Initializing potency table...
Ligand source activities (1 row/activity)
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Common name | GPCRdb ID | Reference ligand | Vendors | Species | Assay Type | Activity Type | Activity Relation | Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description | Source | Mol weight | Rot Bonds | H don | H acc | LogP | Smiles | DOI | |
CHEMBL3315335 | 113371 | None | 0 | Human | Binding | IC50 | = | 4286.00 | 5.37 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 834.5 | 25 | 11 | 10 | -1.56 | CC(C)C[C@H](NC(=O)CCC1CCCCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL3356083 | 214020 | None | 12 | Human | Binding | IC50 | = | 0.78 | 9.11 | - | 4 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | - | - | - | - | - | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL3356083 | 214020 | None | 12 | Human | Binding | IC50 | = | 0.78 | 9.11 | - | 4 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | ChEMBL | - | - | - | - | - | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1021/acsmedchemlett.8b00105 | |
CHEMBL4159176 | 162077 | None | 0 | Human | Binding | IC50 | = | 100.10 | 7.00 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1140.6 | 33 | 16 | 14 | -2.37 | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N(CCc1ccc(O)cc1)CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4159554 | 162102 | None | 0 | Human | Binding | IC50 | = | 0.75 | 9.12 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | ChEMBL | 1242.7 | 35 | 16 | 13 | -0.41 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)NCc1ccccc1)C(N)=O | https://dx.doi.org/10.1021/acsmedchemlett.8b00105 | |
CHEMBL4160825 | 162177 | None | 0 | Human | Binding | IC50 | = | 0.31 | 9.51 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1160.6 | 32 | 16 | 13 | -1.27 | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4161037 | 162188 | None | 0 | Human | Binding | IC50 | = | 844.40 | 6.07 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1152.6 | 33 | 16 | 13 | -2.24 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4161095 | 162190 | None | 0 | Human | Binding | IC50 | = | 173.80 | 6.76 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1126.6 | 32 | 16 | 14 | -2.41 | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N(CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O)Cc1ccc(O)cc1 | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4161479 | 162214 | None | 0 | Human | Binding | IC50 | = | 28.10 | 7.55 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | ChEMBL | 1166.6 | 34 | 16 | 13 | -1.85 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)CC(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1021/acsmedchemlett.8b00105 | |
CHEMBL4161501 | 162217 | None | 0 | Human | Binding | IC50 | = | 68.60 | 7.16 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1156.7 | 30 | 15 | 13 | -1.81 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O)C[C@@H]2CCCC[C@@H]21 | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4161902 | 162243 | None | 0 | Human | Binding | IC50 | = | 0.88 | 9.06 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1186.6 | 33 | 15 | 12 | -0.79 | CC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4162351 | 162265 | None | 0 | Human | Binding | IC50 | = | 8.80 | 8.06 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | ChEMBL | 1178.6 | 31 | 16 | 13 | -1.93 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NC1(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O)CCc2ccccc2C1 | https://dx.doi.org/10.1021/acsmedchemlett.8b00105 | |
CHEMBL4162728 | 162297 | None | 0 | Human | Binding | IC50 | = | 0.09 | 10.04 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | ChEMBL | 1214.6 | 30 | 15 | 13 | -0.86 | CC(=O)N1Cc2cc(O)ccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1021/acsmedchemlett.8b00105 | |
CHEMBL4162868 | 162307 | None | 0 | Human | Binding | IC50 | = | 3.90 | 8.41 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1182.6 | 34 | 16 | 14 | -2.19 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N(CCc1ccc(O)cc1)CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4164026 | 162372 | None | 0 | Human | Binding | IC50 | = | 0.97 | 9.01 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1144.6 | 32 | 15 | 12 | -0.97 | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4164449 | 162400 | None | 0 | Human | Binding | IC50 | = | 3755.00 | 5.42 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1152.6 | 33 | 16 | 13 | -2.24 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4164680 | 162418 | None | 0 | Human | Binding | IC50 | = | 1167.00 | 5.93 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1110.6 | 32 | 16 | 13 | -2.42 | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4164922 | 162438 | None | 0 | Human | Binding | IC50 | = | 0.36 | 9.44 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cell membranes after 3 hrs by microscintillation counting | ChEMBL | 1196.6 | 33 | 17 | 14 | -1.92 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1016/j.ejmech.2017.12.035 | |
CHEMBL4164957 | 162441 | None | 0 | Human | Binding | IC50 | = | 37.00 | 7.43 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | ChEMBL | 1242.7 | 35 | 16 | 13 | -0.41 | CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)NCc1ccccc1 | https://dx.doi.org/10.1021/acsmedchemlett.8b00105 | |
CHEMBL4164987 | 162443 | None | 0 | Human | Binding | IC50 | = | 3.00 | 8.52 | - | 2 | Displacement of [3H]-NMU-8 from human NMUR1 expressed in HEK293 cells after 3 hrs by topcount micro scintillation counting method | ChEMBL | 1178.6 | 30 | 14 | 13 | -1.67 | CC(=O)N1Cc2cc(O)ccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N(C)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(N)=O | https://dx.doi.org/10.1021/acsmedchemlett.8b00105 |
Showing 1 to 20 of 55 entries
Ligands | Receptor | Activity | Chemical information | ||||||||||||||||||
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Common name |
GPCRdb ID |
Reference ligand |
Vendors | Species | Assay Type |
Activity Type |
Activity Relation |
Activity Value |
p-value (-log) |
Fold selectivity |
Tested GPCRs |
Assay Description |
Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI | |