gpr20_human
NAME
8HSC
ORGANISM
Human (Homo sapiens)
PROTEIN NAME
gpr20_human
SOURCE
SWISSPROT
SEQUENCE
Perspective:
Wild-type
Construct
N-term | |||||||||
M
|
P
|
S
|
V
|
S
|
P
|
A
|
G
|
P
|
S
|
10 |
A
|
G
|
A
|
V
|
P
|
N
|
A
|
T
|
A
|
V
|
20 |
T
|
T
|
V
|
R
|
T
|
N
|
A
|
S
|
G
|
L
|
30 |
E
|
V
|
P
|
L
|
F
|
H
|
L
|
F
|
A
|
R
|
40 |
L
|
D
|
E
|
E
|
L
|
H
|
G
|
T
|
F
|
P
|
50 |
TM1 | |||||||||
G
|
L
|
W
|
L
|
A
|
L
|
M
|
A
|
V
|
H
|
60 |
G
|
A
|
I
|
F
|
L
|
A
|
G
|
L
|
V
|
L
|
70 |
N
|
G
|
L
|
A
|
L
|
Y
|
V
|
F
|
C
|
C
|
80 |
ICL1 | TM2 | ||||||||
R
|
T
|
R
|
A
|
K
|
T
|
P
|
S
|
V
|
I
|
90 |
Y
|
T
|
I
|
N
|
L
|
V
|
V
|
T
|
D
|
L
|
100 |
L
|
V
|
G
|
L
|
S
|
L
|
P
|
T
|
R
|
F
|
110 |
A
|
V
|
Y
|
Y
|
G
|
A
|
R
|
G
|
C
|
L
|
120 |
ECL1 | TM3 | ||||||||
R
|
C
|
A
|
F
|
P
|
H
|
V
|
L
|
G
|
Y
|
130 |
F
|
L
|
N
|
M
|
H
|
C
|
S
|
I
|
L
|
F
|
140 |
L
|
T
|
C
|
I
|
C
|
V
|
D
|
R
|
Y
|
L
|
150 |
ICL2 | |||||||||
A
|
I
|
V
|
R
|
P
|
E
|
G
|
S
|
R
|
R
|
160 |
TM4 | |||||||||
C
|
R
|
Q
|
P
|
A
|
C
|
A
|
R
|
A
|
V
|
170 |
C
|
A
|
F
|
V
|
W
|
L
|
A
|
A
|
G
|
A
|
180 |
V
|
T
|
L
|
S
|
V
|
L
|
G
|
V
|
T
|
G
|
190 |
ECL2 | TM5 | ||||||||
S
|
R
|
P
|
C
|
C
|
R
|
V
|
F
|
A
|
L
|
200 |
T
|
V
|
L
|
E
|
F
|
L
|
L
|
P
|
L
|
L
|
210 |
V
|
I
|
S
|
V
|
F
|
T
|
G
|
R
|
I
|
M
|
220 |
ICL3 | |||||||||
C
|
A
|
L
|
S
|
R
|
P
|
G
|
L
|
L
|
H
|
230 |
TM6 | |||||||||
Q
|
G
|
R
|
Q
|
R
|
R
|
V
|
R
|
A
|
M
|
240 |
Q
|
L
|
L
|
L
|
T
|
V
|
L
|
I
|
I
|
F
|
250 |
L
|
V
|
C
|
F
|
T
|
P
|
F
|
H
|
A
|
R
|
260 |
Q
|
V
|
A
|
V
|
A
|
L
|
W
|
P
|
D
|
M
|
270 |
TM7 | |||||||||
P
|
H
|
H
|
T
|
S
|
L
|
V
|
V
|
Y
|
H
|
280 |
V
|
A
|
V
|
T
|
L
|
S
|
S
|
L
|
N
|
S
|
290 |
C
|
M
|
D
|
P
|
I
|
V
|
Y
|
C
|
F
|
V
|
300 |
H8 | |||||||||
T
|
S
|
G
|
F
|
Q
|
A
|
T
|
V
|
R
|
G
|
310 |
L
|
F
|
G
|
Q
|
H
|
G
|
E
|
R
|
E
|
P
|
320 |
C-term | |||||||||
S
|
S
|
G
|
D
|
V
|
V
|
S
|
M
|
H
|
R
|
330 |
S
|
S
|
K
|
G
|
S
|
G
|
R
|
H
|
H
|
I
|
340 |
L
|
S
|
A
|
G
|
P
|
H
|
A
|
L
|
T
|
Q
|
350 |
A
|
L
|
A
|
N
|
G
|
P
|
E
|
A
|
N-term | |||||||||
M
|
P
|
S
|
V
|
S
|
P
|
A
|
G
|
P
|
S
|
10 |
A
|
G
|
A
|
V
|
P
|
N
|
A
|
T
|
A
|
V
|
20 |
T
|
T
|
V
|
R
|
T
|
N
|
A
|
S
|
G
|
L
|
30 |
E
|
V
|
P
|
L
|
F
|
H
|
L
|
F
|
A
|
R
|
40 |
L
|
D
|
E
|
E
|
L
|
H
|
G
|
T
|
F
|
P
|
50 |
TM1 | |||||||||
G
|
L
|
W
|
L
|
A
|
L
|
M
|
A
|
V
|
H
|
60 |
G
|
A
|
I
|
F
|
L
|
A
|
G
|
L
|
V
|
L
|
70 |
N
|
G
|
L
|
A
|
L
|
Y
|
V
|
F
|
C
|
C
|
80 |
ICL1 | TM2 | ||||||||
R
|
T
|
R
|
A
|
K
|
T
|
P
|
S
|
V
|
I
|
90 |
Y
|
T
|
I
|
N
|
L
|
V
|
V
|
T
|
D
|
L
|
100 |
L
|
V
|
G
|
L
|
S
|
L
|
P
|
T
|
R
|
F
|
110 |
A
|
V
|
Y
|
Y
|
G
|
A
|
R
|
G
|
C
|
L
|
120 |
ECL1 | TM3 | ||||||||
R
|
C
|
A
|
F
|
P
|
H
|
V
|
L
|
G
|
Y
|
130 |
F
|
L
|
N
|
M
|
H
|
C
|
S
|
I
|
L
|
F
|
140 |
L
|
T
|
C
|
I
|
C
|
V
|
D
|
R
|
Y
|
L
|
150 |
ICL2 | |||||||||
A
|
I
|
V
|
R
|
P
|
E
|
G
|
S
|
R
|
R
|
160 |
TM4 | |||||||||
C
|
R
|
Q
|
P
|
A
|
C
|
A
|
R
|
A
|
V
|
170 |
C
|
A
|
F
|
V
|
W
|
L
|
A
|
A
|
G
|
A
|
180 |
V
|
T
|
L
|
S
|
V
|
L
|
G
|
V
|
T
|
G
|
190 |
ECL2 | TM5 | ||||||||
S
|
R
|
P
|
C
|
C
|
R
|
V
|
F
|
A
|
L
|
200 |
T
|
V
|
L
|
E
|
F
|
L
|
L
|
P
|
L
|
L
|
210 |
V
|
I
|
S
|
V
|
F
|
T
|
G
|
R
|
I
|
M
|
220 |
ICL3 | |||||||||
C
|
A
|
L
|
S
|
R
|
P
|
G
|
L
|
L
|
H
|
230 |
TM6 | |||||||||
Q
|
G
|
R
|
Q
|
R
|
R
|
V
|
R
|
A
|
M
|
240 |
Q
|
L
|
L
|
L
|
T
|
V
|
L
|
I
|
I
|
F
|
250 |
L
|
V
|
C
|
F
|
T
|
P
|
F
|
H
|
A
|
R
|
260 |
Q
|
V
|
A
|
V
|
A
|
L
|
W
|
P
|
D
|
M
|
270 |
TM7 | |||||||||
P
|
H
|
H
|
T
|
S
|
L
|
V
|
V
|
Y
|
H
|
280 |
V
|
A
|
V
|
T
|
L
|
S
|
S
|
L
|
N
|
S
|
290 |
C
|
M
|
D
|
P
|
I
|
V
|
Y
|
C
|
F
|
V
|
300 |
H8 | |||||||||
T
|
S
|
G
|
F
|
Q
|
A
|
T
|
V
|
R
|
G
|
310 |
L
|
F
|
G
|
Q
|
H
|
G
|
E
|
R
|
E
|
P
|
320 |
C-term | |||||||||
S
|
S
|
G
|
D
|
V
|
V
|
S
|
M
|
H
|
R
|
330 |
S
|
S
|
K
|
G
|
S
|
G
|
R
|
H
|
H
|
I
|
340 |
L
|
S
|
A
|
G
|
P
|
H
|
A
|
L
|
T
|
Q
|
350 |
A
|
L
|
A
|
N
|
G
|
P
|
E
|
A
|
358 |
SCHEMATIC
Perspective:
Wild-type
Construct
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
DIAGRAMS
MUTATIONS
Position | Wild-type | Mutated |
---|
DELETIONS
MODIFICATIONS
AUXILIARY PROTEINS
EXPRESSION
Expression method | Host cell type | Host cell | Remarks |
---|---|---|---|
SOLUBILIZATION
Solvent type | Item | Concentration |
---|
Remarks:
PURIFICATION
Purification type | Description |
---|
Remarks:
CRYSTALLIZATION
METHOD:
TYPE: ()
PROTEIN CONCENTRATION:
Temperature:
ph : -
Remarks:
Chemical lists
Type | Item | Concentration |
---|