danuglipron [2714]



danuglipron


SMILES N#Cc1ccc(COc2cccc(C3CCN(Cc4nc5ccc(C(=O)O)cc5n4C[C@@H]4CCO4)CC3)n2)c(F)c1
InChIKey HYBAKUMPISVZQP-DEOSSOPVSA-N

Chemical Properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 9
Log P 4.888
Molecular weight (Da) 555.2
Stereochemistry info full

Database connections

Structure pdb 6X1A 7LCJ 7LCK 7LCI
Model (Boltz2) GLP-1

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

danuglipron


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 2
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 6X1A 7LCJ 7LCK 7LCI
Model (Boltz2) GLP-1

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score