ABT-299


SMILES CC(=O)OC[n+]1cccc(c1)[C@H]1SCc2n1ccc2C(=O)c1cn(c2c1ccc(c2)c1ccc(cc1)F)C(=O)N(C)C.[Cl-]
InChIKey NKIONDJYXPXFFL-JSSVAETHSA-M

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 618.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 9.5 9.5 9.5 Guide to Pharmacology
PAF PTAFR Human Platelet-activating factor A pKi 9.01 9.01 9.01 ChEMBL
PAF PTAFR Guinea pig Platelet-activating factor A pKi 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database