Structure information

NTS1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6Z4Q

SPECIES

Rattus norvegicus

RESOLUTION

2.920

PREFERRED CHAIN

A

REFERENCE

10.1126/sciadv.abe5504

PUBLICATION DATE

Feb. 10, 2021

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
SR142948A Y146 3.29x29 TM3 polar (hydrogen bond)
SR142948A M208 ECL2 polar (hydrogen bond)
SR142948A P227 45.52x52 ECL2 hydrophobic
SR142948A P227 45.52x52 ECL2 Van der Waals
SR142948A L234 5.35x36 TM5 hydrophobic
SR142948A L234 5.35x36 TM5 Van der Waals
SR142948A I238 5.39x40 TM5 polar (hydrogen bond)
SR142948A R327 6.54x54 TM6 polar (hydrogen bond with backbone)
SR142948A R327 6.54x54 TM6 polar (charge-assisted hydrogen bond)
SR142948A R328 6.55x55 TM6 polar (charge-assisted hydrogen bond)
SR142948A M330 6.57x57 TM6 polar (hydrogen bond)
SR142948A M330 6.57x57 TM6 polar (hydrogen bond with backbone)
SR142948A F331 6.58x58 TM6 polar (hydrogen bond with backbone)
SR142948A F331 6.58x58 TM6 polar (hydrogen bond)
SR142948A I334 ECL3 polar (hydrogen bond with backbone)
SR142948A I334 ECL3 Van der Waals
SR142948A S335 ECL3 Van der Waals
SR142948A F344 ECL3 polar (hydrogen bond with backbone)
SR142948A F344 ECL3 Van der Waals
SR142948A D345 7.29x28 TM7 Van der Waals
SR142948A Y347 7.31x30 TM7 polar (hydrogen bond with backbone)
SR142948A Y347 7.31x30 TM7 Van der Waals
SR142948A H348 7.32x31 TM7 Van der Waals
SR142948A F350 7.34x33 TM7 Van der Waals
SR142948A Y351 7.35x34 TM7 polar (hydrogen bond with backbone)
SR142948A Y351 7.35x34 TM7 polar (hydrogen bond)
SR142948A Y351 7.35x34 TM7 polar (hydrogen bond)
SR142948A Y351 7.35x34 TM7 aromatic (edge-to-face)

Ligands

SR142948A

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

S N G V T G V V F L A L Y I A T V L V K 1 G S L A L S D L L I L L L A M P V E L Y N 2 S A V N L A T A Y T C A D R L F Y Y G R 3 T K K F I S A I W L A S A L L A I P M 4 N L I S I V L M P F L F S M F T N V Q I V 5 R A V V I A F V V C W L P Y H V R R L M 6 I P N I A S S V Y F L A N T L M Y F Y 7
Download: PNG | SVG
ICL1 K S L Q ICL1ECL1 H H P W A F ECL1ICL2 P F K A K T L M ICL2ECL2 G L Q N R S G D G T H P G G L V C T P I V D ECL2ICL3 R V C T V G T H N G L E H S T F N M T I E ICL3ECL3 S D E Q W ECL3N-term M H L N S S V P Q G T P G E P D A Q P F S G P Q S E M E A T F L A L S L S N G S G N T S E S D T A G P N S D L D V N T D N-termC-term P G W R H R R K K R P T F S R K P N S M S S N H A F S T S A T R E T L Y C-term I Y S K V L V T A I Y L A L F V V G T V G N S V T A F T L A R K S L Q S T V H Y H L G S L A L S D L L I L L L A M P V E L Y N F I W V G D A G C R G Y Y F L R D A C T Y A T A L N V A S L S V E R Y L A I C H S R S R T K K F I S A I W L A S A L L A I P M L F T M T A T V K V V I Q V N T F M S F L F P M L V I S I L N T V I A N K L T V M V H Q A A E Q G P G R V Q A L R H G V L V L R A V V I A F V V C W L P Y H V R R L M F C Y I T T F L F D F Y H Y F Y M L T N A L F Y V S S A I N P I L Y N L V S A N F L S L C F R Q V T L A C
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
NTS1 receptor
TM3
3x29 3.29x29 Y146
ECL2
45x52 45.52x52 P227
TM5
5x36 5.35x36 V234
5x40 5.39x40 I238
TM6
6x54 6.54x54 R327
6x55 6.55x55 R328
6x57 6.57x57 M330
6x58 6.58x58 F331
TM7
7x28 7.29x28 D345
7x30 7.31x30 Y347
7x31 7.32x31 H348
7x33 7.34x33 F350
7x34 7.35x34 Y351