C5a1 receptor (c5ar1_mouse)
FAMILY
Class A (Rhodopsin) Peptide receptors Complement peptide receptors C5a1 receptor
GENE
C5ar1 (C5ar, C5r1)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, CD88
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
D
|
P
|
I
|
D
|
N
|
S
|
S
|
F
|
E
|
10 |
I
|
N
|
Y
|
D
|
H
|
Y
|
G
|
T
|
M
|
D
|
20 |
P
|
N
|
I
|
P
|
A
|
D
|
G
|
I
|
H
|
L
|
30 |
TM1 | |||||||||
P
|
K
|
R
|
Q
|
P
|
G
|
D
|
V
|
A
|
A
|
40 |
L
|
I
|
I
|
Y
|
S
|
V
|
V
|
F
|
L
|
V
|
50 |
G
|
V
|
P
|
G
|
N
|
A
|
L
|
V
|
V
|
W
|
60 |
ICL1 | |||||||||
V
|
T
|
A
|
F
|
E
|
A
|
R
|
R
|
A
|
V
|
70 |
TM2 | |||||||||
N
|
A
|
I
|
W
|
F
|
L
|
N
|
L
|
A
|
V
|
80 |
A
|
D
|
L
|
L
|
S
|
C
|
L
|
A
|
L
|
P
|
90 |
V
|
L
|
F
|
T
|
T
|
V
|
L
|
N
|
H
|
N
|
100 |
ECL1 | TM3 | ||||||||
Y
|
W
|
Y
|
F
|
D
|
A
|
T
|
A
|
C
|
I
|
110 |
V
|
L
|
P
|
S
|
L
|
I
|
L
|
L
|
N
|
M
|
120 |
Y
|
A
|
S
|
I
|
L
|
L
|
L
|
A
|
T
|
I
|
130 |
S
|
A
|
D
|
R
|
F
|
L
|
L
|
V
|
F
|
K
|
140 |
ICL2 | |||||||||
P
|
I
|
W
|
C
|
Q
|
K
|
V
|
R
|
G
|
T
|
150 |
TM4 | |||||||||
G
|
L
|
A
|
W
|
M
|
A
|
C
|
G
|
V
|
A
|
160 |
W
|
V
|
L
|
A
|
L
|
L
|
L
|
T
|
I
|
P
|
170 |
ECL2 | |||||||||
S
|
F
|
V
|
Y
|
R
|
E
|
A
|
Y
|
K
|
D
|
180 |
F
|
Y
|
S
|
E
|
H
|
T
|
V
|
C
|
G
|
I
|
190 |
TM5 | |||||||||
N
|
Y
|
G
|
G
|
G
|
S
|
F
|
P
|
K
|
E
|
200 |
K
|
A
|
V
|
A
|
I
|
L
|
R
|
L
|
M
|
V
|
210 |
G
|
F
|
V
|
L
|
P
|
L
|
L
|
T
|
L
|
N
|
220 |
I
|
C
|
Y
|
T
|
F
|
L
|
L
|
L
|
R
|
T
|
230 |
ICL3 | |||||||||
W
|
S
|
R
|
K
|
A
|
T
|
R
|
S
|
T
|
K
|
240 |
TM6 | |||||||||
T
|
L
|
K
|
V
|
V
|
M
|
A
|
V
|
V
|
I
|
250 |
C
|
F
|
F
|
I
|
F
|
W
|
L
|
P
|
Y
|
Q
|
260 |
V
|
T
|
G
|
V
|
M
|
I
|
A
|
W
|
L
|
P
|
270 |
ECL3 | TM7 | ||||||||
P
|
S
|
S
|
P
|
T
|
L
|
K
|
R
|
V
|
E
|
280 |
K
|
L
|
N
|
S
|
L
|
C
|
V
|
S
|
L
|
A
|
290 |
Y
|
I
|
N
|
C
|
C
|
V
|
N
|
P
|
I
|
I
|
300 |
H8 | |||||||||
Y
|
V
|
M
|
A
|
G
|
Q
|
G
|
F
|
H
|
G
|
310 |
R
|
L
|
L
|
R
|
S
|
L
|
P
|
S
|
I
|
I
|
320 |
C-term | |||||||||
R
|
N
|
A
|
L
|
S
|
E
|
D
|
S
|
V
|
G
|
330 |
R
|
D
|
S
|
K
|
T
|
F
|
T
|
P
|
S
|
T
|
340 |
T
|
D
|
T
|
S
|
T
|
R
|
K
|
S
|
Q
|
A
|
350 |
V
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models have been generated as experimental structures are available (see below).
STRUCTURES
Found 2 structure(s) - view all details on the Structures page