OR51E1 (o51e1_human)

FAMILY

Class O1 (fish-like odorant) Odorant receptors Odorant family 51 OR51E1

GENE

OR51E1 (GPR164, OR51E1P, OR52A3P, POGR, PSGR2)

ORGANISM

Human (Homo sapiens)

ALT. NAMES

Olfactory receptor 51E1, D-GPCR, G-protein coupled receptor 164, Olfactory receptor 52A3, Prostate-overexpressed G protein-coupled receptor, Prostate-specific G protein-coupled receptor 2

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
V
D
P
N
G
N
E
S
S
10
                   
A
T
Y
F
I
L
I
G
L
P
20
          TM1    
G
L
E
E
A
Q
F
W
L
A
30
                   
F
P
L
C
S
L
Y
L
I
A
40
                   
V
L
G
N
L
T
I
I
Y
I
50
        ICL1    
V
R
T
E
H
S
L
H
E
P
60
TM2              
M
Y
I
F
L
C
M
L
S
G
70
                   
I
D
I
L
I
S
T
S
S
M
80
                   
P
K
M
L
A
I
F
W
F
N
90
ECL1 TM3      
S
T
T
I
Q
F
D
A
C
L
100
                   
L
Q
M
F
A
I
H
S
L
S
110
                   
G
M
E
S
T
V
L
L
A
M
120
                   
A
F
D
R
Y
V
A
I
C
H
130
ICL2            
P
L
R
H
A
T
V
L
T
L
140
TM4              
P
R
V
T
K
I
G
V
A
A
150
                   
V
V
R
G
A
A
L
M
A
P
160
                   
L
P
V
F
I
K
Q
L
P
F
170
ECL2            
C
R
S
N
I
L
S
H
S
Y
180
                   
C
L
H
Q
D
V
M
K
L
A
190
      TM5        
C
D
D
I
R
V
N
V
V
Y
200
                   
G
L
I
V
I
I
S
A
I
G
210
                   
L
D
S
L
L
I
S
F
S
Y
220
                   
L
L
I
L
K
T
V
L
G
L
230
TM6              
T
R
E
A
Q
A
K
A
F
G
240
                   
T
C
V
S
H
V
C
A
V
F
250
                   
I
F
Y
V
P
F
I
G
L
S
260
            ECL3
M
V
H
R
F
S
K
R
R
D
270
TM7              
S
P
L
P
V
I
L
A
N
I
280
                   
Y
L
L
V
P
P
V
L
N
P
290
            H8    
I
V
Y
G
V
K
T
K
E
I
300
                   
R
Q
R
I
L
R
L
F
H
V
310
C-term  
A
T
H
A
S
E
P

LINKS

Guide To Pharmacology

UniProt

DIAGRAMS

ICL1 H S L H ICL1ECL1 S T T I ECL1ICL2 P L R H A T V L ICL2ECL2 P F C R S N I L S H S Y C L H Q D V M K L A C D D ECL2ECL3 K R R ECL3N-term M V D P N G N E S S A T Y F I L I G L P G L E E A N-termC-term A T H A S E P C-term Q F W L A F P L C S L Y L I A V L G N L T I I Y I V R T E E P M Y I F L C M L S G I D I L I S T S S M P K M L A I F W F N Q F D A C L L Q M F A I H S L S G M E S T V L L A M A F D R Y V A I C H T L P R V T K I G V A A V V R G A A L M A P L P V F I K Q L I R V N V V Y G L I V I I S A I G L D S L L I S F S Y L L I L K T V L G L T R E A Q A K A F G T C V S H V C A V F I F Y V P F I G L S M V H R F S D S P L P V I L A N I Y L L V P P V L N P I V Y G V K T K E I L R I R Q R L F H V
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L N G L V A I L Y L S C L P F A L W F Q 1 C M L S G I D I L I S T S S M P K M L A 2 A L L V T S E M G S L S H I A F M Q L L 3 V T K I G V A A V V R G A A L M A P L P 4 Y S F S I L L S D L G I A S I I V I L G Y 5 V S H V C A V F I F Y V P F I G L S M V 6 I P N L V P P V L L Y I N A L I V P L 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

o51e1_human inactive,

o51e1_human active

STRUCTURES

No structures available