BB3 receptor (brs3_human)
FAMILY
Class A (Rhodopsin) Peptide receptors Bombesin receptors BB3 receptor
GENE
BRS3
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Bombesin receptor subtype-3, BRS-3
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
A
|
Q
|
R
|
Q
|
P
|
H
|
S
|
P
|
N
|
10 |
Q
|
T
|
L
|
I
|
S
|
I
|
T
|
N
|
D
|
T
|
20 |
E
|
S
|
S
|
S
|
S
|
V
|
V
|
S
|
N
|
D
|
30 |
N
|
T
|
N
|
K
|
G
|
W
|
S
|
G
|
D
|
N
|
40 |
TM1 | |||||||||
S
|
P
|
G
|
I
|
E
|
A
|
L
|
C
|
A
|
I
|
50 |
Y
|
I
|
T
|
Y
|
A
|
V
|
I
|
I
|
S
|
V
|
60 |
G
|
I
|
L
|
G
|
N
|
A
|
I
|
L
|
I
|
K
|
70 |
ICL1 | |||||||||
V
|
F
|
F
|
K
|
T
|
K
|
S
|
M
|
Q
|
T
|
80 |
TM2 | |||||||||
V
|
P
|
N
|
I
|
F
|
I
|
T
|
S
|
L
|
A
|
90 |
F
|
G
|
D
|
L
|
L
|
L
|
L
|
L
|
T
|
C
|
100 |
V
|
P
|
V
|
D
|
A
|
T
|
H
|
Y
|
L
|
A
|
110 |
ECL1 | TM3 | ||||||||
E
|
G
|
W
|
L
|
F
|
G
|
R
|
I
|
G
|
C
|
120 |
K
|
V
|
L
|
S
|
F
|
I
|
R
|
L
|
T
|
S
|
130 |
V
|
G
|
V
|
S
|
V
|
F
|
T
|
L
|
T
|
I
|
140 |
L
|
S
|
A
|
D
|
R
|
Y
|
K
|
A
|
V
|
V
|
150 |
ICL2 | |||||||||
K
|
P
|
L
|
E
|
R
|
Q
|
P
|
S
|
N
|
A
|
160 |
TM4 | |||||||||
I
|
L
|
K
|
T
|
C
|
V
|
K
|
A
|
G
|
C
|
170 |
V
|
W
|
I
|
V
|
S
|
M
|
I
|
F
|
A
|
L
|
180 |
ECL2 | |||||||||
P
|
E
|
A
|
I
|
F
|
S
|
N
|
V
|
Y
|
T
|
190 |
F
|
R
|
D
|
P
|
N
|
K
|
N
|
M
|
T
|
F
|
200 |
E
|
S
|
C
|
T
|
S
|
Y
|
P
|
V
|
S
|
K
|
210 |
TM5 | |||||||||
K
|
L
|
L
|
Q
|
E
|
I
|
H
|
S
|
L
|
L
|
220 |
C
|
F
|
L
|
V
|
F
|
Y
|
I
|
I
|
P
|
L
|
230 |
S
|
I
|
I
|
S
|
V
|
Y
|
Y
|
S
|
L
|
I
|
240 |
A
|
R
|
T
|
L
|
Y
|
K
|
S
|
T
|
L
|
N
|
250 |
ICL3 | TM6 | ||||||||
I
|
P
|
T
|
E
|
E
|
Q
|
S
|
H
|
A
|
R
|
260 |
K
|
Q
|
I
|
E
|
S
|
R
|
K
|
R
|
I
|
A
|
270 |
R
|
T
|
V
|
L
|
V
|
L
|
V
|
A
|
L
|
F
|
280 |
A
|
L
|
C
|
W
|
L
|
P
|
N
|
H
|
L
|
L
|
290 |
Y
|
L
|
Y
|
H
|
S
|
F
|
T
|
S
|
Q
|
T
|
300 |
ECL3 | TM7 | ||||||||
Y
|
V
|
D
|
P
|
S
|
A
|
M
|
H
|
F
|
I
|
310 |
F
|
T
|
I
|
F
|
S
|
R
|
V
|
L
|
A
|
F
|
320 |
S
|
N
|
S
|
C
|
V
|
N
|
P
|
F
|
A
|
L
|
330 |
H8 | |||||||||
Y
|
W
|
L
|
S
|
K
|
S
|
F
|
Q
|
K
|
H
|
340 |
F
|
K
|
A
|
Q
|
L
|
F
|
C
|
C
|
K
|
A
|
350 |
C-term | |||||||||
E
|
R
|
P
|
E
|
P
|
P
|
V
|
A
|
D
|
T
|
360 |
S
|
L
|
T
|
T
|
L
|
A
|
V
|
M
|
G
|
T
|
370 |
V
|
P
|
G
|
T
|
G
|
S
|
I
|
Q
|
M
|
S
|
380 |
E
|
I
|
S
|
V
|
T
|
S
|
F
|
T
|
G
|
C
|
390 |
S
|
V
|
K
|
Q
|
A
|
E
|
D
|
R
|
F
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
Found 2 structure(s) - view all details on the Structures page