Structure information

HCA2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8J6P

SPECIES

Homo sapiens

RESOLUTION

2.550

PREFERRED CHAIN

R

REFERENCE

10.1038/S41467-023-43537-Z

PUBLICATION DATE

Dec. 6, 2023

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
nicotinic acid L83 2.60x60 TM2 hydrophobic
nicotinic acid L104 3.29x29 TM3 hydrophobic
nicotinic acid L107 3.32x32 TM3 hydrophobic
nicotinic acid S179 45.52x52 ECL2 polar (hydrogen bond)
nicotinic acid S179 45.52x52 ECL2 Van der Waals
nicotinic acid F180 ECL2 hydrophobic
nicotinic acid F180 ECL2 Van der Waals
nicotinic acid L280 7.39x38 TM7 Van der Waals
nicotinic acid L280 7.39x38 TM7 hydrophobic

Ligands

nicotinic acid

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

G N G L L G F I F E L G L V P P L V K V 1 F N L A V A D F L L I I C L P F L M D N 2 V T L F I I S G Q R N M A L M F L M L R 3 A A I I S C L L W G I T I G L T V H L L 4 S C F L I I G L P L F F E L L F M A E H W 5 M V V A I V F V I C F L P S V V V R I R 6 V P D L M S N M Y T F S L T I F F A L 7
Download: PNG | SVG
ICL1 L K S W ICL1ECL1 W D W K F ECL1ICL2 P H H A L N K I ICL2ECL2 M P I Q N G G A N L C S S F S I C H T F ECL2ICL3 M D R H A ICL3ECL3 G T Q N C E V ECL3N-term M N R H H L Q D H F L E I D K K N C C V F R D D N-termC-term Q R K M T G E P D N N R S T S V E L T G D P N K T R G A P E A L M A N S G E P W S P S Y L G P T S P C-term F I V K V L P P V L G L E F I F G L L G N G L A L W I F C F H K S S R I F L F N L A V A D F L L I I C L P F L M D N Y V R R G D I P C R L M L F M L A M N R Q G S I I F L T V V A V D R Y F R V V H S N R T A A I I S C L L W G I T I G L T V H L L K K K Q W H E A M F L L E F F L P L G I I L F C S A R I I W S L R Q R Q K I K R A I T F I M V V A I V F V I C F L P S V V V R I R I F W L L H T S Y R S V D L A F F I T L S F T Y M N S M L D P V V Y Y F S S P S F S T C L F P N F L I N R
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
HCA2 receptor
TM2
2x60 2.60x60 L83
TM3
3x29 3.29x29 L104
3x32 3.32x32 L107
ECL2
45x52 45.52x52 S179
TM7
7x38 7.39x38 L280