GPCRdb

histaprodifen

Agent/drug
Bioactivity

histaprodifen

SMILES	NCCc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1
InChIKey	BPZGZNLONLANFE-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	7
Molecular weight (Da)	305.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₁

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₁	B0FL73	Guinea pig	Adrenoceptors	A	pKd	4.34	4.34	4.34	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKd	4.85	4.85	4.85	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	5.70	5.70	5.70	Guide to Pharmacology
H₁	HRH1	Rat	Histamine	A	pKd	8.04	8.04	8.04	ChEMBL
H₁	HRH1	Guinea pig	Histamine	A	pKd	8.80	8.97	9.11	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₁	HRH1	Rat	Histamine	A	pEC50	6.07	6.07	6.07	ChEMBL
H₁	HRH1	Guinea pig	Histamine	A	pEC50	5.71	6.50	6.80	ChEMBL
H₁	HRH1	Human	Histamine	A	pIC50	6.10	6.10	6.10	ChEMBL

Showing 1 to 3 of 3 entries

histaprodifen

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb
Ligand site mutations	H₁

Compound is not listed as a drug.