FP receptor (pf2r_mouse)
FAMILY
Class A (Rhodopsin) Lipid receptors Prostanoid receptors FP receptor
GENE
Ptgfr
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Prostaglandin F2-alpha receptor, PGF receptor, PGF2-alpha receptor, Prostanoid FP receptor
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
S
|
M
|
N
|
S
|
S
|
K
|
Q
|
P
|
V
|
10 |
S
|
P
|
A
|
A
|
G
|
L
|
I
|
A
|
N
|
T
|
20 |
T
|
C
|
Q
|
T
|
E
|
N
|
R
|
L
|
S
|
V
|
30 |
TM1 | |||||||||
F
|
F
|
S
|
I
|
I
|
F
|
M
|
T
|
V
|
G
|
40 |
I
|
L
|
S
|
N
|
S
|
L
|
A
|
I
|
A
|
I
|
50 |
L
|
M
|
K
|
A
|
Y
|
Q
|
R
|
F
|
R
|
Q
|
60 |
ICL1 | TM2 | ||||||||
K
|
S
|
K
|
A
|
S
|
F
|
L
|
L
|
L
|
A
|
70 |
S
|
G
|
L
|
V
|
I
|
T
|
D
|
F
|
F
|
G
|
80 |
H
|
L
|
I
|
N
|
G
|
G
|
I
|
A
|
V
|
F
|
90 |
ECL1 | |||||||||
V
|
Y
|
A
|
S
|
D
|
K
|
D
|
W
|
I
|
R
|
100 |
TM3 | |||||||||
F
|
D
|
Q
|
S
|
N
|
I
|
L
|
C
|
S
|
I
|
110 |
F
|
G
|
I
|
S
|
M
|
V
|
F
|
S
|
G
|
L
|
120 |
C
|
P
|
L
|
F
|
L
|
G
|
S
|
A
|
M
|
A
|
130 |
I
|
E
|
R
|
C
|
I
|
G
|
V
|
T
|
N
|
P
|
140 |
ICL2 | TM4 | ||||||||
I
|
F
|
H
|
S
|
T
|
K
|
I
|
T
|
S
|
K
|
150 |
H
|
V
|
K
|
M
|
I
|
L
|
S
|
G
|
V
|
C
|
160 |
M
|
F
|
A
|
V
|
F
|
V
|
A
|
V
|
L
|
P
|
170 |
ECL2 | |||||||||
I
|
L
|
G
|
H
|
R
|
D
|
Y
|
Q
|
I
|
Q
|
180 |
A
|
S
|
R
|
T
|
W
|
C
|
F
|
Y
|
N
|
T
|
190 |
TM5 | |||||||||
E
|
H
|
I
|
E
|
D
|
W
|
E
|
D
|
R
|
F
|
200 |
Y
|
L
|
L
|
F
|
F
|
S
|
F
|
L
|
G
|
L
|
210 |
L
|
A
|
L
|
G
|
V
|
S
|
F
|
S
|
C
|
N
|
220 |
A
|
V
|
T
|
G
|
V
|
T
|
L
|
L
|
R
|
V
|
230 |
ICL3 | |||||||||
K
|
F
|
R
|
S
|
Q
|
Q
|
H
|
R
|
Q
|
G
|
240 |
TM6 | |||||||||
R
|
S
|
H
|
H
|
L
|
E
|
M
|
I
|
I
|
Q
|
250 |
L
|
L
|
A
|
I
|
M
|
C
|
V
|
S
|
C
|
V
|
260 |
C
|
W
|
S
|
P
|
F
|
L
|
V
|
T
|
M
|
A
|
270 |
ECL3 | |||||||||
N
|
I
|
A
|
I
|
N
|
G
|
N
|
N
|
S
|
P
|
280 |
TM7 | |||||||||
V
|
T
|
C
|
E
|
T
|
T
|
L
|
F
|
A
|
L
|
290 |
R
|
M
|
A
|
T
|
W
|
N
|
Q
|
I
|
L
|
D
|
300 |
H8 | |||||||||
P
|
W
|
V
|
Y
|
I
|
L
|
L
|
R
|
K
|
A
|
310 |
V
|
L
|
R
|
N
|
L
|
Y
|
K
|
L
|
A
|
S
|
320 |
R
|
C
|
C
|
G
|
V
|
N
|
I
|
I
|
S
|
L
|
330 |
C-term | |||||||||
H
|
I
|
W
|
E
|
L
|
S
|
S
|
I
|
K
|
N
|
340 |
S
|
L
|
K
|
V
|
A
|
A
|
I
|
S
|
E
|
S
|
350 |
P
|
A
|
A
|
E
|
K
|
E
|
S
|
Q
|
Q
|
A
|
360 |
S
|
S
|
E
|
A
|
G
|
L
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
PGF2α, PGD2, PGE2
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available