CHEMBL1092571


SMILES C[C@H]1CN(C(=O)[C@H]2CN(C3CCC3)C[C@@H]2c2ccc(F)cc2F)C[C@@H](C)[C@]1(O)c1ccccc1
InChIKey FTOGLQXKLWNGLW-VHNNBIRDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 468.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 6.46 6.46 6.46 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.3 6.3 6.3 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.5 7.5 7.5 ChEMBL