Ligand source activities (1 row/activity)
Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Potency) |
# tested GPCRs (Potency) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |
Ligands | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID | #Vendors | Reference ligand |
Fold selectivity (Affinity) |
# tested GPCRs (Affinity) |
Species | p-value (-log) |
Type | Activity Relation |
Activity Value |
Assay Type | Assay Description | Source | Mol weight |
Rot Bonds |
H don | H acc | LogP | Smiles | DOI |
259210 | 148721 | 22 | None | - | 0 | Bovine | 4.4 | pEC50 | = | 4.4 | Binding | ChEMBL | 548 | 5 | 0 | 5 | 5.9 | C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 | 10.1021/jm800326q | ||
CHEMBL387152 | 148721 | 22 | None | - | 0 | Bovine | 4.4 | pEC50 | = | 4.4 | Binding | ChEMBL | 548 | 5 | 0 | 5 | 5.9 | C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 | 10.1021/jm800326q | ||
259210 | 148721 | 22 | None | - | 0 | Bovine | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 548 | 5 | 0 | 5 | 5.9 | C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 | 10.1021/jm800326q | ||
CHEMBL387152 | 148721 | 22 | None | - | 0 | Bovine | 4.8 | pIC50 | = | 4.8 | Binding | ChEMBL | 548 | 5 | 0 | 5 | 5.9 | C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)COS(=O)(=O)c1ccc(Br)cc1 | 10.1021/jm800326q |