Structure information

ADGRG3

PROTEIN CLASS

Class B2 (Adhesion)

PDB CODE

7D76

SPECIES

Homo sapiens

RESOLUTION

3.100

PREFERRED CHAIN

R

REFERENCE

10.1038/S41586-020-03083-W

PUBLICATION DATE

Feb. 3, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Beclomethasone F323 2.64x64 TM2 hydrophobic
Beclomethasone W490 6.53x53 TM6 hydrophobic
Beclomethasone I494 6.57x57 TM6 hydrophobic
Beclomethasone L498 ECL3 hydrophobic
Beclomethasone F506 7.42x41 TM7 hydrophobic
Beclomethasone N510 7.46x45 TM7 Van der Waals
Beclomethasone N510 7.46x45 TM7 polar (hydrogen bond)

Ligands

Beclomethasone

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Residue Diagrams

A L F I M S V G C G A Q S I R T L I H V 1 V A L G G S L F L L N L A F L V N V G S 2 L G M W T F A C L L F Y H F V A G R A W 3 Y F L K L S L G V W G L P A L M V I G T G 4 L V V M G F L F T I L F Y G H V T I Y L A 5 L G L S S L V G V T W G L A I F 6 C C I F V G Q L S N F L A F I Y V T 7
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ICL1 E R F K S ICL1ECL1 G S K G ECL1ICL2 V F N T Y F G ICL2ECL2 S Y G L Y T I R D R E N R T S L E L C W F R E G T T M ECL2ICL3 A V K E R G ICL3ECL3 T P L G L S ECL3N-term M A T P R G L G A L L L L L L L P T S G Q E K P T E G P R N T C L G S N N M Y D I F N L N D K A L C F T K C R Q S G S D S C N V E N L Q R Y W L N Y E A H L M K E G L T Q K V N T P F L K A L V Q N L S T N T A E D F Y F S L E P S Q V P R Q V M K D E D K P P D R V R L P K S L F R S L P G N R S V V R L A V T I L D I G P G T L F K G P R L G L G D G S G V L N N R L V G L S V G Q M H V T K L A E P L E I V F S H Q R P P P N M T L T C V F W D V T K G T T G D W S S E G C S T E V R P E G T V C C C D H L T F F A L L L R P T L N-termC-term L P S Q S T T V S S S T A R L D Q A H S A S Q E C-term D Q S T V H I L T R I S Q A G C G V S M I F L A F T I I L Y A F L R L S R E D A P K I H V A L G G S L F L L N L A F L V N V G S S D A A C W A R G A V F H Y F L L C A F T W M G L E A F H L Y L L A V R H Y F L K L S L V G W G L P A L M V I G T G S A N Y A L Y I T V H G Y F L I T F L F G M V V L A L V V W K I F T L S R A T K N R K K V L T L L G L S S L V G V T W G L A I F T V Y I F A L F N S L Q G V F I C C W F T I L Y
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Residue Table


GPCRdb(A)
GPCRdb(B)
ADGRG3
TM2
2x57 2.64x64 F323
TM6
6x48 6.53x53 W490
6x52 6.57x57 I494
TM7
7x37 7.42x41 F506
7x41 7.46x45 N510