y
|
180 |
ECL2 | |||||||||
A
|
G
|
L
|
R
|
S
|
N
|
Q
|
W
|
G
|
R
|
190 |
S
|
S
|
C
|
T
|
I
|
N
|
W
|
P
|
G
|
E
|
200 |
TM5 | |||||||||
S
|
G
|
A
|
W
|
Y
|
T
|
G
|
F
|
I
|
I
|
210 |
Y
|
T
|
F
|
I
|
L
|
G
|
F
|
L
|
V
|
P
|
220 |
L
|
T
|
I
|
I
|
C
|
L
|
C
|
Y
|
L
|
F
|
230 |
I
|
I
|
I
|
K
|
V
|
K
|
S
|
S
|
G
|
I
|
240 |
ICL3 | TM6 | ||||||||
R
|
V
|
G
|
S
|
S
|
K
|
R
|
K
|
K
|
S
|
250 |
E
|
K
|
K
|
V
|
T
|
R
|
M
|
V
|
S
|
I
|
260 |
V
|
V
|
A
|
V
|
F
|
I
|
F
|
C
|
W
|
L
|
270 |
P
|
F
|
Y
|
I
|
F
|
N
|
V
|
S
|
S
|
V
|
280 |
ECL3 | TM7 | ||||||||
S
|
M
|
A
|
I
|
S
|
P
|
T
|
P
|
A
|
L
|
290 |
K
|
G
|
M
|
F
|
D
|
F
|
V
|
V
|
V
|
L
|
300 |
T
|
Y
|
A
|
N
|
S
|
C
|
A
|
N
|
P
|
I
|
310 |
H8 | |||||||||
L
|
Y
|
A
|
F
|
L
|
S
|
D
|
N
|
F
|
K
|
320 |
K
|
S
|
F
|
Q
|
N
|
V
|
L
|
C
|
L
|
V
|
330 |
|
|
||||||||
C-term | |||||||||
K
|
V
|
S
|
G
|
T
|
D
|
D
|
G
|
E
|
R
|
340 |
|
|
|
|
|
|
|
|
|
|
S
|
D
|
S
|
K
|
Q
|
D
|
K
|
S
|
R
|
L
|
350 |
|
|
|
|
|
|
|
|
|
|
N
|
E
|
T
|
T
|
E
|
T
|
Q
|
R
|
T
|
L
|
360 |
|
|
|
|
|
|
|
|
|
L
|
N
|
G
|
D
|
L
|
Q
|
T
|
S
|
I
|
|
|||||||||
N-term | |||||||||
|
S
|
N
|
Q
|
T
|
E
|
P
|
Y
|
Y
|
D
|
39 |
TM1 | |||||||||
L
|
T
|
S
|
N
|
A
|
V
|
L
|
T
|
F
|
I
|
49 |
Y
|
F
|
V
|
V
|
C
|
I
|
I
|
G
|
L
|
C
|
59 |
G
|
N
|
T
|
L
|
V
|
I
|
Y
|
V
|
I
|
L
|
69 |
ICL1 | TM2 | ||||||||
R
|
Y
|
A
|
K
|
M
|
K
|
T
|
I
|
T
|
N
|
79 |
I
|
Y
|
I
|
L
|
N
|
L
|
A
|
I
|
A
|
D
|
89 |
E
|
L
|
F
|
M
|
L
|
G
|
L
|
P
|
F
|
L
|
99 |
ECL1 | |||||||||
A
|
M
|
Q
|
V
|
A
|
L
|
V
|
H
|
W
|
P
|
109 |
TM3 | |||||||||
F
|
G
|
K
|
A
|
I
|
C
|
R
|
V
|
V
|
M
|
119 |
T
|
V
|
D
|
G
|
I
|
N
|
Q
|
F
|
T
|
S
|
129 |
I
|
F
|
C
|
L
|
T
|
V
|
M
|
S
|
I
|
D
|
139 |
R
|
Y
|
L
|
A
|
V
|
V
|
H
|
P
|
I
|
K
|
149 |
ICL2 | TM4 | ||||||||
S
|
A
|
K
|
W
|
R
|
R
|
P
|
R
|
T
|
A
|
159 |
K
|
M
|
I
|
T
|
M
|
A
|
V
|
W
|
G
|
V
|
169 |
S
|
L
|
L
|
V
|
I
|
L
|
P
|
I
|
M
|
I
|
179 |
ECL2 | |||||||||
Y
|
A
|
G
|
L
|
R
|
S
|
N
|
Q
|
W
|
G
|
189 |
R
|
S
|
S
|
C
|
T
|
I
|
N
|
W
|
P
|
G
|
199 |
TM5 | |||||||||
E
|
S
|
G
|
A
|
W
|
Y
|
T
|
G
|
F
|
I
|
209 |
I
|
Y
|
T
|
F
|
I
|
L
|
G
|
F
|
L
|
V
|
219 |
P
|
L
|
T
|
I
|
I
|
C
|
L
|
C
|
Y
|
L
|
229 |
F
|
I
|
I
|
I
|
K
|
V
|
K
|
S
|
S
|
G
|
239 |
ICL3 | TM6 | ||||||||
I
|
R
|
V
|
G
|
S
|
S
|
K
|
R
|
K
|
K
|
249 |
S
|
E
|
K
|
K
|
V
|
T
|
R
|
M
|
V
|
S
|
259 |
I
|
V
|
V
|
A
|
V
|
F
|
I
|
F
|
C
|
W
|
269 |
L
|
P
|
F
|
Y
|
I
|
F
|
N
|
V
|
S
|
S
|
279 |
ECL3 | TM7 | ||||||||
V
|
S
|
M
|
A
|
I
|
S
|
P
|
T
|
P
|
A
|
289 |
L
|
K
|
G
|
M
|
F
|
D
|
F
|
V
|
V
|
V
|
299 |
L
|
T
|
Y
|
A
|
N
|
S
|
C
|
A
|
N
|
P
|
309 |
H8 | |||||||||
I
|
L
|
Y
|
A
|
F
|
L
|
S
|
D
|
N
|
F
|
319 |
K
|
K
|
S
|
F
|
Q
|
N
|
V
|
L
|
C
|
L
|
329 |
|
|||||||||
C-term | |||||||||
V
|
K
|
V
|
S
|
G
|
T
|
D
|
D
|
G
|
|
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|